FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6872, 198 aa 1>>>pF1KB6872 198 - 198 aa - 198 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.7430+/-0.00109; mu= 16.3655+/- 0.067 mean_var=74.5510+/-15.977, 0's: 0 Z-trim(104.5): 129 B-trim: 557 in 2/48 Lambda= 0.148541 statistics sampled from 7760 (7924) to 7760 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.621), E-opt: 0.2 (0.243), width: 16 Scan time: 1.590 The best scores are: opt bits E(32554) CCDS7298.1 SAR1A gene_id:56681|Hs108|chr10 ( 198) 1306 289.1 1.2e-78 CCDS4177.1 SAR1B gene_id:51128|Hs108|chr5 ( 198) 1215 269.6 8.7e-73 CCDS9695.1 ARF6 gene_id:382|Hs108|chr14 ( 175) 316 76.9 7.9e-15 CCDS43322.1 TRIM23 gene_id:373|Hs108|chr5 ( 569) 308 75.7 6e-14 CCDS9419.1 ARL11 gene_id:115761|Hs108|chr13 ( 196) 302 74.0 6.9e-14 CCDS8088.1 ARL2 gene_id:402|Hs108|chr11 ( 184) 298 73.1 1.2e-13 CCDS2928.1 ARL6 gene_id:84100|Hs108|chr3 ( 186) 297 72.9 1.4e-13 CCDS3986.1 TRIM23 gene_id:373|Hs108|chr5 ( 546) 302 74.4 1.4e-13 CCDS3192.1 ARL14 gene_id:80117|Hs108|chr3 ( 192) 297 72.9 1.4e-13 CCDS3987.1 TRIM23 gene_id:373|Hs108|chr5 ( 574) 302 74.4 1.5e-13 CCDS1565.1 ARF1 gene_id:375|Hs108|chr1 ( 181) 295 72.4 1.8e-13 CCDS8774.1 ARF3 gene_id:377|Hs108|chr12 ( 181) 294 72.2 2.1e-13 CCDS11463.1 ARL4D gene_id:379|Hs108|chr17 ( 201) 291 71.6 3.6e-13 CCDS34745.1 ARF5 gene_id:381|Hs108|chr7 ( 180) 282 69.6 1.3e-12 CCDS7538.1 ARL3 gene_id:403|Hs108|chr10 ( 182) 281 69.4 1.5e-12 CCDS5359.1 ARL4A gene_id:10124|Hs108|chr7 ( 200) 276 68.4 3.3e-12 CCDS2566.1 ARL8B gene_id:55207|Hs108|chr3 ( 186) 269 66.9 8.9e-12 CCDS2884.1 ARF4 gene_id:378|Hs108|chr3 ( 180) 268 66.6 1e-11 CCDS1421.1 ARL8A gene_id:127829|Hs108|chr1 ( 186) 267 66.4 1.2e-11 CCDS44958.1 ARL1 gene_id:400|Hs108|chr12 ( 181) 266 66.2 1.4e-11 CCDS2925.1 ARL13B gene_id:200894|Hs108|chr3 ( 428) 262 65.7 4.5e-11 CCDS2512.1 ARL4C gene_id:10123|Hs108|chr2 ( 192) 256 64.1 6.3e-11 CCDS63169.1 ARL4C gene_id:10123|Hs108|chr2 ( 201) 256 64.1 6.5e-11 >>CCDS7298.1 SAR1A gene_id:56681|Hs108|chr10 (198 aa) initn: 1306 init1: 1306 opt: 1306 Z-score: 1525.6 bits: 289.1 E(32554): 1.2e-78 Smith-Waterman score: 1306; 100.0% identity (100.0% similar) in 198 aa overlap (1-198:1-198) 10 20 30 40 50 60 pF1KB6 MSFIFEWIYNGFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 MSFIFEWIYNGFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 SEELTIAGMTFTTFDLGGHEQARRVWKNYLPAINGIVFLVDCADHSRLVESKVELNALMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 SEELTIAGMTFTTFDLGGHEQARRVWKNYLPAINGIVFLVDCADHSRLVESKVELNALMT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 DETISNVPILILGNKIDRTDAISEEKLREIFGLYGQTTGKGNVTLKELNARPMEVFMCSV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS72 DETISNVPILILGNKIDRTDAISEEKLREIFGLYGQTTGKGNVTLKELNARPMEVFMCSV 130 140 150 160 170 180 190 pF1KB6 LKRQGYGEGFRWLSQYID :::::::::::::::::: CCDS72 LKRQGYGEGFRWLSQYID 190 >>CCDS4177.1 SAR1B gene_id:51128|Hs108|chr5 (198 aa) initn: 1215 init1: 1215 opt: 1215 Z-score: 1420.2 bits: 269.6 E(32554): 8.7e-73 Smith-Waterman score: 1215; 89.9% identity (98.0% similar) in 198 aa overlap (1-198:1-198) 10 20 30 40 50 60 pF1KB6 MSFIFEWIYNGFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPT :::::.:::.::::::::::::::.::::::::::::::::::::::::::::::::::: CCDS41 MSFIFDWIYSGFSSVLQFLGLYKKTGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 SEELTIAGMTFTTFDLGGHEQARRVWKNYLPAINGIVFLVDCADHSRLVESKVELNALMT ::::::::::::::::::: ::::::::::::::::::::::::: ::.::: ::..::: CCDS41 SEELTIAGMTFTTFDLGGHVQARRVWKNYLPAINGIVFLVDCADHERLLESKEELDSLMT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 DETISNVPILILGNKIDRTDAISEEKLREIFGLYGQTTGKGNVTLKELNARPMEVFMCSV ::::.::::::::::::: .:::::.:::.:::::::::::...::::::::.::::::: CCDS41 DETIANVPILILGNKIDRPEAISEERLREMFGLYGQTTGKGSISLKELNARPLEVFMCSV 130 140 150 160 170 180 190 pF1KB6 LKRQGYGEGFRWLSQYID ::::::::::::..:::: CCDS41 LKRQGYGEGFRWMAQYID 190 >>CCDS9695.1 ARF6 gene_id:382|Hs108|chr14 (175 aa) initn: 336 init1: 314 opt: 316 Z-score: 379.7 bits: 76.9 E(32554): 7.9e-15 Smith-Waterman score: 317; 33.3% identity (67.2% similar) in 174 aa overlap (24-194:12-170) 10 20 30 40 50 pF1KB6 MSFIFEWIYNGFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHV---PTL : ....:::: :::::.:. :: ::: : ::. CCDS96 MGKVLSKIFGNKEMRILMLGLDAAGKTTILYKLK---LGQSVTTIPTV 10 20 30 40 60 70 80 90 100 110 pF1KB6 HPTSEELTIAGMTFTTFDLGGHEQARRVWKNYLPAINGIVFLVDCADHSRLVESKVELNA . : .: .. :...:.::... : .:..: . .:..:.:::::..:. :.. ::. CCDS96 GFNVETVTYKNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHR 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB6 LMTDETISNVPILILGNKIDRTDAISEEKLREIFGLYGQTTGKGNVTLKELNARPMEVFM ...:. . .. :::..:: : ::.. ....: .:: . .. ..: CCDS96 IINDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLT-------RIRDRNWYVQPS---- 110 120 130 140 150 180 190 pF1KB6 CSVLKRQGYGEGFRWLSQYID :.. . .: ::. ::. CCDS96 CAT-SGDGLYEGLTWLTSNYKS 160 170 >>CCDS43322.1 TRIM23 gene_id:373|Hs108|chr5 (569 aa) initn: 290 init1: 290 opt: 308 Z-score: 363.9 bits: 75.7 E(32554): 6e-14 Smith-Waterman score: 308; 33.6% identity (69.7% similar) in 152 aa overlap (27-178:406-556) 10 20 30 40 50 pF1KB6 MSFIFEWIYNGFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPT ..: ::::.:::::.: ::.:.. : .:: CCDS43 EVADHIQLDASIPVTFTKDNRVHIGPKMEIRVVTLGLDGAGKTTILFKLKQDEFMQPIPT 380 390 400 410 420 430 60 70 80 90 100 110 pF1KB6 LHPTSEELTIAGMTFTTFDLGGHEQARRVWKNYLPAINGIVFLVDCADHSRLVESKVELN . . : . .. :: .:.::... : .::.: ...::.:: . ..:. :.. :: CCDS43 IGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVDSSHRDRISEAHSELA 440 450 460 470 480 490 120 130 140 150 160 170 pF1KB6 ALMTDETISNVPILILGNKIDRTDAISEEKLREIFGLYGQTTGKGNVTLKELNARPMEVF :.:.. . .. .::..:: : . :.: :.. :...:. :. . .. .:: . . CCDS43 KLLTEKELRDALLLIFANKQDVAGALSVEEITELLSLHKLCCGR-SWYIQGCDARSVFQI 500 510 520 530 540 550 180 190 pF1KB6 MCSVLKRQGYGEGFRWLSQYID .: CCDS43 ICDQYTGKEVVTEKG 560 >>CCDS9419.1 ARL11 gene_id:115761|Hs108|chr13 (196 aa) initn: 248 init1: 173 opt: 302 Z-score: 362.8 bits: 74.0 E(32554): 6.9e-14 Smith-Waterman score: 304; 32.9% identity (66.5% similar) in 173 aa overlap (22-193:9-169) 10 20 30 40 50 60 pF1KB6 MSFIFEWIYNGFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPT .: ...:..:::.:::::::. :: .: . .::. . CCDS94 MGSVNSRGHKAEAQVVMMGLDSAGKTTLLYKLKGHQLVETLPTVGFN 10 20 30 40 70 80 90 100 110 pF1KB6 SEELTIAG-MTFTTFDLGGHEQARRVWKNYLPAINGIVFLVDCADHSRLVESKVELNALM : : : ...: .:.::. : ::.:: . . .:...: .:..:: :: .::. .. CCDS94 VEPLKAPGHVSLTLWDVGGQAPLRASWKDYLEGTDILVYVLDSTDEARLPESAAELTEVL 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB6 TDETISNVPILILGNKIDRTDAISEEKLREIFGLYGQTTGKGNVTLKELNARPMEVFMCS .: ....::.:.:.:: . ::. :.:. ..:.... . :. :: CCDS94 NDPNMAGVPFLVLANKQEAPDALPLLKIRN------------RLSLERFQDHCWELRGCS 110 120 130 140 150 180 190 pF1KB6 VLKRQGYGEGFRWLSQYID .: .: :... : CCDS94 ALTGEGLPEALQSLWSLLKSRSCMCLQARAHGAERGDSKRS 160 170 180 190 >>CCDS8088.1 ARL2 gene_id:402|Hs108|chr11 (184 aa) initn: 301 init1: 278 opt: 298 Z-score: 358.6 bits: 73.1 E(32554): 1.2e-13 Smith-Waterman score: 298; 32.2% identity (71.3% similar) in 143 aa overlap (11-153:2-144) 10 20 30 40 50 60 pF1KB6 MSFIFEWIYNGFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPT :. ..:. . .. .:..::::::::::.:. .. . . ::: . CCDS80 MGLLTILKKMKQKERELRLLMLGLDNAGKTTILKKFNGEDIDTISPTLGFN 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 SEELTIAGMTFTTFDLGGHEQARRVWKNYLPAINGIVFLVDCADHSRLVESKVELNALMT . : :. .. .:.::... : :.::. . .:....:: ::..:. . . ::..:.. CCDS80 IKTLEHRGFKLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSADRQRMQDCQRELQSLLV 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 DETISNVPILILGNKIDRTDAISEEKLREIFGLYGQTTGKGNVTLKELNARPMEVFMCSV .: .... .::..:: : :.: . .::.. : CCDS80 EERLAGATLLIFANKQDLPGALSSNAIREVLELDSIRSHHWCIQGCSAVTGENLLPGIDW 120 130 140 150 160 170 190 pF1KB6 LKRQGYGEGFRWLSQYID CCDS80 LLDDISSRIFTAD 180 >>CCDS2928.1 ARL6 gene_id:84100|Hs108|chr3 (186 aa) initn: 320 init1: 163 opt: 297 Z-score: 357.3 bits: 72.9 E(32554): 1.4e-13 Smith-Waterman score: 325; 31.0% identity (67.9% similar) in 184 aa overlap (18-197:10-181) 10 20 30 40 50 pF1KB6 MSFIFEWIYNGFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLHMLK-DDRLGQHV-PTLH .::: :: ... :::::.::::... :: .. .:.. ::. CCDS29 MGLLDRLSVLLGLKKKEVHVLCLGLDNSGKTTIINKLKPSNAQSQNILPTIG 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 PTSEELTIAGMTFTTFDLGGHEQARRVWKNYLPAINGIVFLVDCADHSRLVESKVELNAL . :.. ....::.::..:. . : .:..: ..:.:..: .:. :.: .: ::..: CCDS29 FSIEKFKSSSLSFTVFDMSGQGRYRNLWEHYYKEGQAIIFVIDSSDRLRMVVAKEELDTL 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 MTDETISN--VPILILGNKIDRTDAISEEKLREIFGLYGQTTGKGNVTLKELNARPMEVF .. :.. .:::...::.: ::.. :. ... :.... .: .. CCDS29 LNHPDIKHRRIPILFFANKMDLRDAVTSVKVSQLL------------CLENIKDKPWHIC 120 130 140 150 160 180 190 pF1KB6 MCSVLKRQGYGEGFRWLSQYID ...: .: :: ::.. : CCDS29 ASDAIKGEGLQEGVDWLQDQIQTVKT 170 180 >>CCDS3986.1 TRIM23 gene_id:373|Hs108|chr5 (546 aa) initn: 290 init1: 290 opt: 302 Z-score: 357.2 bits: 74.4 E(32554): 1.4e-13 Smith-Waterman score: 302; 35.8% identity (71.6% similar) in 134 aa overlap (27-160:406-539) 10 20 30 40 50 pF1KB6 MSFIFEWIYNGFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPT ..: ::::.:::::.: ::.:.. : .:: CCDS39 EVADHIQLDASIPVTFTKDNRVHIGPKMEIRVVTLGLDGAGKTTILFKLKQDEFMQPIPT 380 390 400 410 420 430 60 70 80 90 100 110 pF1KB6 LHPTSEELTIAGMTFTTFDLGGHEQARRVWKNYLPAINGIVFLVDCADHSRLVESKVELN . . : . .. :: .:.::... : .::.: ...::.:: . ..:. :.. :: CCDS39 IGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVDSSHRDRISEAHSELA 440 450 460 470 480 490 120 130 140 150 160 170 pF1KB6 ALMTDETISNVPILILGNKIDRTDAISEEKLREIFGLYGQTTGKGNVTLKELNARPMEVF :.:.. . .. .::..:: : . :.: :.. :...:. :. CCDS39 KLLTEKELRDALLLIFANKQDVAGALSVEEITELLSLHKLCCGRSCFSDNM 500 510 520 530 540 180 190 pF1KB6 MCSVLKRQGYGEGFRWLSQYID >>CCDS3192.1 ARL14 gene_id:80117|Hs108|chr3 (192 aa) initn: 284 init1: 198 opt: 297 Z-score: 357.2 bits: 72.9 E(32554): 1.4e-13 Smith-Waterman score: 319; 32.0% identity (64.6% similar) in 175 aa overlap (24-197:12-175) 10 20 30 40 50 60 pF1KB6 MSFIFEWIYNGFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPTLHPT :......::::.:::.:::. :: . .::. . CCDS31 MGSLGSKNPQTKQAQVLLLGLDSAGKSTLLYKLKLAKDITTIPTIGFN 10 20 30 40 70 80 90 100 110 pF1KB6 SEELTIA-GMTFTTFDLGGHEQARRVWKNYLPAINGIVFLVDCADHSRLVESKVELNALM : . . ....:..:.::.:. : :: : .:.:..:: .:..:: ::. ... .. CCDS31 VEMIELERNLSLTVWDVGGQEKMRTVWGCYCENTDGLVYVVDSTDKQRLEESQRQFEHIL 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB6 TDETISNVPILILGNKIDRTDAISEEKLREIFGLYGQTTGKGNVTLKELNARPMEVFMCS .: :.:::...:.:: : :.. : . ..: . : . : : : CCDS31 KNEHIKNVPVVLLANKQDMPGALTAEDITRMFKVK-----------KLCSDRNWYVQPCC 110 120 130 140 150 180 190 pF1KB6 VLKRQGYGEGFRWLSQYID .: .: ..::: :. .. CCDS31 ALTGEGLAQGFRKLTGFVKSHMKSRGDTLAFFKQN 160 170 180 190 >>CCDS3987.1 TRIM23 gene_id:373|Hs108|chr5 (574 aa) initn: 316 init1: 290 opt: 302 Z-score: 356.9 bits: 74.4 E(32554): 1.5e-13 Smith-Waterman score: 318; 32.7% identity (64.9% similar) in 171 aa overlap (27-197:406-565) 10 20 30 40 50 pF1KB6 MSFIFEWIYNGFSSVLQFLGLYKKSGKLVFLGLDNAGKTTLLHMLKDDRLGQHVPT ..: ::::.:::::.: ::.:.. : .:: CCDS39 EVADHIQLDASIPVTFTKDNRVHIGPKMEIRVVTLGLDGAGKTTILFKLKQDEFMQPIPT 380 390 400 410 420 430 60 70 80 90 100 110 pF1KB6 LHPTSEELTIAGMTFTTFDLGGHEQARRVWKNYLPAINGIVFLVDCADHSRLVESKVELN . . : . .. :: .:.::... : .::.: ...::.:: . ..:. :.. :: CCDS39 IGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHYYLNTQAVVFVVDSSHRDRISEAHSELA 440 450 460 470 480 490 120 130 140 150 160 170 pF1KB6 ALMTDETISNVPILILGNKIDRTDAISEEKLREIFGLYGQTTGKGNVTLKELNARPMEVF :.:.. . .. .::..:: : . :.: :.. :...:. : : . CCDS39 KLLTEKELRDALLLIFANKQDVAGALSVEEITELLSLHKLCCG-----------RSWYIQ 500 510 520 530 540 180 190 pF1KB6 MCSVLKRQGYGEGFRWLSQYID :.. . .: ::. :::. . CCDS39 GCDARSGMGLYEGLDWLSRQLVAAGVLDVA 550 560 570 198 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:11:44 2016 done: Sat Nov 5 04:11:45 2016 Total Scan time: 1.590 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]