FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6857, 179 aa 1>>>pF1KB6857 179 - 179 aa - 179 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.6073+/-0.000881; mu= -0.9879+/- 0.053 mean_var=192.5917+/-37.971, 0's: 0 Z-trim(113.3): 13 B-trim: 0 in 0/53 Lambda= 0.092418 statistics sampled from 13954 (13965) to 13954 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.763), E-opt: 0.2 (0.429), width: 16 Scan time: 2.220 The best scores are: opt bits E(32554) CCDS43748.1 STMN2 gene_id:11075|Hs108|chr8 ( 179) 1119 160.4 5.4e-40 CCDS56542.1 STMN2 gene_id:11075|Hs108|chr8 ( 187) 1001 144.7 3.1e-35 CCDS13529.1 STMN3 gene_id:50861|Hs108|chr20 ( 180) 808 118.9 1.7e-27 CCDS63330.1 STMN3 gene_id:50861|Hs108|chr20 ( 169) 763 112.9 1e-25 CCDS269.1 STMN1 gene_id:3925|Hs108|chr1 ( 149) 610 92.5 1.3e-19 CCDS64852.1 STMN4 gene_id:81551|Hs108|chr8 ( 189) 601 91.3 3.5e-19 CCDS6055.1 STMN4 gene_id:81551|Hs108|chr8 ( 216) 601 91.4 3.9e-19 CCDS44090.1 STMN1 gene_id:3925|Hs108|chr1 ( 174) 557 85.5 1.9e-17 CCDS64851.1 STMN4 gene_id:81551|Hs108|chr8 ( 167) 540 83.2 8.9e-17 CCDS64854.1 STMN4 gene_id:81551|Hs108|chr8 ( 203) 540 83.2 1e-16 >>CCDS43748.1 STMN2 gene_id:11075|Hs108|chr8 (179 aa) initn: 1119 init1: 1119 opt: 1119 Z-score: 831.5 bits: 160.4 E(32554): 5.4e-40 Smith-Waterman score: 1119; 100.0% identity (100.0% similar) in 179 aa overlap (1-179:1-179) 10 20 30 40 50 60 pF1KB6 MAKTAMAYKEKMKELSMLSLICSCFYPEPRNINIYTYDDMEVKQINKRASGQAFELILKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 MAKTAMAYKEKMKELSMLSLICSCFYPEPRNINIYTYDDMEVKQINKRASGQAFELILKP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 PSPISEAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 PSPISEAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKA 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 LEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKELQVELSG ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS43 LEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKELQVELSG 130 140 150 160 170 >>CCDS56542.1 STMN2 gene_id:11075|Hs108|chr8 (187 aa) initn: 1001 init1: 1001 opt: 1001 Z-score: 746.2 bits: 144.7 E(32554): 3.1e-35 Smith-Waterman score: 1001; 100.0% identity (100.0% similar) in 160 aa overlap (1-160:1-160) 10 20 30 40 50 60 pF1KB6 MAKTAMAYKEKMKELSMLSLICSCFYPEPRNINIYTYDDMEVKQINKRASGQAFELILKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 MAKTAMAYKEKMKELSMLSLICSCFYPEPRNINIYTYDDMEVKQINKRASGQAFELILKP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 PSPISEAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 PSPISEAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKA 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 LEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKELQVELSG :::::::::::::::::::::::::::::::::::::::: CCDS56 LEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQEKLVKFISSELKESIESQFLEL 130 140 150 160 170 180 CCDS56 QREGEKQ >>CCDS13529.1 STMN3 gene_id:50861|Hs108|chr20 (180 aa) initn: 510 init1: 510 opt: 808 Z-score: 607.3 bits: 118.9 E(32554): 1.7e-27 Smith-Waterman score: 808; 72.8% identity (86.7% similar) in 180 aa overlap (1-179:1-180) 10 20 30 40 50 60 pF1KB6 MAKTAMAYKEKMKELSMLSLICSCFYPEPRNINIYTYDDMEVKQINKRASGQAFELILKP ::.: ::::::::::.::::::::: .:. ..: : ::::::..::::::.::.::: CCDS13 MASTISAYKEKMKELSVLSLICSCFYTQPHPNTVYQYGDMEVKQLDKRASGQSFEVILKS 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 PSPIS-EAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQK :: .: :.: . ::::: ::::.::.:::::::::.:::::::::::.::::::::.: CCDS13 PSDLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHK 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 ALEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKELQVELSG :::::::::..::::: ::: :: :::.:::. :::.::: :::::::::: . :.:: CCDS13 ALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREEMSG 130 140 150 160 170 180 >>CCDS63330.1 STMN3 gene_id:50861|Hs108|chr20 (169 aa) initn: 510 init1: 510 opt: 763 Z-score: 575.3 bits: 112.9 E(32554): 1e-25 Smith-Waterman score: 763; 72.8% identity (87.0% similar) in 169 aa overlap (12-179:1-169) 10 20 30 40 50 60 pF1KB6 MAKTAMAYKEKMKELSMLSLICSCFYPEPRNINIYTYDDMEVKQINKRASGQAFELILKP :::::.::::::::: .:. ..: : ::::::..::::::.::.::: CCDS63 MKELSVLSLICSCFYTQPHPNTVYQYGDMEVKQLDKRASGQSFEVILKS 10 20 30 40 70 80 90 100 110 pF1KB6 PSPIS-EAPRTLASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQK :: .: :.: . ::::: ::::.::.:::::::::.:::::::::::.::::::::.: CCDS63 PSDLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHK 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB6 ALEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKELQVELSG :::::::::..::::: ::: :: :::.:::. :::.::: :::::::::: . :.:: CCDS63 ALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREEMSG 110 120 130 140 150 160 >>CCDS269.1 STMN1 gene_id:3925|Hs108|chr1 (149 aa) initn: 610 init1: 610 opt: 610 Z-score: 465.8 bits: 92.5 E(32554): 1.3e-19 Smith-Waterman score: 610; 74.6% identity (88.1% similar) in 134 aa overlap (39-172:5-138) 10 20 30 40 50 60 pF1KB6 KEKMKELSMLSLICSCFYPEPRNINIYTYDDMEVKQINKRASGQAFELILKPPSPISEAP :..::...::::::::::::.: : : CCDS26 MASSDIQVKELEKRASGQAFELILSPRSKESVPE 10 20 30 70 80 90 100 110 120 pF1KB6 RTLASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFS :. ::::::::::::::::::::::::.::.::::::::::::.::::::.::::::: CCDS26 FPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFS 40 50 60 70 80 90 130 140 150 160 170 pF1KB6 KMAEEKLILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKELQVELSG ::::::: ::: ::::::..:: .:::.::..: :::.::: CCDS26 KMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKDPADETEAD 100 110 120 130 140 >>CCDS64852.1 STMN4 gene_id:81551|Hs108|chr8 (189 aa) initn: 755 init1: 590 opt: 601 Z-score: 457.9 bits: 91.3 E(32554): 3.5e-19 Smith-Waterman score: 698; 63.3% identity (80.3% similar) in 188 aa overlap (4-178:2-188) 10 20 30 40 pF1KB6 MAKTAMAYKEKMKELSMLSLICSCFYPEPRNINIYTYD------------DMEVKQINKR : ::::::::: ..::.:::: .: : . : :. :::: ..:: CCDS64 MTLAAYKEKMKELPLVSLFCSCFLADPLNKSSYKYEADTVDLNWCVISDMEVIELNKC 10 20 30 40 50 50 60 70 80 90 100 pF1KB6 ASGQAFELILKPPSPISEAPRTLAS-PKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLA .:::.::.:::::: .. .:. :: :...: ::::::::::::::::: :::..::.:: CCDS64 TSGQSFEVILKPPS-FDGVPEFNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLA 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB6 EKREHEREVLQKALEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQEKERHAAEV :::::::::.:::.:::::: :::.::: :::. ::::::.:::..::::::..:: :: CCDS64 EKREHEREVIQKAIEENNNFIKMAKEKLAQKMESNKENREAHLAAMLERLQEKDKHAEEV 120 130 140 150 160 170 170 pF1KB6 RRNKELQVELSG :.::::. : : CCDS64 RKNKELKEEASR 180 >>CCDS6055.1 STMN4 gene_id:81551|Hs108|chr8 (216 aa) initn: 770 init1: 590 opt: 601 Z-score: 457.0 bits: 91.4 E(32554): 3.9e-19 Smith-Waterman score: 637; 55.5% identity (70.6% similar) in 211 aa overlap (8-178:6-215) 10 20 30 pF1KB6 MAKTAMAYKEKMKELSMLSLICSCFYPEPRNINIYTYD---------------------- :::::::: ..::.:::: .: : . : :. CCDS60 MTLAAYKEKMKELPLVSLFCSCFLADPLNKSSYKYEGWCGRQCRRKDESQRKDSADWR 10 20 30 40 50 40 50 60 70 80 pF1KB6 -----------------DMEVKQINKRASGQAFELILKPPSPISEAPRTLAS-PKKKDLS :::: ..:: .:::.::.:::::: .. .:. :: :...: : CCDS60 ERRAQADTVDLNWCVISDMEVIELNKCTSGQSFEVILKPPS-FDGVPEFNASLPRRRDPS 60 70 80 90 100 110 90 100 110 120 130 140 pF1KB6 LEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKME :::::::::::::::: :::..::.:::::::::::.:::.:::::: :::.::: ::: CCDS60 LEEIQKKLEAAEERRKYQEAELLKHLAEKREHEREVIQKAIEENNNFIKMAKEKLAQKME 120 130 140 150 160 170 150 160 170 pF1KB6 QIKENREANLAAIIERLQEKERHAAEVRRNKELQVELSG . ::::::.:::..::::::..:: :::.::::. : : CCDS60 SNKENREAHLAAMLERLQEKDKHAEEVRKNKELKEEASR 180 190 200 210 >>CCDS44090.1 STMN1 gene_id:3925|Hs108|chr1 (174 aa) initn: 557 init1: 557 opt: 557 Z-score: 426.7 bits: 85.5 E(32554): 1.9e-17 Smith-Waterman score: 557; 76.2% identity (88.5% similar) in 122 aa overlap (39-160:5-126) 10 20 30 40 50 60 pF1KB6 KEKMKELSMLSLICSCFYPEPRNINIYTYDDMEVKQINKRASGQAFELILKPPSPISEAP :..::...::::::::::::.: : : CCDS44 MASSDIQVKELEKRASGQAFELILSPRSKESVPE 10 20 30 70 80 90 100 110 120 pF1KB6 RTLASPKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFS :. ::::::::::::::::::::::::.::.::::::::::::.::::::.::::::: CCDS44 FPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFS 40 50 60 70 80 90 130 140 150 160 170 pF1KB6 KMAEEKLILKMEQIKENREANLAAIIERLQEKERHAAEVRRNKELQVELSG ::::::: ::: ::::::..:: .:::.:: CCDS44 KMAEEKLTHKMEANKENREAQMAAKLERLREKMYFWTHGPGAHPAQISAEQSCLHSVPAL 100 110 120 130 140 150 CCDS44 CPALGLQSALITWSDLSHHH 160 170 >>CCDS64851.1 STMN4 gene_id:81551|Hs108|chr8 (167 aa) initn: 605 init1: 529 opt: 540 Z-score: 414.7 bits: 83.2 E(32554): 8.9e-17 Smith-Waterman score: 604; 62.9% identity (79.6% similar) in 167 aa overlap (12-165:1-166) 10 20 30 40 pF1KB6 MAKTAMAYKEKMKELSMLSLICSCFYPEPRNINIYTYD------------DMEVKQINKR :::: ..::.:::: .: : . : :. :::: ..:: CCDS64 MKELPLVSLFCSCFLADPLNKSSYKYEADTVDLNWCVISDMEVIELNKC 10 20 30 40 50 60 70 80 90 100 pF1KB6 ASGQAFELILKPPSPISEAPRTLAS-PKKKDLSLEEIQKKLEAAEERRKSQEAQVLKQLA .:::.::.:::::: .. .:. :: :...: ::::::::::::::::: :::..::.:: CCDS64 TSGQSFEVILKPPS-FDGVPEFNASLPRRRDPSLEEIQKKLEAAEERRKYQEAELLKHLA 50 60 70 80 90 100 110 120 130 140 150 160 pF1KB6 EKREHEREVLQKALEENNNFSKMAEEKLILKMEQIKENREANLAAIIERLQEKERHAAEV :::::::::.:::.:::::: :::.::: :::. ::::::.:::..::::::: :: CCDS64 EKREHEREVIQKAIEENNNFIKMAKEKLAQKMESNKENREAHLAAMLERLQEKEPPAAR 110 120 130 140 150 160 170 pF1KB6 RRNKELQVELSG >>CCDS64854.1 STMN4 gene_id:81551|Hs108|chr8 (203 aa) initn: 529 init1: 529 opt: 540 Z-score: 413.5 bits: 83.2 E(32554): 1e-16 Smith-Waterman score: 576; 55.1% identity (69.2% similar) in 198 aa overlap (8-165:6-202) 10 20 30 pF1KB6 MAKTAMAYKEKMKELSMLSLICSCFYPEPRNINIYTYD---------------------- :::::::: ..::.:::: .: : . : :. CCDS64 MTLAAYKEKMKELPLVSLFCSCFLADPLNKSSYKYEGWCGRQCRRKDESQRKDSADWR 10 20 30 40 50 40 50 60 70 80 pF1KB6 -----------------DMEVKQINKRASGQAFELILKPPSPISEAPRTLAS-PKKKDLS :::: ..:: .:::.::.:::::: .. .:. :: :...: : CCDS64 ERRAQADTVDLNWCVISDMEVIELNKCTSGQSFEVILKPPS-FDGVPEFNASLPRRRDPS 60 70 80 90 100 110 90 100 110 120 130 140 pF1KB6 LEEIQKKLEAAEERRKSQEAQVLKQLAEKREHEREVLQKALEENNNFSKMAEEKLILKME :::::::::::::::: :::..::.:::::::::::.:::.:::::: :::.::: ::: CCDS64 LEEIQKKLEAAEERRKYQEAELLKHLAEKREHEREVIQKAIEENNNFIKMAKEKLAQKME 120 130 140 150 160 170 150 160 170 pF1KB6 QIKENREANLAAIIERLQEKERHAAEVRRNKELQVELSG . ::::::.:::..::::::: :: CCDS64 SNKENREAHLAAMLERLQEKEPPAAR 180 190 200 179 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 18:19:15 2016 done: Sat Nov 5 18:19:15 2016 Total Scan time: 2.220 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]