FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6849, 177 aa 1>>>pF1KB6849 177 - 177 aa - 177 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6119+/-0.000389; mu= 10.9357+/- 0.024 mean_var=60.8350+/-12.134, 0's: 0 Z-trim(111.5): 22 B-trim: 0 in 0/53 Lambda= 0.164436 statistics sampled from 20070 (20091) to 20070 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.622), E-opt: 0.2 (0.236), width: 16 Scan time: 5.150 The best scores are: opt bits E(85289) NP_001035532 (OMIM: 600422) gastrotropin isoform 1 ( 177) 1146 280.2 1.2e-75 NP_001124430 (OMIM: 600422) gastrotropin isoform 1 ( 177) 1146 280.2 1.2e-75 NP_001436 (OMIM: 600422) gastrotropin isoform 2 [H ( 128) 827 204.5 5.2e-53 NP_001434 (OMIM: 134650) fatty acid-binding protei ( 127) 337 88.3 5.1e-18 NP_000125 (OMIM: 134640) fatty acid-binding protei ( 132) 169 48.4 5.3e-06 NP_004093 (OMIM: 134651) fatty acid-binding protei ( 133) 155 45.1 5.3e-05 XP_011539309 (OMIM: 134651) PREDICTED: fatty acid- ( 126) 148 43.4 0.00016 NP_001433 (OMIM: 600434) fatty acid-binding protei ( 132) 134 40.1 0.0017 NP_004155 (OMIM: 180280) retinol-binding protein 2 ( 134) 130 39.2 0.0033 NP_001869 (OMIM: 180231) cellular retinoic acid-bi ( 138) 126 38.2 0.0065 XP_016855832 (OMIM: 180231) PREDICTED: cellular re ( 138) 126 38.2 0.0065 NP_001186652 (OMIM: 180231) cellular retinoic acid ( 138) 126 38.2 0.0065 NP_001437 (OMIM: 602965) fatty acid-binding protei ( 132) 125 38.0 0.0073 >>NP_001035532 (OMIM: 600422) gastrotropin isoform 1 [Ho (177 aa) initn: 1146 init1: 1146 opt: 1146 Z-score: 1479.3 bits: 280.2 E(85289): 1.2e-75 Smith-Waterman score: 1146; 100.0% identity (100.0% similar) in 177 aa overlap (1-177:1-177) 10 20 30 40 50 60 pF1KB6 MKTVTMMMVVEMQALTQVLRAVLSACTWVSRKGDLQRMKQTHKGKPPSSMAFTGKFEMES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKTVTMMMVVEMQALTQVLRAVLSACTWVSRKGDLQRMKQTHKGKPPSSMAFTGKFEMES 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 EKNYDEFMKLLGISSDVIEKARNFKIVTEVQQDGQDFTWSQHYSGGHTMTNKFTVGKESN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKNYDEFMKLLGISSDVIEKARNFKIVTEVQQDGQDFTWSQHYSGGHTMTNKFTVGKESN 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 IQTMGGKTFKATVQMEGGKLVVNFPNYHQTSEIVGDKLVEVSTIGGVTYERVSKRLA ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQTMGGKTFKATVQMEGGKLVVNFPNYHQTSEIVGDKLVEVSTIGGVTYERVSKRLA 130 140 150 160 170 >>NP_001124430 (OMIM: 600422) gastrotropin isoform 1 [Ho (177 aa) initn: 1146 init1: 1146 opt: 1146 Z-score: 1479.3 bits: 280.2 E(85289): 1.2e-75 Smith-Waterman score: 1146; 100.0% identity (100.0% similar) in 177 aa overlap (1-177:1-177) 10 20 30 40 50 60 pF1KB6 MKTVTMMMVVEMQALTQVLRAVLSACTWVSRKGDLQRMKQTHKGKPPSSMAFTGKFEMES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKTVTMMMVVEMQALTQVLRAVLSACTWVSRKGDLQRMKQTHKGKPPSSMAFTGKFEMES 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 EKNYDEFMKLLGISSDVIEKARNFKIVTEVQQDGQDFTWSQHYSGGHTMTNKFTVGKESN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKNYDEFMKLLGISSDVIEKARNFKIVTEVQQDGQDFTWSQHYSGGHTMTNKFTVGKESN 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 IQTMGGKTFKATVQMEGGKLVVNFPNYHQTSEIVGDKLVEVSTIGGVTYERVSKRLA ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IQTMGGKTFKATVQMEGGKLVVNFPNYHQTSEIVGDKLVEVSTIGGVTYERVSKRLA 130 140 150 160 170 >>NP_001436 (OMIM: 600422) gastrotropin isoform 2 [Homo (128 aa) initn: 827 init1: 827 opt: 827 Z-score: 1072.6 bits: 204.5 E(85289): 5.2e-53 Smith-Waterman score: 827; 100.0% identity (100.0% similar) in 128 aa overlap (50-177:1-128) 20 30 40 50 60 70 pF1KB6 RAVLSACTWVSRKGDLQRMKQTHKGKPPSSMAFTGKFEMESEKNYDEFMKLLGISSDVIE :::::::::::::::::::::::::::::: NP_001 MAFTGKFEMESEKNYDEFMKLLGISSDVIE 10 20 30 80 90 100 110 120 130 pF1KB6 KARNFKIVTEVQQDGQDFTWSQHYSGGHTMTNKFTVGKESNIQTMGGKTFKATVQMEGGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KARNFKIVTEVQQDGQDFTWSQHYSGGHTMTNKFTVGKESNIQTMGGKTFKATVQMEGGK 40 50 60 70 80 90 140 150 160 170 pF1KB6 LVVNFPNYHQTSEIVGDKLVEVSTIGGVTYERVSKRLA :::::::::::::::::::::::::::::::::::::: NP_001 LVVNFPNYHQTSEIVGDKLVEVSTIGGVTYERVSKRLA 100 110 120 >>NP_001434 (OMIM: 134650) fatty acid-binding protein, l (127 aa) initn: 322 init1: 139 opt: 337 Z-score: 444.5 bits: 88.3 E(85289): 5.1e-18 Smith-Waterman score: 337; 36.7% identity (82.0% similar) in 128 aa overlap (50-176:1-127) 20 30 40 50 60 70 pF1KB6 RAVLSACTWVSRKGDLQRMKQTHKGKPPSSMAFTGKFEMESEKNYDEFMKLLGISSDVIE :.:.::....:..:.. ::: .:. ..:. NP_001 MSFSGKYQLQSQENFEAFMKAIGLPEELIQ 10 20 30 80 90 100 110 120 130 pF1KB6 KARNFKIVTEVQQDGQDFTWSQHYSGGHTMTNKFTVGKESNIQTMGGKTFKATVQMEG-G :....: :.:. :.:. : .. .:.... :.::::.: ...:: :. :..::.:: . NP_001 KGKDIKGVSEIVQNGKHFKFTIT-AGSKVIQNEFTVGEECELETMTGEKVKTVVQLEGDN 40 50 60 70 80 140 150 160 170 pF1KB6 KLVVNFPNYHQTSEIVGDKLVEVSTIGGVTYERVSKRLA :::..: : ....:. :: .... :.: ....:.:::. NP_001 KLVTTFKNIKSVTELNGDIITNTMTLGDIVFKRISKRI 90 100 110 120 >>NP_000125 (OMIM: 134640) fatty acid-binding protein, i (132 aa) initn: 181 init1: 87 opt: 169 Z-score: 228.8 bits: 48.4 E(85289): 5.3e-06 Smith-Waterman score: 169; 26.1% identity (61.2% similar) in 134 aa overlap (50-175:1-131) 20 30 40 50 60 70 pF1KB6 RAVLSACTWVSRKGDLQRMKQTHKGKPPSSMAFTGKFEMESEKNYDEFMKLLGISSDVIE ::: . .... .:::.::. .:. .... NP_000 MAFDSTWKVDRSENYDKFMEKMGV--NIVK 10 20 80 90 100 110 120 130 pF1KB6 K--ARNFKIVTEVQQDGQDFTWSQHYSGGHTMTNKFTVGKESNIQTMGGKTFKATVQMEG . : . .. . :.:. :: .. : ... : .: : . : ...: ..:: NP_000 RKLAAHDNLKLTITQEGNKFT-VKESSTFRNIEVVFELGVTFNYNLADGTELRGTWSLEG 30 40 50 60 70 80 140 150 160 170 pF1KB6 GKLVVNFP------NYHQTSEIVGDKLVEVSTIGGVTYERVSKRLA .::. .: . . . ::.::.::.. . :: .:. :. NP_000 NKLIGKFKRTDNGNELNTVREIIGDELVQTYVYEGVEAKRIFKKD 90 100 110 120 130 >>NP_004093 (OMIM: 134651) fatty acid-binding protein, h (133 aa) initn: 142 init1: 78 opt: 155 Z-score: 210.8 bits: 45.1 E(85289): 5.3e-05 Smith-Waterman score: 155; 27.5% identity (60.3% similar) in 131 aa overlap (51-177:4-133) 30 40 50 60 70 80 pF1KB6 AVLSACTWVSRKGDLQRMKQTHKGKPPSSMAFTGKFEMESEKNYDEFMKLLGISSDVIEK :: : ... . ::.:..:: ::.. . . NP_004 MVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQV 10 20 30 90 100 110 120 130 140 pF1KB6 ARNFKIVTEVQQDGQDFTWSQHYSGGHTMTNKFTVGKESNIQTMGGKTFKATVQMEGGKL : : .: ....:. .: . : . .: . : .: : . : . :. : ..:::: NP_004 ASMTKPTTIIEKNGDILTLKTHSTFKNTEIS-FKLGVEFDETTADDRKVKSIVTLDGGKL 40 50 60 70 80 90 150 160 170 pF1KB6 V-VNFPNYHQTS---EIVGDKLVEVSTIGGVTYERVSKRLA : .. . ..:. :.. ::. . : : .. :. .. : NP_004 VHLQKWDGQETTLVRELIDGKLILTLTHGTAVCTRTYEKEA 100 110 120 130 >>XP_011539309 (OMIM: 134651) PREDICTED: fatty acid-bind (126 aa) initn: 141 init1: 78 opt: 148 Z-score: 202.2 bits: 43.4 E(85289): 0.00016 Smith-Waterman score: 148; 30.8% identity (61.5% similar) in 91 aa overlap (51-141:4-93) 30 40 50 60 70 80 pF1KB6 AVLSACTWVSRKGDLQRMKQTHKGKPPSSMAFTGKFEMESEKNYDEFMKLLGISSDVIEK :: : ... . ::.:..:: ::.. . . XP_011 MVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQV 10 20 30 90 100 110 120 130 140 pF1KB6 ARNFKIVTEVQQDGQDFTWSQHYSGGHTMTNKFTVGKESNIQTMGGKTFKATVQMEGGKL : : .: ....:. .: . : . .: . : .: : . : . :. : ..:::: XP_011 ASMTKPTTIIEKNGDILTLKTHSTFKNTEIS-FKLGVEFDETTADDRKVKSIVTLDGGKL 40 50 60 70 80 90 150 160 170 pF1KB6 VVNFPNYHQTSEIVGDKLVEVSTIGGVTYERVSKRLA : XP_011 VHLQKWDGQETTLVRELIDGKLILMEKLQLRNVK 100 110 120 >>NP_001433 (OMIM: 600434) fatty acid-binding protein, a (132 aa) initn: 82 init1: 50 opt: 134 Z-score: 183.9 bits: 40.1 E(85289): 0.0017 Smith-Waterman score: 134; 26.2% identity (57.7% similar) in 130 aa overlap (51-175:4-131) 30 40 50 60 70 80 pF1KB6 AVLSACTWVSRKGDLQRMKQTHKGKPPSSMAFTGKFEMESEKNYDEFMKLLGISSDVIEK ::.: ... : .:.:..:: .:.. . . NP_001 MCDAFVGTWKLVSSENFDDYMKEVGVGFATRKV 10 20 30 90 100 110 120 130 140 pF1KB6 ARNFKIVTEVQQDGQDFTWSQHYSGGHTMTNKFTVGKESNIQTMGGKTFKATVQMEGGKL : : .. .:. .: ... . .: . : .:.: . : . :.:. ..:: . NP_001 AGMAKPNMIISVNGDVITIKSESTFKNTEIS-FILGQEFDEVTADDRKVKSTITLDGG-V 40 50 60 70 80 90 150 160 170 pF1KB6 VVNFPNYHQTSEIV-----GDKLVEVSTIGGVTYERVSKRLA .:. .. : . :::: .. ::: :: .: NP_001 LVHVQKWDGKSTTIKRKREDDKLVVECVMKGVTSTRVYERA 100 110 120 130 >>NP_004155 (OMIM: 180280) retinol-binding protein 2 [Ho (134 aa) initn: 134 init1: 79 opt: 130 Z-score: 178.7 bits: 39.2 E(85289): 0.0033 Smith-Waterman score: 130; 29.7% identity (54.7% similar) in 128 aa overlap (54-175:7-133) 30 40 50 60 70 80 pF1KB6 SACTWVSRKGDLQRMKQTHKGKPPSSMAFTGKFEMESEKNYDEFMKLLGISSDVIEKARN : .::::..:.. .:: : :. . . : NP_004 MTRDQNGTWEMESNENFEGYMKALDIDFATRKIAVR 10 20 30 90 100 110 120 130 140 pF1KB6 FKIVTEVQQDGQDFTWSQHYSGGHTMTNKFTVGKESN--IQTMGGKTFKATVQMEGGKLV . . ..:::..: .. : ... :::: : . ... .. :: : :: :: NP_004 LTQTKVIDQDGDNFK-TKTTSTFRNYDVDFTVGVEFDEYTKSLDNRHVKALVTWEGDVLV 40 50 60 70 80 90 150 160 170 pF1KB6 V----NFPNYHQTSEIVGDKLVEVSTIGGVTYERVSKRLA . : . : :::: : : . ..: :. NP_004 CVQKGEKENRGWKQWIEGDKLYLELTCGDQVCRQVFKKK 100 110 120 130 >>NP_001869 (OMIM: 180231) cellular retinoic acid-bindin (138 aa) initn: 51 init1: 51 opt: 126 Z-score: 173.3 bits: 38.2 E(85289): 0.0065 Smith-Waterman score: 133; 27.4% identity (59.3% similar) in 135 aa overlap (52-175:4-137) 30 40 50 60 70 pF1KB6 VLSACTWVSRKGDLQRMKQTHKGKPPSSMAFTGKFEMESEKNYDEFMKLLGISSDV--IE :.:.... .:..:..:.::.. . : NP_001 MPNFSGNWKIIRSENFEELLKVLGVNVMLRKIA 10 20 30 80 90 100 110 120 130 pF1KB6 KARNFKIVTEVQQDGQDFTWSQHYSGGHTMTNKFTVGKESNIQTMGGKTFKATVQMEG-G : : ..:..:.:. : . . . .: .: ::.: . ::. :. :. :. :. . NP_001 VAAASKPAVEIKQEGDTF-YIKTSTTVRTTEINFKVGEEFEEQTVDGRPCKSLVKWESEN 40 50 60 70 80 90 140 150 160 170 pF1KB6 KLVVNF-------PNYHQTSEIVGD-KLVEVSTIGGVTYERVSKRLA :.: . :. : :...: .:. . : :. :: : NP_001 KMVCEQKLLKGEGPKTSWTRELTNDGELILTMTADDVVCTRVYVRE 100 110 120 130 177 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 15:03:39 2016 done: Fri Nov 4 15:03:40 2016 Total Scan time: 5.150 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]