FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6869, 179 aa 1>>>pF1KB6869 179 - 179 aa - 179 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9577+/-0.000332; mu= 14.5958+/- 0.021 mean_var=63.8830+/-12.597, 0's: 0 Z-trim(115.1): 246 B-trim: 1294 in 2/56 Lambda= 0.160466 statistics sampled from 25149 (25417) to 25149 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.686), E-opt: 0.2 (0.298), width: 16 Scan time: 5.700 The best scores are: opt bits E(85289) NP_002253 (OMIM: 602894) natural killer cells anti ( 179) 1242 295.7 2.6e-80 NP_001107868 (OMIM: 602894) natural killer cells a ( 179) 1242 295.7 2.6e-80 XP_016874780 (OMIM: 602894) PREDICTED: natural kil ( 179) 1238 294.8 4.9e-80 XP_016874776 (OMIM: 602894) PREDICTED: natural kil ( 219) 1197 285.4 4.1e-77 XP_016874779 (OMIM: 602894) PREDICTED: natural kil ( 185) 1186 282.8 2.1e-76 XP_006719130 (OMIM: 602894) PREDICTED: natural kil ( 185) 1186 282.8 2.1e-76 XP_016874774 (OMIM: 602894) PREDICTED: natural kil ( 220) 1185 282.6 2.8e-76 XP_011518952 (OMIM: 602894) PREDICTED: natural kil ( 220) 1185 282.6 2.8e-76 XP_016874775 (OMIM: 602894) PREDICTED: natural kil ( 220) 1185 282.6 2.8e-76 XP_011518953 (OMIM: 602894) PREDICTED: natural kil ( 186) 1183 282.1 3.4e-76 NP_031360 (OMIM: 602894) natural killer cells anti ( 148) 1033 247.3 8.1e-66 XP_016874778 (OMIM: 602894) PREDICTED: natural kil ( 188) 992 237.9 7.1e-63 XP_016874777 (OMIM: 602894) PREDICTED: natural kil ( 189) 980 235.1 4.9e-62 NP_002251 (OMIM: 602891) NKG2-C type II integral m ( 231) 313 80.7 1.7e-15 NP_002250 (OMIM: 161555) NKG2-A/NKG2-B type II int ( 233) 311 80.3 2.4e-15 NP_998823 (OMIM: 161555) NKG2-A/NKG2-B type II int ( 233) 311 80.3 2.4e-15 NP_031386 (OMIM: 611817) NKG2-D type II integral m ( 216) 308 79.6 3.7e-15 NP_002252 (OMIM: 602892) NKG2-E type II integral m ( 240) 302 78.2 1e-14 NP_031359 (OMIM: 602892) NKG2-E type II integral m ( 257) 302 78.2 1.1e-14 NP_001291377 (OMIM: 161555) NKG2-A/NKG2-B type II ( 228) 297 77.0 2.2e-14 XP_016874172 (OMIM: 604874) PREDICTED: killer cell ( 199) 278 72.6 4.2e-13 XP_016874174 (OMIM: 604874) PREDICTED: killer cell ( 199) 278 72.6 4.2e-13 XP_016874173 (OMIM: 604874) PREDICTED: killer cell ( 199) 278 72.6 4.2e-13 XP_016874171 (OMIM: 604874) PREDICTED: killer cell ( 199) 278 72.6 4.2e-13 NP_005801 (OMIM: 604874) killer cell lectin-like r ( 189) 276 72.1 5.6e-13 NP_001316028 (OMIM: 604874) killer cell lectin-lik ( 195) 276 72.1 5.7e-13 XP_016874885 (OMIM: 606783) PREDICTED: C-type lect ( 173) 265 69.6 3.1e-12 XP_011518987 (OMIM: 606783) PREDICTED: C-type lect ( 196) 265 69.6 3.4e-12 NP_001092901 (OMIM: 606783) C-type lectin domain f ( 196) 265 69.6 3.4e-12 XP_016874884 (OMIM: 606783) PREDICTED: C-type lect ( 229) 265 69.6 3.8e-12 NP_057593 (OMIM: 606783) C-type lectin domain fami ( 229) 265 69.6 3.8e-12 XP_005253439 (OMIM: 606783) PREDICTED: C-type lect ( 229) 265 69.6 3.8e-12 NP_001772 (OMIM: 107273) early activation antigen ( 199) 264 69.4 4e-12 XP_011518989 (OMIM: 606782) PREDICTED: C-type lect ( 307) 266 70.0 4.1e-12 NP_001284678 (OMIM: 606782) C-type lectin domain f ( 188) 261 68.7 6.2e-12 NP_001284679 (OMIM: 606782) C-type lectin domain f ( 192) 261 68.7 6.3e-12 NP_001284680 (OMIM: 606782) C-type lectin domain f ( 192) 261 68.7 6.3e-12 NP_997228 (OMIM: 612252) C-type lectin domain fami ( 241) 262 69.0 6.4e-12 NP_001284677 (OMIM: 606782) C-type lectin domain f ( 247) 261 68.7 7.7e-12 NP_057595 (OMIM: 606782) C-type lectin domain fami ( 280) 261 68.8 8.5e-12 XP_016867404 (OMIM: 604987) PREDICTED: C-type lect ( 168) 256 67.5 1.3e-11 NP_002534 (OMIM: 602601,608446) oxidized low-densi ( 273) 258 68.1 1.3e-11 NP_001138378 (OMIM: 605872) C-type lectin domain f ( 263) 253 66.9 2.9e-11 NP_998822 (OMIM: 161555) NKG2-A/NKG2-B type II int ( 215) 251 66.4 3.4e-11 NP_015567 (OMIM: 161555) NKG2-A/NKG2-B type II int ( 215) 251 66.4 3.4e-11 NP_001138379 (OMIM: 605872) C-type lectin domain f ( 332) 253 67.0 3.5e-11 XP_006722677 (OMIM: 605872) PREDICTED: C-type lect ( 343) 253 67.0 3.6e-11 NP_001138376 (OMIM: 605872) C-type lectin domain f ( 348) 253 67.0 3.6e-11 NP_001138381 (OMIM: 605872) C-type lectin domain f ( 353) 253 67.0 3.7e-11 XP_006722676 (OMIM: 605872) PREDICTED: C-type lect ( 371) 253 67.0 3.8e-11 >>NP_002253 (OMIM: 602894) natural killer cells antigen (179 aa) initn: 1242 init1: 1242 opt: 1242 Z-score: 1562.9 bits: 295.7 E(85289): 2.6e-80 Smith-Waterman score: 1242; 100.0% identity (100.0% similar) in 179 aa overlap (1-179:1-179) 10 20 30 40 50 60 pF1KB6 MAVFKTTLWRLISGTLGIICLSLMATLGILLKNSFTKLSIEPAFTPGPNIELQKDSDCCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MAVFKTTLWRLISGTLGIICLSLMATLGILLKNSFTKLSIEPAFTPGPNIELQKDSDCCS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 CQEKWVGYRCNCYFISSEQKTWNESRHLCASQKSSLLQLQNTDELDFMSSSQQFYWIGLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 CQEKWVGYRCNCYFISSEQKTWNESRHLCASQKSSLLQLQNTDELDFMSSSQQFYWIGLS 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 YSEEHTAWLWENGSALSQYLFPSFETFNTKNCIAYNPNGNALDESCEDKNRYICKQQLI ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 YSEEHTAWLWENGSALSQYLFPSFETFNTKNCIAYNPNGNALDESCEDKNRYICKQQLI 130 140 150 160 170 >>NP_001107868 (OMIM: 602894) natural killer cells antig (179 aa) initn: 1242 init1: 1242 opt: 1242 Z-score: 1562.9 bits: 295.7 E(85289): 2.6e-80 Smith-Waterman score: 1242; 100.0% identity (100.0% similar) in 179 aa overlap (1-179:1-179) 10 20 30 40 50 60 pF1KB6 MAVFKTTLWRLISGTLGIICLSLMATLGILLKNSFTKLSIEPAFTPGPNIELQKDSDCCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAVFKTTLWRLISGTLGIICLSLMATLGILLKNSFTKLSIEPAFTPGPNIELQKDSDCCS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 CQEKWVGYRCNCYFISSEQKTWNESRHLCASQKSSLLQLQNTDELDFMSSSQQFYWIGLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CQEKWVGYRCNCYFISSEQKTWNESRHLCASQKSSLLQLQNTDELDFMSSSQQFYWIGLS 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 YSEEHTAWLWENGSALSQYLFPSFETFNTKNCIAYNPNGNALDESCEDKNRYICKQQLI ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YSEEHTAWLWENGSALSQYLFPSFETFNTKNCIAYNPNGNALDESCEDKNRYICKQQLI 130 140 150 160 170 >>XP_016874780 (OMIM: 602894) PREDICTED: natural killer (179 aa) initn: 1238 init1: 1238 opt: 1238 Z-score: 1557.9 bits: 294.8 E(85289): 4.9e-80 Smith-Waterman score: 1238; 99.4% identity (100.0% similar) in 179 aa overlap (1-179:1-179) 10 20 30 40 50 60 pF1KB6 MAVFKTTLWRLISGTLGIICLSLMATLGILLKNSFTKLSIEPAFTPGPNIELQKDSDCCS ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::: XP_016 MAVFKTTLWRLISGTLGIICLSLMSTLGILLKNSFTKLSIEPAFTPGPNIELQKDSDCCS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 CQEKWVGYRCNCYFISSEQKTWNESRHLCASQKSSLLQLQNTDELDFMSSSQQFYWIGLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CQEKWVGYRCNCYFISSEQKTWNESRHLCASQKSSLLQLQNTDELDFMSSSQQFYWIGLS 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 YSEEHTAWLWENGSALSQYLFPSFETFNTKNCIAYNPNGNALDESCEDKNRYICKQQLI ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YSEEHTAWLWENGSALSQYLFPSFETFNTKNCIAYNPNGNALDESCEDKNRYICKQQLI 130 140 150 160 170 >>XP_016874776 (OMIM: 602894) PREDICTED: natural killer (219 aa) initn: 1195 init1: 1195 opt: 1197 Z-score: 1505.4 bits: 285.4 E(85289): 4.1e-77 Smith-Waterman score: 1197; 98.3% identity (98.9% similar) in 176 aa overlap (1-176:1-176) 10 20 30 40 50 60 pF1KB6 MAVFKTTLWRLISGTLGIICLSLMATLGILLKNSFTKLSIEPAFTPGPNIELQKDSDCCS ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::: XP_016 MAVFKTTLWRLISGTLGIICLSLMSTLGILLKNSFTKLSIEPAFTPGPNIELQKDSDCCS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 CQEKWVGYRCNCYFISSEQKTWNESRHLCASQKSSLLQLQNTDELDFMSSSQQFYWIGLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CQEKWVGYRCNCYFISSEQKTWNESRHLCASQKSSLLQLQNTDELDFMSSSQQFYWIGLS 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 YSEEHTAWLWENGSALSQYLFPSFETFNTKNCIAYNPNGNALDESCEDKNRYICKQQLI ::::::::::::::::::::::::::::::::::::::::::::::::::::: : XP_016 YSEEHTAWLWENGSALSQYLFPSFETFNTKNCIAYNPNGNALDESCEDKNRYIFLQGWRS 130 140 150 160 170 180 XP_016 LRKLTVMTEGKANTSLYAWQQKGDVLSKRKNTLLLNHQI 190 200 210 >>XP_016874779 (OMIM: 602894) PREDICTED: natural killer (185 aa) initn: 1210 init1: 726 opt: 1186 Z-score: 1492.7 bits: 282.8 E(85289): 2.1e-76 Smith-Waterman score: 1186; 98.3% identity (98.9% similar) in 176 aa overlap (1-175:1-176) 10 20 30 40 50 60 pF1KB6 MAVFKTTLWRLISGTLGIICLSLMATLGILLKNSFTKLSIEPAFTPGPNIELQKDSDCCS ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::: XP_016 MAVFKTTLWRLISGTLGIICLSLMSTLGILLKNSFTKLSIEPAFTPGPNIELQKDSDCCS 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 CQEKWVGYRCNCYFISSEQKTWNESRHLCASQKSSLLQLQNTDEL-DFMSSSQQFYWIGL ::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::: XP_016 CQEKWVGYRCNCYFISSEQKTWNESRHLCASQKSSLLQLQNTDELQDFMSSSQQFYWIGL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 SYSEEHTAWLWENGSALSQYLFPSFETFNTKNCIAYNPNGNALDESCEDKNRYICKQQLI :::::::::::::::::::::::::::::::::::::::::::::::::::::: : XP_016 SYSEEHTAWLWENGSALSQYLFPSFETFNTKNCIAYNPNGNALDESCEDKNRYIYKVLLC 130 140 150 160 170 180 XP_016 CPGWS >>XP_006719130 (OMIM: 602894) PREDICTED: natural killer (185 aa) initn: 1210 init1: 726 opt: 1186 Z-score: 1492.7 bits: 282.8 E(85289): 2.1e-76 Smith-Waterman score: 1186; 98.3% identity (98.9% similar) in 176 aa overlap (1-175:1-176) 10 20 30 40 50 60 pF1KB6 MAVFKTTLWRLISGTLGIICLSLMATLGILLKNSFTKLSIEPAFTPGPNIELQKDSDCCS ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::: XP_006 MAVFKTTLWRLISGTLGIICLSLMSTLGILLKNSFTKLSIEPAFTPGPNIELQKDSDCCS 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 CQEKWVGYRCNCYFISSEQKTWNESRHLCASQKSSLLQLQNTDEL-DFMSSSQQFYWIGL ::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::: XP_006 CQEKWVGYRCNCYFISSEQKTWNESRHLCASQKSSLLQLQNTDELQDFMSSSQQFYWIGL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 SYSEEHTAWLWENGSALSQYLFPSFETFNTKNCIAYNPNGNALDESCEDKNRYICKQQLI :::::::::::::::::::::::::::::::::::::::::::::::::::::: : XP_006 SYSEEHTAWLWENGSALSQYLFPSFETFNTKNCIAYNPNGNALDESCEDKNRYIYKVLLC 130 140 150 160 170 180 XP_006 CPGWS >>XP_016874774 (OMIM: 602894) PREDICTED: natural killer (220 aa) initn: 726 init1: 726 opt: 1185 Z-score: 1490.3 bits: 282.6 E(85289): 2.8e-76 Smith-Waterman score: 1185; 97.7% identity (98.3% similar) in 177 aa overlap (1-176:1-177) 10 20 30 40 50 60 pF1KB6 MAVFKTTLWRLISGTLGIICLSLMATLGILLKNSFTKLSIEPAFTPGPNIELQKDSDCCS ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::: XP_016 MAVFKTTLWRLISGTLGIICLSLMSTLGILLKNSFTKLSIEPAFTPGPNIELQKDSDCCS 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 CQEKWVGYRCNCYFISSEQKTWNESRHLCASQKSSLLQLQNTDEL-DFMSSSQQFYWIGL ::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::: XP_016 CQEKWVGYRCNCYFISSEQKTWNESRHLCASQKSSLLQLQNTDELQDFMSSSQQFYWIGL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 SYSEEHTAWLWENGSALSQYLFPSFETFNTKNCIAYNPNGNALDESCEDKNRYICKQQLI :::::::::::::::::::::::::::::::::::::::::::::::::::::: : XP_016 SYSEEHTAWLWENGSALSQYLFPSFETFNTKNCIAYNPNGNALDESCEDKNRYIFLQGWR 130 140 150 160 170 180 XP_016 SLRKLTVMTEGKANTSLYAWQQKGDVLSKRKNTLLLNHQI 190 200 210 220 >>XP_011518952 (OMIM: 602894) PREDICTED: natural killer (220 aa) initn: 726 init1: 726 opt: 1185 Z-score: 1490.3 bits: 282.6 E(85289): 2.8e-76 Smith-Waterman score: 1185; 97.7% identity (98.3% similar) in 177 aa overlap (1-176:1-177) 10 20 30 40 50 60 pF1KB6 MAVFKTTLWRLISGTLGIICLSLMATLGILLKNSFTKLSIEPAFTPGPNIELQKDSDCCS ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::: XP_011 MAVFKTTLWRLISGTLGIICLSLMSTLGILLKNSFTKLSIEPAFTPGPNIELQKDSDCCS 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 CQEKWVGYRCNCYFISSEQKTWNESRHLCASQKSSLLQLQNTDEL-DFMSSSQQFYWIGL ::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::: XP_011 CQEKWVGYRCNCYFISSEQKTWNESRHLCASQKSSLLQLQNTDELQDFMSSSQQFYWIGL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 SYSEEHTAWLWENGSALSQYLFPSFETFNTKNCIAYNPNGNALDESCEDKNRYICKQQLI :::::::::::::::::::::::::::::::::::::::::::::::::::::: : XP_011 SYSEEHTAWLWENGSALSQYLFPSFETFNTKNCIAYNPNGNALDESCEDKNRYIFLQGWR 130 140 150 160 170 180 XP_011 SLRKLTVMTEGKANTSLYAWQQKGDVLSKRKNTLLLNHQI 190 200 210 220 >>XP_016874775 (OMIM: 602894) PREDICTED: natural killer (220 aa) initn: 726 init1: 726 opt: 1185 Z-score: 1490.3 bits: 282.6 E(85289): 2.8e-76 Smith-Waterman score: 1185; 97.7% identity (98.3% similar) in 177 aa overlap (1-176:1-177) 10 20 30 40 50 60 pF1KB6 MAVFKTTLWRLISGTLGIICLSLMATLGILLKNSFTKLSIEPAFTPGPNIELQKDSDCCS ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::: XP_016 MAVFKTTLWRLISGTLGIICLSLMSTLGILLKNSFTKLSIEPAFTPGPNIELQKDSDCCS 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 CQEKWVGYRCNCYFISSEQKTWNESRHLCASQKSSLLQLQNTDEL-DFMSSSQQFYWIGL ::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::: XP_016 CQEKWVGYRCNCYFISSEQKTWNESRHLCASQKSSLLQLQNTDELQDFMSSSQQFYWIGL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 SYSEEHTAWLWENGSALSQYLFPSFETFNTKNCIAYNPNGNALDESCEDKNRYICKQQLI :::::::::::::::::::::::::::::::::::::::::::::::::::::: : XP_016 SYSEEHTAWLWENGSALSQYLFPSFETFNTKNCIAYNPNGNALDESCEDKNRYIFLQGWR 130 140 150 160 170 180 XP_016 SLRKLTVMTEGKANTSLYAWQQKGDVLSKRKNTLLLNHQI 190 200 210 220 >>XP_011518953 (OMIM: 602894) PREDICTED: natural killer (186 aa) initn: 740 init1: 726 opt: 1183 Z-score: 1488.9 bits: 282.1 E(85289): 3.4e-76 Smith-Waterman score: 1183; 98.9% identity (99.4% similar) in 174 aa overlap (1-173:1-174) 10 20 30 40 50 60 pF1KB6 MAVFKTTLWRLISGTLGIICLSLMATLGILLKNSFTKLSIEPAFTPGPNIELQKDSDCCS ::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::: XP_011 MAVFKTTLWRLISGTLGIICLSLMSTLGILLKNSFTKLSIEPAFTPGPNIELQKDSDCCS 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 CQEKWVGYRCNCYFISSEQKTWNESRHLCASQKSSLLQLQNTDEL-DFMSSSQQFYWIGL ::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::: XP_011 CQEKWVGYRCNCYFISSEQKTWNESRHLCASQKSSLLQLQNTDELQDFMSSSQQFYWIGL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 SYSEEHTAWLWENGSALSQYLFPSFETFNTKNCIAYNPNGNALDESCEDKNRYICKQQLI :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SYSEEHTAWLWENGSALSQYLFPSFETFNTKNCIAYNPNGNALDESCEDKNRYIYYLIWG 130 140 150 160 170 180 XP_011 KPVIMS 179 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:08:27 2016 done: Sat Nov 5 04:08:28 2016 Total Scan time: 5.700 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]