FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6860, 187 aa 1>>>pF1KB6860 187 - 187 aa - 187 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.6466+/-0.000658; mu= 17.1868+/- 0.040 mean_var=66.5215+/-13.543, 0's: 0 Z-trim(111.1): 18 B-trim: 0 in 0/49 Lambda= 0.157251 statistics sampled from 12105 (12123) to 12105 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.749), E-opt: 0.2 (0.372), width: 16 Scan time: 1.650 The best scores are: opt bits E(32554) CCDS10408.1 NME4 gene_id:4833|Hs108|chr16 ( 187) 1278 297.9 2.4e-81 CCDS66886.1 NME4 gene_id:4833|Hs108|chr16 ( 117) 786 186.1 6.9e-48 CCDS10443.1 NME3 gene_id:4832|Hs108|chr16 ( 169) 652 155.8 1.3e-38 CCDS11579.1 NME1 gene_id:4830|Hs108|chr17 ( 152) 621 148.7 1.6e-36 CCDS11578.1 NME1 gene_id:4830|Hs108|chr17 ( 177) 621 148.8 1.7e-36 CCDS11580.1 NME2 gene_id:4831|Hs108|chr17 ( 152) 609 146.0 1e-35 CCDS32682.1 NME2 gene_id:654364|Hs108|chr17 ( 267) 609 146.2 1.5e-35 CCDS73797.1 NME4 gene_id:4833|Hs108|chr16 ( 153) 535 129.2 1.2e-30 CCDS74107.1 NME2 gene_id:4831|Hs108|chr17 ( 82) 328 82.0 1e-16 CCDS44274.1 NME7 gene_id:29922|Hs108|chr1 ( 340) 250 64.9 6.1e-11 CCDS1277.1 NME7 gene_id:29922|Hs108|chr1 ( 376) 250 64.9 6.5e-11 >>CCDS10408.1 NME4 gene_id:4833|Hs108|chr16 (187 aa) initn: 1278 init1: 1278 opt: 1278 Z-score: 1573.8 bits: 297.9 E(32554): 2.4e-81 Smith-Waterman score: 1278; 100.0% identity (100.0% similar) in 187 aa overlap (1-187:1-187) 10 20 30 40 50 60 pF1KB6 MGGLFWRSALRGLRCGPRAPGPSLLVRHGSGGPSWTRERTLVAVKPDGVQRRLVGDVIQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MGGLFWRSALRGLRCGPRAPGPSLLVRHGSGGPSWTRERTLVAVKPDGVQRRLVGDVIQR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 FERRGFTLVGMKMLQAPESVLAEHYQDLRRKPFYPALIRYMSSGPVVAMVWEGYNVVRAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 FERRGFTLVGMKMLQAPESVLAEHYQDLRRKPFYPALIRYMSSGPVVAMVWEGYNVVRAS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 RAMIGHTDSAEAAPGTIRGDFSVHISRNVIHASDSVEGAQREIQLWFQSSELVSWADGGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 RAMIGHTDSAEAAPGTIRGDFSVHISRNVIHASDSVEGAQREIQLWFQSSELVSWADGGQ 130 140 150 160 170 180 pF1KB6 HSSIHPA ::::::: CCDS10 HSSIHPA >>CCDS66886.1 NME4 gene_id:4833|Hs108|chr16 (117 aa) initn: 786 init1: 786 opt: 786 Z-score: 973.2 bits: 186.1 E(32554): 6.9e-48 Smith-Waterman score: 786; 100.0% identity (100.0% similar) in 117 aa overlap (71-187:1-117) 50 60 70 80 90 100 pF1KB6 LVAVKPDGVQRRLVGDVIQRFERRGFTLVGMKMLQAPESVLAEHYQDLRRKPFYPALIRY :::::::::::::::::::::::::::::: CCDS66 MKMLQAPESVLAEHYQDLRRKPFYPALIRY 10 20 30 110 120 130 140 150 160 pF1KB6 MSSGPVVAMVWEGYNVVRASRAMIGHTDSAEAAPGTIRGDFSVHISRNVIHASDSVEGAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 MSSGPVVAMVWEGYNVVRASRAMIGHTDSAEAAPGTIRGDFSVHISRNVIHASDSVEGAQ 40 50 60 70 80 90 170 180 pF1KB6 REIQLWFQSSELVSWADGGQHSSIHPA ::::::::::::::::::::::::::: CCDS66 REIQLWFQSSELVSWADGGQHSSIHPA 100 110 >>CCDS10443.1 NME3 gene_id:4832|Hs108|chr16 (169 aa) initn: 683 init1: 652 opt: 652 Z-score: 806.8 bits: 155.8 E(32554): 1.3e-38 Smith-Waterman score: 652; 61.8% identity (88.9% similar) in 144 aa overlap (38-181:22-165) 10 20 30 40 50 60 pF1KB6 SALRGLRCGPRAPGPSLLVRHGSGGPSWTRERTLVAVKPDGVQRRLVGDVIQRFERRGFT :::..:::::::::::::....::::.:: CCDS10 MICLVLTIFANLFPAACTGAHERTFLAVKPDGVQRRLVGEIVRRFERKGFK 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 LVGMKMLQAPESVLAEHYQDLRRKPFYPALIRYMSSGPVVAMVWEGYNVVRASRAMIGHT ::..:..:: : .: ::: .::..::: :..::.:::::::::.: .:::.:::.:: : CCDS10 LVALKLVQASEELLREHYAELRERPFYGRLVKYMASGPVVAMVWQGLDVVRTSRALIGAT 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 DSAEAAPGTIRGDFSVHISRNVIHASDSVEGAQREIQLWFQSSELVSWADGGQHSSIHPA . :.: :::::::: .....:.::.:::::.:.::: :::...::. : :.. : CCDS10 NPADAPPGTIRGDFCIEVGKNLIHGSDSVESARREIALWFRADELLCWEDSAGHWLYE 120 130 140 150 160 >>CCDS11579.1 NME1 gene_id:4830|Hs108|chr17 (152 aa) initn: 649 init1: 621 opt: 621 Z-score: 769.4 bits: 148.7 E(32554): 1.6e-36 Smith-Waterman score: 621; 58.3% identity (88.9% similar) in 144 aa overlap (38-181:5-148) 10 20 30 40 50 60 pF1KB6 SALRGLRCGPRAPGPSLLVRHGSGGPSWTRERTLVAVKPDGVQRRLVGDVIQRFERRGFT :::..:.::::::: :::..:.:::..:: CCDS11 MANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFR 10 20 30 70 80 90 100 110 120 pF1KB6 LVGMKMLQAPESVLAEHYQDLRRKPFYPALIRYMSSGPVVAMVWEGYNVVRASRAMIGHT :::.:..:: :..: ::: ::. .::. .:..:: ::::::::::: :::...:.:.:.: CCDS11 LVGLKFMQASEDLLKEHYVDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGET 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB6 DSAEAAPGTIRGDFSVHISRNVIHASDSVEGAQREIQLWFQSSELVSWADGGQHSSIHPA . :.. :::::::: ....::.::.:::::.:..:: :::. :::.... .:. CCDS11 NPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIGLWFHPEELVDYTSCAQNWIYE 100 110 120 130 140 150 >>CCDS11578.1 NME1 gene_id:4830|Hs108|chr17 (177 aa) initn: 636 init1: 621 opt: 621 Z-score: 768.5 bits: 148.8 E(32554): 1.7e-36 Smith-Waterman score: 621; 58.3% identity (88.9% similar) in 144 aa overlap (38-181:30-173) 10 20 30 40 50 60 pF1KB6 SALRGLRCGPRAPGPSLLVRHGSGGPSWTRERTLVAVKPDGVQRRLVGDVIQRFERRGFT :::..:.::::::: :::..:.:::..:: CCDS11 MVLLSTLGIVFQGEGPPISSCDTGTMANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFR 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 LVGMKMLQAPESVLAEHYQDLRRKPFYPALIRYMSSGPVVAMVWEGYNVVRASRAMIGHT :::.:..:: :..: ::: ::. .::. .:..:: ::::::::::: :::...:.:.:.: CCDS11 LVGLKFMQASEDLLKEHYVDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGET 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 DSAEAAPGTIRGDFSVHISRNVIHASDSVEGAQREIQLWFQSSELVSWADGGQHSSIHPA . :.. :::::::: ....::.::.:::::.:..:: :::. :::.... .:. CCDS11 NPADSKPGTIRGDFCIQVGRNIIHGSDSVESAEKEIGLWFHPEELVDYTSCAQNWIYE 120 130 140 150 160 170 >>CCDS11580.1 NME2 gene_id:4831|Hs108|chr17 (152 aa) initn: 639 init1: 609 opt: 609 Z-score: 754.7 bits: 146.0 E(32554): 1e-35 Smith-Waterman score: 609; 59.4% identity (89.9% similar) in 138 aa overlap (38-175:5-142) 10 20 30 40 50 60 pF1KB6 SALRGLRCGPRAPGPSLLVRHGSGGPSWTRERTLVAVKPDGVQRRLVGDVIQRFERRGFT :::..:.::::::: :::..:.:::..:: CCDS11 MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFR 10 20 30 70 80 90 100 110 120 pF1KB6 LVGMKMLQAPESVLAEHYQDLRRKPFYPALIRYMSSGPVVAMVWEGYNVVRASRAMIGHT ::.::.:.: : : .:: ::. .::.:.:..::.::::::::::: :::...:.:.:.: CCDS11 LVAMKFLRASEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGET 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB6 DSAEAAPGTIRGDFSVHISRNVIHASDSVEGAQREIQLWFQSSELVSWADGGQHSSIHPA . :.. :::::::: ....::.::.::::..:..::.:::. :::.. CCDS11 NPADSKPGTIRGDFCIQVGRNIIHGSDSVKSAEKEISLWFKPEELVDYKSCAHDWVYE 100 110 120 130 140 150 >>CCDS32682.1 NME2 gene_id:654364|Hs108|chr17 (267 aa) initn: 1093 init1: 609 opt: 609 Z-score: 751.5 bits: 146.2 E(32554): 1.5e-35 Smith-Waterman score: 609; 59.4% identity (89.9% similar) in 138 aa overlap (38-175:120-257) 10 20 30 40 50 60 pF1KB6 SALRGLRCGPRAPGPSLLVRHGSGGPSWTRERTLVAVKPDGVQRRLVGDVIQRFERRGFT :::..:.::::::: :::..:.:::..:: CCDS32 MLGETNPADSKPGTIRGDFCIQVGRTMANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFR 90 100 110 120 130 140 70 80 90 100 110 120 pF1KB6 LVGMKMLQAPESVLAEHYQDLRRKPFYPALIRYMSSGPVVAMVWEGYNVVRASRAMIGHT ::.::.:.: : : .:: ::. .::.:.:..::.::::::::::: :::...:.:.:.: CCDS32 LVAMKFLRASEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMVWEGLNVVKTGRVMLGET 150 160 170 180 190 200 130 140 150 160 170 180 pF1KB6 DSAEAAPGTIRGDFSVHISRNVIHASDSVEGAQREIQLWFQSSELVSWADGGQHSSIHPA . :.. :::::::: ....::.::.::::..:..::.:::. :::.. CCDS32 NPADSKPGTIRGDFCIQVGRNIIHGSDSVKSAEKEISLWFKPEELVDYKSCAHDWVYE 210 220 230 240 250 260 >-- initn: 519 init1: 498 opt: 498 Z-score: 615.4 bits: 121.1 E(32554): 5.9e-28 Smith-Waterman score: 498; 58.9% identity (89.3% similar) in 112 aa overlap (38-149:5-116) 10 20 30 40 50 60 pF1KB6 SALRGLRCGPRAPGPSLLVRHGSGGPSWTRERTLVAVKPDGVQRRLVGDVIQRFERRGFT :::..:.::::::: :::..:.:::..:: CCDS32 MANCERTFIAIKPDGVQRGLVGEIIKRFEQKGFR 10 20 30 70 80 90 100 110 120 pF1KB6 LVGMKMLQAPESVLAEHYQDLRRKPFYPALIRYMSSGPVVAMVWEGYNVVRASRAMIGHT :::.:..:: :..: ::: ::. .::. .:..:: ::::::::::: :::...:.:.:.: CCDS32 LVGLKFMQASEDLLKEHYVDLKDRPFFAGLVKYMHSGPVVAMVWEGLNVVKTGRVMLGET 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB6 DSAEAAPGTIRGDFSVHISRNVIHASDSVEGAQREIQLWFQSSELVSWADGGQHSSIHPA . :.. :::::::: ....:.. CCDS32 NPADSKPGTIRGDFCIQVGRTMANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFRLVAMK 100 110 120 130 140 150 >>CCDS73797.1 NME4 gene_id:4833|Hs108|chr16 (153 aa) initn: 526 init1: 526 opt: 535 Z-score: 663.9 bits: 129.2 E(32554): 1.2e-30 Smith-Waterman score: 972; 81.8% identity (81.8% similar) in 187 aa overlap (1-187:1-153) 10 20 30 40 50 60 pF1KB6 MGGLFWRSALRGLRCGPRAPGPSLLVRHGSGGPSWTRERTLVAVKPDGVQRRLVGDVIQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 MGGLFWRSALRGLRCGPRAPGPSLLVRHGSGGPSWTRERTLVAVKPDGVQRRLVGDVIQR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 FERRGFTLVGMKMLQAPESVLAEHYQDLRRKPFYPALIRYMSSGPVVAMVWEGYNVVRAS ::::::::::::::: ::::::::::: CCDS73 FERRGFTLVGMKMLQ----------------------------------VWEGYNVVRAS 70 80 130 140 150 160 170 180 pF1KB6 RAMIGHTDSAEAAPGTIRGDFSVHISRNVIHASDSVEGAQREIQLWFQSSELVSWADGGQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS73 RAMIGHTDSAEAAPGTIRGDFSVHISRNVIHASDSVEGAQREIQLWFQSSELVSWADGGQ 90 100 110 120 130 140 pF1KB6 HSSIHPA ::::::: CCDS73 HSSIHPA 150 >>CCDS74107.1 NME2 gene_id:4831|Hs108|chr17 (82 aa) initn: 328 init1: 328 opt: 328 Z-score: 413.7 bits: 82.0 E(32554): 1e-16 Smith-Waterman score: 328; 62.5% identity (88.9% similar) in 72 aa overlap (38-109:5-76) 10 20 30 40 50 60 pF1KB6 SALRGLRCGPRAPGPSLLVRHGSGGPSWTRERTLVAVKPDGVQRRLVGDVIQRFERRGFT :::..:.::::::: :::..:.:::..:: CCDS74 MANLERTFIAIKPDGVQRGLVGEIIKRFEQKGFR 10 20 30 70 80 90 100 110 120 pF1KB6 LVGMKMLQAPESVLAEHYQDLRRKPFYPALIRYMSSGPVVAMVWEGYNVVRASRAMIGHT ::.::.:.: : : .:: ::. .::.:.:..::.::::::: CCDS74 LVAMKFLRASEEHLKQHYIDLKDRPFFPGLVKYMNSGPVVAMEHHSWQ 40 50 60 70 80 130 140 150 160 170 180 pF1KB6 DSAEAAPGTIRGDFSVHISRNVIHASDSVEGAQREIQLWFQSSELVSWADGGQHSSIHPA >>CCDS44274.1 NME7 gene_id:29922|Hs108|chr1 (340 aa) initn: 249 init1: 134 opt: 250 Z-score: 309.9 bits: 64.9 E(32554): 6.1e-11 Smith-Waterman score: 250; 29.9% identity (68.6% similar) in 137 aa overlap (37-170:55-189) 10 20 30 40 50 60 pF1KB6 RSALRGLRCGPRAPGPSLLVRHGSGGPSWTRERTLVAVKPDGVQRRLVGDVIQRFERRGF .:.::. .:::.... .:..:. ... :: CCDS44 FIGNKVNVFSRQLVLIDYGDQYTARQLGSRKEKTLALIKPDAISK--AGEIIEIINKAGF 30 40 50 60 70 80 70 80 90 100 110 120 pF1KB6 TLVGMKMLQAPESVLAEHYQDLRRKPFYPALIRYMSSGPVVAMVWEGYNVVRASRAMIGH :.. .::.. .. . . : . .::. ::.....::..:: ... . ..: CCDS44 TITKLKMMMLSRKEALDFHVDHQSRPFFNELIQFITTGPIIAMEILRDDAICEWKRLLGP 90 100 110 120 130 140 130 140 150 160 170 180 pF1KB6 TDSAEA---APGTIRGDFSVHISRNVIHASDSVEGAQREIQLWFQSSELVSWADGGQHSS ..:. : : .::. :.. ::. :. :: .: ::..:.: :: CCDS44 ANSGVARTDASESIRALFGTDGIRNAAHGPDSFASAAREMELFFPSSGGCGPANTAKFTN 150 160 170 180 190 200 pF1KB6 IHPA CCDS44 CTCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDM 210 220 230 240 250 260 187 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 14:10:22 2016 done: Fri Nov 4 14:10:23 2016 Total Scan time: 1.650 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]