FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6881, 181 aa 1>>>pF1KB6881 181 - 181 aa - 181 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0351+/-0.000456; mu= 15.0266+/- 0.029 mean_var=100.6826+/-22.434, 0's: 0 Z-trim(111.2): 249 B-trim: 619 in 1/52 Lambda= 0.127819 statistics sampled from 19380 (19754) to 19380 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.606), E-opt: 0.2 (0.232), width: 16 Scan time: 5.420 The best scores are: opt bits E(85289) NP_001650 (OMIM: 103190) ADP-ribosylation factor 3 ( 181) 1186 229.0 3.1e-60 XP_005268913 (OMIM: 103190) PREDICTED: ADP-ribosyl ( 181) 1186 229.0 3.1e-60 NP_001649 (OMIM: 103180) ADP-ribosylation factor 1 ( 181) 1153 223.0 2.1e-58 NP_001019399 (OMIM: 103180) ADP-ribosylation facto ( 181) 1153 223.0 2.1e-58 NP_001019397 (OMIM: 103180) ADP-ribosylation facto ( 181) 1153 223.0 2.1e-58 NP_001019398 (OMIM: 103180) ADP-ribosylation facto ( 181) 1153 223.0 2.1e-58 NP_001651 (OMIM: 601177) ADP-ribosylation factor 4 ( 180) 960 187.4 1.1e-47 NP_001653 (OMIM: 103188) ADP-ribosylation factor 5 ( 180) 957 186.8 1.6e-47 NP_001654 (OMIM: 600464) ADP-ribosylation factor 6 ( 175) 860 168.9 3.8e-42 XP_006719454 (OMIM: 103190) PREDICTED: ADP-ribosyl ( 137) 822 161.8 4.2e-40 XP_016856722 (OMIM: 103180) PREDICTED: ADP-ribosyl ( 212) 800 157.9 9.3e-39 NP_001168 (OMIM: 603425) ADP-ribosylation factor-l ( 181) 719 142.9 2.6e-34 XP_005248554 (OMIM: 601747) PREDICTED: E3 ubiquiti ( 398) 697 139.3 7.3e-33 NP_001647 (OMIM: 601747) E3 ubiquitin-protein liga ( 574) 697 139.5 9.2e-33 NP_150230 (OMIM: 601747) E3 ubiquitin-protein liga ( 569) 613 124.0 4.2e-28 XP_016864933 (OMIM: 601747) PREDICTED: E3 ubiquiti ( 569) 613 124.0 4.2e-28 NP_036229 (OMIM: 608960) ADP-ribosylation factor-l ( 179) 598 120.6 1.4e-27 NP_848930 (OMIM: 608909) ADP-ribosylation factor-l ( 179) 598 120.6 1.4e-27 NP_150231 (OMIM: 601747) E3 ubiquitin-protein liga ( 546) 584 118.6 1.7e-26 NP_001658 (OMIM: 601175) ADP-ribosylation factor-l ( 184) 561 113.8 1.6e-25 NP_079323 (OMIM: 614439) ADP-ribosylation factor-l ( 192) 545 110.9 1.2e-24 XP_016871749 (OMIM: 604695) PREDICTED: ADP-ribosyl ( 182) 541 110.1 2e-24 NP_004302 (OMIM: 604695) ADP-ribosylation factor-l ( 182) 541 110.1 2e-24 NP_005728 (OMIM: 604787) ADP-ribosylation factor-l ( 192) 525 107.2 1.6e-23 NP_001269360 (OMIM: 604787) ADP-ribosylation facto ( 201) 525 107.2 1.7e-23 NP_001287997 (OMIM: 603425) ADP-ribosylation facto ( 135) 507 103.7 1.3e-22 NP_997625 (OMIM: 604786) ADP-ribosylation factor-l ( 200) 505 103.5 2.1e-22 NP_001182325 (OMIM: 604786) ADP-ribosylation facto ( 200) 505 103.5 2.1e-22 NP_005729 (OMIM: 604786) ADP-ribosylation factor-l ( 200) 505 103.5 2.1e-22 NP_001032241 (OMIM: 604786) ADP-ribosylation facto ( 200) 505 103.5 2.1e-22 NP_817114 (OMIM: 608960) ADP-ribosylation factor-l ( 142) 490 100.6 1.2e-21 NP_001032251 (OMIM: 608960) ADP-ribosylation facto ( 142) 490 100.6 1.2e-21 XP_005252458 (OMIM: 608909) PREDICTED: ADP-ribosyl ( 142) 486 99.8 1.9e-21 NP_001652 (OMIM: 600732) ADP-ribosylation factor-l ( 201) 474 97.8 1.1e-20 XP_011523084 (OMIM: 600732) PREDICTED: ADP-ribosyl ( 201) 474 97.8 1.1e-20 NP_001265222 (OMIM: 209900,268000,600151,608845,61 ( 186) 472 97.4 1.4e-20 NP_115522 (OMIM: 209900,268000,600151,608845,61357 ( 186) 472 97.4 1.4e-20 XP_016862800 (OMIM: 209900,268000,600151,608845,61 ( 186) 472 97.4 1.4e-20 NP_816931 (OMIM: 209900,268000,600151,608845,61357 ( 186) 472 97.4 1.4e-20 NP_001310442 (OMIM: 209900,268000,600151,608845,61 ( 193) 458 94.8 8.4e-20 XP_005266310 (OMIM: 609351) PREDICTED: ADP-ribosyl ( 196) 448 93.0 3.1e-19 NP_612459 (OMIM: 609351) ADP-ribosylation factor-l ( 196) 448 93.0 3.1e-19 NP_060654 (OMIM: 616596) ADP-ribosylation factor-l ( 186) 399 83.9 1.6e-16 XP_016862801 (OMIM: 209900,268000,600151,608845,61 ( 159) 388 81.8 5.7e-16 NP_001310443 (OMIM: 209900,268000,600151,608845,61 ( 159) 388 81.8 5.7e-16 NP_620150 (OMIM: 616597) ADP-ribosylation factor-l ( 186) 386 81.5 8.2e-16 NP_001186674 (OMIM: 601175) ADP-ribosylation facto ( 157) 370 78.5 5.7e-15 NP_001254476 (OMIM: 604699) ADP-ribosylation facto ( 201) 354 75.7 5.1e-14 NP_001254477 (OMIM: 604699) ADP-ribosylation facto ( 201) 354 75.7 5.1e-14 XP_016883065 (OMIM: 604699) PREDICTED: ADP-ribosyl ( 201) 354 75.7 5.1e-14 >>NP_001650 (OMIM: 103190) ADP-ribosylation factor 3 [Ho (181 aa) initn: 1186 init1: 1186 opt: 1186 Z-score: 1202.3 bits: 229.0 E(85289): 3.1e-60 Smith-Waterman score: 1186; 100.0% identity (100.0% similar) in 181 aa overlap (1-181:1-181) 10 20 30 40 50 60 pF1KB6 MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNK 130 140 150 160 170 180 pF1KB6 K : NP_001 K >>XP_005268913 (OMIM: 103190) PREDICTED: ADP-ribosylatio (181 aa) initn: 1186 init1: 1186 opt: 1186 Z-score: 1202.3 bits: 229.0 E(85289): 3.1e-60 Smith-Waterman score: 1186; 100.0% identity (100.0% similar) in 181 aa overlap (1-181:1-181) 10 20 30 40 50 60 pF1KB6 MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNK 130 140 150 160 170 180 pF1KB6 K : XP_005 K >>NP_001649 (OMIM: 103180) ADP-ribosylation factor 1 [Ho (181 aa) initn: 1153 init1: 1153 opt: 1153 Z-score: 1169.4 bits: 223.0 E(85289): 2.1e-58 Smith-Waterman score: 1153; 96.1% identity (100.0% similar) in 181 aa overlap (1-181:1-181) 10 20 30 40 50 60 pF1KB6 MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :::::.::.:.:.::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNK :::::::::::::::::::::::::::::::::::::::::::::::::::::.:::.:. NP_001 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ 130 140 150 160 170 180 pF1KB6 K : NP_001 K >>NP_001019399 (OMIM: 103180) ADP-ribosylation factor 1 (181 aa) initn: 1153 init1: 1153 opt: 1153 Z-score: 1169.4 bits: 223.0 E(85289): 2.1e-58 Smith-Waterman score: 1153; 96.1% identity (100.0% similar) in 181 aa overlap (1-181:1-181) 10 20 30 40 50 60 pF1KB6 MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :::::.::.:.:.::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNK :::::::::::::::::::::::::::::::::::::::::::::::::::::.:::.:. NP_001 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ 130 140 150 160 170 180 pF1KB6 K : NP_001 K >>NP_001019397 (OMIM: 103180) ADP-ribosylation factor 1 (181 aa) initn: 1153 init1: 1153 opt: 1153 Z-score: 1169.4 bits: 223.0 E(85289): 2.1e-58 Smith-Waterman score: 1153; 96.1% identity (100.0% similar) in 181 aa overlap (1-181:1-181) 10 20 30 40 50 60 pF1KB6 MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :::::.::.:.:.::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNK :::::::::::::::::::::::::::::::::::::::::::::::::::::.:::.:. NP_001 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ 130 140 150 160 170 180 pF1KB6 K : NP_001 K >>NP_001019398 (OMIM: 103180) ADP-ribosylation factor 1 (181 aa) initn: 1153 init1: 1153 opt: 1153 Z-score: 1169.4 bits: 223.0 E(85289): 2.1e-58 Smith-Waterman score: 1153; 96.1% identity (100.0% similar) in 181 aa overlap (1-181:1-181) 10 20 30 40 50 60 pF1KB6 MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :::::.::.:.:.::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MGNIFANLFKGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNK :::::::::::::::::::::::::::::::::::::::::::::::::::::.:::.:. NP_001 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLSNQLRNQ 130 140 150 160 170 180 pF1KB6 K : NP_001 K >>NP_001651 (OMIM: 601177) ADP-ribosylation factor 4 [Ho (180 aa) initn: 960 init1: 960 opt: 960 Z-score: 977.1 bits: 187.4 E(85289): 1.1e-47 Smith-Waterman score: 960; 78.9% identity (94.4% similar) in 180 aa overlap (1-180:1-180) 10 20 30 40 50 60 pF1KB6 MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :: ...:.. :.:::.::::::::::::::::::::::::::::::::::::::::::: NP_001 MGLTISSLFSRLFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV : ::::::::::.:::::.::::::::::::::::::::..:. .::..:: ::::::: NP_001 ICFTVWDVGGQDRIRPLWKHYFQNTQGLIFVVDSNDRERIQEVADELQKMLLVDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNK ::.::::::::::: .:.::::::.:::.:.::.::::::.: :::::::::.:.:... NP_001 LLLFANKQDLPNAMAISEMTDKLGLQSLRNRTWYVQATCATQGTGLYEGLDWLSNELSKR 130 140 150 160 170 180 pF1KB6 K >>NP_001653 (OMIM: 103188) ADP-ribosylation factor 5 [Ho (180 aa) initn: 957 init1: 957 opt: 957 Z-score: 974.1 bits: 186.8 E(85289): 1.6e-47 Smith-Waterman score: 957; 78.9% identity (93.3% similar) in 180 aa overlap (1-180:1-180) 10 20 30 40 50 60 pF1KB6 MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :: . :.. ..:::.::::::::::::::::::::::::::::::::::::::::::: NP_001 MGLTVSALFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV : ::::::::::::::::::::::::::::::::::::::.:. .::..:: :::::::: NP_001 ICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESADELQKMLQEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNK :::::::::.:::: ..:.::::::. :: :.::.::::::.: :::.:::::...:... NP_001 LLVFANKQDMPNAMPVSELTDKLGLQHLRSRTWYVQATCATQGTGLYDGLDWLSHELSKR 130 140 150 160 170 180 pF1KB6 K >>NP_001654 (OMIM: 600464) ADP-ribosylation factor 6 [Ho (175 aa) initn: 878 init1: 836 opt: 860 Z-score: 877.6 bits: 168.9 E(85289): 3.8e-42 Smith-Waterman score: 860; 69.5% identity (90.2% similar) in 174 aa overlap (6-179:2-175) 10 20 30 40 50 60 pF1KB6 MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :..:....:.:::::::.:::::::::::::::::. ::::::.::::::: ::: NP_001 MGKVLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKN 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV ..:.:::::::::::::::::. .::::::::: ::.:..:::.:: :.. . :.:::. NP_001 VKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAI 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNK .:.::::::::.::. :: .:::: .: ::::.: .:::::::::::: ::... :. NP_001 ILIFANKQDLPDAMKPHEIQEKLGLTRIRDRNWYVQPSCATSGDGLYEGLTWLTSNYKS 120 130 140 150 160 170 pF1KB6 K >>XP_006719454 (OMIM: 103190) PREDICTED: ADP-ribosylatio (137 aa) initn: 822 init1: 822 opt: 822 Z-score: 840.9 bits: 161.8 E(85289): 4.2e-40 Smith-Waterman score: 822; 100.0% identity (100.0% similar) in 128 aa overlap (1-128:1-128) 10 20 30 40 50 60 pF1KB6 MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNK :::::::: XP_006 LLVFANKQVPEQSLRPG 130 181 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 14:35:32 2016 done: Fri Nov 4 14:35:33 2016 Total Scan time: 5.420 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]