Result of FASTA (omim) for
pF1KB6885
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6885, 180 aa
1>>>pF1KB6885 180 - 180 aa - 180 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8310+/-0.000271; mu= 16.0174+/- 0.017
mean_var=63.1013+/-12.466, 0's: 0 Z-trim(120.3): 17 B-trim: 212 in 1/56
Lambda= 0.161456
statistics sampled from 35338 (35356) to 35338 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.783), E-opt: 0.2 (0.415), width: 16
Scan time: 6.230
The best scores are: opt bits E(85289)
NP_001007140 (OMIM: 130650,147470,180860,194070,61 ( 180) 1245 297.5 7.6e-81
NP_000603 (OMIM: 130650,147470,180860,194070,61648 ( 180) 1245 297.5 7.6e-81
NP_001278790 (OMIM: 130650,147470,180860,194070,61 ( 180) 1245 297.5 7.6e-81
NP_001278791 (OMIM: 130650,147470,180860,194070,61 ( 180) 1245 297.5 7.6e-81
NP_001121070 (OMIM: 130650,147470,180860,194070,61 ( 236) 1245 297.6 9.4e-81
XP_016874750 (OMIM: 147440,608747) PREDICTED: insu ( 179) 327 83.7 1.8e-16
NP_001104755 (OMIM: 147440,608747) insulin-like gr ( 195) 327 83.7 1.9e-16
XP_016874748 (OMIM: 147440,608747) PREDICTED: insu ( 212) 327 83.7 2e-16
NP_001104753 (OMIM: 147440,608747) insulin-like gr ( 158) 319 81.8 5.9e-16
XP_016874751 (OMIM: 147440,608747) PREDICTED: insu ( 175) 319 81.8 6.3e-16
NP_001104754 (OMIM: 147440,608747) insulin-like gr ( 137) 317 81.3 7.2e-16
NP_000609 (OMIM: 147440,608747) insulin-like growt ( 153) 317 81.3 7.9e-16
XP_016874752 (OMIM: 147440,608747) PREDICTED: insu ( 170) 317 81.3 8.6e-16
>>NP_001007140 (OMIM: 130650,147470,180860,194070,616489 (180 aa)
initn: 1245 init1: 1245 opt: 1245 Z-score: 1572.4 bits: 297.5 E(85289): 7.6e-81
Smith-Waterman score: 1245; 100.0% identity (100.0% similar) in 180 aa overlap (1-180:1-180)
10 20 30 40 50 60
pF1KB6 MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK
130 140 150 160 170 180
>>NP_000603 (OMIM: 130650,147470,180860,194070,616489) i (180 aa)
initn: 1245 init1: 1245 opt: 1245 Z-score: 1572.4 bits: 297.5 E(85289): 7.6e-81
Smith-Waterman score: 1245; 100.0% identity (100.0% similar) in 180 aa overlap (1-180:1-180)
10 20 30 40 50 60
pF1KB6 MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK
130 140 150 160 170 180
>>NP_001278790 (OMIM: 130650,147470,180860,194070,616489 (180 aa)
initn: 1245 init1: 1245 opt: 1245 Z-score: 1572.4 bits: 297.5 E(85289): 7.6e-81
Smith-Waterman score: 1245; 100.0% identity (100.0% similar) in 180 aa overlap (1-180:1-180)
10 20 30 40 50 60
pF1KB6 MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK
130 140 150 160 170 180
>>NP_001278791 (OMIM: 130650,147470,180860,194070,616489 (180 aa)
initn: 1245 init1: 1245 opt: 1245 Z-score: 1572.4 bits: 297.5 E(85289): 7.6e-81
Smith-Waterman score: 1245; 100.0% identity (100.0% similar) in 180 aa overlap (1-180:1-180)
10 20 30 40 50 60
pF1KB6 MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGIPMGKSMLVLLTFLAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYFSRPASRVS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK
130 140 150 160 170 180
>>NP_001121070 (OMIM: 130650,147470,180860,194070,616489 (236 aa)
initn: 1245 init1: 1245 opt: 1245 Z-score: 1570.8 bits: 297.6 E(85289): 9.4e-81
Smith-Waterman score: 1245; 100.0% identity (100.0% similar) in 180 aa overlap (1-180:57-236)
10 20 30
pF1KB6 MGIPMGKSMLVLLTFLAFASCCIAAYRPSE
::::::::::::::::::::::::::::::
NP_001 DGVTIIQIFWVGRKGELLRRTPVSSAMQTPMGIPMGKSMLVLLTFLAFASCCIAAYRPSE
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB6 TLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSRGIVEECCFRSCDLALLETYCATPAKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLCGGELVDTLQFVCGDRGFYFSRPASRVSRRSRGIVEECCFRSCDLALLETYCATPAKS
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB6 ERDVSTPPTVLPDNFPRYPVGKFFQYDTWKQSTQRLRRGLPALLRARRGHVLAKELEAFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERDVSTPPTVLPDNFPRYPVGKFFQYDTWKQSTQRLRRGLPALLRARRGHVLAKELEAFR
150 160 170 180 190 200
160 170 180
pF1KB6 EAKRHRPLIALPTQDPAHGGAPPEMASNRK
::::::::::::::::::::::::::::::
NP_001 EAKRHRPLIALPTQDPAHGGAPPEMASNRK
210 220 230
>>XP_016874750 (OMIM: 147440,608747) PREDICTED: insulin- (179 aa)
initn: 310 init1: 172 opt: 327 Z-score: 416.8 bits: 83.7 E(85289): 1.8e-16
Smith-Waterman score: 327; 47.4% identity (68.9% similar) in 135 aa overlap (5-131:11-137)
10 20 30 40 50
pF1KB6 MGIPMGKSMLVLLTF--LAFASCCIAAYRPSETLCGGELVDTLQFVCGDRGFYF
:..: : :.. :.:.: :. : :::::.::::.::::::::::::
XP_016 MITPTVKMHTMSSSHLFYLALCLLTFTSSATAG--P-ETLCGAELVDALQFVCGDRGFYF
10 20 30 40 50
60 70 80 90 100
pF1KB6 SRPASR--VSRRS--RGIVEECCFRSCDLALLETYCAT--PAKSERDVSTPPTVLPDNFP
..:.. :::. :::.::::::::: :: ::: :::: :.: . . ..:
XP_016 NKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARSVRAQRHT---DMP
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB6 RYPVGKFFQYDTWKQSTQRLRRGLPALLRARRGHVLAKELEAFREAKRHRPLIALPTQDP
. . :. .: :.. .. :.: :
XP_016 K--TQKYQPPSTNKNTKSQRRKGWPKTHPGGEQKEGTEASLQIRGKKKEQRREIGSRNAE
120 130 140 150 160 170
>>NP_001104755 (OMIM: 147440,608747) insulin-like growth (195 aa)
initn: 310 init1: 172 opt: 327 Z-score: 416.3 bits: 83.7 E(85289): 1.9e-16
Smith-Waterman score: 327; 47.4% identity (68.9% similar) in 135 aa overlap (5-131:27-153)
10 20 30
pF1KB6 MGIPMGKSMLVLLTF--LAFASCCIAAYRPSETLCGGE
:..: : :.. :.:.: :. : :::::.:
NP_001 MGKISSLPTQLFKCCFCDFLKVKMHTMSSSHLFYLALCLLTFTSSATAG--P-ETLCGAE
10 20 30 40 50
40 50 60 70 80 90
pF1KB6 LVDTLQFVCGDRGFYFSRPASR--VSRRS--RGIVEECCFRSCDLALLETYCAT--PAKS
:::.::::::::::::..:.. :::. :::.::::::::: :: ::: ::::
NP_001 LVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKS
60 70 80 90 100 110
100 110 120 130 140 150
pF1KB6 ERDVSTPPTVLPDNFPRYPVGKFFQYDTWKQSTQRLRRGLPALLRARRGHVLAKELEAFR
:.: . . ..:. . :. .: :.. .. :.: :
NP_001 ARSVRAQRHT---DMPK--TQKYQPPSTNKNTKSQRRKGWPKTHPGGEQKEGTEASLQIR
120 130 140 150 160 170
160 170 180
pF1KB6 EAKRHRPLIALPTQDPAHGGAPPEMASNRK
NP_001 GKKKEQRREIGSRNAECRGKKGK
180 190
>>XP_016874748 (OMIM: 147440,608747) PREDICTED: insulin- (212 aa)
initn: 310 init1: 172 opt: 327 Z-score: 415.8 bits: 83.7 E(85289): 2e-16
Smith-Waterman score: 327; 47.4% identity (68.9% similar) in 135 aa overlap (5-131:44-170)
10 20 30
pF1KB6 MGIPMGKSMLVLLTF--LAFASCCIAAYRPSETL
:..: : :.. :.:.: :. : :::
XP_016 KKKFKVQVISTTPGKPGLESSLGKEVKMHTMSSSHLFYLALCLLTFTSSATAG--P-ETL
20 30 40 50 60 70
40 50 60 70 80
pF1KB6 CGGELVDTLQFVCGDRGFYFSRPASR--VSRRS--RGIVEECCFRSCDLALLETYCAT--
::.::::.::::::::::::..:.. :::. :::.::::::::: :: :::
XP_016 CGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLK
80 90 100 110 120 130
90 100 110 120 130 140
pF1KB6 PAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWKQSTQRLRRGLPALLRARRGHVLAKEL
:::: :.: . . ..:. . :. .: :.. .. :.: :
XP_016 PAKSARSVRAQRHT---DMPK--TQKYQPPSTNKNTKSQRRKGWPKTHPGGEQKEGTEAS
140 150 160 170 180
150 160 170 180
pF1KB6 EAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK
XP_016 LQIRGKKKEQRREIGSRNAECRGKKGK
190 200 210
>>NP_001104753 (OMIM: 147440,608747) insulin-like growth (158 aa)
initn: 310 init1: 172 opt: 319 Z-score: 407.5 bits: 81.8 E(85289): 5.9e-16
Smith-Waterman score: 319; 47.0% identity (66.7% similar) in 132 aa overlap (5-128:27-149)
10 20 30
pF1KB6 MGIPMGKSMLVLLTF--LAFASCCIAAYRPSETLCGGE
:..: : :.. :.:.: :. : :::::.:
NP_001 MGKISSLPTQLFKCCFCDFLKVKMHTMSSSHLFYLALCLLTFTSSATAG--P-ETLCGAE
10 20 30 40 50
40 50 60 70 80 90
pF1KB6 LVDTLQFVCGDRGFYFSRPASR--VSRRS--RGIVEECCFRSCDLALLETYCAT--PAKS
:::.::::::::::::..:.. :::. :::.::::::::: :: ::: ::::
NP_001 LVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKS
60 70 80 90 100 110
100 110 120 130 140 150
pF1KB6 ERDVSTPPTVLPDNFPRYPVGKFFQYDTWKQSTQRLRRGLPALLRARRGHVLAKELEAFR
:.: . . .: . .: . ...:. ::
NP_001 ARSVRA------QRHTDMPKTQKYQPPSTNKNTKSQRRKGSTFEERK
120 130 140 150
160 170 180
pF1KB6 EAKRHRPLIALPTQDPAHGGAPPEMASNRK
>>XP_016874751 (OMIM: 147440,608747) PREDICTED: insulin- (175 aa)
initn: 310 init1: 172 opt: 319 Z-score: 406.9 bits: 81.8 E(85289): 6.3e-16
Smith-Waterman score: 319; 47.0% identity (66.7% similar) in 132 aa overlap (5-128:44-166)
10 20 30
pF1KB6 MGIPMGKSMLVLLTF--LAFASCCIAAYRPSETL
:..: : :.. :.:.: :. : :::
XP_016 KKKFKVQVISTTPGKPGLESSLGKEVKMHTMSSSHLFYLALCLLTFTSSATAG--P-ETL
20 30 40 50 60 70
40 50 60 70 80
pF1KB6 CGGELVDTLQFVCGDRGFYFSRPASR--VSRRS--RGIVEECCFRSCDLALLETYCAT--
::.::::.::::::::::::..:.. :::. :::.::::::::: :: :::
XP_016 CGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLK
80 90 100 110 120 130
90 100 110 120 130 140
pF1KB6 PAKSERDVSTPPTVLPDNFPRYPVGKFFQYDTWKQSTQRLRRGLPALLRARRGHVLAKEL
:::: :.: . . .: . .: . ...:. ::
XP_016 PAKSARSVRA------QRHTDMPKTQKYQPPSTNKNTKSQRRKGSTFEERK
140 150 160 170
150 160 170 180
pF1KB6 EAFREAKRHRPLIALPTQDPAHGGAPPEMASNRK
180 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 15:01:26 2016 done: Fri Nov 4 15:01:27 2016
Total Scan time: 6.230 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]