FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6858, 194 aa 1>>>pF1KB6858 194 - 194 aa - 194 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.9260+/-0.000286; mu= 5.8558+/- 0.018 mean_var=101.3296+/-20.076, 0's: 0 Z-trim(120.2): 5 B-trim: 0 in 0/59 Lambda= 0.127411 statistics sampled from 35115 (35120) to 35115 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.781), E-opt: 0.2 (0.412), width: 16 Scan time: 6.610 The best scores are: opt bits E(85289) NP_004043 (OMIM: 603293) BCL2/adenovirus E1B 19 kD ( 259) 1285 245.8 4.4e-65 NP_004322 (OMIM: 605368) BCL2/adenovirus E1B 19 kD ( 219) 723 142.4 4.8e-34 NP_001317420 (OMIM: 605368) BCL2/adenovirus E1B 19 ( 179) 704 138.9 4.5e-33 >>NP_004043 (OMIM: 603293) BCL2/adenovirus E1B 19 kDa pr (259 aa) initn: 1285 init1: 1285 opt: 1285 Z-score: 1289.4 bits: 245.8 E(85289): 4.4e-65 Smith-Waterman score: 1285; 100.0% identity (100.0% similar) in 194 aa overlap (1-194:66-259) 10 20 30 pF1KB6 MSQNGAPGMQEESLQGSWVELHFSNNGNGG :::::::::::::::::::::::::::::: NP_004 APTSAFPPPAAEAHPAARRGLRSPQLPSGAMSQNGAPGMQEESLQGSWVELHFSNNGNGG 40 50 60 70 80 90 40 50 60 70 80 90 pF1KB6 SVPASVSIYNGDMEKILLDAQHESGRSSSKSSHCDSPPRSQTPQDTNRASETDTHSIGEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 SVPASVSIYNGDMEKILLDAQHESGRSSSKSSHCDSPPRSQTPQDTNRASETDTHSIGEK 100 110 120 130 140 150 100 110 120 130 140 150 pF1KB6 NSSQSEEDDIERRKEVESILKKNSDWIWDWSSRPENIPPKEFLFKHPKRTATLSMRNTSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 NSSQSEEDDIERRKEVESILKKNSDWIWDWSSRPENIPPKEFLFKHPKRTATLSMRNTSV 160 170 180 190 200 210 160 170 180 190 pF1KB6 MKKGGIFSAEFLKVFLPSLLLSHLLAIGLGIYIGRRLTTSTSTF :::::::::::::::::::::::::::::::::::::::::::: NP_004 MKKGGIFSAEFLKVFLPSLLLSHLLAIGLGIYIGRRLTTSTSTF 220 230 240 250 >>NP_004322 (OMIM: 605368) BCL2/adenovirus E1B 19 kDa pr (219 aa) initn: 629 init1: 446 opt: 723 Z-score: 732.3 bits: 142.4 E(85289): 4.8e-34 Smith-Waterman score: 723; 62.4% identity (84.0% similar) in 194 aa overlap (14-194:32-219) 10 20 30 pF1KB6 MSQNGAPGMQEESLQGSWVELHF-SNNGN-------GG--SVP :..::::: . :.::: :: :: NP_004 SSHLVEPPPPLHNNNNNCEENEQSLPPPAGLNSSWVELPMNSSNGNDNGNGKNGGLEHVP 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB6 ASVSIYNGDMEKILLDAQHESGRSSSK-SSHCDSPPRSQTPQDTNRAS-ETDTHSIGEKN .: ::.::::::::::::::::.:::. ::::::: .::. .. ... :. .. . NP_004 SSSSIHNGDMEKILLDAQHESGQSSSRGSSHCDSP----SPQEDGQIMFDVEMHT-SRDH 70 80 90 100 110 100 110 120 130 140 150 pF1KB6 SSQSEEDDIERRKEVESILKKNSDWIWDWSSRPENIPPKEFLFKHPKRTATLSMRNTSVM ::::::. .: .::::. :::..::. :::::::::::::: :.::::...::::....: NP_004 SSQSEEEVVEGEKEVEA-LKKSADWVSDWSSRPENIPPKEFHFRHPKRSVSLSMRKSGAM 120 130 140 150 160 170 160 170 180 190 pF1KB6 KKGGIFSAEFLKVFLPSLLLSHLLAIGLGIYIGRRLTT-STSTF ::::::::::::::.:::.:::.::.:::::::.::.: :.::. NP_004 KKGGIFSAEFLKVFIPSLFLSHVLALGLGIYIGKRLSTPSASTY 180 190 200 210 >>NP_001317420 (OMIM: 605368) BCL2/adenovirus E1B 19 kDa (179 aa) initn: 606 init1: 446 opt: 704 Z-score: 714.8 bits: 138.9 E(85289): 4.5e-33 Smith-Waterman score: 704; 64.6% identity (86.9% similar) in 175 aa overlap (25-194:11-179) 10 20 30 40 50 pF1KB6 MSQNGAPGMQEESLQGSWVELHFSNNGNGG--SVPASVSIYNGDMEKILLDAQHESGRSS :. ::: ::.: ::.::::::::::::::::.:: NP_001 MNSSNGNDNGNGKNGGLEHVPSSSSIHNGDMEKILLDAQHESGQSS 10 20 30 40 60 70 80 90 100 110 pF1KB6 SK-SSHCDSPPRSQTPQDTNRAS-ETDTHSIGEKNSSQSEEDDIERRKEVESILKKNSDW :. ::::::: .::. .. ... :. .. .::::::. .: .::::. :::..:: NP_001 SRGSSHCDSP----SPQEDGQIMFDVEMHT-SRDHSSQSEEEVVEGEKEVEA-LKKSADW 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB6 IWDWSSRPENIPPKEFLFKHPKRTATLSMRNTSVMKKGGIFSAEFLKVFLPSLLLSHLLA . :::::::::::::: :.::::...::::....:::::::::::::::.:::.:::.:: NP_001 VSDWSSRPENIPPKEFHFRHPKRSVSLSMRKSGAMKKGGIFSAEFLKVFIPSLFLSHVLA 110 120 130 140 150 160 180 190 pF1KB6 IGLGIYIGRRLTT-STSTF .:::::::.::.: :.::. NP_001 LGLGIYIGKRLSTPSASTY 170 194 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 14:39:17 2016 done: Fri Nov 4 14:39:18 2016 Total Scan time: 6.610 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]