Result of FASTA (omim) for
pF1KB6874
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6874, 198 aa
1>>>pF1KB6874 198 - 198 aa - 198 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9587+/-0.000326; mu= 10.8737+/- 0.020
mean_var=85.5588+/-17.450, 0's: 0 Z-trim(117.4): 16 B-trim: 1072 in 2/52
Lambda= 0.138657
statistics sampled from 29285 (29301) to 29285 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.728), E-opt: 0.2 (0.344), width: 16
Scan time: 6.350
The best scores are: opt bits E(85289)
NP_002990 (OMIM: 600017) syndecan-4 precursor [Hom ( 198) 1275 264.2 9.8e-71
XP_011527279 (OMIM: 600017) PREDICTED: syndecan-4 ( 126) 807 170.5 1e-42
NP_002989 (OMIM: 142460) syndecan-2 precursor [Hom ( 201) 359 81.0 1.4e-15
XP_011515514 (OMIM: 142460) PREDICTED: syndecan-2 ( 172) 347 78.5 6.6e-15
XP_011540768 (OMIM: 186357,601665) PREDICTED: synd ( 400) 225 54.3 3e-07
XP_011540766 (OMIM: 186357,601665) PREDICTED: synd ( 430) 225 54.4 3.1e-07
XP_011540765 (OMIM: 186357,601665) PREDICTED: synd ( 431) 225 54.4 3.2e-07
NP_055469 (OMIM: 186357,601665) syndecan-3 precurs ( 442) 225 54.4 3.2e-07
XP_005262679 (OMIM: 186355) PREDICTED: syndecan-1 ( 292) 214 52.1 1.1e-06
XP_005262678 (OMIM: 186355) PREDICTED: syndecan-1 ( 305) 214 52.1 1.1e-06
NP_001006947 (OMIM: 186355) syndecan-1 precursor [ ( 310) 214 52.1 1.1e-06
NP_002988 (OMIM: 186355) syndecan-1 precursor [Hom ( 310) 214 52.1 1.1e-06
XP_005262677 (OMIM: 186355) PREDICTED: syndecan-1 ( 334) 214 52.1 1.2e-06
>>NP_002990 (OMIM: 600017) syndecan-4 precursor [Homo sa (198 aa)
initn: 1275 init1: 1275 opt: 1275 Z-score: 1390.9 bits: 264.2 E(85289): 9.8e-71
Smith-Waterman score: 1275; 99.5% identity (100.0% similar) in 198 aa overlap (1-198:1-198)
10 20 30 40 50 60
pF1KB6 MAPARLFALLLLFVGGVAESIRETEVIDPQDLLEGRYFSGALPDDEDVVGPGQESDDFEL
:::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAPARLFALLLFFVGGVAESIRETEVIDPQDLLEGRYFSGALPDDEDVVGPGQESDDFEL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 SGSGDLDDLEDSMIGPEVVHPLVPLDNHIPERAGSGSQVPTEPKKLEENEVIPKRISPVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SGSGDLDDLEDSMIGPEVVHPLVPLDNHIPERAGSGSQVPTEPKKLEENEVIPKRISPVE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 ESEDVSNKVSMSSTVQGSNIFERTEVLAALIVGGIVGILFAVFLILLLMYRMKKKDEGSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ESEDVSNKVSMSSTVQGSNIFERTEVLAALIVGGIVGILFAVFLILLLMYRMKKKDEGSY
130 140 150 160 170 180
190
pF1KB6 DLGKKPIYKKAPTNEFYA
::::::::::::::::::
NP_002 DLGKKPIYKKAPTNEFYA
190
>>XP_011527279 (OMIM: 600017) PREDICTED: syndecan-4 isof (126 aa)
initn: 807 init1: 807 opt: 807 Z-score: 887.9 bits: 170.5 E(85289): 1e-42
Smith-Waterman score: 807; 100.0% identity (100.0% similar) in 126 aa overlap (73-198:1-126)
50 60 70 80 90 100
pF1KB6 PDDEDVVGPGQESDDFELSGSGDLDDLEDSMIGPEVVHPLVPLDNHIPERAGSGSQVPTE
::::::::::::::::::::::::::::::
XP_011 MIGPEVVHPLVPLDNHIPERAGSGSQVPTE
10 20 30
110 120 130 140 150 160
pF1KB6 PKKLEENEVIPKRISPVEESEDVSNKVSMSSTVQGSNIFERTEVLAALIVGGIVGILFAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKKLEENEVIPKRISPVEESEDVSNKVSMSSTVQGSNIFERTEVLAALIVGGIVGILFAV
40 50 60 70 80 90
170 180 190
pF1KB6 FLILLLMYRMKKKDEGSYDLGKKPIYKKAPTNEFYA
::::::::::::::::::::::::::::::::::::
XP_011 FLILLLMYRMKKKDEGSYDLGKKPIYKKAPTNEFYA
100 110 120
>>NP_002989 (OMIM: 142460) syndecan-2 precursor [Homo sa (201 aa)
initn: 322 init1: 229 opt: 359 Z-score: 400.5 bits: 81.0 E(85289): 1.4e-15
Smith-Waterman score: 371; 39.1% identity (66.2% similar) in 207 aa overlap (8-198:4-201)
10 20 30 40 50
pF1KB6 MAPARLFALLLLFVGGVAESIRET--EVIDPQDL-LEGRYF---SGALP-DDEDVV---G
: .:: .: :: :. :. . .:. :.. . ::. : ::.: . :
NP_002 MRRAWILLTLGLVACVSAESRAELTSDKDMYLDNSSIEEASGVYPIDDDDYASASG
10 20 30 40 50
60 70 80 90 100
pF1KB6 PGQESD--DFELSGSGDLDDLEDSMIGPEVVHPLVPLDNHIPERAGSGSQVPTEPKKLEE
: . : . ::. : : . . .:.: . ..:.:: .. : .. : .: .
NP_002 SGADEDVESPELTTSRPLPKILLTSAAPKVETTTLNIQNKIPAQTKSPEETDKEKVHLSD
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB6 NEVIPKRISPVEESEDVSNKVSMSSTVQGSNIFERTEVLAALIVGGIVGILFAVFLILLL
.: ....:.::. .: . .....:.:::::::.:.::..:.:::.::::::
NP_002 SE---RKMDPAEEDTNVY------TEKHSDSLFKRTEVLAAVIAGGVIGFLFAIFLILLL
120 130 140 150 160
170 180 190
pF1KB6 MYRMKKKDEGSYDLG-KKP---IYKKAPTNEFYA
.:::.:::::::::: .:: :.::::.::::
NP_002 VYRMRKKDEGSYDLGERKPSSAAYQKAPTKEFYA
170 180 190 200
>>XP_011515514 (OMIM: 142460) PREDICTED: syndecan-2 isof (172 aa)
initn: 322 init1: 229 opt: 347 Z-score: 388.6 bits: 78.5 E(85289): 6.6e-15
Smith-Waterman score: 365; 41.8% identity (69.4% similar) in 170 aa overlap (39-198:12-172)
10 20 30 40 50 60
pF1KB6 LLLLFVGGVAESIRETEVIDPQDLLEGRYFSGALP-DDEDVV---GPGQESD--DFELSG
::. : ::.: . : : . : . ::.
XP_011 MYLDNSSIEEASGVYPIDDDDYASASGSGADEDVESPELTT
10 20 30 40
70 80 90 100 110 120
pF1KB6 SGDLDDLEDSMIGPEVVHPLVPLDNHIPERAGSGSQVPTEPKKLEENEVIPKRISPVEES
: : . . .:.: . ..:.:: .. : .. : .: ..: ....:.::.
XP_011 SRPLPKILLTSAAPKVETTTLNIQNKIPAQTKSPEETDKEKVHLSDSE---RKMDPAEED
50 60 70 80 90
130 140 150 160 170 180
pF1KB6 EDVSNKVSMSSTVQGSNIFERTEVLAALIVGGIVGILFAVFLILLLMYRMKKKDEGSYDL
.: .. .....:.:::::::.:.::..:.:::.::::::.:::.:::::::::
XP_011 TNVYTEK------HSDSLFKRTEVLAAVIAGGVIGFLFAIFLILLLVYRMRKKDEGSYDL
100 110 120 130 140 150
190
pF1KB6 G-KKP---IYKKAPTNEFYA
: .:: :.::::.::::
XP_011 GERKPSSAAYQKAPTKEFYA
160 170
>>XP_011540768 (OMIM: 186357,601665) PREDICTED: syndecan (400 aa)
initn: 248 init1: 201 opt: 225 Z-score: 251.2 bits: 54.3 E(85289): 3e-07
Smith-Waterman score: 241; 34.8% identity (60.4% similar) in 164 aa overlap (43-198:250-400)
20 30 40 50 60 70
pF1KB6 FVGGVAESIRETEVIDPQDLLEGRYFSGALPDDEDVVGPGQESDDFELSG--SGDLDDLE
: : . .. . .:: :::.. :
XP_011 PATTQEPDIPERSTLPLGTTAPGPTEVAQTPTPETFLTTIRDEPEVPVSGGPSGDFELPE
220 230 240 250 260 270
80 90 100 110 120 130
pF1KB6 DSMIGPEVVHPLVPLDNHIPERAGSGSQVPTEPKKLEENEVIPKRISPVEESEDVSNKVS
. :.... .: . .:..... . : : .. : .: .. ... :
XP_011 EETTQPDTANEVVAV-------GGAAAKASSPPGTLPKGA----RPGPGLLDNAIDSGSS
280 290 300 310 320
140 150 160 170 180
pF1KB6 MSSTVQGSNIFERTEVLAALIVGGIVGILFAVFLILLLMYRMKKKDEGSYDLGKKP----
.. : : :.:: :::.:.::::.:: :::.::. ::.::::::::::: : ..:
XP_011 AAQLPQKS-ILERKEVLVAVIVGGVVGALFAAFLVTLLIYRMKKKDEGSYTL-EEPKQAS
330 340 350 360 370 380
190
pF1KB6 -IYKKAPTNE-FYA
:.: .: :::
XP_011 VTYQKPDKQEEFYA
390 400
>>XP_011540766 (OMIM: 186357,601665) PREDICTED: syndecan (430 aa)
initn: 252 init1: 201 opt: 225 Z-score: 250.8 bits: 54.4 E(85289): 3.1e-07
Smith-Waterman score: 241; 34.8% identity (60.4% similar) in 164 aa overlap (43-198:280-430)
20 30 40 50 60 70
pF1KB6 FVGGVAESIRETEVIDPQDLLEGRYFSGALPDDEDVVGPGQESDDFELSG--SGDLDDLE
: : . .. . .:: :::.. :
XP_011 PATTQEPDIPERSTLPLGTTAPGPTEVAQTPTPETFLTTIRDEPEVPVSGGPSGDFELPE
250 260 270 280 290 300
80 90 100 110 120 130
pF1KB6 DSMIGPEVVHPLVPLDNHIPERAGSGSQVPTEPKKLEENEVIPKRISPVEESEDVSNKVS
. :.... .: . .:..... . : : .. : .: .. ... :
XP_011 EETTQPDTANEVVAV-------GGAAAKASSPPGTLPKGA----RPGPGLLDNAIDSGSS
310 320 330 340 350
140 150 160 170 180
pF1KB6 MSSTVQGSNIFERTEVLAALIVGGIVGILFAVFLILLLMYRMKKKDEGSYDLGKKP----
.. : : :.:: :::.:.::::.:: :::.::. ::.::::::::::: : ..:
XP_011 AAQLPQKS-ILERKEVLVAVIVGGVVGALFAAFLVTLLIYRMKKKDEGSYTL-EEPKQAS
360 370 380 390 400 410
190
pF1KB6 -IYKKAPTNE-FYA
:.: .: :::
XP_011 VTYQKPDKQEEFYA
420 430
>>XP_011540765 (OMIM: 186357,601665) PREDICTED: syndecan (431 aa)
initn: 252 init1: 201 opt: 225 Z-score: 250.7 bits: 54.4 E(85289): 3.2e-07
Smith-Waterman score: 241; 34.8% identity (60.4% similar) in 164 aa overlap (43-198:281-431)
20 30 40 50 60 70
pF1KB6 FVGGVAESIRETEVIDPQDLLEGRYFSGALPDDEDVVGPGQESDDFELSG--SGDLDDLE
: : . .. . .:: :::.. :
XP_011 PATTQEPDIPERSTLPLGTTAPGPTEVAQTPTPETFLTTIRDEPEVPVSGGPSGDFELPE
260 270 280 290 300 310
80 90 100 110 120 130
pF1KB6 DSMIGPEVVHPLVPLDNHIPERAGSGSQVPTEPKKLEENEVIPKRISPVEESEDVSNKVS
. :.... .: . .:..... . : : .. : .: .. ... :
XP_011 EETTQPDTANEVVAV-------GGAAAKASSPPGTLPKGA----RPGPGLLDNAIDSGSS
320 330 340 350
140 150 160 170 180
pF1KB6 MSSTVQGSNIFERTEVLAALIVGGIVGILFAVFLILLLMYRMKKKDEGSYDLGKKP----
.. : : :.:: :::.:.::::.:: :::.::. ::.::::::::::: : ..:
XP_011 AAQLPQKS-ILERKEVLVAVIVGGVVGALFAAFLVTLLIYRMKKKDEGSYTL-EEPKQAS
360 370 380 390 400 410
190
pF1KB6 -IYKKAPTNE-FYA
:.: .: :::
XP_011 VTYQKPDKQEEFYA
420 430
>>NP_055469 (OMIM: 186357,601665) syndecan-3 precursor [ (442 aa)
initn: 248 init1: 201 opt: 225 Z-score: 250.6 bits: 54.4 E(85289): 3.2e-07
Smith-Waterman score: 241; 34.8% identity (60.4% similar) in 164 aa overlap (43-198:292-442)
20 30 40 50 60 70
pF1KB6 FVGGVAESIRETEVIDPQDLLEGRYFSGALPDDEDVVGPGQESDDFELSG--SGDLDDLE
: : . .. . .:: :::.. :
NP_055 PATTQEPDIPERSTLPLGTTAPGPTEVAQTPTPETFLTTIRDEPEVPVSGGPSGDFELPE
270 280 290 300 310 320
80 90 100 110 120 130
pF1KB6 DSMIGPEVVHPLVPLDNHIPERAGSGSQVPTEPKKLEENEVIPKRISPVEESEDVSNKVS
. :.... .: . .:..... . : : .. : .: .. ... :
NP_055 EETTQPDTANEVVAV-------GGAAAKASSPPGTLPKGA----RPGPGLLDNAIDSGSS
330 340 350 360 370
140 150 160 170 180
pF1KB6 MSSTVQGSNIFERTEVLAALIVGGIVGILFAVFLILLLMYRMKKKDEGSYDLGKKP----
.. : : :.:: :::.:.::::.:: :::.::. ::.::::::::::: : ..:
NP_055 AAQLPQKS-ILERKEVLVAVIVGGVVGALFAAFLVTLLIYRMKKKDEGSYTL-EEPKQAS
380 390 400 410 420
190
pF1KB6 -IYKKAPTNE-FYA
:.: .: :::
NP_055 VTYQKPDKQEEFYA
430 440
>>XP_005262679 (OMIM: 186355) PREDICTED: syndecan-1 isof (292 aa)
initn: 233 init1: 165 opt: 214 Z-score: 241.4 bits: 52.1 E(85289): 1.1e-06
Smith-Waterman score: 214; 38.3% identity (69.2% similar) in 120 aa overlap (87-198:180-292)
60 70 80 90 100 110
pF1KB6 DFELSGSGDLDDLEDSMIGPEVVHPLVPLDNHIPERAGSGSQVPTEPKKLEENEVIPKRI
...: ::: : : . :.. :.
XP_005 AGPSQADLHTPHTEDGGPSATERAAEDGASSQLPAAEGSGEQDFTFETSGENTAVVA---
150 160 170 180 190 200
120 130 140 150 160 170
pF1KB6 SPVEESEDVSNKVSMSSTVQGSNIFERTEVLAALIVGGIVGILFAVFLILLLMYRMKKKD
:: .. .. :....: ......: :::...:.::.::..::: :. ...:::::::
XP_005 --VEPDRRNQSPVDQGATGASQGLLDRKEVLGGVIAGGLVGLIFAVCLVGFMLYRMKKKD
210 220 230 240 250 260
180 190
pF1KB6 EGSYDLGKKP------IYKKAPTN--EFYA
::::.: ..: :.: ::. ::::
XP_005 EGSYSL-EEPKQANGGAYQK-PTKQEEFYA
270 280 290
>>XP_005262678 (OMIM: 186355) PREDICTED: syndecan-1 isof (305 aa)
initn: 233 init1: 165 opt: 214 Z-score: 241.1 bits: 52.1 E(85289): 1.1e-06
Smith-Waterman score: 214; 38.3% identity (69.2% similar) in 120 aa overlap (87-198:193-305)
60 70 80 90 100 110
pF1KB6 DFELSGSGDLDDLEDSMIGPEVVHPLVPLDNHIPERAGSGSQVPTEPKKLEENEVIPKRI
...: ::: : : . :.. :.
XP_005 AGPSQADLHTPHTEDGGPSATERAAEDGASSQLPAAEGSGEQDFTFETSGENTAVVA---
170 180 190 200 210
120 130 140 150 160 170
pF1KB6 SPVEESEDVSNKVSMSSTVQGSNIFERTEVLAALIVGGIVGILFAVFLILLLMYRMKKKD
:: .. .. :....: ......: :::...:.::.::..::: :. ...:::::::
XP_005 --VEPDRRNQSPVDQGATGASQGLLDRKEVLGGVIAGGLVGLIFAVCLVGFMLYRMKKKD
220 230 240 250 260 270
180 190
pF1KB6 EGSYDLGKKP------IYKKAPTN--EFYA
::::.: ..: :.: ::. ::::
XP_005 EGSYSL-EEPKQANGGAYQK-PTKQEEFYA
280 290 300
198 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 00:07:49 2016 done: Sat Nov 5 00:07:50 2016
Total Scan time: 6.350 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]