FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6852, 194 aa 1>>>pF1KB6852 194 - 194 aa - 194 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.3748+/-0.000897; mu= 6.9190+/- 0.055 mean_var=164.0720+/-32.275, 0's: 0 Z-trim(112.5): 47 B-trim: 0 in 0/55 Lambda= 0.100128 statistics sampled from 13187 (13233) to 13187 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.73), E-opt: 0.2 (0.406), width: 16 Scan time: 2.180 The best scores are: opt bits E(32554) CCDS2390.1 MYL1 gene_id:4632|Hs108|chr2 ( 194) 1248 191.0 3.9e-49 CCDS2391.1 MYL1 gene_id:4632|Hs108|chr2 ( 150) 919 143.4 6.5e-35 CCDS11510.1 MYL4 gene_id:4635|Hs108|chr17 ( 197) 905 141.5 3.3e-34 CCDS2746.1 MYL3 gene_id:4634|Hs108|chr3 ( 195) 890 139.3 1.4e-33 CCDS8905.1 MYL6B gene_id:140465|Hs108|chr12 ( 208) 838 131.8 2.8e-31 CCDS8906.1 MYL6 gene_id:4637|Hs108|chr12 ( 151) 754 119.5 9.8e-28 CCDS31834.1 MYL6 gene_id:4637|Hs108|chr12 ( 151) 725 115.4 1.8e-26 CCDS7069.1 CALML3 gene_id:810|Hs108|chr10 ( 149) 404 69.0 1.6e-12 CCDS9892.1 CALM1 gene_id:801|Hs108|chr14 ( 149) 395 67.7 4e-12 CCDS1832.1 CALM2 gene_id:805|Hs108|chr2 ( 149) 395 67.7 4e-12 CCDS33061.1 CALM3 gene_id:808|Hs108|chr19 ( 149) 395 67.7 4e-12 >>CCDS2390.1 MYL1 gene_id:4632|Hs108|chr2 (194 aa) initn: 1248 init1: 1248 opt: 1248 Z-score: 995.6 bits: 191.0 E(32554): 3.9e-49 Smith-Waterman score: 1248; 100.0% identity (100.0% similar) in 194 aa overlap (1-194:1-194) 10 20 30 40 50 60 pF1KB6 MAPKKDVKKPVAAAAAAPAPAPAPAPAPAPAKPKEEKIDLSAIKIEFSKEQQDEFKEAFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 MAPKKDVKKPVAAAAAAPAPAPAPAPAPAPAKPKEEKIDLSAIKIEFSKEQQDEFKEAFL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LFDRTGDSKITLSQVGDVLRALGTNPTNAEVRKVLGNPSNEELNAKKIEFEQFLPMMQAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 LFDRTGDSKITLSQVGDVLRALGTNPTNAEVRKVLGNPSNEELNAKKIEFEQFLPMMQAI 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 SNNKDQATYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMAGQEDSNG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 SNNKDQATYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMAGQEDSNG 130 140 150 160 170 180 190 pF1KB6 CINYEAFVKHIMSI :::::::::::::: CCDS23 CINYEAFVKHIMSI 190 >>CCDS2391.1 MYL1 gene_id:4632|Hs108|chr2 (150 aa) initn: 919 init1: 919 opt: 919 Z-score: 740.2 bits: 143.4 E(32554): 6.5e-35 Smith-Waterman score: 919; 96.0% identity (97.3% similar) in 150 aa overlap (45-194:1-150) 20 30 40 50 60 70 pF1KB6 AAAPAPAPAPAPAPAPAKPKEEKIDLSAIKIEFSKEQQDEFKEAFLLFDRTGDSKITLSQ . :: .: ::::::::::::::::::::: CCDS23 MSFSADQIAEFKEAFLLFDRTGDSKITLSQ 10 20 30 80 90 100 110 120 130 pF1KB6 VGDVLRALGTNPTNAEVRKVLGNPSNEELNAKKIEFEQFLPMMQAISNNKDQATYEDFVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 VGDVLRALGTNPTNAEVRKVLGNPSNEELNAKKIEFEQFLPMMQAISNNKDQATYEDFVE 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB6 GLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMAGQEDSNGCINYEAFVKHIMSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 GLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMAGQEDSNGCINYEAFVKHIMSI 100 110 120 130 140 150 >>CCDS11510.1 MYL4 gene_id:4635|Hs108|chr17 (197 aa) initn: 721 init1: 721 opt: 905 Z-score: 727.7 bits: 141.5 E(32554): 3.3e-34 Smith-Waterman score: 905; 71.9% identity (85.2% similar) in 196 aa overlap (1-193:1-196) 10 20 30 40 50 pF1KB6 MAPKK-DVKKPVAAAAAAPAPAPAPAPAPAPAKPKEEKIDLSAIKIEFSKEQQDEFKEAF ::::: . :: .: : :::::::::::::: ::: .: ...::.:. .: .:::::: CCDS11 MAPKKPEPKKEAAKPAPAPAPAPAPAPAPAPEAPKEPAFDPKSVKIDFTADQIEEFKEAF 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 LLFDRT--GDSKITLSQVGDVLRALGTNPTNAEVRKVLGNPSNEELNAKKIEFEQFLPMM ::::: :. ::: .: :::::::: ::::::: .:::.:. ::.:.: ..:: :::.. CCDS11 SLFDRTPTGEMKITYGQCGDVLRALGQNPTNAEVLRVLGKPKPEEMNVKMLDFETFLPIL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 QAISNNKDQATYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMAGQED : :: ::.:.:::::::::::::::.:::::::::::::::::::: : ::: :.::::: CCDS11 QHISRNKEQGTYEDFVEGLRVFDKESNGTVMGAELRHVLATLGEKMTEAEVEQLLAGQED 130 140 150 160 170 180 180 190 pF1KB6 SNGCINYEAFVKHIMSI .::::::::::::::: CCDS11 ANGCINYEAFVKHIMSG 190 >>CCDS2746.1 MYL3 gene_id:4634|Hs108|chr3 (195 aa) initn: 706 init1: 706 opt: 890 Z-score: 716.1 bits: 139.3 E(32554): 1.4e-33 Smith-Waterman score: 890; 72.3% identity (83.1% similar) in 195 aa overlap (1-193:1-194) 10 20 30 40 50 60 pF1KB6 MAPKKDVKKPVAAAAAAPAPAPAPAPAPAPAKPKEEKIDLSAIKIEFSKEQQDEFKEAFL ::::: : : ::: :::::: : : .::: ..: : :::::. :: .::::::. CCDS27 MAPKKPEPKK-DDAKAAPKAAPAPAPPPEPERPKEVEFDASKIKIEFTPEQIEEFKEAFM 10 20 30 40 50 70 80 90 100 110 pF1KB6 LFDRTG--DSKITLSQVGDVLRALGTNPTNAEVRKVLGNPSNEELNAKKIEFEQFLPMMQ ::::: . ::: .: :::::::: :::.::: .:::.: .::::.: ..:: ::::.: CCDS27 LFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQ 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 AISNNKDQATYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMAGQEDS ::.::: .::::::::::::::::::::::::::::::::::.. :.::: :::::::: CCDS27 HISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDS 120 130 140 150 160 170 180 190 pF1KB6 NGCINYEAFVKHIMSI ::::::::::::::: CCDS27 NGCINYEAFVKHIMSS 180 190 >>CCDS8905.1 MYL6B gene_id:140465|Hs108|chr12 (208 aa) initn: 1018 init1: 827 opt: 838 Z-score: 675.1 bits: 131.8 E(32554): 2.8e-31 Smith-Waterman score: 853; 62.5% identity (81.2% similar) in 208 aa overlap (1-194:1-208) 10 20 30 40 pF1KB6 MAPKKDV--KKPVAAAAAAPAPAPAPAPAP------------APAKPKEEKIDLSAIKIE : ::::: :::.. . . :: :: : :: :: : .: .::: . :: CCDS89 MPPKKDVPVKKPAGPSISKPAAKPAAAGAPPAKTKAEPAVPQAPQKTQEPPVDLSKVVIE 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB6 FSKEQQDEFKEAFLLFDRTGDSKITLSQVGDVLRALGTNPTNAEVRKVLGNPSNEELNAK :.:.: .:::::: ::::.::.:: :: :::.:::: ::::::: ::::::...::... CCDS89 FNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKSR 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB6 KIEFEQFLPMMQAISNNKDQATYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEE ...:: ::::.::...:. :.::::..::.::::::::: ::::::::::.:::::: :: CCDS89 RVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEKMTEE 130 140 150 160 170 180 170 180 190 pF1KB6 EVEALMAGQEDSNGCINYEAFVKHIMSI :::...::.::::::::::::.:::.:. CCDS89 EVETVLAGHEDSNGCINYEAFLKHILSV 190 200 >>CCDS8906.1 MYL6 gene_id:4637|Hs108|chr12 (151 aa) initn: 817 init1: 735 opt: 754 Z-score: 611.4 bits: 119.5 E(32554): 9.8e-28 Smith-Waterman score: 754; 74.3% identity (92.6% similar) in 148 aa overlap (46-193:3-150) 20 30 40 50 60 70 pF1KB6 AAPAPAPAPAPAPAPAKPKEEKIDLSAIKIEFSKEQQDEFKEAFLLFDRTGDSKITLSQV .:...: :::::: :::::::.:: :: CCDS89 MCDFTEDQTAEFKEAFQLFDRTGDGKILYSQC 10 20 30 80 90 100 110 120 130 pF1KB6 GDVLRALGTNPTNAEVRKVLGNPSNEELNAKKIEFEQFLPMMQAISNNKDQATYEDFVEG :::.:::: ::::::: ::::::...:.:.: ..::.::::.:....::::.::::.::: CCDS89 GDVMRALGQNPTNAEVLKVLGNPKSDEMNVKVLDFEHFLPMLQTVAKNKDQGTYEDYVEG 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB6 LRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMAGQEDSNGCINYEAFVKHIMSI ::::::::::::::::.::::.:::::: ::::: :.::.:::::::::::::.::.: CCDS89 LRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVEMLVAGHEDSNGCINYEAFVRHILSG 100 110 120 130 140 150 >>CCDS31834.1 MYL6 gene_id:4637|Hs108|chr12 (151 aa) initn: 788 init1: 706 opt: 725 Z-score: 588.7 bits: 115.4 E(32554): 1.8e-26 Smith-Waterman score: 725; 70.9% identity (91.2% similar) in 148 aa overlap (46-193:3-150) 20 30 40 50 60 70 pF1KB6 AAPAPAPAPAPAPAPAKPKEEKIDLSAIKIEFSKEQQDEFKEAFLLFDRTGDSKITLSQV .:...: :::::: :::::::.:: :: CCDS31 MCDFTEDQTAEFKEAFQLFDRTGDGKILYSQC 10 20 30 80 90 100 110 120 130 pF1KB6 GDVLRALGTNPTNAEVRKVLGNPSNEELNAKKIEFEQFLPMMQAISNNKDQATYEDFVEG :::.:::: ::::::: ::::::...:.:.: ..::.::::.:....::::.::::.::: CCDS31 GDVMRALGQNPTNAEVLKVLGNPKSDEMNVKVLDFEHFLPMLQTVAKNKDQGTYEDYVEG 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB6 LRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMAGQEDSNGCINYEAFVKHIMSI ::::::::::::::::.::::.:::::: ::::: :.::.:::::::::: .:. ... CCDS31 LRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVEMLVAGHEDSNGCINYEELVRMVLNG 100 110 120 130 140 150 >>CCDS7069.1 CALML3 gene_id:810|Hs108|chr10 (149 aa) initn: 462 init1: 174 opt: 404 Z-score: 338.2 bits: 69.0 E(32554): 1.6e-12 Smith-Waterman score: 404; 44.3% identity (75.2% similar) in 149 aa overlap (46-193:4-148) 20 30 40 50 60 70 pF1KB6 AAPAPAPAPAPAPAPAKPKEEKIDLSAIKIEFSKEQQDEFKEAFLLFDRTGDSKITLSQV ....:: :::::: :::. ::. :: .. CCDS70 MADQLTEEQVTEFKEAFSLFDKDGDGCITTREL 10 20 30 80 90 100 110 120 130 pF1KB6 GDVLRALGTNPTNAEVRKVLGNPSNEELNAKKIEFEQFLPMMQAISNNKDQATYEDFVEG : :.:.:: :::.::.: .... . . . ..: .:: :: . :: . :.. :. CCDS70 GTVMRSLGQNPTEAELRDMMSEIDRD--GNGTVDFPEFLGMM--ARKMKDTDNEEEIREA 40 50 60 70 80 140 150 160 170 180 190 pF1KB6 LRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALM-AGQEDSNGCINYEAFVKHIMSI .:::::.::: : .::::::.. ::::...:::. .. :.. :..: .::: ::. ..: CCDS70 FRVFDKDGNGFVSAAELRHVMTRLGEKLSDEEVDEMIRAADTDGDGQVNYEEFVRVLVSK 90 100 110 120 130 140 >>CCDS9892.1 CALM1 gene_id:801|Hs108|chr14 (149 aa) initn: 404 init1: 175 opt: 395 Z-score: 331.2 bits: 67.7 E(32554): 4e-12 Smith-Waterman score: 395; 44.2% identity (74.1% similar) in 147 aa overlap (46-191:4-146) 20 30 40 50 60 70 pF1KB6 AAPAPAPAPAPAPAPAKPKEEKIDLSAIKIEFSKEQQDEFKEAFLLFDRTGDSKITLSQV ....:: :::::: :::. ::. :: ... CCDS98 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKEL 10 20 30 80 90 100 110 120 130 pF1KB6 GDVLRALGTNPTNAEVRKVLGNPSNEELNAKKIEFEQFLPMMQAISNNKDQATYEDFVEG : :.:.:: :::.::.. .. : . . :. :.: .:: :: . :: . :.. :. CCDS98 GTVMRSLGQNPTEAELQDMI-NEVDADGNGT-IDFPEFLTMMA--RKMKDTDSEEEIREA 40 50 60 70 80 140 150 160 170 180 190 pF1KB6 LRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMAGQE-DSNGCINYEAFVKHIMSI .:::::.::: . .::::::...::::. .:::. .. . :..: .::: ::. . CCDS98 FRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 90 100 110 120 130 140 >>CCDS1832.1 CALM2 gene_id:805|Hs108|chr2 (149 aa) initn: 404 init1: 175 opt: 395 Z-score: 331.2 bits: 67.7 E(32554): 4e-12 Smith-Waterman score: 395; 44.2% identity (74.1% similar) in 147 aa overlap (46-191:4-146) 20 30 40 50 60 70 pF1KB6 AAPAPAPAPAPAPAPAKPKEEKIDLSAIKIEFSKEQQDEFKEAFLLFDRTGDSKITLSQV ....:: :::::: :::. ::. :: ... CCDS18 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKEL 10 20 30 80 90 100 110 120 130 pF1KB6 GDVLRALGTNPTNAEVRKVLGNPSNEELNAKKIEFEQFLPMMQAISNNKDQATYEDFVEG : :.:.:: :::.::.. .. : . . :. :.: .:: :: . :: . :.. :. CCDS18 GTVMRSLGQNPTEAELQDMI-NEVDADGNGT-IDFPEFLTMMA--RKMKDTDSEEEIREA 40 50 60 70 80 140 150 160 170 180 190 pF1KB6 LRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMAGQE-DSNGCINYEAFVKHIMSI .:::::.::: . .::::::...::::. .:::. .. . :..: .::: ::. . CCDS18 FRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK 90 100 110 120 130 140 194 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 17:38:41 2016 done: Sat Nov 5 17:38:41 2016 Total Scan time: 2.180 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]