Result of FASTA (omim) for
pF1KB6884
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6884, 201 aa
1>>>pF1KB6884 201 - 201 aa - 201 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0872+/-0.000298; mu= 14.8813+/- 0.019
mean_var=66.1006+/-13.153, 0's: 0 Z-trim(116.9): 53 B-trim: 1083 in 1/53
Lambda= 0.157751
statistics sampled from 28290 (28352) to 28290 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.721), E-opt: 0.2 (0.332), width: 16
Scan time: 5.150
The best scores are: opt bits E(85289)
NP_003177 (OMIM: 600818) transgelin [Homo sapiens] ( 201) 1353 316.1 2.4e-86
NP_001001522 (OMIM: 600818) transgelin [Homo sapie ( 201) 1353 316.1 2.4e-86
NP_037391 (OMIM: 607953) transgelin-3 [Homo sapien ( 199) 940 222.1 4.6e-58
NP_001008274 (OMIM: 607953) transgelin-3 [Homo sap ( 199) 940 222.1 4.6e-58
NP_001008273 (OMIM: 607953) transgelin-3 [Homo sap ( 199) 940 222.1 4.6e-58
NP_001264152 (OMIM: 604634) transgelin-2 isoform b ( 199) 919 217.3 1.3e-56
NP_003555 (OMIM: 604634) transgelin-2 isoform b [H ( 199) 919 217.3 1.3e-56
NP_001264153 (OMIM: 604634) transgelin-2 isoform a ( 220) 919 217.4 1.4e-56
NP_001272985 (OMIM: 602374) calponin-3 isoform 3 [ ( 288) 374 93.4 3.7e-19
XP_016855734 (OMIM: 602374) PREDICTED: calponin-3 ( 288) 374 93.4 3.7e-19
NP_001830 (OMIM: 602374) calponin-3 isoform 1 [Hom ( 329) 374 93.5 4.2e-19
NP_004359 (OMIM: 602373) calponin-2 isoform a [Hom ( 309) 323 81.8 1.2e-15
NP_001295271 (OMIM: 600806) calponin-1 isoform 2 [ ( 247) 301 76.8 3.3e-14
XP_005259798 (OMIM: 600806) PREDICTED: calponin-1 ( 247) 301 76.8 3.3e-14
NP_001295270 (OMIM: 600806) calponin-1 isoform 2 [ ( 247) 301 76.8 3.3e-14
XP_016881778 (OMIM: 600806) PREDICTED: calponin-1 ( 363) 301 76.9 4.5e-14
NP_958434 (OMIM: 602373) calponin-2 isoform b [Hom ( 270) 251 65.4 9.5e-11
NP_001272984 (OMIM: 602374) calponin-3 isoform 2 [ ( 283) 217 57.7 2.1e-08
NP_001290428 (OMIM: 602373) calponin-2 isoform c [ ( 298) 184 50.2 4e-06
NP_001290430 (OMIM: 602373) calponin-2 isoform d [ ( 330) 184 50.2 4.3e-06
NP_001290 (OMIM: 600806) calponin-1 isoform 1 [Hom ( 297) 179 49.0 8.8e-06
NP_001245136 (OMIM: 164875) proto-oncogene vav iso ( 813) 155 43.9 0.00087
XP_005259699 (OMIM: 164875) PREDICTED: proto-oncog ( 821) 155 43.9 0.00087
NP_001245135 (OMIM: 164875) proto-oncogene vav iso ( 823) 155 43.9 0.00087
NP_005419 (OMIM: 164875) proto-oncogene vav isofor ( 845) 155 43.9 0.00089
>>NP_003177 (OMIM: 600818) transgelin [Homo sapiens] (201 aa)
initn: 1353 init1: 1353 opt: 1353 Z-score: 1671.3 bits: 316.1 E(85289): 2.4e-86
Smith-Waterman score: 1353; 100.0% identity (100.0% similar) in 201 aa overlap (1-201:1-201)
10 20 30 40 50 60
pF1KB6 MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 ILSKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ILSKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQMG
130 140 150 160 170 180
190 200
pF1KB6 SNRGASQAGMTGYGRPRQIIS
:::::::::::::::::::::
NP_003 SNRGASQAGMTGYGRPRQIIS
190 200
>>NP_001001522 (OMIM: 600818) transgelin [Homo sapiens] (201 aa)
initn: 1353 init1: 1353 opt: 1353 Z-score: 1671.3 bits: 316.1 E(85289): 2.4e-86
Smith-Waterman score: 1353; 100.0% identity (100.0% similar) in 201 aa overlap (1-201:1-201)
10 20 30 40 50 60
pF1KB6 MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 ILSKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILSKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQMG
130 140 150 160 170 180
190 200
pF1KB6 SNRGASQAGMTGYGRPRQIIS
:::::::::::::::::::::
NP_001 SNRGASQAGMTGYGRPRQIIS
190 200
>>NP_037391 (OMIM: 607953) transgelin-3 [Homo sapiens] (199 aa)
initn: 929 init1: 591 opt: 940 Z-score: 1163.3 bits: 222.1 E(85289): 4.6e-58
Smith-Waterman score: 940; 67.7% identity (88.1% similar) in 201 aa overlap (1-200:1-199)
10 20 30 40 50 60
pF1KB6 MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGV
:::.:::::.::::: :::.::: .::..::.:::.::. :. .: :: :: :: .:.
NP_037 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT
10 20 30 40 50 60
70 80 90 100 110
pF1KB6 ILSKLVNSLYPDGSKPV-KVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFE
.: ::.::::: :..:. :. :. .:.::::::..::::::: ::: ::.::::::.:
NP_037 VLCKLINSLYPPGQEPIPKISES--KMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWE
70 80 90 100 110
120 130 140 150 160 170
pF1KB6 GKDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQM
::::::::::::::::.::::.:: :::.:.:: .:::...: :.: ::..:..::::::
NP_037 GKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQM
120 130 140 150 160 170
180 190 200
pF1KB6 GSNRGASQAGMTGYGRPRQIIS
:::.::::::::::: ::::.
NP_037 GSNKGASQAGMTGYGMPRQIM
180 190
>>NP_001008274 (OMIM: 607953) transgelin-3 [Homo sapiens (199 aa)
initn: 929 init1: 591 opt: 940 Z-score: 1163.3 bits: 222.1 E(85289): 4.6e-58
Smith-Waterman score: 940; 67.7% identity (88.1% similar) in 201 aa overlap (1-200:1-199)
10 20 30 40 50 60
pF1KB6 MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGV
:::.:::::.::::: :::.::: .::..::.:::.::. :. .: :: :: :: .:.
NP_001 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT
10 20 30 40 50 60
70 80 90 100 110
pF1KB6 ILSKLVNSLYPDGSKPV-KVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFE
.: ::.::::: :..:. :. :. .:.::::::..::::::: ::: ::.::::::.:
NP_001 VLCKLINSLYPPGQEPIPKISES--KMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWE
70 80 90 100 110
120 130 140 150 160 170
pF1KB6 GKDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQM
::::::::::::::::.::::.:: :::.:.:: .:::...: :.: ::..:..::::::
NP_001 GKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQM
120 130 140 150 160 170
180 190 200
pF1KB6 GSNRGASQAGMTGYGRPRQIIS
:::.::::::::::: ::::.
NP_001 GSNKGASQAGMTGYGMPRQIM
180 190
>>NP_001008273 (OMIM: 607953) transgelin-3 [Homo sapiens (199 aa)
initn: 929 init1: 591 opt: 940 Z-score: 1163.3 bits: 222.1 E(85289): 4.6e-58
Smith-Waterman score: 940; 67.7% identity (88.1% similar) in 201 aa overlap (1-200:1-199)
10 20 30 40 50 60
pF1KB6 MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGV
:::.:::::.::::: :::.::: .::..::.:::.::. :. .: :: :: :: .:.
NP_001 MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGT
10 20 30 40 50 60
70 80 90 100 110
pF1KB6 ILSKLVNSLYPDGSKPV-KVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFE
.: ::.::::: :..:. :. :. .:.::::::..::::::: ::: ::.::::::.:
NP_001 VLCKLINSLYPPGQEPIPKISES--KMAFKQMEQISQFLKAAETYGVRTTDIFQTVDLWE
70 80 90 100 110
120 130 140 150 160 170
pF1KB6 GKDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQM
::::::::::::::::.::::.:: :::.:.:: .:::...: :.: ::..:..::::::
NP_001 GKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQM
120 130 140 150 160 170
180 190 200
pF1KB6 GSNRGASQAGMTGYGRPRQIIS
:::.::::::::::: ::::.
NP_001 GSNKGASQAGMTGYGMPRQIM
180 190
>>NP_001264152 (OMIM: 604634) transgelin-2 isoform b [Ho (199 aa)
initn: 930 init1: 567 opt: 919 Z-score: 1137.5 bits: 217.3 E(85289): 1.3e-56
Smith-Waterman score: 919; 65.0% identity (87.5% similar) in 200 aa overlap (1-200:1-199)
10 20 30 40 50 60
pF1KB6 MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGV
:::.::.::.:::::.::::.:: .::. :..:: .:: :::::. :: .:: :::.:.
NP_001 MANRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 ILSKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEG
.: .:.:.:::.:. ::: . .:.::::::..:::.::: ::. ::.::::::.::
NP_001 VLCELINALYPEGQAPVKKIQAS-TMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEG
70 80 90 100 110
130 140 150 160 170 180
pF1KB6 KDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQMG
:.:: :::::: ::.:::...:: . :::::: ::..:. :.:...::::::.:::::::
NP_001 KNMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMG
120 130 140 150 160 170
190 200
pF1KB6 SNRGASQAGMTGYGRPRQIIS
.::::::::::::: ::::.
NP_001 TNRGASQAGMTGYGMPRQIL
180 190
>>NP_003555 (OMIM: 604634) transgelin-2 isoform b [Homo (199 aa)
initn: 930 init1: 567 opt: 919 Z-score: 1137.5 bits: 217.3 E(85289): 1.3e-56
Smith-Waterman score: 919; 65.0% identity (87.5% similar) in 200 aa overlap (1-200:1-199)
10 20 30 40 50 60
pF1KB6 MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGV
:::.::.::.:::::.::::.:: .::. :..:: .:: :::::. :: .:: :::.:.
NP_003 MANRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 ILSKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEG
.: .:.:.:::.:. ::: . .:.::::::..:::.::: ::. ::.::::::.::
NP_003 VLCELINALYPEGQAPVKKIQAS-TMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEG
70 80 90 100 110
130 140 150 160 170 180
pF1KB6 KDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQMG
:.:: :::::: ::.:::...:: . :::::: ::..:. :.:...::::::.:::::::
NP_003 KNMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKENPRNFSDNQLQEGKNVIGLQMG
120 130 140 150 160 170
190 200
pF1KB6 SNRGASQAGMTGYGRPRQIIS
.::::::::::::: ::::.
NP_003 TNRGASQAGMTGYGMPRQIL
180 190
>>NP_001264153 (OMIM: 604634) transgelin-2 isoform a [Ho (220 aa)
initn: 914 init1: 567 opt: 919 Z-score: 1136.9 bits: 217.4 E(85289): 1.4e-56
Smith-Waterman score: 919; 65.0% identity (87.5% similar) in 200 aa overlap (1-200:22-220)
10 20 30
pF1KB6 MANKGPSYGMSREVQSKIEKKYDEELEERLVEWIIVQCG
:::.::.::.:::::.::::.:: .::. :..:: .::
NP_001 MSAFSLALALVSSPQPPPPIGMANRGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCR
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB6 PDVGRPDRGRLGFQVWLKNGVILSKLVNSLYPDGSKPVKVPENPPSMVFKQMEQVAQFLK
:::::. :: .:: :::.:..: .:.:.:::.:. ::: . .:.::::::..:::.
NP_001 KDVGRPQPGRENFQNWLKDGTVLCELINALYPEGQAPVKKIQAS-TMAFKQMEQISQFLQ
70 80 90 100 110
100 110 120 130 140 150
pF1KB6 AAEDYGVIKTDMFQTVDLFEGKDMAAVQRTLMALGSLAVTKNDGHYRGDPNWFMKKAQEH
::: ::. ::.::::::.:::.:: :::::: ::.:::...:: . :::::: ::..:.
NP_001 AAERYGINTTDIFQTVDLWEGKNMACVQRTLMNLGGLAVARDDGLFSGDPNWFPKKSKEN
120 130 140 150 160 170
160 170 180 190 200
pF1KB6 KREFTESQLQEGKHVIGLQMGSNRGASQAGMTGYGRPRQIIS
:.:...::::::.:::::::.::::::::::::: ::::.
NP_001 PRNFSDNQLQEGKNVIGLQMGTNRGASQAGMTGYGMPRQIL
180 190 200 210 220
>>NP_001272985 (OMIM: 602374) calponin-3 isoform 3 [Homo (288 aa)
initn: 497 init1: 161 opt: 374 Z-score: 464.9 bits: 93.4 E(85289): 3.7e-19
Smith-Waterman score: 374; 44.6% identity (73.0% similar) in 148 aa overlap (52-199:7-147)
30 40 50 60 70 80
pF1KB6 YDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGVILSKLVNSLYPDGSKPVKVPE
::. ::.:.:: .:.:.: : . : :
NP_001 MSIGPNFQLGLKDGIILCELINKLQPGSVKKV----
10 20 30
90 100 110 120 130 140
pF1KB6 NPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEGKDMAAVQRTLMALGSLAVTKN
: :. . :.:....:.:: . ::. :.:.. ::::. .:. :: ::.::..:: ::.
NP_001 NESSLNWPQLENIGNFIKAIQAYGMKPHDIFEANDLFENGNMTQVQTTLVALAGLAKTKG
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB6 DGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQMGSNRGASQAGMTGYGRPRQIIS
: : . .: :... :.: :..:. :. :::::::.:. :::::::.:: :..
NP_001 -FHTTIDIG--VKYAEKQTRRFDEGKLKAGQSVIGLQMGTNKCASQAGMTAYGTRRHLYD
100 110 120 130 140
NP_001 PKMQTDKPFDQTTISLQMGTNKGASQAGMLAPGTRRDIYDQKLTLQPVDNSTISLQMGTN
150 160 170 180 190 200
>>XP_016855734 (OMIM: 602374) PREDICTED: calponin-3 isof (288 aa)
initn: 497 init1: 161 opt: 374 Z-score: 464.9 bits: 93.4 E(85289): 3.7e-19
Smith-Waterman score: 374; 44.6% identity (73.0% similar) in 148 aa overlap (52-199:7-147)
30 40 50 60 70 80
pF1KB6 YDEELEERLVEWIIVQCGPDVGRPDRGRLGFQVWLKNGVILSKLVNSLYPDGSKPVKVPE
::. ::.:.:: .:.:.: : . : :
XP_016 MSIGPNFQLGLKDGIILCELINKLQPGSVKKV----
10 20 30
90 100 110 120 130 140
pF1KB6 NPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLFEGKDMAAVQRTLMALGSLAVTKN
: :. . :.:....:.:: . ::. :.:.. ::::. .:. :: ::.::..:: ::.
XP_016 NESSLNWPQLENIGNFIKAIQAYGMKPHDIFEANDLFENGNMTQVQTTLVALAGLAKTKG
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB6 DGHYRGDPNWFMKKAQEHKREFTESQLQEGKHVIGLQMGSNRGASQAGMTGYGRPRQIIS
: : . .: :... :.: :..:. :. :::::::.:. :::::::.:: :..
XP_016 -FHTTIDIG--VKYAEKQTRRFDEGKLKAGQSVIGLQMGTNKCASQAGMTAYGTRRHLYD
100 110 120 130 140
XP_016 PKMQTDKPFDQTTISLQMGTNKGASQAGMLAPGTRRDIYDQKLTLQPVDNSTISLQMGTN
150 160 170 180 190 200
201 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 14:02:36 2016 done: Fri Nov 4 14:02:37 2016
Total Scan time: 5.150 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]