FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6863, 179 aa
1>>>pF1KB6863 179 - 179 aa - 179 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8229+/-0.000509; mu= 15.8070+/- 0.032
mean_var=88.7192+/-19.624, 0's: 0 Z-trim(110.1): 217 B-trim: 1120 in 2/50
Lambda= 0.136165
statistics sampled from 18058 (18384) to 18058 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.586), E-opt: 0.2 (0.216), width: 16
Scan time: 4.060
The best scores are: opt bits E(85289)
NP_036229 (OMIM: 608960) ADP-ribosylation factor-l ( 179) 1187 243.2 1.7e-64
NP_848930 (OMIM: 608909) ADP-ribosylation factor-l ( 179) 1010 208.4 5e-54
NP_001032251 (OMIM: 608960) ADP-ribosylation facto ( 142) 941 194.7 5.2e-50
NP_817114 (OMIM: 608960) ADP-ribosylation factor-l ( 142) 941 194.7 5.2e-50
XP_005252458 (OMIM: 608909) PREDICTED: ADP-ribosyl ( 142) 816 170.2 1.3e-42
NP_001019399 (OMIM: 103180) ADP-ribosylation facto ( 181) 607 129.2 3.4e-30
NP_001649 (OMIM: 103180) ADP-ribosylation factor 1 ( 181) 607 129.2 3.4e-30
NP_001019397 (OMIM: 103180) ADP-ribosylation facto ( 181) 607 129.2 3.4e-30
NP_001019398 (OMIM: 103180) ADP-ribosylation facto ( 181) 607 129.2 3.4e-30
NP_001650 (OMIM: 103190) ADP-ribosylation factor 3 ( 181) 598 127.5 1.2e-29
XP_005268913 (OMIM: 103190) PREDICTED: ADP-ribosyl ( 181) 598 127.5 1.2e-29
NP_001168 (OMIM: 603425) ADP-ribosylation factor-l ( 181) 582 124.3 1e-28
NP_001651 (OMIM: 601177) ADP-ribosylation factor 4 ( 180) 569 121.8 6e-28
NP_001653 (OMIM: 103188) ADP-ribosylation factor 5 ( 180) 560 120.0 2.1e-27
NP_001654 (OMIM: 600464) ADP-ribosylation factor 6 ( 175) 550 118.0 7.9e-27
XP_005248554 (OMIM: 601747) PREDICTED: E3 ubiquiti ( 398) 503 109.2 8.1e-24
NP_001647 (OMIM: 601747) E3 ubiquitin-protein liga ( 574) 503 109.4 1e-23
XP_005252457 (OMIM: 608909) PREDICTED: ADP-ribosyl ( 151) 495 107.2 1.3e-23
NP_004302 (OMIM: 604695) ADP-ribosylation factor-l ( 182) 486 105.5 4.9e-23
XP_016871749 (OMIM: 604695) PREDICTED: ADP-ribosyl ( 182) 486 105.5 4.9e-23
NP_001658 (OMIM: 601175) ADP-ribosylation factor-l ( 184) 484 105.1 6.5e-23
NP_079323 (OMIM: 614439) ADP-ribosylation factor-l ( 192) 454 99.2 4e-21
XP_016856722 (OMIM: 103180) PREDICTED: ADP-ribosyl ( 212) 449 98.3 8.4e-21
XP_016864933 (OMIM: 601747) PREDICTED: E3 ubiquiti ( 569) 450 99.0 1.4e-20
NP_150230 (OMIM: 601747) E3 ubiquitin-protein liga ( 569) 450 99.0 1.4e-20
XP_006719454 (OMIM: 103190) PREDICTED: ADP-ribosyl ( 137) 436 95.5 3.7e-20
NP_001287997 (OMIM: 603425) ADP-ribosylation facto ( 135) 434 95.1 4.8e-20
XP_005266310 (OMIM: 609351) PREDICTED: ADP-ribosyl ( 196) 428 94.1 1.4e-19
NP_612459 (OMIM: 609351) ADP-ribosylation factor-l ( 196) 428 94.1 1.4e-19
NP_997625 (OMIM: 604786) ADP-ribosylation factor-l ( 200) 426 93.7 1.9e-19
NP_005729 (OMIM: 604786) ADP-ribosylation factor-l ( 200) 426 93.7 1.9e-19
NP_001032241 (OMIM: 604786) ADP-ribosylation facto ( 200) 426 93.7 1.9e-19
NP_001182325 (OMIM: 604786) ADP-ribosylation facto ( 200) 426 93.7 1.9e-19
NP_001265222 (OMIM: 209900,268000,600151,608845,61 ( 186) 423 93.1 2.7e-19
XP_016862800 (OMIM: 209900,268000,600151,608845,61 ( 186) 423 93.1 2.7e-19
NP_816931 (OMIM: 209900,268000,600151,608845,61357 ( 186) 423 93.1 2.7e-19
NP_115522 (OMIM: 209900,268000,600151,608845,61357 ( 186) 423 93.1 2.7e-19
NP_001310442 (OMIM: 209900,268000,600151,608845,61 ( 193) 420 92.5 4.1e-19
NP_150231 (OMIM: 601747) E3 ubiquitin-protein liga ( 546) 423 93.6 5.4e-19
XP_011526784 (OMIM: 604699) PREDICTED: ADP-ribosyl ( 201) 417 92.0 6.3e-19
NP_003215 (OMIM: 604699) ADP-ribosylation factor-r ( 201) 417 92.0 6.3e-19
XP_016883065 (OMIM: 604699) PREDICTED: ADP-ribosyl ( 201) 417 92.0 6.3e-19
NP_001254476 (OMIM: 604699) ADP-ribosylation facto ( 201) 417 92.0 6.3e-19
XP_011526785 (OMIM: 604699) PREDICTED: ADP-ribosyl ( 201) 417 92.0 6.3e-19
NP_001254477 (OMIM: 604699) ADP-ribosylation facto ( 201) 417 92.0 6.3e-19
NP_005728 (OMIM: 604787) ADP-ribosylation factor-l ( 192) 413 91.2 1.1e-18
NP_001269360 (OMIM: 604787) ADP-ribosylation facto ( 201) 413 91.2 1.1e-18
NP_001254478 (OMIM: 604699) ADP-ribosylation facto ( 173) 370 82.7 3.5e-16
NP_001128230 (OMIM: 604699) ADP-ribosylation facto ( 173) 370 82.7 3.5e-16
XP_011523084 (OMIM: 600732) PREDICTED: ADP-ribosyl ( 201) 370 82.7 3.8e-16
>>NP_036229 (OMIM: 608960) ADP-ribosylation factor-like (179 aa)
initn: 1187 init1: 1187 opt: 1187 Z-score: 1278.8 bits: 243.2 E(85289): 1.7e-64
Smith-Waterman score: 1187; 100.0% identity (100.0% similar) in 179 aa overlap (1-179:1-179)
10 20 30 40 50 60
pF1KB6 MGILFTRIWRLFNHQEHKVIIVGLDNAGKTTILYQFSMNEVVHTSPTIGSNVEEIVINNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MGILFTRIWRLFNHQEHKVIIVGLDNAGKTTILYQFSMNEVVHTSPTIGSNVEEIVINNT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 RFLMWDIGGQESLRSSWNTYYTNTEFVIVVVDSTDRERISVTREELYKMLAHEDLRKAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 RFLMWDIGGQESLRSSWNTYYTNTEFVIVVVDSTDRERISVTREELYKMLAHEDLRKAGL
70 80 90 100 110 120
130 140 150 160 170
pF1KB6 LIFANKQDVKECMTVAEISQFLKLTSIKDHQWHIQACCALTGEGLCQGLEWMMSRLKIR
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LIFANKQDVKECMTVAEISQFLKLTSIKDHQWHIQACCALTGEGLCQGLEWMMSRLKIR
130 140 150 160 170
>>NP_848930 (OMIM: 608909) ADP-ribosylation factor-like (179 aa)
initn: 1010 init1: 1010 opt: 1010 Z-score: 1090.9 bits: 208.4 E(85289): 5e-54
Smith-Waterman score: 1010; 79.9% identity (95.0% similar) in 179 aa overlap (1-179:1-179)
10 20 30 40 50 60
pF1KB6 MGILFTRIWRLFNHQEHKVIIVGLDNAGKTTILYQFSMNEVVHTSPTIGSNVEEIVINNT
::..:...: :: .:::::::::::::::::::::: :::::::::::::::::::..::
NP_848 MGLIFAKLWSLFCNQEHKVIIVGLDNAGKTTILYQFLMNEVVHTSPTIGSNVEEIVVKNT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 RFLMWDIGGQESLRSSWNTYYTNTEFVIVVVDSTDRERISVTREELYKMLAHEDLRKAGL
.::::::::::::::::::::.::::.:.:::: ::::...:.::::.::::::::::..
NP_848 HFLMWDIGGQESLRSSWNTYYSNTEFIILVVDSIDRERLAITKEELYRMLAHEDLRKAAV
70 80 90 100 110 120
130 140 150 160 170
pF1KB6 LIFANKQDVKECMTVAEISQFLKLTSIKDHQWHIQACCALTGEGLCQGLEWMMSRLKIR
::::::::.: :::.::::..: :.::::: ::::.:::::::::::::::: ::. .:
NP_848 LIFANKQDMKGCMTAAEISKYLTLSSIKDHPWHIQSCCALTGEGLCQGLEWMTSRIGVR
130 140 150 160 170
>>NP_001032251 (OMIM: 608960) ADP-ribosylation factor-li (142 aa)
initn: 941 init1: 941 opt: 941 Z-score: 1018.8 bits: 194.7 E(85289): 5.2e-50
Smith-Waterman score: 941; 100.0% identity (100.0% similar) in 142 aa overlap (38-179:1-142)
10 20 30 40 50 60
pF1KB6 IWRLFNHQEHKVIIVGLDNAGKTTILYQFSMNEVVHTSPTIGSNVEEIVINNTRFLMWDI
::::::::::::::::::::::::::::::
NP_001 MNEVVHTSPTIGSNVEEIVINNTRFLMWDI
10 20 30
70 80 90 100 110 120
pF1KB6 GGQESLRSSWNTYYTNTEFVIVVVDSTDRERISVTREELYKMLAHEDLRKAGLLIFANKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGQESLRSSWNTYYTNTEFVIVVVDSTDRERISVTREELYKMLAHEDLRKAGLLIFANKQ
40 50 60 70 80 90
130 140 150 160 170
pF1KB6 DVKECMTVAEISQFLKLTSIKDHQWHIQACCALTGEGLCQGLEWMMSRLKIR
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVKECMTVAEISQFLKLTSIKDHQWHIQACCALTGEGLCQGLEWMMSRLKIR
100 110 120 130 140
>>NP_817114 (OMIM: 608960) ADP-ribosylation factor-like (142 aa)
initn: 941 init1: 941 opt: 941 Z-score: 1018.8 bits: 194.7 E(85289): 5.2e-50
Smith-Waterman score: 941; 100.0% identity (100.0% similar) in 142 aa overlap (38-179:1-142)
10 20 30 40 50 60
pF1KB6 IWRLFNHQEHKVIIVGLDNAGKTTILYQFSMNEVVHTSPTIGSNVEEIVINNTRFLMWDI
::::::::::::::::::::::::::::::
NP_817 MNEVVHTSPTIGSNVEEIVINNTRFLMWDI
10 20 30
70 80 90 100 110 120
pF1KB6 GGQESLRSSWNTYYTNTEFVIVVVDSTDRERISVTREELYKMLAHEDLRKAGLLIFANKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_817 GGQESLRSSWNTYYTNTEFVIVVVDSTDRERISVTREELYKMLAHEDLRKAGLLIFANKQ
40 50 60 70 80 90
130 140 150 160 170
pF1KB6 DVKECMTVAEISQFLKLTSIKDHQWHIQACCALTGEGLCQGLEWMMSRLKIR
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_817 DVKECMTVAEISQFLKLTSIKDHQWHIQACCALTGEGLCQGLEWMMSRLKIR
100 110 120 130 140
>>XP_005252458 (OMIM: 608909) PREDICTED: ADP-ribosylatio (142 aa)
initn: 816 init1: 816 opt: 816 Z-score: 886.1 bits: 170.2 E(85289): 1.3e-42
Smith-Waterman score: 816; 81.0% identity (95.8% similar) in 142 aa overlap (38-179:1-142)
10 20 30 40 50 60
pF1KB6 IWRLFNHQEHKVIIVGLDNAGKTTILYQFSMNEVVHTSPTIGSNVEEIVINNTRFLMWDI
:::::::::::::::::::..::.::::::
XP_005 MNEVVHTSPTIGSNVEEIVVKNTHFLMWDI
10 20 30
70 80 90 100 110 120
pF1KB6 GGQESLRSSWNTYYTNTEFVIVVVDSTDRERISVTREELYKMLAHEDLRKAGLLIFANKQ
::::::::::::::.::::.:.:::: ::::...:.::::.::::::::::..:::::::
XP_005 GGQESLRSSWNTYYSNTEFIILVVDSIDRERLAITKEELYRMLAHEDLRKAAVLIFANKQ
40 50 60 70 80 90
130 140 150 160 170
pF1KB6 DVKECMTVAEISQFLKLTSIKDHQWHIQACCALTGEGLCQGLEWMMSRLKIR
:.: :::.::::..: :.::::: ::::.:::::::::::::::: ::. .:
XP_005 DMKGCMTAAEISKYLTLSSIKDHPWHIQSCCALTGEGLCQGLEWMTSRIGVR
100 110 120 130 140
>>NP_001019399 (OMIM: 103180) ADP-ribosylation factor 1 (181 aa)
initn: 592 init1: 592 opt: 607 Z-score: 663.0 bits: 129.2 E(85289): 3.4e-30
Smith-Waterman score: 607; 48.9% identity (80.9% similar) in 178 aa overlap (1-177:1-178)
10 20 30 40 50
pF1KB6 MGILFTRIWR-LFNHQEHKVIIVGLDNAGKTTILYQFSMNEVVHTSPTIGSNVEEIVINN
:: .:. ... ::...: ....:::: ::::::::.....:.: : :::: ::: . .:
NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 TRFLMWDIGGQESLRSSWNTYYTNTEFVIVVVDSTDRERISVTREELYKMLAHEDLRKAG
: .::.:::...: : :. ::. .: ::::.::::.. .::::..:::...:: :
NP_001 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 LLIFANKQDVKECMTVAEISQFLKLTSIKDHQWHIQACCALTGEGLCQGLEWMMSRLKIR
::.::::::. . :..:::.. : : :.. ..:.::: :: .:.:: .::.:. ..:.
NP_001 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ
130 140 150 160 170 180
NP_001 K
>>NP_001649 (OMIM: 103180) ADP-ribosylation factor 1 [Ho (181 aa)
initn: 592 init1: 592 opt: 607 Z-score: 663.0 bits: 129.2 E(85289): 3.4e-30
Smith-Waterman score: 607; 48.9% identity (80.9% similar) in 178 aa overlap (1-177:1-178)
10 20 30 40 50
pF1KB6 MGILFTRIWR-LFNHQEHKVIIVGLDNAGKTTILYQFSMNEVVHTSPTIGSNVEEIVINN
:: .:. ... ::...: ....:::: ::::::::.....:.: : :::: ::: . .:
NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 TRFLMWDIGGQESLRSSWNTYYTNTEFVIVVVDSTDRERISVTREELYKMLAHEDLRKAG
: .::.:::...: : :. ::. .: ::::.::::.. .::::..:::...:: :
NP_001 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 LLIFANKQDVKECMTVAEISQFLKLTSIKDHQWHIQACCALTGEGLCQGLEWMMSRLKIR
::.::::::. . :..:::.. : : :.. ..:.::: :: .:.:: .::.:. ..:.
NP_001 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ
130 140 150 160 170 180
NP_001 K
>>NP_001019397 (OMIM: 103180) ADP-ribosylation factor 1 (181 aa)
initn: 592 init1: 592 opt: 607 Z-score: 663.0 bits: 129.2 E(85289): 3.4e-30
Smith-Waterman score: 607; 48.9% identity (80.9% similar) in 178 aa overlap (1-177:1-178)
10 20 30 40 50
pF1KB6 MGILFTRIWR-LFNHQEHKVIIVGLDNAGKTTILYQFSMNEVVHTSPTIGSNVEEIVINN
:: .:. ... ::...: ....:::: ::::::::.....:.: : :::: ::: . .:
NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 TRFLMWDIGGQESLRSSWNTYYTNTEFVIVVVDSTDRERISVTREELYKMLAHEDLRKAG
: .::.:::...: : :. ::. .: ::::.::::.. .::::..:::...:: :
NP_001 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 LLIFANKQDVKECMTVAEISQFLKLTSIKDHQWHIQACCALTGEGLCQGLEWMMSRLKIR
::.::::::. . :..:::.. : : :.. ..:.::: :: .:.:: .::.:. ..:.
NP_001 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ
130 140 150 160 170 180
NP_001 K
>>NP_001019398 (OMIM: 103180) ADP-ribosylation factor 1 (181 aa)
initn: 592 init1: 592 opt: 607 Z-score: 663.0 bits: 129.2 E(85289): 3.4e-30
Smith-Waterman score: 607; 48.9% identity (80.9% similar) in 178 aa overlap (1-177:1-178)
10 20 30 40 50
pF1KB6 MGILFTRIWR-LFNHQEHKVIIVGLDNAGKTTILYQFSMNEVVHTSPTIGSNVEEIVINN
:: .:. ... ::...: ....:::: ::::::::.....:.: : :::: ::: . .:
NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 TRFLMWDIGGQESLRSSWNTYYTNTEFVIVVVDSTDRERISVTREELYKMLAHEDLRKAG
: .::.:::...: : :. ::. .: ::::.::::.. .::::..:::...:: :
NP_001 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 LLIFANKQDVKECMTVAEISQFLKLTSIKDHQWHIQACCALTGEGLCQGLEWMMSRLKIR
::.::::::. . :..:::.. : : :.. ..:.::: :: .:.:: .::.:. ..:.
NP_001 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ
130 140 150 160 170 180
NP_001 K
>>NP_001650 (OMIM: 103190) ADP-ribosylation factor 3 [Ho (181 aa)
initn: 588 init1: 588 opt: 598 Z-score: 653.4 bits: 127.5 E(85289): 1.2e-29
Smith-Waterman score: 598; 48.9% identity (79.8% similar) in 178 aa overlap (1-177:1-178)
10 20 30 40 50
pF1KB6 MGILFTRIWR-LFNHQEHKVIIVGLDNAGKTTILYQFSMNEVVHTSPTIGSNVEEIVINN
:: .: . . :....: ....:::: ::::::::.....:.: : :::: ::: . .:
NP_001 MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 TRFLMWDIGGQESLRSSWNTYYTNTEFVIVVVDSTDRERISVTREELYKMLAHEDLRKAG
: .::.:::...: : :. ::. .: ::::.::::.. .::::..:::...:: :
NP_001 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 LLIFANKQDVKECMTVAEISQFLKLTSIKDHQWHIQACCALTGEGLCQGLEWMMSRLKIR
::.::::::. . :..:::.. : : :.. ..:.::: :: .:.:: .::.:. ..::
NP_001 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNK
130 140 150 160 170 180
NP_001 K
179 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 08:10:18 2016 done: Sat Nov 5 08:10:19 2016
Total Scan time: 4.060 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]