Result of FASTA (omim) for
pF1KB6841
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6841, 172 aa
1>>>pF1KB6841 172 - 172 aa - 172 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9319+/-0.000252; mu= 16.7098+/- 0.016
mean_var=86.5621+/-17.712, 0's: 0 Z-trim(122.3): 65 B-trim: 1997 in 1/57
Lambda= 0.137851
statistics sampled from 40247 (40315) to 40247 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.82), E-opt: 0.2 (0.473), width: 16
Scan time: 5.630
The best scores are: opt bits E(85289)
NP_982260 (OMIM: 609155) achaete-scute homolog 4 [ ( 173) 1179 242.9 2e-64
NP_065697 (OMIM: 609154) achaete-scute homolog 3 [ ( 181) 308 69.7 2.8e-12
NP_005161 (OMIM: 601886) achaete-scute homolog 2 [ ( 193) 268 61.7 7.3e-10
NP_004307 (OMIM: 100790,209880) achaete-scute homo ( 236) 254 59.1 5.8e-09
NP_803238 (OMIM: 608606) class A basic helix-loop- ( 189) 182 44.6 0.0001
NP_001004311 (OMIM: 608697,612310) factor in the g ( 219) 179 44.1 0.00017
NP_005089 (OMIM: 603628) musculin [Homo sapiens] ( 206) 174 43.1 0.00032
NP_835455 (OMIM: 607194,609069,615935) pancreas tr ( 328) 175 43.5 0.00039
NP_001073983 (OMIM: 609067) basic helix-loop-helix ( 201) 168 41.9 0.00073
XP_006716679 (OMIM: 609067) PREDICTED: basic helix ( 201) 168 41.9 0.00073
NP_006152 (OMIM: 601726) neurogenin-1 [Homo sapien ( 237) 163 41.0 0.0016
NP_068808 (OMIM: 602407) heart- and neural crest d ( 217) 161 40.5 0.002
XP_005259969 (OMIM: 151440) PREDICTED: protein lyl ( 206) 160 40.3 0.0022
NP_005574 (OMIM: 151440) protein lyl-1 [Homo sapie ( 280) 160 40.4 0.0028
NP_004600 (OMIM: 601010) transcription factor 15 [ ( 199) 158 39.9 0.0029
XP_016882306 (OMIM: 151440) PREDICTED: protein lyl ( 302) 160 40.5 0.0029
XP_016882305 (OMIM: 151440) PREDICTED: protein lyl ( 351) 160 40.5 0.0032
NP_005412 (OMIM: 186855,613065) T-cell acute lymph ( 108) 153 38.6 0.0038
XP_005268588 (OMIM: 602406) PREDICTED: heart- and ( 214) 155 39.3 0.0046
NP_004812 (OMIM: 602406) heart- and neural crest d ( 215) 155 39.3 0.0046
NP_005163 (OMIM: 601461) protein atonal homolog 1 ( 354) 155 39.6 0.0064
NP_002469 (OMIM: 159970) myoblast determination pr ( 320) 154 39.3 0.0069
NP_001157877 (OMIM: 607539,609432,615416) class A ( 235) 152 38.8 0.0074
>>NP_982260 (OMIM: 609155) achaete-scute homolog 4 [Homo (173 aa)
initn: 1179 init1: 1179 opt: 1179 Z-score: 1277.8 bits: 242.9 E(85289): 2e-64
Smith-Waterman score: 1179; 100.0% identity (100.0% similar) in 172 aa overlap (1-172:2-173)
10 20 30 40 50
pF1KB6 METRKPAERLALPYSLRTAPLGVPGTLPGLPRRDPLRVALRLDAACWEWARSGCARGWQ
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_982 MMETRKPAERLALPYSLRTAPLGVPGTLPGLPRRDPLRVALRLDAACWEWARSGCARGWQ
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 YLPVPLDSAFEPAFLRKRNERERQRVRCVNEGYARLRDHLPRELADKRLSKVETLRAAID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_982 YLPVPLDSAFEPAFLRKRNERERQRVRCVNEGYARLRDHLPRELADKRLSKVETLRAAID
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 YIKHLQELLERQAWGLEGAAGAVPQRRAECNSDGESKASSAPSPSSEPEEGGS
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_982 YIKHLQELLERQAWGLEGAAGAVPQRRAECNSDGESKASSAPSPSSEPEEGGS
130 140 150 160 170
>>NP_065697 (OMIM: 609154) achaete-scute homolog 3 [Homo (181 aa)
initn: 300 init1: 300 opt: 308 Z-score: 341.4 bits: 69.7 E(85289): 2.8e-12
Smith-Waterman score: 308; 47.3% identity (61.2% similar) in 129 aa overlap (9-128:22-149)
10 20 30 40
pF1KB6 METRKPAERLALPYSLRTAPLGVPGTLPGLPRRDPLRVAL-RL----
:: : :. :. . . : : .: : ::
NP_065 MMDNRGNSSLPDKLPIFPDSARLPLTRSFYLEPMVTFHVHPEAPVSSPYSEELPRLPFPS
10 20 30 40 50 60
50 60 70 80 90
pF1KB6 DAACWEWARSGCARGWQYLPVP----LDSAFEPAFLRKRNERERQRVRCVNEGYARLRDH
:. : .. .: : . .. ::: :::::::::::.:::::::.:: :
NP_065 DSLILGNYSEPCPFSFP-MPYPNYRGCEYSYGPAFTRKRNERERQRVKCVNEGYAQLRHH
70 80 90 100 110
100 110 120 130 140 150
pF1KB6 LPRELADKRLSKVETLRAAIDYIKHLQELLERQAWGLEGAAGAVPQRRAECNSDGESKAS
::.: .::::::::::::: ::..:: ::
NP_065 LPEEYLEKRLSKVETLRAAIKYINYLQSLLYPDKAETKNNPGKVSSMIATTSHHADPMFR
120 130 140 150 160 170
>>NP_005161 (OMIM: 601886) achaete-scute homolog 2 [Homo (193 aa)
initn: 237 init1: 207 opt: 268 Z-score: 298.0 bits: 61.7 E(85289): 7.3e-10
Smith-Waterman score: 268; 41.0% identity (62.2% similar) in 156 aa overlap (25-172:4-155)
10 20 30 40 50
pF1KB6 METRKPAERLALPYSLRTAPLGVPGTLP-GLPRRDPLRV--ALRLDAACWEWARSGCARG
:::: . : :. : : : : : : :.:
NP_005 MDGGTLPRSAPPAPPVPVGCAARRRPASPELLR--CSR-
10 20 30
60 70 80 90 100 110
pF1KB6 WQYLPVPLDSAFEPAFLRKRNERERQRVRCVNEGYARLRDHLPRELADKRLSKVETLRAA
. :. ... : . .::::::.::. :: :. ::.:.:. :.:.::::::::.:
NP_005 -RRRPATAETGGGAAAVARRNERERNRVKLVNLGFQALRQHVPHGGASKKLSKVETLRSA
40 50 60 70 80 90
120 130 140 150 160 170
pF1KB6 IDYIKHLQELL-ERQAWGLEGAAGAVPQR---RAECNSDGESKASSAPS-PSSEPEEGGS
..::. ::.:: :..: :.: :: : . : . ....:: :: : .:::
NP_005 VEYIRALQRLLAEHDAVRNALAGGLRPQAVRPSAPRGPPGTTPVAASPSRASSSPGRGGS
100 110 120 130 140 150
NP_005 SEPGSPRSAYSSDDSGCEGALSPAERELLDFSSWLGGY
160 170 180 190
>>NP_004307 (OMIM: 100790,209880) achaete-scute homolog (236 aa)
initn: 234 init1: 234 opt: 254 Z-score: 281.9 bits: 59.1 E(85289): 5.8e-09
Smith-Waterman score: 254; 38.9% identity (60.5% similar) in 162 aa overlap (16-170:66-217)
10 20 30 40
pF1KB6 METRKPAERLALPYSLRTAPLGVPGTLPGLPRRDPLRVALRLDAA
:: : : :. : . : .: : ..
NP_004 AAAAAAAAAAAAQSAQQQQQQQQQQQQAPQLRPAADGQPSG--GGHKSAPKQVK-RQRSS
40 50 60 70 80 90
50 60 70 80 90 100
pF1KB6 CWEWARSGCAR-----GWQYLPVPLDSAFEPAFLRKRNERERQRVRCVNEGYARLRDHLP
: : : : :. : .: . .:: . .::::::.::. :: :.: ::.:.:
NP_004 SPELMR--CKRRLNFSGFGY-SLPQQ---QPAAVARRNERERNRVKLVNLGFATLREHVP
100 110 120 130 140
110 120 130 140 150
pF1KB6 RELADKRLSKVETLRAAIDYIKHLQELL-ERQAWGLEGAAGAV-PQRRAECNSDGESKAS
:.:..:::::::.:..::. ::.:: :..: . ::.. : . ..: .: :.
NP_004 NGAANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQAGVLSPTISPNYSNDLNSMAG
150 160 170 180 190 200
160 170
pF1KB6 SAPSPSSEPEEGGS
: : : .::
NP_004 S-PVSSYSSDEGSYDPLSPEEQELLDFTNWF
210 220 230
>>NP_803238 (OMIM: 608606) class A basic helix-loop-heli (189 aa)
initn: 208 init1: 152 opt: 182 Z-score: 205.7 bits: 44.6 E(85289): 0.0001
Smith-Waterman score: 182; 32.7% identity (55.8% similar) in 147 aa overlap (2-144:4-148)
10 20 30 40 50
pF1KB6 METRKPAERLALPYSLRTAPLGVP-GTLPGLPRRDPLRVALRLDAACWEWARSGCARG
..: : .: . . : :.: :.::. : .: . .:: : : .:
NP_803 MKTKNRPPRRRAPVQDTEATPGEGTPDGSLPN-PGPEPAK-GLRSRPARAAARAPGEGRR
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 WQYLPVPLDSAFEPAFLRK--RNERERQRVRCVNEGYARLRDHLPRELADKRLSKVETLR
. : . . .. :. :::::::.. .:... ::. .:. :::.:::.:::
NP_803 RRPGPSGPGGRRDSSIQRRLESNERERQRMHKLNNAFQALREVIPHVRADKKLSKIETLT
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 AAIDYIKHLQE-LLERQAWGLEGAAGAVPQRRAECNSDGESKASSAPSPSSEPEEGGS
: .::: : .: .. : : : :.
NP_803 LAKNYIKSLTATILTMSSSRLPGLEGPGPKLYQHYQQQQQVAGGALGATEAQPQGHLQRY
120 130 140 150 160 170
>>NP_001004311 (OMIM: 608697,612310) factor in the germl (219 aa)
initn: 184 init1: 138 opt: 179 Z-score: 201.7 bits: 44.1 E(85289): 0.00017
Smith-Waterman score: 179; 30.8% identity (60.3% similar) in 146 aa overlap (20-160:10-149)
10 20 30 40 50 60
pF1KB6 METRKPAERLALPYSLRTAPLGVPGTLPGLPRRDPLRVALRLDAACWEWARSGCARGWQY
: ..: .: : :. . :. .:: . . . : .
NP_001 MDPAPGVLDPRAAPPALLGTPQAEVLEDVLREQFGPLPQLAAVCR--LKR
10 20 30 40
70 80 90 100 110
pF1KB6 LPVPLDSAFEPAFL---RKR--NERERQRVRCVNEGYARLRDHLPRELADKRLSKVETLR
:: :. : : :.: : .::.:.. .:.:.:::. .: ... :::. :.
NP_001 LPSGGYSSTENLQLVLERRRVANAKERERIKNLNRGFARLKALVPFLPQSRKPSKVDILK
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB6 AAIDYIKHLQELLERQAWGLEGAAGAVPQRRAECNSDGESKASSAPSPSSEPEEGGS
.: .::. :..::: : . . :.... :...::..:::
NP_001 GATEYIQVLSDLLE----GAKDSKKQDPDEQSYSNNSSESHTSSARQLSRNITQHISCAF
110 120 130 140 150 160
NP_001 GLKNEEEGPWADGGSGEPAHACRHSVMSTTEIISPTRSLDRFPEVELLSHRLPQV
170 180 190 200 210
>>NP_005089 (OMIM: 603628) musculin [Homo sapiens] (206 aa)
initn: 146 init1: 146 opt: 174 Z-score: 196.7 bits: 43.1 E(85289): 0.00032
Smith-Waterman score: 174; 35.7% identity (56.2% similar) in 112 aa overlap (21-129:61-164)
10 20 30 40 50
pF1KB6 METRKPAERLALPYSLRTAPLGVPGTLPGLPRRDPLRVALRLDAACWEWA
::. :. : :. : ::: :.
NP_005 LRGVERSYASPSDNSSAEEEDPDGEEERCALGTAGSAEGCKRKRP-RVAGGGGAG-----
40 50 60 70 80
60 70 80 90 100
pF1KB6 RSGCARGWQYLPVPLDSAFEPAFLRKRNE---RERQRVRCVNEGYARLRDHLPRELADKR
: : : :.: .. .:: ::: :.: ......::. :: : .
NP_005 --GSAGGGGKKPLPAKGSAAECKQSQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTK
90 100 110 120 130 140
110 120 130 140 150 160
pF1KB6 LSKVETLRAAIDYIKHLQELLERQAWGLEGAAGAVPQRRAECNSDGESKASSAPSPSSEP
:::..::: : .:: ::..::.
NP_005 LSKLDTLRLASSYIAHLRQLLQEDRYENGYVHPVNLTWPFVVSGRPDSDTKEVSAANRLC
150 160 170 180 190 200
>>NP_835455 (OMIM: 607194,609069,615935) pancreas transc (328 aa)
initn: 203 init1: 166 opt: 175 Z-score: 195.3 bits: 43.5 E(85289): 0.00039
Smith-Waterman score: 176; 36.2% identity (61.0% similar) in 105 aa overlap (78-170:169-272)
50 60 70 80 90 100
pF1KB6 EWARSGCARGWQYLPVPLDSAFEPAFLRKRNERERQRVRCVNEGYARLRDHLPRELADKR
: :::.:.. .:... ::.:.: .::
NP_835 RGLSGAAAAAARRRRRVRSEAELQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKR
140 150 160 170 180 190
110 120 130 140 150
pF1KB6 LSKVETLRAAIDYIKHLQELLER----QAWGLEGAAGAVPQRRAECNSDGES--------
::::.::: :: ::. :.::.. .. : : .: : .: : .
NP_835 LSKVDTLRLAIGYINFLSELVQADLPLRGGGAGGCGGPGGGGRLGGDSPGSQAQKVIICH
200 210 220 230 240 250
160 170
pF1KB6 KASSAPSPSSEPEEGGS
... .:::: .:. :
NP_835 RGTRSPSPS-DPDYGLPPLAGHSLSWTDEKQLKEQNIIRTAKVWTPEDPRKLNSKSSFNN
260 270 280 290 300 310
>>NP_001073983 (OMIM: 609067) basic helix-loop-helix tra (201 aa)
initn: 184 init1: 163 opt: 168 Z-score: 190.3 bits: 41.9 E(85289): 0.00073
Smith-Waterman score: 174; 38.2% identity (56.9% similar) in 102 aa overlap (70-167:73-165)
40 50 60 70 80 90
pF1KB6 LRLDAACWEWARSGCARGWQYLPVPLDSAFEPAFLRKRNERERQRVRCVNEGYARLRDHL
:: . : :::.:. :: ... :: .
NP_001 HAARCGLQGARRRAGGRRAGGGGPGGRPGREPRQRHTANARERDRTNSVNTAFTALRTLI
50 60 70 80 90 100
100 110 120 130 140 150
pF1KB6 PRELADKRLSKVETLRAAIDYIKHLQELLERQAWGLEGAAGAVPQRRAECNSDGE----S
: : ::..:::.:::: : .::.:: ..: : : : . : :.: .
NP_001 PTEPADRKLSKIETLRLASSYISHLGNVL------LAGEACGDGQ---PCHSGPAFFHAA
110 120 130 140 150
160 170
pF1KB6 KASSAPSPSSEPEEGGS
.:.: : : :
NP_001 RAGSPPPPPPPPPARDGENTQPKQICTFCLSNQRKLSKDRDRKTAIRS
160 170 180 190 200
>>XP_006716679 (OMIM: 609067) PREDICTED: basic helix-loo (201 aa)
initn: 184 init1: 163 opt: 168 Z-score: 190.3 bits: 41.9 E(85289): 0.00073
Smith-Waterman score: 174; 38.2% identity (56.9% similar) in 102 aa overlap (70-167:73-165)
40 50 60 70 80 90
pF1KB6 LRLDAACWEWARSGCARGWQYLPVPLDSAFEPAFLRKRNERERQRVRCVNEGYARLRDHL
:: . : :::.:. :: ... :: .
XP_006 HAARCGLQGARRRAGGRRAGGGGPGGRPGREPRQRHTANARERDRTNSVNTAFTALRTLI
50 60 70 80 90 100
100 110 120 130 140 150
pF1KB6 PRELADKRLSKVETLRAAIDYIKHLQELLERQAWGLEGAAGAVPQRRAECNSDGE----S
: : ::..:::.:::: : .::.:: ..: : : : . : :.: .
XP_006 PTEPADRKLSKIETLRLASSYISHLGNVL------LAGEACGDGQ---PCHSGPAFFHAA
110 120 130 140 150
160 170
pF1KB6 KASSAPSPSSEPEEGGS
.:.: : : :
XP_006 RAGSPPPPPPPPPARDGENTQPKQICTFCLSNQRKLSKDRDRKTAIRS
160 170 180 190 200
172 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 18:18:46 2016 done: Sat Nov 5 18:18:47 2016
Total Scan time: 5.630 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]