FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6871, 180 aa 1>>>pF1KB6871 180 - 180 aa - 180 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9607+/-0.000433; mu= 15.5889+/- 0.027 mean_var=82.8678+/-17.732, 0's: 0 Z-trim(112.9): 249 B-trim: 2110 in 3/50 Lambda= 0.140890 statistics sampled from 21611 (21998) to 21611 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.637), E-opt: 0.2 (0.258), width: 16 Scan time: 5.510 The best scores are: opt bits E(85289) NP_001653 (OMIM: 103188) ADP-ribosylation factor 5 ( 180) 1189 251.0 7.4e-67 NP_001651 (OMIM: 601177) ADP-ribosylation factor 4 ( 180) 1096 232.1 3.6e-61 NP_001019399 (OMIM: 103180) ADP-ribosylation facto ( 181) 972 206.9 1.4e-53 NP_001649 (OMIM: 103180) ADP-ribosylation factor 1 ( 181) 972 206.9 1.4e-53 NP_001019397 (OMIM: 103180) ADP-ribosylation facto ( 181) 972 206.9 1.4e-53 NP_001019398 (OMIM: 103180) ADP-ribosylation facto ( 181) 972 206.9 1.4e-53 NP_001650 (OMIM: 103190) ADP-ribosylation factor 3 ( 181) 957 203.9 1.2e-52 XP_005268913 (OMIM: 103190) PREDICTED: ADP-ribosyl ( 181) 957 203.9 1.2e-52 NP_001654 (OMIM: 600464) ADP-ribosylation factor 6 ( 175) 809 173.8 1.3e-43 XP_016856722 (OMIM: 103180) PREDICTED: ADP-ribosyl ( 212) 719 155.6 4.8e-38 NP_001168 (OMIM: 603425) ADP-ribosylation factor-l ( 181) 711 153.9 1.3e-37 XP_006719454 (OMIM: 103190) PREDICTED: ADP-ribosyl ( 137) 705 152.5 2.5e-37 XP_005248554 (OMIM: 601747) PREDICTED: E3 ubiquiti ( 398) 671 146.1 6.4e-35 NP_001647 (OMIM: 601747) E3 ubiquitin-protein liga ( 574) 671 146.3 8.3e-35 XP_016864933 (OMIM: 601747) PREDICTED: E3 ubiquiti ( 569) 590 129.8 7.4e-30 NP_150230 (OMIM: 601747) E3 ubiquitin-protein liga ( 569) 590 129.8 7.4e-30 NP_036229 (OMIM: 608960) ADP-ribosylation factor-l ( 179) 560 123.2 2.3e-28 NP_848930 (OMIM: 608909) ADP-ribosylation factor-l ( 179) 559 123.0 2.6e-28 NP_150231 (OMIM: 601747) E3 ubiquitin-protein liga ( 546) 562 124.1 3.7e-28 NP_001658 (OMIM: 601175) ADP-ribosylation factor-l ( 184) 547 120.6 1.4e-27 NP_079323 (OMIM: 614439) ADP-ribosylation factor-l ( 192) 538 118.7 5.3e-27 XP_016871749 (OMIM: 604695) PREDICTED: ADP-ribosyl ( 182) 531 117.3 1.4e-26 NP_004302 (OMIM: 604695) ADP-ribosylation factor-l ( 182) 531 117.3 1.4e-26 NP_005728 (OMIM: 604787) ADP-ribosylation factor-l ( 192) 519 114.9 7.7e-26 NP_001269360 (OMIM: 604787) ADP-ribosylation facto ( 201) 519 114.9 7.9e-26 NP_001287997 (OMIM: 603425) ADP-ribosylation facto ( 135) 502 111.3 6.6e-25 NP_001032241 (OMIM: 604786) ADP-ribosylation facto ( 200) 499 110.8 1.3e-24 NP_005729 (OMIM: 604786) ADP-ribosylation factor-l ( 200) 499 110.8 1.3e-24 NP_001182325 (OMIM: 604786) ADP-ribosylation facto ( 200) 499 110.8 1.3e-24 NP_997625 (OMIM: 604786) ADP-ribosylation factor-l ( 200) 499 110.8 1.3e-24 XP_011523084 (OMIM: 600732) PREDICTED: ADP-ribosyl ( 201) 465 103.9 1.6e-22 NP_001652 (OMIM: 600732) ADP-ribosylation factor-l ( 201) 465 103.9 1.6e-22 XP_005252458 (OMIM: 608909) PREDICTED: ADP-ribosyl ( 142) 449 100.5 1.2e-21 XP_005266310 (OMIM: 609351) PREDICTED: ADP-ribosyl ( 196) 450 100.9 1.3e-21 NP_612459 (OMIM: 609351) ADP-ribosylation factor-l ( 196) 450 100.9 1.3e-21 NP_001032251 (OMIM: 608960) ADP-ribosylation facto ( 142) 448 100.3 1.4e-21 NP_817114 (OMIM: 608960) ADP-ribosylation factor-l ( 142) 448 100.3 1.4e-21 NP_816931 (OMIM: 209900,268000,600151,608845,61357 ( 186) 428 96.4 2.8e-20 NP_001265222 (OMIM: 209900,268000,600151,608845,61 ( 186) 428 96.4 2.8e-20 NP_115522 (OMIM: 209900,268000,600151,608845,61357 ( 186) 428 96.4 2.8e-20 XP_016862800 (OMIM: 209900,268000,600151,608845,61 ( 186) 428 96.4 2.8e-20 NP_001310442 (OMIM: 209900,268000,600151,608845,61 ( 193) 426 96.0 3.8e-20 NP_060654 (OMIM: 616596) ADP-ribosylation factor-l ( 186) 387 88.0 9e-18 NP_620150 (OMIM: 616597) ADP-ribosylation factor-l ( 186) 375 85.6 4.9e-17 NP_001186674 (OMIM: 601175) ADP-ribosylation facto ( 157) 367 83.9 1.3e-16 NP_001310443 (OMIM: 209900,268000,600151,608845,61 ( 159) 361 82.7 3.1e-16 XP_016862801 (OMIM: 209900,268000,600151,608845,61 ( 159) 361 82.7 3.1e-16 NP_003215 (OMIM: 604699) ADP-ribosylation factor-r ( 201) 350 80.6 1.7e-15 NP_001254476 (OMIM: 604699) ADP-ribosylation facto ( 201) 350 80.6 1.7e-15 XP_011526784 (OMIM: 604699) PREDICTED: ADP-ribosyl ( 201) 350 80.6 1.7e-15 >>NP_001653 (OMIM: 103188) ADP-ribosylation factor 5 [Ho (180 aa) initn: 1189 init1: 1189 opt: 1189 Z-score: 1321.3 bits: 251.0 E(85289): 7.4e-67 Smith-Waterman score: 1189; 100.0% identity (100.0% similar) in 180 aa overlap (1-180:1-180) 10 20 30 40 50 60 pF1KB6 MGLTVSALFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGLTVSALFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LLVFANKQDMPNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGLYDGLDWLSHELSKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLVFANKQDMPNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGLYDGLDWLSHELSKR 130 140 150 160 170 180 >>NP_001651 (OMIM: 601177) ADP-ribosylation factor 4 [Ho (180 aa) initn: 1096 init1: 1096 opt: 1096 Z-score: 1219.1 bits: 232.1 E(85289): 3.6e-61 Smith-Waterman score: 1096; 90.0% identity (97.2% similar) in 180 aa overlap (1-180:1-180) 10 20 30 40 50 60 pF1KB6 MGLTVSALFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN ::::.:.::::.:::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAV ::::::::::::.:::::.::::::::::::::::::::.:: :::::::: ::::::: NP_001 ICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVADELQKMLLVDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LLVFANKQDMPNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGLYDGLDWLSHELSKR ::.::::::.:::: .::.::::::: ::.:::::::::::::::::.::::::.::::: NP_001 LLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR 130 140 150 160 170 180 >>NP_001019399 (OMIM: 103180) ADP-ribosylation factor 1 (181 aa) initn: 972 init1: 972 opt: 972 Z-score: 1082.9 bits: 206.9 E(85289): 1.4e-53 Smith-Waterman score: 972; 81.9% identity (93.2% similar) in 177 aa overlap (1-177:1-177) 10 20 30 40 50 60 pF1KB6 MGLTVSALFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :: . ::. .::::.::::::::::::::::::::::::::::::::::::::::::: NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAV : ::::::::::::::::::::::::::::::::::::::.:. .::..:: :::::::: NP_001 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LLVFANKQDMPNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGLYDGLDWLSHELSKR :::::::::.:::: ..:.::::::. :: :.::.::::::.: :::.::::::..: NP_001 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ 130 140 150 160 170 180 NP_001 K >>NP_001649 (OMIM: 103180) ADP-ribosylation factor 1 [Ho (181 aa) initn: 972 init1: 972 opt: 972 Z-score: 1082.9 bits: 206.9 E(85289): 1.4e-53 Smith-Waterman score: 972; 81.9% identity (93.2% similar) in 177 aa overlap (1-177:1-177) 10 20 30 40 50 60 pF1KB6 MGLTVSALFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :: . ::. .::::.::::::::::::::::::::::::::::::::::::::::::: NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAV : ::::::::::::::::::::::::::::::::::::::.:. .::..:: :::::::: NP_001 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LLVFANKQDMPNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGLYDGLDWLSHELSKR :::::::::.:::: ..:.::::::. :: :.::.::::::.: :::.::::::..: NP_001 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ 130 140 150 160 170 180 NP_001 K >>NP_001019397 (OMIM: 103180) ADP-ribosylation factor 1 (181 aa) initn: 972 init1: 972 opt: 972 Z-score: 1082.9 bits: 206.9 E(85289): 1.4e-53 Smith-Waterman score: 972; 81.9% identity (93.2% similar) in 177 aa overlap (1-177:1-177) 10 20 30 40 50 60 pF1KB6 MGLTVSALFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :: . ::. .::::.::::::::::::::::::::::::::::::::::::::::::: NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAV : ::::::::::::::::::::::::::::::::::::::.:. .::..:: :::::::: NP_001 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LLVFANKQDMPNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGLYDGLDWLSHELSKR :::::::::.:::: ..:.::::::. :: :.::.::::::.: :::.::::::..: NP_001 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ 130 140 150 160 170 180 NP_001 K >>NP_001019398 (OMIM: 103180) ADP-ribosylation factor 1 (181 aa) initn: 972 init1: 972 opt: 972 Z-score: 1082.9 bits: 206.9 E(85289): 1.4e-53 Smith-Waterman score: 972; 81.9% identity (93.2% similar) in 177 aa overlap (1-177:1-177) 10 20 30 40 50 60 pF1KB6 MGLTVSALFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :: . ::. .::::.::::::::::::::::::::::::::::::::::::::::::: NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAV : ::::::::::::::::::::::::::::::::::::::.:. .::..:: :::::::: NP_001 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LLVFANKQDMPNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGLYDGLDWLSHELSKR :::::::::.:::: ..:.::::::. :: :.::.::::::.: :::.::::::..: NP_001 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ 130 140 150 160 170 180 NP_001 K >>NP_001650 (OMIM: 103190) ADP-ribosylation factor 3 [Ho (181 aa) initn: 957 init1: 957 opt: 957 Z-score: 1066.4 bits: 203.9 E(85289): 1.2e-52 Smith-Waterman score: 957; 78.9% identity (93.3% similar) in 180 aa overlap (1-180:1-180) 10 20 30 40 50 60 pF1KB6 MGLTVSALFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :: . :.. ..:::.::::::::::::::::::::::::::::::::::::::::::: NP_001 MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAV : ::::::::::::::::::::::::::::::::::::::.:. .::..:: :::::::: NP_001 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LLVFANKQDMPNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGLYDGLDWLSHELSKR :::::::::.:::: ..:.::::::. :: :.::.::::::.: :::.:::::...:... NP_001 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNK 130 140 150 160 170 180 NP_001 K >>XP_005268913 (OMIM: 103190) PREDICTED: ADP-ribosylatio (181 aa) initn: 957 init1: 957 opt: 957 Z-score: 1066.4 bits: 203.9 E(85289): 1.2e-52 Smith-Waterman score: 957; 78.9% identity (93.3% similar) in 180 aa overlap (1-180:1-180) 10 20 30 40 50 60 pF1KB6 MGLTVSALFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :: . :.. ..:::.::::::::::::::::::::::::::::::::::::::::::: XP_005 MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAV : ::::::::::::::::::::::::::::::::::::::.:. .::..:: :::::::: XP_005 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LLVFANKQDMPNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGLYDGLDWLSHELSKR :::::::::.:::: ..:.::::::. :: :.::.::::::.: :::.:::::...:... XP_005 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNK 130 140 150 160 170 180 XP_005 K >>NP_001654 (OMIM: 600464) ADP-ribosylation factor 6 [Ho (175 aa) initn: 840 init1: 799 opt: 809 Z-score: 904.0 bits: 173.8 E(85289): 1.3e-43 Smith-Waterman score: 809; 67.1% identity (90.4% similar) in 167 aa overlap (8-174:4-170) 10 20 30 40 50 60 pF1KB6 MGLTVSALFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN ..:.:::.:.:::::.:::::::::::::::::. ::::::.::::::: ::: NP_001 MGKVLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKN 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 ICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAV . :.:::::::::::::::::. .::::::::: ::.:..:. .::...... :.:::. NP_001 VKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAI 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 LLVFANKQDMPNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGLYDGLDWLSHELSKR .:.::::::.:.:: :. .:::: ..:.:.:::: .:::.: :::.:: ::. NP_001 ILIFANKQDLPDAMKPHEIQEKLGLTRIRDRNWYVQPSCATSGDGLYEGLTWLTSNYKS 120 130 140 150 160 170 >>XP_016856722 (OMIM: 103180) PREDICTED: ADP-ribosylatio (212 aa) initn: 719 init1: 719 opt: 719 Z-score: 804.1 bits: 155.6 E(85289): 4.8e-38 Smith-Waterman score: 719; 86.7% identity (93.8% similar) in 128 aa overlap (1-128:1-128) 10 20 30 40 50 60 pF1KB6 MGLTVSALFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :: . ::. .::::.::::::::::::::::::::::::::::::::::::::::::: XP_016 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAV : ::::::::::::::::::::::::::::::::::::::.:. .::..:: :::::::: XP_016 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LLVFANKQDMPNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGLYDGLDWLSHELSKR :::::::: XP_016 LLVFANKQVGARASLGNVRSQCGFRLVVGVTGGWWGPFLCPVDSPSHQPFLPPGPPQRHE 130 140 150 160 170 180 180 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 14:11:27 2016 done: Fri Nov 4 14:11:28 2016 Total Scan time: 5.510 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]