Result of FASTA (omim) for
pF1KB6852
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6852, 194 aa
1>>>pF1KB6852 194 - 194 aa - 194 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.1779+/-0.000342; mu= 7.7106+/- 0.022
mean_var=154.1909+/-31.083, 0's: 0 Z-trim(120.0): 84 B-trim: 1350 in 1/58
Lambda= 0.103287
statistics sampled from 34565 (34650) to 34565 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.731), E-opt: 0.2 (0.406), width: 16
Scan time: 6.290
The best scores are: opt bits E(85289)
NP_524144 (OMIM: 160780) myosin light chain 1/3, s ( 194) 1248 196.5 2.2e-50
NP_524146 (OMIM: 160780) myosin light chain 1/3, s ( 150) 919 147.4 1.1e-35
XP_005257448 (OMIM: 160770) PREDICTED: myosin ligh ( 197) 905 145.4 5.5e-35
NP_002467 (OMIM: 160770) myosin light chain 4 [Hom ( 197) 905 145.4 5.5e-35
NP_001002841 (OMIM: 160770) myosin light chain 4 [ ( 197) 905 145.4 5.5e-35
NP_000249 (OMIM: 160790,608751) myosin light chain ( 195) 890 143.2 2.6e-34
NP_001186558 (OMIM: 609930) myosin light chain 6B ( 208) 838 135.4 5.8e-32
NP_002466 (OMIM: 609930) myosin light chain 6B [Ho ( 208) 838 135.4 5.8e-32
NP_066299 (OMIM: 609931) myosin light polypeptide ( 151) 754 122.8 2.7e-28
NP_524147 (OMIM: 609931) myosin light polypeptide ( 151) 725 118.5 5.4e-27
XP_016880172 (OMIM: 160770) PREDICTED: myosin ligh ( 228) 704 115.5 6.4e-26
XP_011523141 (OMIM: 160770) PREDICTED: myosin ligh ( 228) 704 115.5 6.4e-26
XP_016880173 (OMIM: 160770) PREDICTED: myosin ligh ( 228) 704 115.5 6.4e-26
NP_005176 (OMIM: 114184) calmodulin-like protein 3 ( 149) 404 70.7 1.3e-12
NP_008819 (OMIM: 114180,614916,616247) calmodulin ( 149) 395 69.3 3.4e-12
NP_001734 (OMIM: 114182,616249) calmodulin isoform ( 149) 395 69.3 3.4e-12
NP_005175 (OMIM: 114183) calmodulin isoform 1 [Hom ( 149) 395 69.3 3.4e-12
NP_001316851 (OMIM: 114183) calmodulin isoform 1 [ ( 149) 395 69.3 3.4e-12
XP_006720321 (OMIM: 114180,614916,616247) PREDICTE ( 150) 395 69.3 3.4e-12
NP_001292553 (OMIM: 114182,616249) calmodulin isof ( 197) 395 69.4 4.1e-12
NP_003270 (OMIM: 191039) troponin C, skeletal musc ( 160) 286 53.1 2.8e-07
NP_001316855 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 283 52.5 2.9e-07
NP_001316852 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 283 52.5 2.9e-07
NP_001292554 (OMIM: 114182,616249) calmodulin isof ( 113) 283 52.5 2.9e-07
NP_001316853 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 283 52.5 2.9e-07
NP_001316854 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 283 52.5 2.9e-07
NP_001316850 (OMIM: 114183) calmodulin isoform 2 [ ( 113) 283 52.5 2.9e-07
NP_001292555 (OMIM: 114182,616249) calmodulin isof ( 113) 283 52.5 2.9e-07
XP_011527333 (OMIM: 191039) PREDICTED: troponin C, ( 145) 278 51.9 5.8e-07
NP_003271 (OMIM: 191040,611879,613243) troponin C, ( 161) 266 50.1 2.2e-06
NP_004057 (OMIM: 603187) centrin-1 [Homo sapiens] ( 172) 262 49.5 3.5e-06
NP_059118 (OMIM: 605183) calmodulin-like protein 5 ( 146) 260 49.2 3.8e-06
NP_001305425 (OMIM: 607314,614899) calcium-binding ( 226) 259 49.2 5.8e-06
NP_004335 (OMIM: 300006) centrin-2 [Homo sapiens] ( 172) 253 48.2 8.8e-06
NP_004356 (OMIM: 602907) centrin-3 isoform 2 [Homo ( 167) 249 47.6 1.3e-05
NP_057450 (OMIM: 607314,614899) calcium-binding pr ( 220) 247 47.4 2e-05
NP_619650 (OMIM: 610171) calmodulin-like protein 6 ( 181) 239 46.1 3.9e-05
XP_005244786 (OMIM: 610171) PREDICTED: calmodulin- ( 203) 239 46.2 4.2e-05
NP_001317242 (OMIM: 610171) calmodulin-like protei ( 164) 232 45.1 7.4e-05
NP_001284694 (OMIM: 602907) centrin-3 isoform 1 [H ( 191) 225 44.1 0.00017
NP_062829 (OMIM: 607315) calcium-binding protein 5 ( 173) 221 43.4 0.00024
NP_291024 (OMIM: 609211) myosin regulatory light c ( 172) 218 43.0 0.00033
NP_001138417 (OMIM: 609211) myosin regulatory ligh ( 172) 218 43.0 0.00033
NP_001138416 (OMIM: 609211) myosin regulatory ligh ( 172) 218 43.0 0.00033
XP_016882481 (OMIM: 607315) PREDICTED: calcium-bin ( 284) 221 43.6 0.00035
NP_004267 (OMIM: 605563) calcium-binding protein 1 ( 167) 214 42.4 0.00048
NP_001028849 (OMIM: 605563) calcium-binding protei ( 370) 218 43.3 0.00058
NP_112482 (OMIM: 605563) calcium-binding protein 1 ( 227) 214 42.5 0.00061
NP_000423 (OMIM: 160781,608758) myosin regulatory ( 166) 211 41.9 0.00065
NP_006088 (OMIM: 609905) myosin regulatory light p ( 172) 211 41.9 0.00067
>>NP_524144 (OMIM: 160780) myosin light chain 1/3, skele (194 aa)
initn: 1248 init1: 1248 opt: 1248 Z-score: 1025.4 bits: 196.5 E(85289): 2.2e-50
Smith-Waterman score: 1248; 100.0% identity (100.0% similar) in 194 aa overlap (1-194:1-194)
10 20 30 40 50 60
pF1KB6 MAPKKDVKKPVAAAAAAPAPAPAPAPAPAPAKPKEEKIDLSAIKIEFSKEQQDEFKEAFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_524 MAPKKDVKKPVAAAAAAPAPAPAPAPAPAPAKPKEEKIDLSAIKIEFSKEQQDEFKEAFL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 LFDRTGDSKITLSQVGDVLRALGTNPTNAEVRKVLGNPSNEELNAKKIEFEQFLPMMQAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_524 LFDRTGDSKITLSQVGDVLRALGTNPTNAEVRKVLGNPSNEELNAKKIEFEQFLPMMQAI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 SNNKDQATYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMAGQEDSNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_524 SNNKDQATYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMAGQEDSNG
130 140 150 160 170 180
190
pF1KB6 CINYEAFVKHIMSI
::::::::::::::
NP_524 CINYEAFVKHIMSI
190
>>NP_524146 (OMIM: 160780) myosin light chain 1/3, skele (150 aa)
initn: 919 init1: 919 opt: 919 Z-score: 761.9 bits: 147.4 E(85289): 1.1e-35
Smith-Waterman score: 919; 96.0% identity (97.3% similar) in 150 aa overlap (45-194:1-150)
20 30 40 50 60 70
pF1KB6 AAAPAPAPAPAPAPAPAKPKEEKIDLSAIKIEFSKEQQDEFKEAFLLFDRTGDSKITLSQ
. :: .: :::::::::::::::::::::
NP_524 MSFSADQIAEFKEAFLLFDRTGDSKITLSQ
10 20 30
80 90 100 110 120 130
pF1KB6 VGDVLRALGTNPTNAEVRKVLGNPSNEELNAKKIEFEQFLPMMQAISNNKDQATYEDFVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_524 VGDVLRALGTNPTNAEVRKVLGNPSNEELNAKKIEFEQFLPMMQAISNNKDQATYEDFVE
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB6 GLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMAGQEDSNGCINYEAFVKHIMSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_524 GLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMAGQEDSNGCINYEAFVKHIMSI
100 110 120 130 140 150
>>XP_005257448 (OMIM: 160770) PREDICTED: myosin light ch (197 aa)
initn: 721 init1: 721 opt: 905 Z-score: 749.1 bits: 145.4 E(85289): 5.5e-35
Smith-Waterman score: 905; 71.9% identity (85.2% similar) in 196 aa overlap (1-193:1-196)
10 20 30 40 50
pF1KB6 MAPKK-DVKKPVAAAAAAPAPAPAPAPAPAPAKPKEEKIDLSAIKIEFSKEQQDEFKEAF
::::: . :: .: : :::::::::::::: ::: .: ...::.:. .: .::::::
XP_005 MAPKKPEPKKEAAKPAPAPAPAPAPAPAPAPEAPKEPAFDPKSVKIDFTADQIEEFKEAF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 LLFDRT--GDSKITLSQVGDVLRALGTNPTNAEVRKVLGNPSNEELNAKKIEFEQFLPMM
::::: :. ::: .: :::::::: ::::::: .:::.:. ::.:.: ..:: :::..
XP_005 SLFDRTPTGEMKITYGQCGDVLRALGQNPTNAEVLRVLGKPKPEEMNVKMLDFETFLPIL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 QAISNNKDQATYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMAGQED
: :: ::.:.:::::::::::::::.:::::::::::::::::::: : ::: :.:::::
XP_005 QHISRNKEQGTYEDFVEGLRVFDKESNGTVMGAELRHVLATLGEKMTEAEVEQLLAGQED
130 140 150 160 170 180
180 190
pF1KB6 SNGCINYEAFVKHIMSI
.:::::::::::::::
XP_005 ANGCINYEAFVKHIMSG
190
>>NP_002467 (OMIM: 160770) myosin light chain 4 [Homo sa (197 aa)
initn: 721 init1: 721 opt: 905 Z-score: 749.1 bits: 145.4 E(85289): 5.5e-35
Smith-Waterman score: 905; 71.9% identity (85.2% similar) in 196 aa overlap (1-193:1-196)
10 20 30 40 50
pF1KB6 MAPKK-DVKKPVAAAAAAPAPAPAPAPAPAPAKPKEEKIDLSAIKIEFSKEQQDEFKEAF
::::: . :: .: : :::::::::::::: ::: .: ...::.:. .: .::::::
NP_002 MAPKKPEPKKEAAKPAPAPAPAPAPAPAPAPEAPKEPAFDPKSVKIDFTADQIEEFKEAF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 LLFDRT--GDSKITLSQVGDVLRALGTNPTNAEVRKVLGNPSNEELNAKKIEFEQFLPMM
::::: :. ::: .: :::::::: ::::::: .:::.:. ::.:.: ..:: :::..
NP_002 SLFDRTPTGEMKITYGQCGDVLRALGQNPTNAEVLRVLGKPKPEEMNVKMLDFETFLPIL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 QAISNNKDQATYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMAGQED
: :: ::.:.:::::::::::::::.:::::::::::::::::::: : ::: :.:::::
NP_002 QHISRNKEQGTYEDFVEGLRVFDKESNGTVMGAELRHVLATLGEKMTEAEVEQLLAGQED
130 140 150 160 170 180
180 190
pF1KB6 SNGCINYEAFVKHIMSI
.:::::::::::::::
NP_002 ANGCINYEAFVKHIMSG
190
>>NP_001002841 (OMIM: 160770) myosin light chain 4 [Homo (197 aa)
initn: 721 init1: 721 opt: 905 Z-score: 749.1 bits: 145.4 E(85289): 5.5e-35
Smith-Waterman score: 905; 71.9% identity (85.2% similar) in 196 aa overlap (1-193:1-196)
10 20 30 40 50
pF1KB6 MAPKK-DVKKPVAAAAAAPAPAPAPAPAPAPAKPKEEKIDLSAIKIEFSKEQQDEFKEAF
::::: . :: .: : :::::::::::::: ::: .: ...::.:. .: .::::::
NP_001 MAPKKPEPKKEAAKPAPAPAPAPAPAPAPAPEAPKEPAFDPKSVKIDFTADQIEEFKEAF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 LLFDRT--GDSKITLSQVGDVLRALGTNPTNAEVRKVLGNPSNEELNAKKIEFEQFLPMM
::::: :. ::: .: :::::::: ::::::: .:::.:. ::.:.: ..:: :::..
NP_001 SLFDRTPTGEMKITYGQCGDVLRALGQNPTNAEVLRVLGKPKPEEMNVKMLDFETFLPIL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 QAISNNKDQATYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMAGQED
: :: ::.:.:::::::::::::::.:::::::::::::::::::: : ::: :.:::::
NP_001 QHISRNKEQGTYEDFVEGLRVFDKESNGTVMGAELRHVLATLGEKMTEAEVEQLLAGQED
130 140 150 160 170 180
180 190
pF1KB6 SNGCINYEAFVKHIMSI
.:::::::::::::::
NP_001 ANGCINYEAFVKHIMSG
190
>>NP_000249 (OMIM: 160790,608751) myosin light chain 3 [ (195 aa)
initn: 706 init1: 706 opt: 890 Z-score: 737.1 bits: 143.2 E(85289): 2.6e-34
Smith-Waterman score: 890; 72.3% identity (83.1% similar) in 195 aa overlap (1-193:1-194)
10 20 30 40 50 60
pF1KB6 MAPKKDVKKPVAAAAAAPAPAPAPAPAPAPAKPKEEKIDLSAIKIEFSKEQQDEFKEAFL
::::: : : ::: :::::: : : .::: ..: : :::::. :: .::::::.
NP_000 MAPKKPEPKK-DDAKAAPKAAPAPAPPPEPERPKEVEFDASKIKIEFTPEQIEEFKEAFM
10 20 30 40 50
70 80 90 100 110
pF1KB6 LFDRTG--DSKITLSQVGDVLRALGTNPTNAEVRKVLGNPSNEELNAKKIEFEQFLPMMQ
::::: . ::: .: :::::::: :::.::: .:::.: .::::.: ..:: ::::.:
NP_000 LFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 AISNNKDQATYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMAGQEDS
::.::: .::::::::::::::::::::::::::::::::::.. :.::: ::::::::
NP_000 HISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDS
120 130 140 150 160 170
180 190
pF1KB6 NGCINYEAFVKHIMSI
:::::::::::::::
NP_000 NGCINYEAFVKHIMSS
180 190
>>NP_001186558 (OMIM: 609930) myosin light chain 6B [Hom (208 aa)
initn: 1018 init1: 827 opt: 838 Z-score: 694.8 bits: 135.4 E(85289): 5.8e-32
Smith-Waterman score: 853; 62.5% identity (81.2% similar) in 208 aa overlap (1-194:1-208)
10 20 30 40
pF1KB6 MAPKKDV--KKPVAAAAAAPAPAPAPAPAP------------APAKPKEEKIDLSAIKIE
: ::::: :::.. . . :: :: : :: :: : .: .::: . ::
NP_001 MPPKKDVPVKKPAGPSISKPAAKPAAAGAPPAKTKAEPAVPQAPQKTQEPPVDLSKVVIE
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB6 FSKEQQDEFKEAFLLFDRTGDSKITLSQVGDVLRALGTNPTNAEVRKVLGNPSNEELNAK
:.:.: .:::::: ::::.::.:: :: :::.:::: ::::::: ::::::...::...
NP_001 FNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKSR
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB6 KIEFEQFLPMMQAISNNKDQATYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEE
...:: ::::.::...:. :.::::..::.::::::::: ::::::::::.:::::: ::
NP_001 RVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEKMTEE
130 140 150 160 170 180
170 180 190
pF1KB6 EVEALMAGQEDSNGCINYEAFVKHIMSI
:::...::.::::::::::::.:::.:.
NP_001 EVETVLAGHEDSNGCINYEAFLKHILSV
190 200
>>NP_002466 (OMIM: 609930) myosin light chain 6B [Homo s (208 aa)
initn: 1018 init1: 827 opt: 838 Z-score: 694.8 bits: 135.4 E(85289): 5.8e-32
Smith-Waterman score: 853; 62.5% identity (81.2% similar) in 208 aa overlap (1-194:1-208)
10 20 30 40
pF1KB6 MAPKKDV--KKPVAAAAAAPAPAPAPAPAP------------APAKPKEEKIDLSAIKIE
: ::::: :::.. . . :: :: : :: :: : .: .::: . ::
NP_002 MPPKKDVPVKKPAGPSISKPAAKPAAAGAPPAKTKAEPAVPQAPQKTQEPPVDLSKVVIE
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB6 FSKEQQDEFKEAFLLFDRTGDSKITLSQVGDVLRALGTNPTNAEVRKVLGNPSNEELNAK
:.:.: .:::::: ::::.::.:: :: :::.:::: ::::::: ::::::...::...
NP_002 FNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKSR
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB6 KIEFEQFLPMMQAISNNKDQATYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMKEE
...:: ::::.::...:. :.::::..::.::::::::: ::::::::::.:::::: ::
NP_002 RVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEKMTEE
130 140 150 160 170 180
170 180 190
pF1KB6 EVEALMAGQEDSNGCINYEAFVKHIMSI
:::...::.::::::::::::.:::.:.
NP_002 EVETVLAGHEDSNGCINYEAFLKHILSV
190 200
>>NP_066299 (OMIM: 609931) myosin light polypeptide 6 is (151 aa)
initn: 817 init1: 735 opt: 754 Z-score: 629.0 bits: 122.8 E(85289): 2.7e-28
Smith-Waterman score: 754; 74.3% identity (92.6% similar) in 148 aa overlap (46-193:3-150)
20 30 40 50 60 70
pF1KB6 AAPAPAPAPAPAPAPAKPKEEKIDLSAIKIEFSKEQQDEFKEAFLLFDRTGDSKITLSQV
.:...: :::::: :::::::.:: ::
NP_066 MCDFTEDQTAEFKEAFQLFDRTGDGKILYSQC
10 20 30
80 90 100 110 120 130
pF1KB6 GDVLRALGTNPTNAEVRKVLGNPSNEELNAKKIEFEQFLPMMQAISNNKDQATYEDFVEG
:::.:::: ::::::: ::::::...:.:.: ..::.::::.:....::::.::::.:::
NP_066 GDVMRALGQNPTNAEVLKVLGNPKSDEMNVKVLDFEHFLPMLQTVAKNKDQGTYEDYVEG
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB6 LRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMAGQEDSNGCINYEAFVKHIMSI
::::::::::::::::.::::.:::::: ::::: :.::.:::::::::::::.::.:
NP_066 LRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVEMLVAGHEDSNGCINYEAFVRHILSG
100 110 120 130 140 150
>>NP_524147 (OMIM: 609931) myosin light polypeptide 6 is (151 aa)
initn: 788 init1: 706 opt: 725 Z-score: 605.7 bits: 118.5 E(85289): 5.4e-27
Smith-Waterman score: 725; 70.9% identity (91.2% similar) in 148 aa overlap (46-193:3-150)
20 30 40 50 60 70
pF1KB6 AAPAPAPAPAPAPAPAKPKEEKIDLSAIKIEFSKEQQDEFKEAFLLFDRTGDSKITLSQV
.:...: :::::: :::::::.:: ::
NP_524 MCDFTEDQTAEFKEAFQLFDRTGDGKILYSQC
10 20 30
80 90 100 110 120 130
pF1KB6 GDVLRALGTNPTNAEVRKVLGNPSNEELNAKKIEFEQFLPMMQAISNNKDQATYEDFVEG
:::.:::: ::::::: ::::::...:.:.: ..::.::::.:....::::.::::.:::
NP_524 GDVMRALGQNPTNAEVLKVLGNPKSDEMNVKVLDFEHFLPMLQTVAKNKDQGTYEDYVEG
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB6 LRVFDKEGNGTVMGAELRHVLATLGEKMKEEEVEALMAGQEDSNGCINYEAFVKHIMSI
::::::::::::::::.::::.:::::: ::::: :.::.:::::::::: .:. ...
NP_524 LRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVEMLVAGHEDSNGCINYEELVRMVLNG
100 110 120 130 140 150
194 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 17:38:42 2016 done: Sat Nov 5 17:38:43 2016
Total Scan time: 6.290 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]