FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6901, 203 aa 1>>>pF1KB6901 203 - 203 aa - 203 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.8371+/-0.000261; mu= 8.1759+/- 0.016 mean_var=118.6917+/-24.062, 0's: 0 Z-trim(122.7): 3 B-trim: 0 in 0/55 Lambda= 0.117724 statistics sampled from 41130 (41133) to 41130 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.807), E-opt: 0.2 (0.482), width: 16 Scan time: 6.810 The best scores are: opt bits E(85289) NP_060534 (OMIM: 615165) akirin-2 [Homo sapiens] ( 203) 1329 235.4 4.9e-62 NP_078871 (OMIM: 615164) akirin-1 isoform 1 [Homo ( 192) 566 105.8 4.8e-23 NP_001129747 (OMIM: 615164) akirin-1 isoform 2 [Ho ( 147) 172 38.8 0.0054 >>NP_060534 (OMIM: 615165) akirin-2 [Homo sapiens] (203 aa) initn: 1329 init1: 1329 opt: 1329 Z-score: 1234.7 bits: 235.4 E(85289): 4.9e-62 Smith-Waterman score: 1329; 100.0% identity (100.0% similar) in 203 aa overlap (1-203:1-203) 10 20 30 40 50 60 pF1KB6 MACGATLKRTLDFDPLLSPASPKRRRCAPLSAPTSAAASPLSAAAATAASFSAAAASPQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MACGATLKRTLDFDPLLSPASPKRRRCAPLSAPTSAAASPLSAAAATAASFSAAAASPQK 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 YLRMEPSPFGDVSSRLTTEQILYNIKQEYKRMQKRRHLETSFQQTDPCCTSDAQPHAFLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 YLRMEPSPFGDVSSRLTTEQILYNIKQEYKRMQKRRHLETSFQQTDPCCTSDAQPHAFLL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 SGPASPGTSSAASSPLKKEQPLFTLRQVGMICERLLKEREEKVREEYEEILNTKLAEQYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 SGPASPGTSSAASSPLKKEQPLFTLRQVGMICERLLKEREEKVREEYEEILNTKLAEQYD 130 140 150 160 170 180 190 200 pF1KB6 AFVKFTHDQIMRRYGEQPASYVS ::::::::::::::::::::::: NP_060 AFVKFTHDQIMRRYGEQPASYVS 190 200 >>NP_078871 (OMIM: 615164) akirin-1 isoform 1 [Homo sapi (192 aa) initn: 602 init1: 390 opt: 566 Z-score: 534.7 bits: 105.8 E(85289): 4.8e-23 Smith-Waterman score: 721; 57.4% identity (77.5% similar) in 204 aa overlap (1-203:1-192) 10 20 30 40 50 pF1KB6 MACGATLKRTLDFDP-LLSPASPKRRRCAPLSAPTSAAASPLSAAAATAASFSAAAASPQ ::::::::: ..:. ::::.:::::::::: .:: . : : :.. .: NP_078 MACGATLKRPMEFEAALLSPGSPKRRRCAPLPGPTPGLRPP---DAEPPPPFQTQ--TPP 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 KYLRMEPSPFGDVSSRLTTEQILYNIKQEYKRMQKRRHLETSFQQTDPCCTSDAQPHAFL . :. .:.: :. : :::. ::::::.:.:. ::::. ..:.. : .:..:::. NP_078 QSLQ-QPAPPGSERRLPTPEQIFQNIKQEYSRYQRWRHLEVVLNQSEAC-ASESQPHSSA 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 LSGPASPGTSSAASSPLKKEQPLFTLRQVGMICERLLKEREEKVREEYEEILNTKLAEQY :..:.::: :: .::.:: :::::::.:::::::. :.:.:::::.:::::::::: NP_078 LTAPSSPG-----SSWMKKDQPTFTLRQVGIICERLLKDYEDKIREEYEQILNTKLAEQY 120 130 140 150 160 180 190 200 pF1KB6 DAFVKFTHDQIMRRYGEQPASYVS ..:::::::::::::: .:.:::: NP_078 ESFVKFTHDQIMRRYGTRPTSYVS 170 180 190 >>NP_001129747 (OMIM: 615164) akirin-1 isoform 2 [Homo s (147 aa) initn: 364 init1: 156 opt: 172 Z-score: 174.7 bits: 38.8 E(85289): 0.0054 Smith-Waterman score: 398; 40.2% identity (56.9% similar) in 204 aa overlap (1-203:1-147) 10 20 30 40 50 pF1KB6 MACGATLKRTLDFDP-LLSPASPKRRRCAPLSAPTSAAASPLSAAAATAASFSAAAASPQ ::::::::: ..:. ::::.:::::::::: .:: . : : :.. .: NP_001 MACGATLKRPMEFEAALLSPGSPKRRRCAPLPGPTPGLRPP---DAEPPPPFQTQ--TPP 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 KYLRMEPSPFGDVSSRLTTEQILYNIKQEYKRMQKRRHLETSFQQTDPCCTSDAQPHAFL . :. .:.: :. : :::. ::::::.:.:. ::::. ..:.. : .:..:::. NP_001 QSLQ-QPAPPGSERRLPTPEQIFQNIKQEYSRYQRWRHLEVVLNQSEAC-ASESQPHSSA 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 LSGPASPGTSSAASSPLKKEQPLFTLRQVGMICERLLKEREEKVREEYEEILNTKLAEQY :..:.:: ::: NP_001 LTAPSSP--------------------------------------------------EQY 120 180 190 200 pF1KB6 DAFVKFTHDQIMRRYGEQPASYVS ..:::::::::::::: .:.:::: NP_001 ESFVKFTHDQIMRRYGTRPTSYVS 130 140 203 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 13:28:51 2016 done: Fri Nov 4 13:28:52 2016 Total Scan time: 6.810 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]