FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6875, 159 aa 1>>>pF1KB6875 159 - 159 aa - 159 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0621+/-0.000691; mu= 12.4962+/- 0.042 mean_var=52.2744+/-10.472, 0's: 0 Z-trim(108.1): 19 B-trim: 0 in 0/48 Lambda= 0.177390 statistics sampled from 9959 (9977) to 9959 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.71), E-opt: 0.2 (0.306), width: 16 Scan time: 1.740 The best scores are: opt bits E(32554) CCDS2113.1 IL1RN gene_id:3557|Hs108|chr2 ( 159) 1079 283.5 3.6e-77 CCDS46396.1 IL1RN gene_id:3557|Hs108|chr2 ( 177) 1062 279.2 8.2e-76 CCDS2114.1 IL1RN gene_id:3557|Hs108|chr2 ( 180) 1062 279.2 8.3e-76 CCDS2115.1 IL1RN gene_id:3557|Hs108|chr2 ( 143) 974 256.7 4.1e-69 CCDS2111.1 IL36RN gene_id:26525|Hs108|chr2 ( 155) 414 113.3 6.1e-26 CCDS2112.1 IL1F10 gene_id:84639|Hs108|chr2 ( 152) 322 89.8 7.3e-19 CCDS42734.1 IL36A gene_id:27179|Hs108|chr2 ( 158) 236 67.8 3.2e-12 CCDS2110.1 IL36B gene_id:27177|Hs108|chr2 ( 157) 218 63.2 7.7e-11 >>CCDS2113.1 IL1RN gene_id:3557|Hs108|chr2 (159 aa) initn: 1079 init1: 1079 opt: 1079 Z-score: 1498.8 bits: 283.5 E(32554): 3.6e-77 Smith-Waterman score: 1079; 100.0% identity (100.0% similar) in 159 aa overlap (1-159:1-159) 10 20 30 40 50 60 pF1KB6 MALETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVPIEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 MALETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVPIEP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSGPTTSFES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 HALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSGPTTSFES 70 80 90 100 110 120 130 140 150 pF1KB6 AACPGWFLCTAMEADQPVSLTNMPDEGVMVTKFYFQEDE ::::::::::::::::::::::::::::::::::::::: CCDS21 AACPGWFLCTAMEADQPVSLTNMPDEGVMVTKFYFQEDE 130 140 150 >>CCDS46396.1 IL1RN gene_id:3557|Hs108|chr2 (177 aa) initn: 1062 init1: 1062 opt: 1062 Z-score: 1474.6 bits: 279.2 E(32554): 8.2e-76 Smith-Waterman score: 1062; 100.0% identity (100.0% similar) in 156 aa overlap (4-159:22-177) 10 20 30 40 pF1KB6 MALETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYL ::::::::::::::::::::::::::::::::::::::: CCDS46 MEICRGLRSHLITLLLFLFHSETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYL 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB6 QGPNVNLEEKIDVVPIEPHALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 QGPNVNLEEKIDVVPIEPHALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQD 70 80 90 100 110 120 110 120 130 140 150 pF1KB6 KRFAFIRSDSGPTTSFESAACPGWFLCTAMEADQPVSLTNMPDEGVMVTKFYFQEDE ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 KRFAFIRSDSGPTTSFESAACPGWFLCTAMEADQPVSLTNMPDEGVMVTKFYFQEDE 130 140 150 160 170 >>CCDS2114.1 IL1RN gene_id:3557|Hs108|chr2 (180 aa) initn: 1062 init1: 1062 opt: 1062 Z-score: 1474.4 bits: 279.2 E(32554): 8.3e-76 Smith-Waterman score: 1062; 100.0% identity (100.0% similar) in 156 aa overlap (4-159:25-180) 10 20 30 pF1KB6 MALETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVA :::::::::::::::::::::::::::::::::::: CCDS21 MALADLYEEGGGGGGEGEDNADSKETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVA 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB6 GYLQGPNVNLEEKIDVVPIEPHALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 GYLQGPNVNLEEKIDVVPIEPHALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENR 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB6 KQDKRFAFIRSDSGPTTSFESAACPGWFLCTAMEADQPVSLTNMPDEGVMVTKFYFQEDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 KQDKRFAFIRSDSGPTTSFESAACPGWFLCTAMEADQPVSLTNMPDEGVMVTKFYFQEDE 130 140 150 160 170 180 >>CCDS2115.1 IL1RN gene_id:3557|Hs108|chr2 (143 aa) initn: 974 init1: 974 opt: 974 Z-score: 1354.3 bits: 256.7 E(32554): 4.1e-69 Smith-Waterman score: 974; 100.0% identity (100.0% similar) in 143 aa overlap (17-159:1-143) 10 20 30 40 50 60 pF1KB6 MALETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVPIEP :::::::::::::::::::::::::::::::::::::::::::: CCDS21 MQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVPIEP 10 20 30 40 70 80 90 100 110 120 pF1KB6 HALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSGPTTSFES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS21 HALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSGPTTSFES 50 60 70 80 90 100 130 140 150 pF1KB6 AACPGWFLCTAMEADQPVSLTNMPDEGVMVTKFYFQEDE ::::::::::::::::::::::::::::::::::::::: CCDS21 AACPGWFLCTAMEADQPVSLTNMPDEGVMVTKFYFQEDE 110 120 130 140 >>CCDS2111.1 IL36RN gene_id:26525|Hs108|chr2 (155 aa) initn: 410 init1: 242 opt: 414 Z-score: 579.2 bits: 113.3 E(32554): 6.1e-26 Smith-Waterman score: 414; 49.3% identity (70.9% similar) in 148 aa overlap (20-157:9-153) 10 20 30 40 50 pF1KB6 MALETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVP--- ::. : :..::.::::.:: :.. .: :.:.::: CCDS21 MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRW 10 20 30 40 60 70 80 90 100 110 pF1KB6 ----IEPHALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSG . : ..::..::..:::: :.: : :: ::: .: . :..: :.: : : : CCDS21 LDASLSP--VILGVQGGSQCLSC-GVGQEPTLTLEPVNIMELYLGAKESKSFTFYRRDMG 50 60 70 80 90 100 120 130 140 150 pF1KB6 PTTSFESAACPGWFLCTAMEADQPVSLTNMPDEG---VMVTKFYFQEDE :.:::::: :::::::. :::::: ::..:..: . .: ::::. CCDS21 LTSSFESAAYPGWFLCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD 110 120 130 140 150 >>CCDS2112.1 IL1F10 gene_id:84639|Hs108|chr2 (152 aa) initn: 322 init1: 260 opt: 322 Z-score: 452.1 bits: 89.8 E(32554): 7.3e-19 Smith-Waterman score: 322; 42.3% identity (68.6% similar) in 137 aa overlap (26-157:16-150) 10 20 30 40 50 60 pF1KB6 MALETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVPIEP .::..: :..::..: . : ::: ..: . CCDS21 MCSLPMARYYIIKYADQKALYTRDGQLLVGDPVADNCC-AEKICILPNRG 10 20 30 40 70 80 90 100 110 pF1KB6 HA-----LFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSGPT : .::::.::. ::.::.. . :::: ::: .: .. .. ::.:..:.:: . CCDS21 LARTKVPIFLGIQGGSRCLACVETEEGPSLQLEDVNIEELYKGGEEATRFTFFQSSSGSA 50 60 70 80 90 100 120 130 140 150 pF1KB6 TSFESAACPGWFLCTAMEADQPVSLTNMPDEGVMVTKFYFQEDE .:.:: :::::: : .:::.::. .: :::::.. CCDS21 FRLEAAAWPGWFLCGPAEPQQPVQLTK-ESEPSARTKFYFEQSW 110 120 130 140 150 >>CCDS42734.1 IL36A gene_id:27179|Hs108|chr2 (158 aa) initn: 222 init1: 222 opt: 236 Z-score: 332.9 bits: 67.8 E(32554): 3.2e-12 Smith-Waterman score: 236; 32.8% identity (62.6% similar) in 131 aa overlap (18-141:11-141) 10 20 30 40 50 pF1KB6 MALETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVA----GYLQGPNVNLEEKIDVV : : :.:.... :... :.: .. .. : : CCDS42 MEKALKIDTPQQGSIQDINHRVWVLQDQTLIAVPRKDRMSPVTIALISCRHVE 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 PIEP---HALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSG .: . ..::..: ..:: :.: ::. :::. .: :: .. . : : : .:.:: CCDS42 TLEKDRGNPIYLGLNGLNLCLMCAKVGDQPTLQLKEKDIMDLYNQPEPVKSFLFYHSQSG 60 70 80 90 100 110 120 130 140 150 pF1KB6 PTTSFESAACPGWFLCTAMEADQPVSLTNMPDEGVMVTKFYFQEDE ...:::.: ::::. .. :. :. :: CCDS42 RNSTFESVAFPGWFIAVSSEGGCPLILTQELGKANTTDFGLTMLF 120 130 140 150 >>CCDS2110.1 IL36B gene_id:27177|Hs108|chr2 (157 aa) initn: 209 init1: 209 opt: 218 Z-score: 308.1 bits: 63.2 E(32554): 7.7e-11 Smith-Waterman score: 218; 31.3% identity (61.3% similar) in 150 aa overlap (18-159:10-157) 10 20 30 40 50 pF1KB6 MALETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYLQ---GP-NVNLEEKIDVV ... : : : .. : .:.:.:. :. : ...: :. CCDS21 MNPQREAAPKSYAIRDSRQMVWVLSGNSLIAAPLSRSIKPVTLHLIACRDTE 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 PIEP---HALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSG . . ..:::.: .:: :.. . :::. :: :: ..: .: : :... : CCDS21 FSDKEKGNMVYLGIKGKDLCLFCAEIQGKPTLQLKEKNIMDLYVEKKAQKPFLFFHNKEG 60 70 80 90 100 110 120 130 140 150 pF1KB6 PTTSFESAACPGWFLCTAMEADQPVSLTNMPDEGVMV-TKFYFQEDE :. :.:.. ::::. :. . ::. ::. ..:. :.::.. : CCDS21 STSVFQSVSYPGWFIATSTTSGQPIFLTK--ERGITNNTNFYLDSVE 120 130 140 150 159 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 07:35:28 2016 done: Sat Nov 5 07:35:28 2016 Total Scan time: 1.740 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]