Result of FASTA (omim) for
pF1KB6851
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6851, 133 aa
1>>>pF1KB6851 133 - 133 aa - 133 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3118+/-0.000288; mu= 10.8490+/- 0.018
mean_var=58.7980+/-11.437, 0's: 0 Z-trim(117.9): 9 B-trim: 86 in 2/52
Lambda= 0.167260
statistics sampled from 30228 (30237) to 30228 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.757), E-opt: 0.2 (0.355), width: 16
Scan time: 4.880
The best scores are: opt bits E(85289)
NP_001186815 (OMIM: 146660) interleukin-7 isoform ( 133) 892 222.8 1.3e-58
NP_001186817 (OMIM: 146660) interleukin-7 isoform ( 115) 522 133.5 8.5e-32
XP_011515825 (OMIM: 146660) PREDICTED: interleukin ( 142) 516 132.1 2.8e-31
NP_001186816 (OMIM: 146660) interleukin-7 isoform ( 159) 516 132.1 3.1e-31
XP_011515824 (OMIM: 146660) PREDICTED: interleukin ( 167) 516 132.1 3.2e-31
NP_000871 (OMIM: 146660) interleukin-7 isoform 1 p ( 177) 516 132.1 3.4e-31
XP_016868886 (OMIM: 146660) PREDICTED: interleukin ( 126) 379 99.0 2.3e-21
>>NP_001186815 (OMIM: 146660) interleukin-7 isoform 2 pr (133 aa)
initn: 892 init1: 892 opt: 892 Z-score: 1173.3 bits: 222.8 E(85289): 1.3e-58
Smith-Waterman score: 892; 100.0% identity (100.0% similar) in 133 aa overlap (1-133:1-133)
10 20 30 40 50 60
pF1KB6 MFHVSFRYIFGLPPLILVLLPVASSDCDIEGKDGKQYESVLMVSIDQLLDSMKEIGSNCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFHVSFRYIFGLPPLILVLLPVASSDCDIEGKDGKQYESVLMVSIDQLLDSMKEIGSNCL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 NNEFNFFKRHICDANKVKGRKPAALGEAQPTKSLEENKSLKEQKKLNDLCFLKRLLQEIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNEFNFFKRHICDANKVKGRKPAALGEAQPTKSLEENKSLKEQKKLNDLCFLKRLLQEIK
70 80 90 100 110 120
130
pF1KB6 TCWNKILMGTKEH
:::::::::::::
NP_001 TCWNKILMGTKEH
130
>>NP_001186817 (OMIM: 146660) interleukin-7 isoform 4 pr (115 aa)
initn: 550 init1: 517 opt: 522 Z-score: 691.8 bits: 133.5 E(85289): 8.5e-32
Smith-Waterman score: 732; 86.5% identity (86.5% similar) in 133 aa overlap (1-133:1-115)
10 20 30 40 50 60
pF1KB6 MFHVSFRYIFGLPPLILVLLPVASSDCDIEGKDGKQYESVLMVSIDQLLDSMKEIGSNCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFHVSFRYIFGLPPLILVLLPVASSDCDIEGKDGKQYESVLMVSIDQLLDSMKEIGSNCL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 NNEFNFFKRHICDANKVKGRKPAALGEAQPTKSLEENKSLKEQKKLNDLCFLKRLLQEIK
:::::::::::::::: ::::::::::::::::::::::::::
NP_001 NNEFNFFKRHICDANK------------------EENKSLKEQKKLNDLCFLKRLLQEIK
70 80 90 100
130
pF1KB6 TCWNKILMGTKEH
:::::::::::::
NP_001 TCWNKILMGTKEH
110
>>XP_011515825 (OMIM: 146660) PREDICTED: interleukin-7 i (142 aa)
initn: 516 init1: 516 opt: 516 Z-score: 682.5 bits: 132.1 E(85289): 2.8e-31
Smith-Waterman score: 532; 68.1% identity (68.1% similar) in 138 aa overlap (1-94:1-138)
10 20 30 40 50 60
pF1KB6 MFHVSFRYIFGLPPLILVLLPVASSDCDIEGKDGKQYESVLMVSIDQLLDSMKEIGSNCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MFHVSFRYIFGLPPLILVLLPVASSDCDIEGKDGKQYESVLMVSIDQLLDSMKEIGSNCL
10 20 30 40 50 60
70
pF1KB6 NNEFNFFKRHICDANK--------------------------------------------
::::::::::::::::
XP_011 NNEFNFFKRHICDANKEGMFLFRAARKLRQFLKMNSTGDFDLHLLKVSEGTTILLNCTGQ
70 80 90 100 110 120
80 90 100 110 120 130
pF1KB6 VKGRKPAALGEAQPTKSLEENKSLKEQKKLNDLCFLKRLLQEIKTCWNKILMGTKEH
::::::::::::::::::
XP_011 VKGRKPAALGEAQPTKSLSLVK
130 140
>>NP_001186816 (OMIM: 146660) interleukin-7 isoform 3 pr (159 aa)
initn: 764 init1: 516 opt: 516 Z-score: 681.8 bits: 132.1 E(85289): 3.1e-31
Smith-Waterman score: 711; 76.1% identity (78.6% similar) in 159 aa overlap (1-133:1-159)
10 20 30 40 50 60
pF1KB6 MFHVSFRYIFGLPPLILVLLPVASSDCDIEGKDGKQYESVLMVSIDQLLDSMKEIGSNCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFHVSFRYIFGLPPLILVLLPVASSDCDIEGKDGKQYESVLMVSIDQLLDSMKEIGSNCL
10 20 30 40 50 60
70 80 90
pF1KB6 NNEFNFFKRHICDANKV---------KGR---KPAALGE--------AQPTKSL------
:::::::::::::::: : : : . :. .. : :
NP_001 NNEFNFFKRHICDANKEGMFLFRAARKLRQFLKMNSTGDFDLHLLKVSEGTTILLNCTGQ
70 80 90 100 110 120
100 110 120 130
pF1KB6 EENKSLKEQKKLNDLCFLKRLLQEIKTCWNKILMGTKEH
:::::::::::::::::::::::::::::::::::::::
NP_001 EENKSLKEQKKLNDLCFLKRLLQEIKTCWNKILMGTKEH
130 140 150
>>XP_011515824 (OMIM: 146660) PREDICTED: interleukin-7 i (167 aa)
initn: 516 init1: 516 opt: 516 Z-score: 681.4 bits: 132.1 E(85289): 3.2e-31
Smith-Waterman score: 534; 65.3% identity (68.7% similar) in 147 aa overlap (1-103:1-145)
10 20 30 40 50 60
pF1KB6 MFHVSFRYIFGLPPLILVLLPVASSDCDIEGKDGKQYESVLMVSIDQLLDSMKEIGSNCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MFHVSFRYIFGLPPLILVLLPVASSDCDIEGKDGKQYESVLMVSIDQLLDSMKEIGSNCL
10 20 30 40 50 60
70
pF1KB6 NNEFNFFKRHICDANK--------------------------------------------
::::::::::::::::
XP_011 NNEFNFFKRHICDANKEGMFLFRAARKLRQFLKMNSTGDFDLHLLKVSEGTTILLNCTGQ
70 80 90 100 110 120
80 90 100 110 120 130
pF1KB6 VKGRKPAALGEAQPTKSLEENKSLKEQKKLNDLCFLKRLLQEIKTCWNKILMGTKEH
:::::::::::::::::: ...:..:
XP_011 VKGRKPAALGEAQPTKSL--SSGLQKQFTFYRSNGRHTHSFHCKLSFLH
130 140 150 160
>>NP_000871 (OMIM: 146660) interleukin-7 isoform 1 precu (177 aa)
initn: 560 init1: 516 opt: 516 Z-score: 681.0 bits: 132.1 E(85289): 3.4e-31
Smith-Waterman score: 701; 73.3% identity (73.3% similar) in 165 aa overlap (1-121:1-165)
10 20 30 40 50 60
pF1KB6 MFHVSFRYIFGLPPLILVLLPVASSDCDIEGKDGKQYESVLMVSIDQLLDSMKEIGSNCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MFHVSFRYIFGLPPLILVLLPVASSDCDIEGKDGKQYESVLMVSIDQLLDSMKEIGSNCL
10 20 30 40 50 60
70
pF1KB6 NNEFNFFKRHICDANK--------------------------------------------
::::::::::::::::
NP_000 NNEFNFFKRHICDANKEGMFLFRAARKLRQFLKMNSTGDFDLHLLKVSEGTTILLNCTGQ
70 80 90 100 110 120
80 90 100 110 120 130
pF1KB6 VKGRKPAALGEAQPTKSLEENKSLKEQKKLNDLCFLKRLLQEIKTCWNKILMGTKEH
:::::::::::::::::::::::::::::::::::::::::::::
NP_000 VKGRKPAALGEAQPTKSLEENKSLKEQKKLNDLCFLKRLLQEIKTCWNKILMGTKEH
130 140 150 160 170
>>XP_016868886 (OMIM: 146660) PREDICTED: interleukin-7 i (126 aa)
initn: 378 init1: 378 opt: 379 Z-score: 504.7 bits: 99.0 E(85289): 2.3e-21
Smith-Waterman score: 458; 65.1% identity (65.1% similar) in 126 aa overlap (52-133:1-126)
30 40 50 60 70
pF1KB6 VASSDCDIEGKDGKQYESVLMVSIDQLLDSMKEIGSNCLNNEFNFFKRHICDANK-----
:::::::::::::::::::::::::
XP_016 MKEIGSNCLNNEFNFFKRHICDANKEGMFL
10 20 30
80 90
pF1KB6 ---------------------------------------VKGRKPAALGEAQPTKSLEEN
:::::::::::::::::::::
XP_016 FRAARKLRQFLKMNSTGDFDLHLLKVSEGTTILLNCTGQVKGRKPAALGEAQPTKSLEEN
40 50 60 70 80 90
100 110 120 130
pF1KB6 KSLKEQKKLNDLCFLKRLLQEIKTCWNKILMGTKEH
::::::::::::::::::::::::::::::::::::
XP_016 KSLKEQKKLNDLCFLKRLLQEIKTCWNKILMGTKEH
100 110 120
133 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 20:27:52 2016 done: Sat Nov 5 20:27:52 2016
Total Scan time: 4.880 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]