FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6845, 175 aa 1>>>pF1KB6845 175 - 175 aa - 175 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.4964+/-0.000646; mu= 17.4667+/- 0.039 mean_var=67.1507+/-13.375, 0's: 0 Z-trim(111.9): 94 B-trim: 401 in 2/51 Lambda= 0.156512 statistics sampled from 12666 (12775) to 12666 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.766), E-opt: 0.2 (0.392), width: 16 Scan time: 1.730 The best scores are: opt bits E(32554) CCDS1965.1 REG3A gene_id:5068|Hs108|chr2 ( 175) 1236 287.0 4e-78 CCDS1962.1 REG3G gene_id:130120|Hs108|chr2 ( 175) 1094 254.9 1.8e-68 CCDS1964.1 REG1A gene_id:5967|Hs108|chr2 ( 166) 588 140.6 4.3e-34 CCDS1963.1 REG1B gene_id:5968|Hs108|chr2 ( 166) 564 135.2 1.9e-32 CCDS58714.1 REG3G gene_id:130120|Hs108|chr2 ( 129) 403 98.8 1.4e-21 CCDS906.1 REG4 gene_id:83998|Hs108|chr1 ( 158) 310 77.9 3.3e-15 CCDS81953.1 CLEC19A gene_id:728276|Hs108|chr16 ( 186) 257 66.0 1.5e-11 >>CCDS1965.1 REG3A gene_id:5068|Hs108|chr2 (175 aa) initn: 1236 init1: 1236 opt: 1236 Z-score: 1516.0 bits: 287.0 E(32554): 4e-78 Smith-Waterman score: 1236; 100.0% identity (100.0% similar) in 175 aa overlap (1-175:1-175) 10 20 30 40 50 60 pF1KB6 MLPPMALPSVSWMLLSCLMLLSQVQGEEPQRELPSARIRCPKGSKAYGSHCYALFLSPKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 MLPPMALPSVSWMLLSCLMLLSQVQGEEPQRELPSARIRCPKGSKAYGSHCYALFLSPKS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 WTDADLACQKRPSGNLVSVLSGAEGSFVSSLVKSIGNSYSYVWIGLHDPTQGTEPNGEGW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 WTDADLACQKRPSGNLVSVLSGAEGSFVSSLVKSIGNSYSYVWIGLHDPTQGTEPNGEGW 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 EWSSSDVMNYFAWERNPSTISSPGHCASLSRSTAFLRWKDYNCNVRLPYVCKFTD ::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS19 EWSSSDVMNYFAWERNPSTISSPGHCASLSRSTAFLRWKDYNCNVRLPYVCKFTD 130 140 150 160 170 >>CCDS1962.1 REG3G gene_id:130120|Hs108|chr2 (175 aa) initn: 1133 init1: 1094 opt: 1094 Z-score: 1342.7 bits: 254.9 E(32554): 1.8e-68 Smith-Waterman score: 1094; 85.1% identity (95.4% similar) in 175 aa overlap (1-175:1-175) 10 20 30 40 50 60 pF1KB6 MLPPMALPSVSWMLLSCLMLLSQVQGEEPQRELPSARIRCPKGSKAYGSHCYALFLSPKS ::::::::::::::::::.:: :::::: :.:::: :: :::::::::: :::::::::: CCDS19 MLPPMALPSVSWMLLSCLILLCQVQGEETQKELPSPRISCPKGSKAYGSPCYALFLSPKS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 WTDADLACQKRPSGNLVSVLSGAEGSFVSSLVKSIGNSYSYVWIGLHDPTQGTEPNGEGW : ::::::::::::.:::::::::::::::::.::.:::::.::::::::::.::.:.:: CCDS19 WMDADLACQKRPSGKLVSVLSGAEGSFVSSLVRSISNSYSYIWIGLHDPTQGSEPDGDGW 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 EWSSSDVMNYFAWERNPSTISSPGHCASLSRSTAFLRWKDYNCNVRLPYVCKFTD ::::.:::::::::.::::: .::::.::::::.::.::::::...::::::: : CCDS19 EWSSTDVMNYFAWEKNPSTILNPGHCGSLSRSTGFLKWKDYNCDAKLPYVCKFKD 130 140 150 160 170 >>CCDS1964.1 REG1A gene_id:5967|Hs108|chr2 (166 aa) initn: 578 init1: 417 opt: 588 Z-score: 725.5 bits: 140.6 E(32554): 4.3e-34 Smith-Waterman score: 588; 50.0% identity (76.2% similar) in 172 aa overlap (5-175:1-166) 10 20 30 40 50 60 pF1KB6 MLPPMALPSVSWMLLSCLMLLSQVQGEEPQRELPSARIRCPKGSKAYGSHCYALFLSPKS :: : .::.::::.::: ::.: : :::.::: ::.:..:: :.:: . . .. CCDS19 MAQTSSYFMLISCLMFLSQSQGQEAQTELPQARISCPEGTNAYRSYCYYFNEDRET 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 WTDADLACQKRPSGNLVSVLSGAEGSFVSSLVKSIGNSYSYVWIGLHDPTQGTEPNGEGW :.:::: ::. ::::::::. :::.::.::.: :.. :::::::: .. . : CCDS19 WVDADLYCQNMNSGNLVSVLTQAEGAFVASLIKESGTDDFNVWIGLHDPKKNRR-----W 60 70 80 90 100 110 130 140 150 160 170 pF1KB6 EWSSSDVMNYFAWERN-PSTISSPGHCASLSRSTAFLRWKDYNCNVRLPYVCKFTD .:::.....: .: . ::... ::.:.::. ::.: .::: :. .. .:::: . CCDS19 HWSSGSLVSYKSWGIGAPSSVN-PGYCVSLTSSTGFQKWKDVPCEDKFSFVCKFKN 120 130 140 150 160 >>CCDS1963.1 REG1B gene_id:5968|Hs108|chr2 (166 aa) initn: 556 init1: 397 opt: 564 Z-score: 696.2 bits: 135.2 E(32554): 1.9e-32 Smith-Waterman score: 564; 46.2% identity (74.9% similar) in 171 aa overlap (5-175:1-166) 10 20 30 40 50 60 pF1KB6 MLPPMALPSVSWMLLSCLMLLSQVQGEEPQRELPSARIRCPKGSKAYGSHCYALFLSPKS :: . .::.: ::.:: ::.: : :::. :: ::.:..:: :.:: . .:.. CCDS19 MAQTNSFFMLISSLMFLSLSQGQESQTELPNPRISCPEGTNAYRSYCYYFNEDPET 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 WTDADLACQKRPSGNLVSVLSGAEGSFVSSLVKSIGNSYSYVWIGLHDPTQGTEPNGEGW :.:::: ::. ::::::::. :::.::.::.: ... : :::::::: .. . : CCDS19 WVDADLYCQNMNSGNLVSVLTQAEGAFVASLIKESSTDDSNVWIGLHDPKKNRR-----W 60 70 80 90 100 110 130 140 150 160 170 pF1KB6 EWSSSDVMNYFAWERNPSTISSPGHCASLSRSTAFLRWKDYNCNVRLPYVCKFTD .:::.....: .:. . . .. :.::::. ..: .::: .:. .. .:::: . CCDS19 HWSSGSLVSYKSWDTGSPSSANAGYCASLTSCSGFKKWKDESCEKKFSFVCKFKN 120 130 140 150 160 >>CCDS58714.1 REG3G gene_id:130120|Hs108|chr2 (129 aa) initn: 808 init1: 401 opt: 403 Z-score: 501.1 bits: 98.8 E(32554): 1.4e-21 Smith-Waterman score: 708; 61.1% identity (69.1% similar) in 175 aa overlap (1-175:1-129) 10 20 30 40 50 60 pF1KB6 MLPPMALPSVSWMLLSCLMLLSQVQGEEPQRELPSARIRCPKGSKAYGSHCYALFLSPKS ::::::::::::::::::.:: :::::: :.:::: :: :::::::::: :::::::::: CCDS58 MLPPMALPSVSWMLLSCLILLCQVQGEETQKELPSPRISCPKGSKAYGSPCYALFLSPKS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 WTDADLACQKRPSGNLVSVLSGAEGSFVSSLVKSIGNSYSYVWIGLHDPTQGTEPNGEGW : ::: :.::.:.:: CCDS58 WMDAD----------------------------------------------GSEPDGDGW 70 130 140 150 160 170 pF1KB6 EWSSSDVMNYFAWERNPSTISSPGHCASLSRSTAFLRWKDYNCNVRLPYVCKFTD ::::.:::::::::.::::: .::::.::::::.::.::::::...::::::: : CCDS58 EWSSTDVMNYFAWEKNPSTILNPGHCGSLSRSTGFLKWKDYNCDAKLPYVCKFKD 80 90 100 110 120 >>CCDS906.1 REG4 gene_id:83998|Hs108|chr1 (158 aa) initn: 254 init1: 125 opt: 310 Z-score: 386.5 bits: 77.9 E(32554): 3.3e-15 Smith-Waterman score: 310; 32.7% identity (61.7% similar) in 162 aa overlap (13-173:10-156) 10 20 30 40 50 60 pF1KB6 MLPPMALPSVSWMLLSCLMLLSQVQGEEPQRELPSARIRCPKGSKAYGSHCYALFLSPKS .::::: . : :. .: :: : : . :.::. : . .. CCDS90 MASRSMRLLLLLSCLAK-TGVLGDIIMR--PS----CAPGWFYHKSNCYGYFRKLRN 10 20 30 40 50 70 80 90 100 110 pF1KB6 WTDADLACQKRPSG-NLVSVLSGAEGSFVSSLVKSIGNSYSYVWIGLHDPTQGTEPNGEG :.::.: ::. .: .:.:.:: :.: .. ... : .::::::: . . CCDS90 WSDAELECQSYGNGAHLASILSLKEASTIAEYISGYQRSQP-IWIGLHDPQKRQQ----- 60 70 80 90 100 120 130 140 150 160 170 pF1KB6 WEWSSSDVMNYFAWERNPSTISSPGHCASLSRSTAFLRWKDYNCNVRLPYVCKFTD :.: .. .. : .: . ..... ::: .: .. :: :.. .:: : ..::. CCDS90 WQWIDGAMYLYRSW--SGKSMGGNKHCAEMSSNNNFLTWSSNECNKRQHFLCKYRP 110 120 130 140 150 >>CCDS81953.1 CLEC19A gene_id:728276|Hs108|chr16 (186 aa) initn: 226 init1: 97 opt: 257 Z-score: 320.9 bits: 66.0 E(32554): 1.5e-11 Smith-Waterman score: 257; 34.0% identity (62.8% similar) in 156 aa overlap (29-172:32-179) 10 20 30 40 50 pF1KB6 MLPPMALPSVSWMLLSCLMLLSQVQGEEPQRELPSARIRCPKGSKAYGSHCYALFLSP :. ::: :: . .::: .: CCDS81 QRWTLWAAAFLTLHSAQAFPQTDISISPALPELPLPSL---CPLFWMEFKGHCYRFFPLN 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 KSWTDADLACQK----RPSGNLVSVLSGAEGSFVSSLVKS-IGNSYSYVWIGLHDPTQGT :.:..::: :.. : :..:.:. : :. :: .::.: . . . :: :::: : CCDS81 KTWAEADLYCSEFSVGRKSAKLASIHSWEENVFVYDLVNSCVPGIPADVWTGLHDHRQ-- 60 70 80 90 100 110 120 130 140 150 160 pF1KB6 EPNGEGWEWSSSDVMNYFAWE-RNPS--TISSPGH--CASL-SRSTAFLR-WKDYNCNVR .:. .::.... ..: :. .:. . ..: . :... : :. :: :.: .:. . CCDS81 --EGQ-FEWTDGSSYDYSYWDGSQPDDGVHADPEEEDCVQIWYRPTSALRSWNDNTCSRK 120 130 140 150 160 170 170 pF1KB6 LPYVCKFTD .:.::: CCDS81 FPFVCKIPSLTIH 180 175 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 00:28:31 2016 done: Sat Nov 5 00:28:32 2016 Total Scan time: 1.730 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]