FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6905, 204 aa
1>>>pF1KB6905 204 - 204 aa - 204 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7100+/-0.000324; mu= 17.9341+/- 0.021
mean_var=85.8657+/-16.876, 0's: 0 Z-trim(118.2): 413 B-trim: 626 in 1/51
Lambda= 0.138409
statistics sampled from 30486 (30962) to 30486 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.745), E-opt: 0.2 (0.363), width: 16
Scan time: 5.400
The best scores are: opt bits E(85289)
NP_036382 (OMIM: 600098) ras-related protein R-Ras ( 204) 1366 281.8 5.2e-76
XP_016872852 (OMIM: 600098) PREDICTED: ras-related ( 182) 1136 235.8 3.2e-62
NP_001170785 (OMIM: 600098) ras-related protein R- ( 169) 1128 234.2 9.3e-62
NP_006261 (OMIM: 165090) ras-related protein R-Ras ( 218) 880 184.8 8.8e-47
NP_001170786 (OMIM: 600098) ras-related protein R- ( 127) 856 179.7 1.7e-45
NP_001096139 (OMIM: 600098) ras-related protein R- ( 127) 856 179.7 1.7e-45
XP_005247285 (OMIM: 608435) PREDICTED: ras-related ( 208) 729 154.6 1e-37
NP_001078518 (OMIM: 608435) ras-related protein M- ( 208) 729 154.6 1e-37
XP_016861376 (OMIM: 608435) PREDICTED: ras-related ( 208) 729 154.6 1e-37
NP_001239019 (OMIM: 608435) ras-related protein M- ( 208) 729 154.6 1e-37
NP_036351 (OMIM: 608435) ras-related protein M-Ras ( 208) 729 154.6 1e-37
XP_011518955 (OMIM: 109800,114480,137215,163200,19 ( 188) 677 144.2 1.3e-34
NP_004976 (OMIM: 109800,114480,137215,163200,19007 ( 188) 677 144.2 1.3e-34
NP_001123914 (OMIM: 109800,137550,162900,163200,18 ( 189) 672 143.2 2.6e-34
NP_005334 (OMIM: 109800,137550,162900,163200,18847 ( 189) 672 143.2 2.6e-34
XP_006719132 (OMIM: 109800,114480,137215,163200,19 ( 189) 653 139.4 3.5e-33
NP_203524 (OMIM: 109800,114480,137215,163200,19007 ( 189) 653 139.4 3.5e-33
XP_016874782 (OMIM: 109800,114480,137215,163200,19 ( 227) 653 139.5 4e-33
NP_002515 (OMIM: 114500,137550,162900,163200,16479 ( 189) 639 136.6 2.5e-32
NP_008843 (OMIM: 609591,615355) GTP-binding protei ( 219) 631 135.1 8.2e-32
NP_001243750 (OMIM: 609591,615355) GTP-binding pro ( 236) 631 135.1 8.6e-32
NP_002921 (OMIM: 609592) GTP-binding protein Rit2 ( 217) 619 132.7 4.3e-31
XP_005247286 (OMIM: 608435) PREDICTED: ras-related ( 170) 614 131.6 7.3e-31
NP_001010942 (OMIM: 179530) ras-related protein Ra ( 184) 614 131.6 7.7e-31
NP_056461 (OMIM: 179530) ras-related protein Rap-1 ( 184) 614 131.6 7.7e-31
NP_001010935 (OMIM: 179520) ras-related protein Ra ( 184) 607 130.2 2e-30
NP_001278825 (OMIM: 179520) ras-related protein Ra ( 184) 607 130.2 2e-30
XP_016857451 (OMIM: 179520) PREDICTED: ras-related ( 184) 607 130.2 2e-30
XP_016857452 (OMIM: 179520) PREDICTED: ras-related ( 184) 607 130.2 2e-30
XP_016857453 (OMIM: 179520) PREDICTED: ras-related ( 184) 607 130.2 2e-30
NP_002875 (OMIM: 179520) ras-related protein Rap-1 ( 184) 607 130.2 2e-30
NP_789765 (OMIM: 109800,137550,162900,163200,18847 ( 170) 601 129.0 4.4e-30
NP_002872 (OMIM: 179551) ras-related protein Ral-B ( 206) 593 127.5 1.5e-29
XP_005263784 (OMIM: 179551) PREDICTED: ras-related ( 206) 593 127.5 1.5e-29
XP_016860111 (OMIM: 179551) PREDICTED: ras-related ( 206) 593 127.5 1.5e-29
XP_005263785 (OMIM: 179551) PREDICTED: ras-related ( 206) 593 127.5 1.5e-29
XP_005263786 (OMIM: 179551) PREDICTED: ras-related ( 206) 593 127.5 1.5e-29
XP_016860110 (OMIM: 179551) PREDICTED: ras-related ( 228) 593 127.5 1.6e-29
XP_005263781 (OMIM: 179551) PREDICTED: ras-related ( 228) 593 127.5 1.6e-29
XP_011509875 (OMIM: 179551) PREDICTED: ras-related ( 229) 593 127.5 1.6e-29
XP_006715825 (OMIM: 179550) PREDICTED: ras-related ( 206) 588 126.5 3e-29
XP_011513768 (OMIM: 179550) PREDICTED: ras-related ( 206) 588 126.5 3e-29
NP_005393 (OMIM: 179550) ras-related protein Ral-A ( 206) 588 126.5 3e-29
XP_016857450 (OMIM: 179520) PREDICTED: ras-related ( 195) 566 122.1 6.1e-28
XP_016857449 (OMIM: 179520) PREDICTED: ras-related ( 195) 566 122.1 6.1e-28
NP_001243749 (OMIM: 609591,615355) GTP-binding pro ( 183) 554 119.6 3.1e-27
NP_002877 (OMIM: 179541) ras-related protein Rap-2 ( 183) 539 116.6 2.5e-26
NP_066361 (OMIM: 179540) ras-related protein Rap-2 ( 183) 534 115.6 4.9e-26
NP_116307 (OMIM: 612664) ras-related and estrogen- ( 199) 506 110.1 2.5e-24
NP_001259006 (OMIM: 609592) GTP-binding protein Ri ( 153) 493 107.4 1.3e-23
>>NP_036382 (OMIM: 600098) ras-related protein R-Ras2 is (204 aa)
initn: 1366 init1: 1366 opt: 1366 Z-score: 1485.7 bits: 281.8 E(85289): 5.2e-76
Smith-Waterman score: 1366; 100.0% identity (100.0% similar) in 204 aa overlap (1-204:1-204)
10 20 30 40 50 60
pF1KB6 MAAAGWRDGSGQEKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MAAAGWRDGSGQEKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 AARLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 AARLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 PMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAKIRMNVDQAFHELVRVIRKFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAKIRMNVDQAFHELVRVIRKFQE
130 140 150 160 170 180
190 200
pF1KB6 QECPPSPEPTRKEKDKKGCHCVIF
::::::::::::::::::::::::
NP_036 QECPPSPEPTRKEKDKKGCHCVIF
190 200
>>XP_016872852 (OMIM: 600098) PREDICTED: ras-related pro (182 aa)
initn: 1134 init1: 1134 opt: 1136 Z-score: 1238.0 bits: 235.8 E(85289): 3.2e-62
Smith-Waterman score: 1136; 95.0% identity (96.7% similar) in 181 aa overlap (24-204:5-182)
10 20 30 40 50 60
pF1KB6 MAAAGWRDGSGQEKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDR
: :.. : :.::::::::::::::::::::::::
XP_016 MTKLGSGEARL---HIRSYFVTDYDPTIEDSYTKQCVIDDR
10 20 30
70 80 90 100 110 120
pF1KB6 AARLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AARLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEF
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB6 PMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAKIRMNVDQAFHELVRVIRKFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAKIRMNVDQAFHELVRVIRKFQE
100 110 120 130 140 150
190 200
pF1KB6 QECPPSPEPTRKEKDKKGCHCVIF
::::::::::::::::::::::::
XP_016 QECPPSPEPTRKEKDKKGCHCVIF
160 170 180
>>NP_001170785 (OMIM: 600098) ras-related protein R-Ras2 (169 aa)
initn: 1128 init1: 1128 opt: 1128 Z-score: 1229.8 bits: 234.2 E(85289): 9.3e-62
Smith-Waterman score: 1128; 100.0% identity (100.0% similar) in 168 aa overlap (37-204:2-169)
10 20 30 40 50 60
pF1KB6 RDGSGQEKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDRAARLDI
::::::::::::::::::::::::::::::
NP_001 MSYFVTDYDPTIEDSYTKQCVIDDRAARLDI
10 20 30
70 80 90 100 110 120
pF1KB6 LDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIG
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB6 NKADLDHQRQVTQEEGQQLARQLKVTYMEASAKIRMNVDQAFHELVRVIRKFQEQECPPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKADLDHQRQVTQEEGQQLARQLKVTYMEASAKIRMNVDQAFHELVRVIRKFQEQECPPS
100 110 120 130 140 150
190 200
pF1KB6 PEPTRKEKDKKGCHCVIF
::::::::::::::::::
NP_001 PEPTRKEKDKKGCHCVIF
160
>>NP_006261 (OMIM: 165090) ras-related protein R-Ras [Ho (218 aa)
initn: 864 init1: 838 opt: 880 Z-score: 960.8 bits: 184.8 E(85289): 8.8e-47
Smith-Waterman score: 880; 66.0% identity (85.5% similar) in 200 aa overlap (5-204:20-218)
10 20 30 40
pF1KB6 MAAAGWRDGSGQEKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDP
: : .: ..::::::::::::::::::::::::.::::
NP_006 MSSGAASGTGRGRPRGGGPGPGDPPPSETHKLVVVGGGGVGKSALTIQFIQSYFVSDYDP
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB6 TIEDSYTKQCVIDDRAARLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIY
:::::::: : .: :::::::::::::::::::::::.:.::::::...:: ::.:.
NP_006 TIEDSYTKICSVDGIPARLDILDTAGQEEFGAMREQYMRAGHGFLLVFAINDRQSFNEVG
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB6 KFQRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAKIRMNVD
:. :::::::::.::..:.::::::. :::: . :.. .. . .:.:.:::::.:.:::
NP_006 KLFTQILRVKDRDDFPVVLVGNKADLESQRQVPRSEASAFGASHHVAYFEASAKLRLNVD
130 140 150 160 170 180
170 180 190 200
pF1KB6 QAFHELVRVIRKFQEQECPPSPEPTRKEKDKKGCHCVIF
.::..:::..::.:::: :::: :. .: :: ::..
NP_006 EAFEQLVRAVRKYQEQELPPSP-PSAPRKKGGGCPCVLL
190 200 210
>>NP_001170786 (OMIM: 600098) ras-related protein R-Ras2 (127 aa)
initn: 856 init1: 856 opt: 856 Z-score: 937.7 bits: 179.7 E(85289): 1.7e-45
Smith-Waterman score: 856; 100.0% identity (100.0% similar) in 127 aa overlap (78-204:1-127)
50 60 70 80 90 100
pF1KB6 EDSYTKQCVIDDRAARLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKF
::::::::::::::::::::::::::::::
NP_001 MREQYMRTGEGFLLVFSVTDRGSFEEIYKF
10 20 30
110 120 130 140 150 160
pF1KB6 QRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAKIRMNVDQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAKIRMNVDQA
40 50 60 70 80 90
170 180 190 200
pF1KB6 FHELVRVIRKFQEQECPPSPEPTRKEKDKKGCHCVIF
:::::::::::::::::::::::::::::::::::::
NP_001 FHELVRVIRKFQEQECPPSPEPTRKEKDKKGCHCVIF
100 110 120
>>NP_001096139 (OMIM: 600098) ras-related protein R-Ras2 (127 aa)
initn: 856 init1: 856 opt: 856 Z-score: 937.7 bits: 179.7 E(85289): 1.7e-45
Smith-Waterman score: 856; 100.0% identity (100.0% similar) in 127 aa overlap (78-204:1-127)
50 60 70 80 90 100
pF1KB6 EDSYTKQCVIDDRAARLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKF
::::::::::::::::::::::::::::::
NP_001 MREQYMRTGEGFLLVFSVTDRGSFEEIYKF
10 20 30
110 120 130 140 150 160
pF1KB6 QRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAKIRMNVDQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRQILRVKDRDEFPMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAKIRMNVDQA
40 50 60 70 80 90
170 180 190 200
pF1KB6 FHELVRVIRKFQEQECPPSPEPTRKEKDKKGCHCVIF
:::::::::::::::::::::::::::::::::::::
NP_001 FHELVRVIRKFQEQECPPSPEPTRKEKDKKGCHCVIF
100 110 120
>>XP_005247285 (OMIM: 608435) PREDICTED: ras-related pro (208 aa)
initn: 713 init1: 644 opt: 729 Z-score: 798.1 bits: 154.6 E(85289): 1e-37
Smith-Waterman score: 729; 58.5% identity (82.1% similar) in 195 aa overlap (15-204:14-208)
10 20 30 40 50 60
pF1KB6 MAAAGWRDGSGQEKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDR
:.::::: ::::::::::::.:. :: :::::::::: :. ::..
XP_005 MATSAVPSDNLPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQ
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 AARLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEF
: ::.:::::::::.::::::::::.:::.:.::::..:::.. .:.. :::::::. :
XP_005 WAILDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESF
60 70 80 90 100 110
130 140 150 160 170
pF1KB6 PMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAK-IRMNVDQAFHELVRVIRKFQ
::::..::.:: : :..:.:.:...: . .. :.:.::: .:::.:::.::::::.
XP_005 PMILVANKVDLMHLRKITREQGKEMATKHNIPYIETSAKDPPLNVDKAFHDLVRVIRQQI
120 130 140 150 160 170
180 190 200
pF1KB6 EQECPPSPEPTRKEKDKK-GCH---CVIF
.. . . :. . :. : : :::.
XP_005 PEKSQKKKKKTKWRGDRATGTHKLQCVIL
180 190 200
>>NP_001078518 (OMIM: 608435) ras-related protein M-Ras (208 aa)
initn: 713 init1: 644 opt: 729 Z-score: 798.1 bits: 154.6 E(85289): 1e-37
Smith-Waterman score: 729; 58.5% identity (82.1% similar) in 195 aa overlap (15-204:14-208)
10 20 30 40 50 60
pF1KB6 MAAAGWRDGSGQEKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDR
:.::::: ::::::::::::.:. :: :::::::::: :. ::..
NP_001 MATSAVPSDNLPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQ
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 AARLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEF
: ::.:::::::::.::::::::::.:::.:.::::..:::.. .:.. :::::::. :
NP_001 WAILDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESF
60 70 80 90 100 110
130 140 150 160 170
pF1KB6 PMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAK-IRMNVDQAFHELVRVIRKFQ
::::..::.:: : :..:.:.:...: . .. :.:.::: .:::.:::.::::::.
NP_001 PMILVANKVDLMHLRKITREQGKEMATKHNIPYIETSAKDPPLNVDKAFHDLVRVIRQQI
120 130 140 150 160 170
180 190 200
pF1KB6 EQECPPSPEPTRKEKDKK-GCH---CVIF
.. . . :. . :. : : :::.
NP_001 PEKSQKKKKKTKWRGDRATGTHKLQCVIL
180 190 200
>>XP_016861376 (OMIM: 608435) PREDICTED: ras-related pro (208 aa)
initn: 713 init1: 644 opt: 729 Z-score: 798.1 bits: 154.6 E(85289): 1e-37
Smith-Waterman score: 729; 58.5% identity (82.1% similar) in 195 aa overlap (15-204:14-208)
10 20 30 40 50 60
pF1KB6 MAAAGWRDGSGQEKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDR
:.::::: ::::::::::::.:. :: :::::::::: :. ::..
XP_016 MATSAVPSDNLPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQ
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 AARLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEF
: ::.:::::::::.::::::::::.:::.:.::::..:::.. .:.. :::::::. :
XP_016 WAILDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESF
60 70 80 90 100 110
130 140 150 160 170
pF1KB6 PMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAK-IRMNVDQAFHELVRVIRKFQ
::::..::.:: : :..:.:.:...: . .. :.:.::: .:::.:::.::::::.
XP_016 PMILVANKVDLMHLRKITREQGKEMATKHNIPYIETSAKDPPLNVDKAFHDLVRVIRQQI
120 130 140 150 160 170
180 190 200
pF1KB6 EQECPPSPEPTRKEKDKK-GCH---CVIF
.. . . :. . :. : : :::.
XP_016 PEKSQKKKKKTKWRGDRATGTHKLQCVIL
180 190 200
>>NP_001239019 (OMIM: 608435) ras-related protein M-Ras (208 aa)
initn: 713 init1: 644 opt: 729 Z-score: 798.1 bits: 154.6 E(85289): 1e-37
Smith-Waterman score: 729; 58.5% identity (82.1% similar) in 195 aa overlap (15-204:14-208)
10 20 30 40 50 60
pF1KB6 MAAAGWRDGSGQEKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDR
:.::::: ::::::::::::.:. :: :::::::::: :. ::..
NP_001 MATSAVPSDNLPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQ
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 AARLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEF
: ::.:::::::::.::::::::::.:::.:.::::..:::.. .:.. :::::::. :
NP_001 WAILDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESF
60 70 80 90 100 110
130 140 150 160 170
pF1KB6 PMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAK-IRMNVDQAFHELVRVIRKFQ
::::..::.:: : :..:.:.:...: . .. :.:.::: .:::.:::.::::::.
NP_001 PMILVANKVDLMHLRKITREQGKEMATKHNIPYIETSAKDPPLNVDKAFHDLVRVIRQQI
120 130 140 150 160 170
180 190 200
pF1KB6 EQECPPSPEPTRKEKDKK-GCH---CVIF
.. . . :. . :. : : :::.
NP_001 PEKSQKKKKKTKWRGDRATGTHKLQCVIL
180 190 200
204 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 13:12:30 2016 done: Fri Nov 4 13:12:31 2016
Total Scan time: 5.400 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]