FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6853, 177 aa 1>>>pF1KB6853 177 - 177 aa - 177 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.6681+/-0.00046; mu= -11.8313+/- 0.029 mean_var=270.3858+/-56.383, 0's: 0 Z-trim(118.0): 7 B-trim: 39 in 1/54 Lambda= 0.077998 statistics sampled from 30576 (30583) to 30576 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.695), E-opt: 0.2 (0.359), width: 16 Scan time: 6.080 The best scores are: opt bits E(85289) NP_620167 (OMIM: 615154) DPY30 domain-containing p ( 177) 1122 138.6 5e-33 NP_001255982 (OMIM: 615154) DPY30 domain-containin ( 177) 1122 138.6 5e-33 XP_011537637 (OMIM: 615154) PREDICTED: DPY30 domai ( 177) 1122 138.6 5e-33 XP_005269606 (OMIM: 615154) PREDICTED: DPY30 domai ( 184) 1079 133.8 1.5e-31 XP_005269607 (OMIM: 615154) PREDICTED: DPY30 domai ( 184) 1079 133.8 1.5e-31 XP_011537636 (OMIM: 615154) PREDICTED: DPY30 domai ( 184) 1079 133.8 1.5e-31 XP_016871238 (OMIM: 615154) PREDICTED: DPY30 domai ( 171) 1067 132.4 3.5e-31 >>NP_620167 (OMIM: 615154) DPY30 domain-containing prote (177 aa) initn: 1122 init1: 1122 opt: 1122 Z-score: 714.0 bits: 138.6 E(85289): 5e-33 Smith-Waterman score: 1122; 100.0% identity (100.0% similar) in 177 aa overlap (1-177:1-177) 10 20 30 40 50 60 pF1KB6 MESIYLQKHLGACLTQGLAEVARVRPVDPIEYLALWIYKYKENVTMEQLRQKEMAKLERE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 MESIYLQKHLGACLTQGLAEVARVRPVDPIEYLALWIYKYKENVTMEQLRQKEMAKLERE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 RELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQLGKEMRMNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 RELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQLGKEMRMNM 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 ENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEELDEPMFSDIALNIDQDL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_620 ENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEELDEPMFSDIALNIDQDL 130 140 150 160 170 >>NP_001255982 (OMIM: 615154) DPY30 domain-containing pr (177 aa) initn: 1122 init1: 1122 opt: 1122 Z-score: 714.0 bits: 138.6 E(85289): 5e-33 Smith-Waterman score: 1122; 100.0% identity (100.0% similar) in 177 aa overlap (1-177:1-177) 10 20 30 40 50 60 pF1KB6 MESIYLQKHLGACLTQGLAEVARVRPVDPIEYLALWIYKYKENVTMEQLRQKEMAKLERE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MESIYLQKHLGACLTQGLAEVARVRPVDPIEYLALWIYKYKENVTMEQLRQKEMAKLERE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 RELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQLGKEMRMNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQLGKEMRMNM 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 ENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEELDEPMFSDIALNIDQDL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEELDEPMFSDIALNIDQDL 130 140 150 160 170 >>XP_011537637 (OMIM: 615154) PREDICTED: DPY30 domain-co (177 aa) initn: 1122 init1: 1122 opt: 1122 Z-score: 714.0 bits: 138.6 E(85289): 5e-33 Smith-Waterman score: 1122; 100.0% identity (100.0% similar) in 177 aa overlap (1-177:1-177) 10 20 30 40 50 60 pF1KB6 MESIYLQKHLGACLTQGLAEVARVRPVDPIEYLALWIYKYKENVTMEQLRQKEMAKLERE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MESIYLQKHLGACLTQGLAEVARVRPVDPIEYLALWIYKYKENVTMEQLRQKEMAKLERE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 RELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQLGKEMRMNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQLGKEMRMNM 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 ENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEELDEPMFSDIALNIDQDL ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEELDEPMFSDIALNIDQDL 130 140 150 160 170 >>XP_005269606 (OMIM: 615154) PREDICTED: DPY30 domain-co (184 aa) initn: 1242 init1: 1079 opt: 1079 Z-score: 687.5 bits: 133.8 E(85289): 1.5e-31 Smith-Waterman score: 1079; 97.1% identity (100.0% similar) in 173 aa overlap (1-173:1-173) 10 20 30 40 50 60 pF1KB6 MESIYLQKHLGACLTQGLAEVARVRPVDPIEYLALWIYKYKENVTMEQLRQKEMAKLERE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MESIYLQKHLGACLTQGLAEVARVRPVDPIEYLALWIYKYKENVTMEQLRQKEMAKLERE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 RELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQLGKEMRMNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQLGKEMRMNM 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 ENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEELDEPMFSDIALNIDQDL ::::::::::::::::::::::::::::::::::::::::::::::::..... XP_005 ENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEELDEPMFSDVSISVFCEKTRF 130 140 150 160 170 180 XP_005 CFCF >>XP_005269607 (OMIM: 615154) PREDICTED: DPY30 domain-co (184 aa) initn: 1242 init1: 1079 opt: 1079 Z-score: 687.5 bits: 133.8 E(85289): 1.5e-31 Smith-Waterman score: 1079; 97.1% identity (100.0% similar) in 173 aa overlap (1-173:1-173) 10 20 30 40 50 60 pF1KB6 MESIYLQKHLGACLTQGLAEVARVRPVDPIEYLALWIYKYKENVTMEQLRQKEMAKLERE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MESIYLQKHLGACLTQGLAEVARVRPVDPIEYLALWIYKYKENVTMEQLRQKEMAKLERE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 RELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQLGKEMRMNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 RELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQLGKEMRMNM 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 ENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEELDEPMFSDIALNIDQDL ::::::::::::::::::::::::::::::::::::::::::::::::..... XP_005 ENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEELDEPMFSDVSISVFCEKTRF 130 140 150 160 170 180 XP_005 CFCF >>XP_011537636 (OMIM: 615154) PREDICTED: DPY30 domain-co (184 aa) initn: 1242 init1: 1079 opt: 1079 Z-score: 687.5 bits: 133.8 E(85289): 1.5e-31 Smith-Waterman score: 1079; 97.1% identity (100.0% similar) in 173 aa overlap (1-173:1-173) 10 20 30 40 50 60 pF1KB6 MESIYLQKHLGACLTQGLAEVARVRPVDPIEYLALWIYKYKENVTMEQLRQKEMAKLERE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MESIYLQKHLGACLTQGLAEVARVRPVDPIEYLALWIYKYKENVTMEQLRQKEMAKLERE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 RELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQLGKEMRMNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 RELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQLGKEMRMNM 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 ENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEELDEPMFSDIALNIDQDL ::::::::::::::::::::::::::::::::::::::::::::::::..... XP_011 ENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEELDEPMFSDVSISVFCEKTRF 130 140 150 160 170 180 XP_011 CFCF >>XP_016871238 (OMIM: 615154) PREDICTED: DPY30 domain-co (171 aa) initn: 1067 init1: 1067 opt: 1067 Z-score: 680.7 bits: 132.4 E(85289): 3.5e-31 Smith-Waterman score: 1067; 100.0% identity (100.0% similar) in 168 aa overlap (1-168:1-168) 10 20 30 40 50 60 pF1KB6 MESIYLQKHLGACLTQGLAEVARVRPVDPIEYLALWIYKYKENVTMEQLRQKEMAKLERE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MESIYLQKHLGACLTQGLAEVARVRPVDPIEYLALWIYKYKENVTMEQLRQKEMAKLERE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 RELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQLGKEMRMNM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQLGKEMRMNM 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 ENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEELDEPMFSDIALNIDQDL :::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEELDEPMFSDDCL 130 140 150 160 170 177 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Mon Nov 7 20:17:04 2016 done: Mon Nov 7 20:17:05 2016 Total Scan time: 6.080 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]