FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6885, 180 aa 1>>>pF1KB6885 180 - 180 aa - 180 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.6465+/-0.00056; mu= 17.2603+/- 0.034 mean_var=63.8130+/-12.414, 0's: 0 Z-trim(113.5): 8 B-trim: 62 in 1/53 Lambda= 0.160553 statistics sampled from 14123 (14130) to 14123 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.799), E-opt: 0.2 (0.434), width: 16 Scan time: 2.160 The best scores are: opt bits E(32554) CCDS7728.1 IGF2 gene_id:3481|Hs108|chr11 ( 180) 1245 295.8 9.4e-81 CCDS44517.1 IGF2 gene_id:3481|Hs108|chr11 ( 236) 1245 295.9 1.2e-80 CCDS44961.1 IGF1 gene_id:3479|Hs108|chr12 ( 158) 319 81.3 3.2e-16 CCDS44960.1 IGF1 gene_id:3479|Hs108|chr12 ( 137) 317 80.8 3.9e-16 CCDS9091.1 IGF1 gene_id:3479|Hs108|chr12 ( 153) 317 80.8 4.3e-16 >>CCDS7728.1 IGF2 gene_id:3481|Hs108|chr11 (180 aa) initn: 1245 init1: 1245 opt: 1245 Z-score: 1563.2 bits: 295.8 E(32554): 9.4e-81 Smith-Waterman score: 1245; 100.0% identity (100.0% similar) in 180 aa overlap (1-180:1-180) 10 20 30 40 50 60 pF1KB6 MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS77 QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK 130 140 150 160 170 180 >>CCDS44517.1 IGF2 gene_id:3481|Hs108|chr11 (236 aa) initn: 1245 init1: 1245 opt: 1245 Z-score: 1561.6 bits: 295.9 E(32554): 1.2e-80 Smith-Waterman score: 1245; 100.0% identity (100.0% similar) in 180 aa overlap (1-180:57-236) 10 20 30 pF1KB6 MGIPMGKSMLVLLTFLAFASCCIAAYRPSE :::::::::::::::::::::::::::::: CCDS44 DGVTIIQIFWVGRKGELLRRTPVSSAMQTPMGIPMGKSMLVLLTFLAFASCCIAAYRPSE 30 40 50 60 70 80 40 50 60 70 80 90 pF1KB6 TLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSRGIVEECCFRSCDLALLETYCATPAKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 TLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSRGIVEECCFRSCDLALLETYCATPAKS 90 100 110 120 130 140 100 110 120 130 140 150 pF1KB6 ERDVSTPPTVLPDNFPRYPVGKFFQYDTWKQSTQRLRRGLPALLRARRGHVLAKELEAFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 ERDVSTPPTVLPDNFPRYPVGKFFQYDTWKQSTQRLRRGLPALLRARRGHVLAKELEAFR 150 160 170 180 190 200 160 170 180 pF1KB6 EAKRHRPLIALPTQDPAHGGAPPEMASNRK :::::::::::::::::::::::::::::: CCDS44 EAKRHRPLIALPTQDPAHGGAPPEMASNRK 210 220 230 >>CCDS44961.1 IGF1 gene_id:3479|Hs108|chr12 (158 aa) initn: 310 init1: 172 opt: 319 Z-score: 404.8 bits: 81.3 E(32554): 3.2e-16 Smith-Waterman score: 319; 47.0% identity (66.7% similar) in 132 aa overlap (5-128:27-149) 10 20 30 pF1KB6 MGIPMGKSMLVLLTF--LAFASCCIAAYRPSETLCGGE :..: : :.. :.:.: :. : :::::.: CCDS44 MGKISSLPTQLFKCCFCDFLKVKMHTMSSSHLFYLALCLLTFTSSATAG--P-ETLCGAE 10 20 30 40 50 40 50 60 70 80 90 pF1KB6 LVDTLQFVCGDRGFYFSRPASR--VSRRS--RGIVEECCFRSCDLALLETYCAT--PAKS :::.::::::::::::..:.. :::. :::.::::::::: :: ::: :::: CCDS44 LVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKS 60 70 80 90 100 110 100 110 120 130 140 150 pF1KB6 ERDVSTPPTVLPDNFPRYPVGKFFQYDTWKQSTQRLRRGLPALLRARRGHVLAKELEAFR :.: . . .: . .: . ...:. :: CCDS44 ARSVRA------QRHTDMPKTQKYQPPSTNKNTKSQRRKGSTFEERK 120 130 140 150 160 170 180 pF1KB6 EAKRHRPLIALPTQDPAHGGAPPEMASNRK >>CCDS44960.1 IGF1 gene_id:3479|Hs108|chr12 (137 aa) initn: 319 init1: 168 opt: 317 Z-score: 403.1 bits: 80.8 E(32554): 3.9e-16 Smith-Waterman score: 317; 58.2% identity (74.5% similar) in 98 aa overlap (5-94:11-105) 10 20 30 40 50 pF1KB6 MGIPMGKSMLVLLTF--LAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYF :..: : :.. :.:.: :. : :::::.::::.:::::::::::: CCDS44 MITPTVKMHTMSSSHLFYLALCLLTFTSSATAG--P-ETLCGAELVDALQFVCGDRGFYF 10 20 30 40 50 60 70 80 90 100 pF1KB6 SRPASR--VSRRS--RGIVEECCFRSCDLALLETYCAT--PAKSERDVSTPPTVLPDNFP ..:.. :::. :::.::::::::: :: ::: :::: :.: CCDS44 NKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARSVRAQRHTDMPKTQ 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB6 RYPVGKFFQYDTWKQSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDP CCDS44 KEVHLKNASRGSAGNKNYRM 120 130 >>CCDS9091.1 IGF1 gene_id:3479|Hs108|chr12 (153 aa) initn: 306 init1: 168 opt: 317 Z-score: 402.5 bits: 80.8 E(32554): 4.3e-16 Smith-Waterman score: 317; 58.2% identity (74.5% similar) in 98 aa overlap (5-94:27-121) 10 20 30 pF1KB6 MGIPMGKSMLVLLTF--LAFASCCIAAYRPSETLCGGE :..: : :.. :.:.: :. : :::::.: CCDS90 MGKISSLPTQLFKCCFCDFLKVKMHTMSSSHLFYLALCLLTFTSSATAG--P-ETLCGAE 10 20 30 40 50 40 50 60 70 80 90 pF1KB6 LVDTLQFVCGDRGFYFSRPASR--VSRRS--RGIVEECCFRSCDLALLETYCAT--PAKS :::.::::::::::::..:.. :::. :::.::::::::: :: ::: :::: CCDS90 LVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKS 60 70 80 90 100 110 100 110 120 130 140 150 pF1KB6 ERDVSTPPTVLPDNFPRYPVGKFFQYDTWKQSTQRLRRGLPALLRARRGHVLAKELEAFR :.: CCDS90 ARSVRAQRHTDMPKTQKEVHLKNASRGSAGNKNYRM 120 130 140 150 180 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 15:01:25 2016 done: Fri Nov 4 15:01:25 2016 Total Scan time: 2.160 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]