FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6887, 183 aa
1>>>pF1KB6887 183 - 183 aa - 183 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.4100+/-0.000283; mu= 9.6063+/- 0.018
mean_var=123.6577+/-24.837, 0's: 0 Z-trim(122.5): 9 B-trim: 2170 in 1/51
Lambda= 0.115336
statistics sampled from 40614 (40623) to 40614 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.815), E-opt: 0.2 (0.476), width: 16
Scan time: 6.300
The best scores are: opt bits E(85289)
XP_011539778 (OMIM: 156790) PREDICTED: microfibril ( 183) 1313 228.3 5.5e-60
NP_059453 (OMIM: 156790) microfibrillar-associated ( 183) 1313 228.3 5.5e-60
NP_002394 (OMIM: 156790) microfibrillar-associated ( 183) 1313 228.3 5.5e-60
NP_001128720 (OMIM: 156790) microfibrillar-associa ( 182) 1296 225.4 3.9e-59
NP_001128719 (OMIM: 156790) microfibrillar-associa ( 182) 1296 225.4 3.9e-59
NP_001284639 (OMIM: 601103,616166) microfibrillar- ( 151) 293 58.5 5.9e-09
NP_001284638 (OMIM: 601103,616166) microfibrillar- ( 163) 293 58.5 6.3e-09
NP_001284640 (OMIM: 601103,616166) microfibrillar- ( 148) 287 57.5 1.2e-08
NP_003471 (OMIM: 601103,616166) microfibrillar-ass ( 173) 283 56.8 2.1e-08
>>XP_011539778 (OMIM: 156790) PREDICTED: microfibrillar- (183 aa)
initn: 1313 init1: 1313 opt: 1313 Z-score: 1197.9 bits: 228.3 E(85289): 5.5e-60
Smith-Waterman score: 1313; 100.0% identity (100.0% similar) in 183 aa overlap (1-183:1-183)
10 20 30 40 50 60
pF1KB6 MRAAYLFLLFLPAGLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRAAYLFLLFLPAGLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 VCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSC
130 140 150 160 170 180
pF1KB6 GSC
:::
XP_011 GSC
>>NP_059453 (OMIM: 156790) microfibrillar-associated pro (183 aa)
initn: 1313 init1: 1313 opt: 1313 Z-score: 1197.9 bits: 228.3 E(85289): 5.5e-60
Smith-Waterman score: 1313; 100.0% identity (100.0% similar) in 183 aa overlap (1-183:1-183)
10 20 30 40 50 60
pF1KB6 MRAAYLFLLFLPAGLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 MRAAYLFLLFLPAGLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 QFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 VCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 VCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSC
130 140 150 160 170 180
pF1KB6 GSC
:::
NP_059 GSC
>>NP_002394 (OMIM: 156790) microfibrillar-associated pro (183 aa)
initn: 1313 init1: 1313 opt: 1313 Z-score: 1197.9 bits: 228.3 E(85289): 5.5e-60
Smith-Waterman score: 1313; 100.0% identity (100.0% similar) in 183 aa overlap (1-183:1-183)
10 20 30 40 50 60
pF1KB6 MRAAYLFLLFLPAGLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MRAAYLFLLFLPAGLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 VCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSC
130 140 150 160 170 180
pF1KB6 GSC
:::
NP_002 GSC
>>NP_001128720 (OMIM: 156790) microfibrillar-associated (182 aa)
initn: 1230 init1: 1230 opt: 1296 Z-score: 1182.6 bits: 225.4 E(85289): 3.9e-59
Smith-Waterman score: 1296; 99.5% identity (99.5% similar) in 183 aa overlap (1-183:1-182)
10 20 30 40 50 60
pF1KB6 MRAAYLFLLFLPAGLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEE
:::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRAAYLFLLFLP-GLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEE
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 QFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNE
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 VCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSC
120 130 140 150 160 170
pF1KB6 GSC
:::
NP_001 GSC
180
>>NP_001128719 (OMIM: 156790) microfibrillar-associated (182 aa)
initn: 1230 init1: 1230 opt: 1296 Z-score: 1182.6 bits: 225.4 E(85289): 3.9e-59
Smith-Waterman score: 1296; 99.5% identity (99.5% similar) in 183 aa overlap (1-183:1-182)
10 20 30 40 50 60
pF1KB6 MRAAYLFLLFLPAGLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEE
:::::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRAAYLFLLFLP-GLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEE
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 QFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNE
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 VCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSC
120 130 140 150 160 170
pF1KB6 GSC
:::
NP_001 GSC
180
>>NP_001284639 (OMIM: 601103,616166) microfibrillar-asso (151 aa)
initn: 301 init1: 288 opt: 293 Z-score: 281.7 bits: 58.5 E(85289): 5.9e-09
Smith-Waterman score: 293; 51.4% identity (80.0% similar) in 70 aa overlap (85-154:51-119)
60 70 80 90 100 110
pF1KB6 PRPSEEQFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPC
:.. :. :.: .:.. ::::::.:::
NP_001 DVTQATPETFTEDPNLVNDPATDETVLAVLADIAPSTDD-LECWDEKFTCTRLYSVHRPV
30 40 50 60 70
120 130 140 150 160 170
pF1KB6 KQCLNEVCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAA
:::....:: ::::.:..::::: : :: ..: .. .:::
NP_001 KQCIHQLCFTSLRRMYIVNKEICSRLVCKEHEAMKDELCRQMAGLPPRRLRRSNYFRLPP
80 90 100 110 120 130
180
pF1KB6 SCARSCGSC
NP_001 CENVDLQRPNGL
140 150
>>NP_001284638 (OMIM: 601103,616166) microfibrillar-asso (163 aa)
initn: 302 init1: 288 opt: 293 Z-score: 281.3 bits: 58.5 E(85289): 6.3e-09
Smith-Waterman score: 293; 51.4% identity (80.0% similar) in 70 aa overlap (85-154:63-131)
60 70 80 90 100 110
pF1KB6 PRPSEEQFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPC
:.. :. :.: .:.. ::::::.:::
NP_001 DVTQATPETFTEDPNLVNDPATDETVLAVLADIAPSTDD-LECWDEKFTCTRLYSVHRPV
40 50 60 70 80 90
120 130 140 150 160 170
pF1KB6 KQCLNEVCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAA
:::....:: ::::.:..::::: : :: ..: .. .:::
NP_001 KQCIHQLCFTSLRRMYIVNKEICSRLVCKEHEAMKDELCRQMAGLPPRRLRRSNYFRLPP
100 110 120 130 140 150
180
pF1KB6 SCARSCGSC
NP_001 CENVDLQRPNGL
160
>>NP_001284640 (OMIM: 601103,616166) microfibrillar-asso (148 aa)
initn: 297 init1: 283 opt: 287 Z-score: 276.4 bits: 57.5 E(85289): 1.2e-08
Smith-Waterman score: 287; 44.4% identity (68.9% similar) in 90 aa overlap (65-154:29-116)
40 50 60 70 80 90
pF1KB6 YTHYSDQIDNPDYYDYQEVTPRPSEEQFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGP
: ..: : . : : : .:.
NP_001 MSLLGPKVLLFLAAFIITSDWIPLGVNSQRGDDVTQ-ATPETFTEDPNLVNDPATD-E
10 20 30 40 50
100 110 120 130 140 150
pF1KB6 LDCREEQYPCTRLYSIHRPCKQCLNEVCFYSLRRVYVINKEICVRTVCAHEELLRADLCR
.: .:.. ::::::.::: :::....:: ::::.:..::::: : :: ..: .. .:::
NP_001 TECWDEKFTCTRLYSVHRPVKQCIHQLCFTSLRRMYIVNKEICSRLVCKEHEAMKDELCR
60 70 80 90 100 110
160 170 180
pF1KB6 DKFSKCGVMASSGLCQSVAASCARSCGSC
NP_001 QMAGLPPRRLRRSNYFRLPPCENVDLQRPNGL
120 130 140
>>NP_003471 (OMIM: 601103,616166) microfibrillar-associa (173 aa)
initn: 297 init1: 283 opt: 283 Z-score: 271.9 bits: 56.8 E(85289): 2.1e-08
Smith-Waterman score: 283; 55.9% identity (84.7% similar) in 59 aa overlap (96-154:83-141)
70 80 90 100 110 120
pF1KB6 SQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNEVCFYS
.: .:.. ::::::.::: :::....:: :
NP_003 ATDETVLAVLADIAPSTDDLASLSEKNTTAECWDEKFTCTRLYSVHRPVKQCIHQLCFTS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 LRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSCGSC
:::.:..::::: : :: ..: .. .:::
NP_003 LRRMYIVNKEICSRLVCKEHEAMKDELCRQMAGLPPRRLRRSNYFRLPPCENVDLQRPNG
120 130 140 150 160 170
183 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 00:12:22 2016 done: Sat Nov 5 00:12:23 2016
Total Scan time: 6.300 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]