Result of FASTA (omim) for pF1KB6864
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6864, 195 aa
  1>>>pF1KB6864 195 - 195 aa - 195 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.9552+/-0.00033; mu= 14.5792+/- 0.021
 mean_var=55.9627+/-11.030, 0's: 0 Z-trim(113.4): 19  B-trim: 0 in 0/55
 Lambda= 0.171445
 statistics sampled from 22734 (22750) to 22734 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.66), E-opt: 0.2 (0.267), width:  16
 Scan time:  3.780

The best scores are:                                      opt bits E(85289)
NP_057130 (OMIM: 606493) exosome complex component ( 195) 1284 325.5 3.4e-89
XP_011538149 (OMIM: 606493) PREDICTED: exosome com ( 160)  943 241.1 7.1e-64
NP_001305291 (OMIM: 606493) exosome complex compon ( 170)  782 201.3 7.3e-52
NP_001305292 (OMIM: 606493) exosome complex compon ( 152)  764 196.8 1.4e-50
NP_001305293 (OMIM: 606493) exosome complex compon ( 129)  536 140.4 1.2e-33
XP_016871793 (OMIM: 606493) PREDICTED: exosome com ( 126)  527 138.1 5.5e-33
NP_001305295 (OMIM: 606493) exosome complex compon ( 109)  525 137.6 6.8e-33
NP_001305294 (OMIM: 606493) exosome complex compon ( 109)  525 137.6 6.8e-33


>>NP_057130 (OMIM: 606493) exosome complex component CSL  (195 aa)
 initn: 1284 init1: 1284 opt: 1284  Z-score: 1722.3  bits: 325.5 E(85289): 3.4e-89
Smith-Waterman score: 1284; 100.0% identity (100.0% similar) in 195 aa overlap (1-195:1-195)

               10        20        30        40        50        60
pF1KB6 MAPPVRYCIPGERLCNLEEGSPGSGTYTRHGYIFSSLAGCLMKSSENGALPVVSVVRETE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MAPPVRYCIPGERLCNLEEGSPGSGTYTRHGYIFSSLAGCLMKSSENGALPVVSVVRETE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 SQLLPDVGAIVTCKVSSINSRFAKVHILYVGSMPLKNSFRGTIRKEDVRATEKDKVEIYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SQLLPDVGAIVTCKVSSINSRFAKVHILYVGSMPLKNSFRGTIRKEDVRATEKDKVEIYK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 SFRPGDIVLAKVISLGDAQSNYLLTTAENELGVVVAHSESGIQMVPISWCEMQCPKTHTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 SFRPGDIVLAKVISLGDAQSNYLLTTAENELGVVVAHSESGIQMVPISWCEMQCPKTHTK
              130       140       150       160       170       180

              190     
pF1KB6 EFRKVARVQPEFLQT
       :::::::::::::::
NP_057 EFRKVARVQPEFLQT
              190     

>>XP_011538149 (OMIM: 606493) PREDICTED: exosome complex  (160 aa)
 initn: 943 init1: 943 opt: 943  Z-score: 1267.8  bits: 241.1 E(85289): 7.1e-64
Smith-Waterman score: 943; 100.0% identity (100.0% similar) in 147 aa overlap (49-195:14-160)

       20        30        40        50        60        70        
pF1KB6 EGSPGSGTYTRHGYIFSSLAGCLMKSSENGALPVVSVVRETESQLLPDVGAIVTCKVSSI
                                     ::::::::::::::::::::::::::::::
XP_011                  MRTQYPIPAQLSPALPVVSVVRETESQLLPDVGAIVTCKVSSI
                                10        20        30        40   

       80        90       100       110       120       130        
pF1KB6 NSRFAKVHILYVGSMPLKNSFRGTIRKEDVRATEKDKVEIYKSFRPGDIVLAKVISLGDA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSRFAKVHILYVGSMPLKNSFRGTIRKEDVRATEKDKVEIYKSFRPGDIVLAKVISLGDA
            50        60        70        80        90       100   

      140       150       160       170       180       190     
pF1KB6 QSNYLLTTAENELGVVVAHSESGIQMVPISWCEMQCPKTHTKEFRKVARVQPEFLQT
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSNYLLTTAENELGVVVAHSESGIQMVPISWCEMQCPKTHTKEFRKVARVQPEFLQT
           110       120       130       140       150       160

>>NP_001305291 (OMIM: 606493) exosome complex component   (170 aa)
 initn: 782 init1: 782 opt: 782  Z-score: 1052.1  bits: 201.3 E(85289): 7.3e-52
Smith-Waterman score: 1068; 87.2% identity (87.2% similar) in 195 aa overlap (1-195:1-170)

               10        20        30        40        50        60
pF1KB6 MAPPVRYCIPGERLCNLEEGSPGSGTYTRHGYIFSSLAGCLMKSSENGALPVVSVVRETE
       :::::::::::::::::::::::::::::::::::::::::::::::::           
NP_001 MAPPVRYCIPGERLCNLEEGSPGSGTYTRHGYIFSSLAGCLMKSSENGA-----------
               10        20        30        40                    

               70        80        90       100       110       120
pF1KB6 SQLLPDVGAIVTCKVSSINSRFAKVHILYVGSMPLKNSFRGTIRKEDVRATEKDKVEIYK
                     ::::::::::::::::::::::::::::::::::::::::::::::
NP_001 --------------VSSINSRFAKVHILYVGSMPLKNSFRGTIRKEDVRATEKDKVEIYK
                    50        60        70        80        90     

              130       140       150       160       170       180
pF1KB6 SFRPGDIVLAKVISLGDAQSNYLLTTAENELGVVVAHSESGIQMVPISWCEMQCPKTHTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFRPGDIVLAKVISLGDAQSNYLLTTAENELGVVVAHSESGIQMVPISWCEMQCPKTHTK
         100       110       120       130       140       150     

              190     
pF1KB6 EFRKVARVQPEFLQT
       :::::::::::::::
NP_001 EFRKVARVQPEFLQT
         160       170

>>NP_001305292 (OMIM: 606493) exosome complex component   (152 aa)
 initn: 1002 init1: 764 opt: 764  Z-score: 1028.8  bits: 196.8 E(85289): 1.4e-50
Smith-Waterman score: 918; 77.4% identity (77.4% similar) in 195 aa overlap (1-195:1-152)

               10        20        30        40        50        60
pF1KB6 MAPPVRYCIPGERLCNLEEGSPGSGTYTRHGYIFSSLAGCLMKSSENGALPVVSVVRETE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAPPVRYCIPGERLCNLEEGSPGSGTYTRHGYIFSSLAGCLMKSSENGALPVVSVVRETE
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 SQLLPDVGAIVTCKVSSINSRFAKVHILYVGSMPLKNSFRGTIRKEDVRATEKDKVEIYK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::    
NP_001 SQLLPDVGAIVTCKVSSINSRFAKVHILYVGSMPLKNSFRGTIRKEDVRATEKDKV----
               70        80        90       100       110          

              130       140       150       160       170       180
pF1KB6 SFRPGDIVLAKVISLGDAQSNYLLTTAENELGVVVAHSESGIQMVPISWCEMQCPKTHTK
                                               ::::::::::::::::::::
NP_001 ---------------------------------------VGIQMVPISWCEMQCPKTHTK
                                               120       130       

              190     
pF1KB6 EFRKVARVQPEFLQT
       :::::::::::::::
NP_001 EFRKVARVQPEFLQT
       140       150  

>>NP_001305293 (OMIM: 606493) exosome complex component   (129 aa)
 initn: 536 init1: 536 opt: 536  Z-score: 725.1  bits: 140.4 E(85289): 1.2e-33
Smith-Waterman score: 729; 66.2% identity (66.2% similar) in 195 aa overlap (1-195:1-129)

               10        20        30        40        50        60
pF1KB6 MAPPVRYCIPGERLCNLEEGSPGSGTYTRHGYIFSSLAGCLMKSSENGALPVVSVVRETE
       :::::::::::::::::::::::::::::::::::::::::::::::::           
NP_001 MAPPVRYCIPGERLCNLEEGSPGSGTYTRHGYIFSSLAGCLMKSSENGA-----------
               10        20        30        40                    

               70        80        90       100       110       120
pF1KB6 SQLLPDVGAIVTCKVSSINSRFAKVHILYVGSMPLKNSFRGTIRKEDVRATEKDKVEIYK
                                                              :::::
NP_001 -------------------------------------------------------VEIYK
                                                             50    

              130       140       150       160       170       180
pF1KB6 SFRPGDIVLAKVISLGDAQSNYLLTTAENELGVVVAHSESGIQMVPISWCEMQCPKTHTK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFRPGDIVLAKVISLGDAQSNYLLTTAENELGVVVAHSESGIQMVPISWCEMQCPKTHTK
           60        70        80        90       100       110    

              190     
pF1KB6 EFRKVARVQPEFLQT
       :::::::::::::::
NP_001 EFRKVARVQPEFLQT
          120         

>>XP_016871793 (OMIM: 606493) PREDICTED: exosome complex  (126 aa)
 initn: 537 init1: 525 opt: 527  Z-score: 713.2  bits: 138.1 E(85289): 5.5e-33
Smith-Waterman score: 527; 74.8% identity (85.4% similar) in 123 aa overlap (82-195:5-126)

              60        70        80          90           100     
pF1KB6 VVSVVRETESQLLPDVGAIVTCKVSSINSRFAKVHIL--YVGSM--P--LKNSFRG-TIR
                                     .:..: :  :.. :  :  :.. :.  . :
XP_016                           MARSLASIHALPKYTSCMWGPCLLRTLFEELSAR
                                         10        20        30    

            110       120       130       140       150       160  
pF1KB6 K--EDVRATEKDKVEIYKSFRPGDIVLAKVISLGDAQSNYLLTTAENELGVVVAHSESGI
       :  :... : .  :::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KMSEQLKKT-RLLVEIYKSFRPGDIVLAKVISLGDAQSNYLLTTAENELGVVVAHSESGI
           40         50        60        70        80        90   

            170       180       190     
pF1KB6 QMVPISWCEMQCPKTHTKEFRKVARVQPEFLQT
       :::::::::::::::::::::::::::::::::
XP_016 QMVPISWCEMQCPKTHTKEFRKVARVQPEFLQT
           100       110       120      

>>NP_001305295 (OMIM: 606493) exosome complex component   (109 aa)
 initn: 537 init1: 525 opt: 525  Z-score: 711.5  bits: 137.6 E(85289): 6.8e-33
Smith-Waterman score: 525; 100.0% identity (100.0% similar) in 80 aa overlap (116-195:30-109)

          90       100       110       120       130       140     
pF1KB6 HILYVGSMPLKNSFRGTIRKEDVRATEKDKVEIYKSFRPGDIVLAKVISLGDAQSNYLLT
                                     ::::::::::::::::::::::::::::::
NP_001  MWGPCLLRTLFEELSARKMSEQLKKTRLLVEIYKSFRPGDIVLAKVISLGDAQSNYLLT
                10        20        30        40        50         

         150       160       170       180       190     
pF1KB6 TAENELGVVVAHSESGIQMVPISWCEMQCPKTHTKEFRKVARVQPEFLQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAENELGVVVAHSESGIQMVPISWCEMQCPKTHTKEFRKVARVQPEFLQT
      60        70        80        90       100         

>>NP_001305294 (OMIM: 606493) exosome complex component   (109 aa)
 initn: 537 init1: 525 opt: 525  Z-score: 711.5  bits: 137.6 E(85289): 6.8e-33
Smith-Waterman score: 525; 100.0% identity (100.0% similar) in 80 aa overlap (116-195:30-109)

          90       100       110       120       130       140     
pF1KB6 HILYVGSMPLKNSFRGTIRKEDVRATEKDKVEIYKSFRPGDIVLAKVISLGDAQSNYLLT
                                     ::::::::::::::::::::::::::::::
NP_001  MWGPCLLRTLFEELSARKMSEQLKKTRLLVEIYKSFRPGDIVLAKVISLGDAQSNYLLT
                10        20        30        40        50         

         150       160       170       180       190     
pF1KB6 TAENELGVVVAHSESGIQMVPISWCEMQCPKTHTKEFRKVARVQPEFLQT
       ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAENELGVVVAHSESGIQMVPISWCEMQCPKTHTKEFRKVARVQPEFLQT
      60        70        80        90       100         




195 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 00:11:47 2016 done: Sat Nov  5 00:11:48 2016
 Total Scan time:  3.780 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]
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