FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6880, 201 aa 1>>>pF1KB6880 201 - 201 aa - 201 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3777+/-0.000282; mu= 13.7420+/- 0.018 mean_var=76.4595+/-15.113, 0's: 0 Z-trim(119.4): 14 B-trim: 71 in 1/56 Lambda= 0.146676 statistics sampled from 33430 (33444) to 33430 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.759), E-opt: 0.2 (0.392), width: 16 Scan time: 6.000 The best scores are: opt bits E(85289) NP_001308349 (OMIM: 602843) rho GDP-dissociation i ( 201) 1348 293.8 1.3e-79 NP_001308351 (OMIM: 602843) rho GDP-dissociation i ( 201) 1348 293.8 1.3e-79 NP_001308350 (OMIM: 602843) rho GDP-dissociation i ( 201) 1348 293.8 1.3e-79 NP_001166 (OMIM: 602843) rho GDP-dissociation inhi ( 201) 1348 293.8 1.3e-79 NP_001308352 (OMIM: 602843) rho GDP-dissociation i ( 201) 1348 293.8 1.3e-79 NP_001172006 (OMIM: 601925,615244) rho GDP-dissoci ( 204) 938 207.0 1.7e-53 NP_004300 (OMIM: 601925,615244) rho GDP-dissociati ( 204) 938 207.0 1.7e-53 NP_001167 (OMIM: 602844) rho GDP-dissociation inhi ( 225) 763 170.0 2.5e-42 NP_001288169 (OMIM: 601925,615244) rho GDP-dissoci ( 235) 738 164.8 1e-40 NP_001288170 (OMIM: 601925,615244) rho GDP-dissoci ( 235) 738 164.8 1e-40 NP_001288172 (OMIM: 601925,615244) rho GDP-dissoci ( 249) 623 140.4 2.3e-33 XP_011521876 (OMIM: 601925,615244) PREDICTED: rho ( 249) 623 140.4 2.3e-33 NP_001288171 (OMIM: 601925,615244) rho GDP-dissoci ( 337) 588 133.1 4.9e-31 NP_001172007 (OMIM: 601925,615244) rho GDP-dissoci ( 160) 567 128.5 5.9e-30 >>NP_001308349 (OMIM: 602843) rho GDP-dissociation inhib (201 aa) initn: 1348 init1: 1348 opt: 1348 Z-score: 1550.6 bits: 293.8 E(85289): 1.3e-79 Smith-Waterman score: 1348; 100.0% identity (100.0% similar) in 201 aa overlap (1-201:1-201) 10 20 30 40 50 60 pF1KB6 MTEKAPEPHVEEDDDDELDSKLNYKPPPQKSLKELQEMDKDDESLIKYKKTLLGDGPVVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTEKAPEPHVEEDDDDELDSKLNYKPPPQKSLKELQEMDKDDESLIKYKKTLLGDGPVVT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 DPKAPNVVVTRLTLVCESAPGPITMDLTGDLEALKKETIVLKEGSEYRVKIHFKVNRDIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DPKAPNVVVTRLTLVCESAPGPITMDLTGDLEALKKETIVLKEGSEYRVKIHFKVNRDIV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 SGLKYVQHTYRTGVKVDKATFMVGSYGPRPEEYEFLTPVEEAPKGMLARGTYHNKSFFTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGLKYVQHTYRTGVKVDKATFMVGSYGPRPEEYEFLTPVEEAPKGMLARGTYHNKSFFTD 130 140 150 160 170 180 190 200 pF1KB6 DDKQDHLSWEWNLSIKKEWTE ::::::::::::::::::::: NP_001 DDKQDHLSWEWNLSIKKEWTE 190 200 >>NP_001308351 (OMIM: 602843) rho GDP-dissociation inhib (201 aa) initn: 1348 init1: 1348 opt: 1348 Z-score: 1550.6 bits: 293.8 E(85289): 1.3e-79 Smith-Waterman score: 1348; 100.0% identity (100.0% similar) in 201 aa overlap (1-201:1-201) 10 20 30 40 50 60 pF1KB6 MTEKAPEPHVEEDDDDELDSKLNYKPPPQKSLKELQEMDKDDESLIKYKKTLLGDGPVVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTEKAPEPHVEEDDDDELDSKLNYKPPPQKSLKELQEMDKDDESLIKYKKTLLGDGPVVT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 DPKAPNVVVTRLTLVCESAPGPITMDLTGDLEALKKETIVLKEGSEYRVKIHFKVNRDIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DPKAPNVVVTRLTLVCESAPGPITMDLTGDLEALKKETIVLKEGSEYRVKIHFKVNRDIV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 SGLKYVQHTYRTGVKVDKATFMVGSYGPRPEEYEFLTPVEEAPKGMLARGTYHNKSFFTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGLKYVQHTYRTGVKVDKATFMVGSYGPRPEEYEFLTPVEEAPKGMLARGTYHNKSFFTD 130 140 150 160 170 180 190 200 pF1KB6 DDKQDHLSWEWNLSIKKEWTE ::::::::::::::::::::: NP_001 DDKQDHLSWEWNLSIKKEWTE 190 200 >>NP_001308350 (OMIM: 602843) rho GDP-dissociation inhib (201 aa) initn: 1348 init1: 1348 opt: 1348 Z-score: 1550.6 bits: 293.8 E(85289): 1.3e-79 Smith-Waterman score: 1348; 100.0% identity (100.0% similar) in 201 aa overlap (1-201:1-201) 10 20 30 40 50 60 pF1KB6 MTEKAPEPHVEEDDDDELDSKLNYKPPPQKSLKELQEMDKDDESLIKYKKTLLGDGPVVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTEKAPEPHVEEDDDDELDSKLNYKPPPQKSLKELQEMDKDDESLIKYKKTLLGDGPVVT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 DPKAPNVVVTRLTLVCESAPGPITMDLTGDLEALKKETIVLKEGSEYRVKIHFKVNRDIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DPKAPNVVVTRLTLVCESAPGPITMDLTGDLEALKKETIVLKEGSEYRVKIHFKVNRDIV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 SGLKYVQHTYRTGVKVDKATFMVGSYGPRPEEYEFLTPVEEAPKGMLARGTYHNKSFFTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGLKYVQHTYRTGVKVDKATFMVGSYGPRPEEYEFLTPVEEAPKGMLARGTYHNKSFFTD 130 140 150 160 170 180 190 200 pF1KB6 DDKQDHLSWEWNLSIKKEWTE ::::::::::::::::::::: NP_001 DDKQDHLSWEWNLSIKKEWTE 190 200 >>NP_001166 (OMIM: 602843) rho GDP-dissociation inhibito (201 aa) initn: 1348 init1: 1348 opt: 1348 Z-score: 1550.6 bits: 293.8 E(85289): 1.3e-79 Smith-Waterman score: 1348; 100.0% identity (100.0% similar) in 201 aa overlap (1-201:1-201) 10 20 30 40 50 60 pF1KB6 MTEKAPEPHVEEDDDDELDSKLNYKPPPQKSLKELQEMDKDDESLIKYKKTLLGDGPVVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTEKAPEPHVEEDDDDELDSKLNYKPPPQKSLKELQEMDKDDESLIKYKKTLLGDGPVVT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 DPKAPNVVVTRLTLVCESAPGPITMDLTGDLEALKKETIVLKEGSEYRVKIHFKVNRDIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DPKAPNVVVTRLTLVCESAPGPITMDLTGDLEALKKETIVLKEGSEYRVKIHFKVNRDIV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 SGLKYVQHTYRTGVKVDKATFMVGSYGPRPEEYEFLTPVEEAPKGMLARGTYHNKSFFTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGLKYVQHTYRTGVKVDKATFMVGSYGPRPEEYEFLTPVEEAPKGMLARGTYHNKSFFTD 130 140 150 160 170 180 190 200 pF1KB6 DDKQDHLSWEWNLSIKKEWTE ::::::::::::::::::::: NP_001 DDKQDHLSWEWNLSIKKEWTE 190 200 >>NP_001308352 (OMIM: 602843) rho GDP-dissociation inhib (201 aa) initn: 1348 init1: 1348 opt: 1348 Z-score: 1550.6 bits: 293.8 E(85289): 1.3e-79 Smith-Waterman score: 1348; 100.0% identity (100.0% similar) in 201 aa overlap (1-201:1-201) 10 20 30 40 50 60 pF1KB6 MTEKAPEPHVEEDDDDELDSKLNYKPPPQKSLKELQEMDKDDESLIKYKKTLLGDGPVVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MTEKAPEPHVEEDDDDELDSKLNYKPPPQKSLKELQEMDKDDESLIKYKKTLLGDGPVVT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 DPKAPNVVVTRLTLVCESAPGPITMDLTGDLEALKKETIVLKEGSEYRVKIHFKVNRDIV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DPKAPNVVVTRLTLVCESAPGPITMDLTGDLEALKKETIVLKEGSEYRVKIHFKVNRDIV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 SGLKYVQHTYRTGVKVDKATFMVGSYGPRPEEYEFLTPVEEAPKGMLARGTYHNKSFFTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SGLKYVQHTYRTGVKVDKATFMVGSYGPRPEEYEFLTPVEEAPKGMLARGTYHNKSFFTD 130 140 150 160 170 180 190 200 pF1KB6 DDKQDHLSWEWNLSIKKEWTE ::::::::::::::::::::: NP_001 DDKQDHLSWEWNLSIKKEWTE 190 200 >>NP_001172006 (OMIM: 601925,615244) rho GDP-dissociatio (204 aa) initn: 958 init1: 925 opt: 938 Z-score: 1081.6 bits: 207.0 E(85289): 1.7e-53 Smith-Waterman score: 938; 67.0% identity (85.0% similar) in 206 aa overlap (1-201:1-204) 10 20 30 40 50 pF1KB6 MTEKAPEPH-----VEEDDDDELDSKLNYKPPPQKSLKELQEMDKDDESLIKYKKTLLGD :.:. : . . :...:: ..::::: :::..:.::.::::::: :::..::: NP_001 MAEQEPTAEQLAQIAAENEEDE--HSVNYKPPAQKSIQEIQELDKDDESLRKYKEALLGR 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 GPVVTDPKAPNVVVTRLTLVCESAPGPITMDLTGDLEALKKETIVLKEGSEYRVKIHFKV : .::..:::::: ::::: :::::. .:::::::..::...::::: :::.:: :.: NP_001 VAVSADPNVPNVVVTGLTLVCSSAPGPLELDLTGDLESFKKQSFVLKEGVEYRIKISFRV 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 NRDIVSGLKYVQHTYRTGVKVDKATFMVGSYGPRPEEYEFLTPVEEAPKGMLARGTYHNK ::.::::.::.::::: :::.::. .:::::::: ::::::::::::::::::::.: : NP_001 NREIVSGMKYIQHTYRKGVKIDKTDYMVGSYGPRAEEYEFLTPVEEAPKGMLARGSYSIK 120 130 140 150 160 170 180 190 200 pF1KB6 SFFTDDDKQDHLSWEWNLSIKKEWTE : :::::: :::::::::.:::.: . NP_001 SRFTDDDKTDHLSWEWNLTIKKDWKD 180 190 200 >>NP_004300 (OMIM: 601925,615244) rho GDP-dissociation i (204 aa) initn: 958 init1: 925 opt: 938 Z-score: 1081.6 bits: 207.0 E(85289): 1.7e-53 Smith-Waterman score: 938; 67.0% identity (85.0% similar) in 206 aa overlap (1-201:1-204) 10 20 30 40 50 pF1KB6 MTEKAPEPH-----VEEDDDDELDSKLNYKPPPQKSLKELQEMDKDDESLIKYKKTLLGD :.:. : . . :...:: ..::::: :::..:.::.::::::: :::..::: NP_004 MAEQEPTAEQLAQIAAENEEDE--HSVNYKPPAQKSIQEIQELDKDDESLRKYKEALLGR 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 GPVVTDPKAPNVVVTRLTLVCESAPGPITMDLTGDLEALKKETIVLKEGSEYRVKIHFKV : .::..:::::: ::::: :::::. .:::::::..::...::::: :::.:: :.: NP_004 VAVSADPNVPNVVVTGLTLVCSSAPGPLELDLTGDLESFKKQSFVLKEGVEYRIKISFRV 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 NRDIVSGLKYVQHTYRTGVKVDKATFMVGSYGPRPEEYEFLTPVEEAPKGMLARGTYHNK ::.::::.::.::::: :::.::. .:::::::: ::::::::::::::::::::.: : NP_004 NREIVSGMKYIQHTYRKGVKIDKTDYMVGSYGPRAEEYEFLTPVEEAPKGMLARGSYSIK 120 130 140 150 160 170 180 190 200 pF1KB6 SFFTDDDKQDHLSWEWNLSIKKEWTE : :::::: :::::::::.:::.: . NP_004 SRFTDDDKTDHLSWEWNLTIKKDWKD 180 190 200 >>NP_001167 (OMIM: 602844) rho GDP-dissociation inhibito (225 aa) initn: 757 init1: 736 opt: 763 Z-score: 880.9 bits: 170.0 E(85289): 2.5e-42 Smith-Waterman score: 763; 57.8% identity (80.4% similar) in 199 aa overlap (3-201:31-225) 10 20 30 pF1KB6 MTEKAPEPHVEEDDDDELDSKLNYKPPPQKSL : .: : :.: :. . .:. : .::: NP_001 MLGLDACELGAQLLELLRLALCARVLLADKEGGP-PAVDEVLDEAVP---EYRAPGRKSL 10 20 30 40 50 40 50 60 70 80 90 pF1KB6 KELQEMDKDDESLIKYKKTLLGDGPVVTDPKAPNVVVTRLTLVCESAPGPITMDLTGDLE :....: ::.:: :::..::: : ..::. ::: ::::::. :.::::..::::::: NP_001 LEIRQLDPDDRSLAKYKRVLLGPLPPAVDPSLPNVQVTRLTLLSEQAPGPVVMDLTGDLA 60 70 80 90 100 110 100 110 120 130 140 150 pF1KB6 ALKKETIVLKEGSEYRVKIHFKVNRDIVSGLKYVQHTYRTGVKVDKATFMVGSYGPRPEE .:: ...::::: .::::: :::.:.:::::: ..:::: :..:::...::::::: .: NP_001 VLKDQVFVLKEGVDYRVKISFKVHREIVSGLKCLHHTYRRGLRVDKTVYMVGSYGPSAQE 120 130 140 150 160 170 160 170 180 190 200 pF1KB6 YEFLTPVEEAPKGMLARGTYHNKSFFTDDDKQDHLSWEWNLSIKKEWTE :::.:::::::.: :.:: : :.:::::. ::::::.: : ..: . NP_001 YEFVTPVEEAPRGALVRGPYLVVSLFTDDDRTHHLSWEWGLCICQDWKD 180 190 200 210 220 >>NP_001288169 (OMIM: 601925,615244) rho GDP-dissociatio (235 aa) initn: 758 init1: 725 opt: 738 Z-score: 852.0 bits: 164.8 E(85289): 1e-40 Smith-Waterman score: 738; 64.2% identity (84.4% similar) in 173 aa overlap (1-168:1-171) 10 20 30 40 50 pF1KB6 MTEKAPEPH-----VEEDDDDELDSKLNYKPPPQKSLKELQEMDKDDESLIKYKKTLLGD :.:. : . . :...:: ..::::: :::..:.::.::::::: :::..::: NP_001 MAEQEPTAEQLAQIAAENEEDE--HSVNYKPPAQKSIQEIQELDKDDESLRKYKEALLGR 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 GPVVTDPKAPNVVVTRLTLVCESAPGPITMDLTGDLEALKKETIVLKEGSEYRVKIHFKV : .::..:::::: ::::: :::::. .:::::::..::...::::: :::.:: :.: NP_001 VAVSADPNVPNVVVTGLTLVCSSAPGPLELDLTGDLESFKKQSFVLKEGVEYRIKISFRV 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 NRDIVSGLKYVQHTYRTGVKVDKATFMVGSYGPRPEEYEFLTPVEEAPKGMLARGTYHNK ::.::::.::.::::: :::.::. .:::::::: ::::::::::::::: .. NP_001 NREIVSGMKYIQHTYRKGVKIDKTDYMVGSYGPRAEEYEFLTPVEEAPKGSISPSHPRPG 120 130 140 150 160 170 180 190 200 pF1KB6 SFFTDDDKQDHLSWEWNLSIKKEWTE NP_001 FRRERSSHSPGPVVAPGRVRLLLRGGAGVWDARPRGGRAVLQPRCSLASPLVAVGPV 180 190 200 210 220 230 >>NP_001288170 (OMIM: 601925,615244) rho GDP-dissociatio (235 aa) initn: 758 init1: 725 opt: 738 Z-score: 852.0 bits: 164.8 E(85289): 1e-40 Smith-Waterman score: 738; 64.2% identity (84.4% similar) in 173 aa overlap (1-168:1-171) 10 20 30 40 50 pF1KB6 MTEKAPEPH-----VEEDDDDELDSKLNYKPPPQKSLKELQEMDKDDESLIKYKKTLLGD :.:. : . . :...:: ..::::: :::..:.::.::::::: :::..::: NP_001 MAEQEPTAEQLAQIAAENEEDE--HSVNYKPPAQKSIQEIQELDKDDESLRKYKEALLGR 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 GPVVTDPKAPNVVVTRLTLVCESAPGPITMDLTGDLEALKKETIVLKEGSEYRVKIHFKV : .::..:::::: ::::: :::::. .:::::::..::...::::: :::.:: :.: NP_001 VAVSADPNVPNVVVTGLTLVCSSAPGPLELDLTGDLESFKKQSFVLKEGVEYRIKISFRV 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 NRDIVSGLKYVQHTYRTGVKVDKATFMVGSYGPRPEEYEFLTPVEEAPKGMLARGTYHNK ::.::::.::.::::: :::.::. .:::::::: ::::::::::::::: .. NP_001 NREIVSGMKYIQHTYRKGVKIDKTDYMVGSYGPRAEEYEFLTPVEEAPKGSISPSHPRPG 120 130 140 150 160 170 180 190 200 pF1KB6 SFFTDDDKQDHLSWEWNLSIKKEWTE NP_001 FRRERSSHSPGPVVAPGRVRLLLRGGAGVWDARPRGGRAVLQPRCSLASPLVAVGPV 180 190 200 210 220 230 201 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 00:24:40 2016 done: Sat Nov 5 00:24:41 2016 Total Scan time: 6.000 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]