FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6891, 183 aa
  1>>>pF1KB6891 183 - 183 aa - 183 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.9020+/-0.000378; mu= 9.8928+/- 0.024
 mean_var=71.3379+/-14.689, 0's: 0 Z-trim(113.2): 13  B-trim: 821 in 1/47
 Lambda= 0.151850
 statistics sampled from 22445 (22449) to 22445 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.65), E-opt: 0.2 (0.263), width:  16
 Scan time:  4.850

The best scores are:                                      opt bits E(85289)
NP_002023 (OMIM: 134770,615517) ferritin heavy cha ( 183) 1222 276.6 1.6e-74
NP_803431 (OMIM: 608847) ferritin, mitochondrial p ( 242)  981 223.8 1.6e-58
NP_114100 (OMIM: 300308) ferritin heavy polypeptid ( 183)  800 184.1 1.1e-46
NP_000137 (OMIM: 134790,600886,606159,615604) ferr ( 175)  696 161.4 7.3e-40


>>NP_002023 (OMIM: 134770,615517) ferritin heavy chain [  (183 aa)
 initn: 1222 init1: 1222 opt: 1222  Z-score: 1459.1  bits: 276.6 E(85289): 1.6e-74
Smith-Waterman score: 1222; 100.0% identity (100.0% similar) in 183 aa overlap (1-183:1-183)

               10        20        30        40        50        60
pF1KB6 MTTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MTTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 HEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 HEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 LATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDSD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDSD
              130       140       150       160       170       180

          
pF1KB6 NES
       :::
NP_002 NES
          

>>NP_803431 (OMIM: 608847) ferritin, mitochondrial precu  (242 aa)
 initn: 986 init1: 971 opt: 981  Z-score: 1171.8  bits: 223.8 E(85289): 1.6e-58
Smith-Waterman score: 981; 80.6% identity (93.9% similar) in 180 aa overlap (4-183:63-242)

                                          10        20        30   
pF1KB6                            MTTASTSQVRQNYHQDSEAAINRQINLELYASY
                                     :. :.::::.: ::::::::::::::::::
NP_803 APGRPLDPRQIAPRRPLAAAASSRDPTGPAAGPSRVRQNFHPDSEAAINRQINLELYASY
             40        50        60        70        80        90  

            40        50        60        70        80        90   
pF1KB6 VYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDD
       :::::.:::.::::::.::..::::::.:: :::::::.::::::::: :::::::. ::
NP_803 VYLSMAYYFSRDDVALNNFSRYFLHQSREETEHAEKLMRLQNQRGGRIRLQDIKKPEQDD
            100       110       120       130       140       150  

           100       110       120       130       140       150   
pF1KB6 WESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHV
       :::::.:::::: ::::::::::::: ::.::.:::::::.::.:::::::.::::::::
NP_803 WESGLHAMECALLLEKNVNQSLLELHALASDKGDPHLCDFLETYYLNEQVKSIKELGDHV
            160       170       180       190       200       210  

           160       170       180   
pF1KB6 TNLRKMGAPESGLAEYLFDKHTLGDSDNES
        :: :::::..:::::::: ::::. ....
NP_803 HNLVKMGAPDAGLAEYLFDTHTLGNENKQN
            220       230       240  

>>NP_114100 (OMIM: 300308) ferritin heavy polypeptide-li  (183 aa)
 initn: 798 init1: 798 opt: 800  Z-score: 959.5  bits: 184.1 E(85289): 1.1e-46
Smith-Waterman score: 800; 65.0% identity (88.5% similar) in 183 aa overlap (1-183:1-183)

               10        20        30        40        50        60
pF1KB6 MTTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQS
       :.::. :::::.:  . .:::: .:.::::.::.::::..::.::::::.:: .:::. :
NP_114 MATAQPSQVRQKYDTNCDAAINSHITLELYTSYLYLSMAFYFNRDDVALENFFRYFLRLS
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 HEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHK
        .. :::.:::.::: :::.: :.::.::.:. ::::: ::: :.:::::::::::.:..
NP_114 DDKMEHAQKLMRLQNLRGGHICLHDIRKPECQGWESGLVAMESAFHLEKNVNQSLLDLYQ
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 LATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDSD
       ::..:.::.:: :.:.:::.::::.::::: .:.::::. .::.::::::::: :::   
NP_114 LAVEKGDPQLCHFLESHYLHEQVKTIKELGGYVSNLRKICSPEAGLAEYLFDKLTLGGRV
              130       140       150       160       170       180

          
pF1KB6 NES
       .:.
NP_114 KET
          

>>NP_000137 (OMIM: 134790,600886,606159,615604) ferritin  (175 aa)
 initn: 696 init1: 696 opt: 696  Z-score: 836.6  bits: 161.4 E(85289): 7.3e-40
Smith-Waterman score: 696; 56.7% identity (86.0% similar) in 171 aa overlap (6-176:2-172)

               10        20        30        40        50        60
pF1KB6 MTTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQS
            .::.::::  : :::.:  .:: : :::.:::...:::::::::.. ...: . .
NP_000     MSSQIRQNYSTDVEAAVNSLVNLYLQASYTYLSLGFYFDRDDVALEGVSHFFRELA
                   10        20        30        40        50      

               70        80        90       100       110       120
pF1KB6 HEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHK
       .:.::  :.:.:.::::::: ..::::::  :.: .  .::. :. :::..::.::.:: 
NP_000 EEKREGYERLLKMQNQRGGRALFQDIKKPAEDEWGKTPDAMKAAMALEKKLNQALLDLHA
         60        70        80        90       100       110      

              130       140       150       160       170       180
pF1KB6 LATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDSD
       :.. ..:::::::.:::.:.:.:: ::..:::.:::...:.::.::.::::.. ::    
NP_000 LGSARTDPHLCDFLETHFLDEEVKLIKKMGDHLTNLHRLGGPEAGLGEYLFERLTLKHD 
        120       130       140       150       160       170      

          
pF1KB6 NES




183 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 00:25:27 2016 done: Sat Nov  5 00:25:27 2016
 Total Scan time:  4.850 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]