FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6908, 224 aa 1>>>pF1KB6908 224 - 224 aa - 224 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7110+/-0.000791; mu= 12.4092+/- 0.047 mean_var=75.1812+/-14.776, 0's: 0 Z-trim(108.0): 31 B-trim: 0 in 0/52 Lambda= 0.147918 statistics sampled from 9869 (9900) to 9869 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.696), E-opt: 0.2 (0.304), width: 16 Scan time: 1.880 The best scores are: opt bits E(32554) CCDS9683.1 FKBP3 gene_id:2287|Hs108|chr14 ( 224) 1469 322.4 1.4e-88 CCDS8063.1 FKBP2 gene_id:2286|Hs108|chr11 ( 142) 305 73.9 5.9e-14 CCDS13014.1 FKBP1A gene_id:2280|Hs108|chr20 ( 108) 291 70.9 3.7e-13 CCDS8512.1 FKBP4 gene_id:2288|Hs108|chr12 ( 459) 287 70.3 2.3e-12 CCDS1706.1 FKBP1B gene_id:2281|Hs108|chr2 ( 108) 277 67.9 2.9e-12 CCDS54996.1 FKBP5 gene_id:2289|Hs108|chr6 ( 268) 266 65.7 3.2e-11 CCDS4808.1 FKBP5 gene_id:2289|Hs108|chr6 ( 457) 266 65.8 5e-11 >>CCDS9683.1 FKBP3 gene_id:2287|Hs108|chr14 (224 aa) initn: 1469 init1: 1469 opt: 1469 Z-score: 1703.5 bits: 322.4 E(32554): 1.4e-88 Smith-Waterman score: 1469; 100.0% identity (100.0% similar) in 224 aa overlap (1-224:1-224) 10 20 30 40 50 60 pF1KB6 MAAAVPQRAWTVEQLRSEQLPKKDIIKFLQEHGSDSFLAEHKLLGNIKNVAKTANKDHLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 MAAAVPQRAWTVEQLRSEQLPKKDIIKFLQEHGSDSFLAEHKLLGNIKNVAKTANKDHLV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 TAYNHLFETKRFKGTESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 TAYNHLFETKRFKGTESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 KTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS96 KTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALL 130 140 150 160 170 180 190 200 210 220 pF1KB6 TMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID :::::::::::::::::::::::::::::::::::::::::::: CCDS96 TMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID 190 200 210 220 >>CCDS8063.1 FKBP2 gene_id:2286|Hs108|chr11 (142 aa) initn: 264 init1: 128 opt: 305 Z-score: 364.1 bits: 73.9 E(32554): 5.9e-14 Smith-Waterman score: 305; 44.2% identity (68.3% similar) in 120 aa overlap (106-224:26-137) 80 90 100 110 120 130 pF1KB6 ESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFP-KKGDVVHCW :: : .: :. :. . .::::.: CCDS80 MRLSWFRVLTVLSICLSAVATATGAEGKRKLQIGVKKRVDHCPIKSRKGDVLHMH 10 20 30 40 50 140 150 160 170 180 190 pF1KB6 YTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEP ::: :.::: ::... . .:. :..:.:.::.:::..:: : .::: .: : CCDS80 YTGKLEDGTEFDSSLPQN-------QPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPS 60 70 80 90 100 200 210 220 pF1KB6 EWAYGKKGQPDAKIPPNAKLTFEVELVDID : .::..: : ::: .: :.:::::. :. CCDS80 ELGYGERGAPP-KIPGGATLVFEVELLKIERRTEL 110 120 130 140 >>CCDS13014.1 FKBP1A gene_id:2280|Hs108|chr20 (108 aa) initn: 298 init1: 164 opt: 291 Z-score: 349.7 bits: 70.9 E(32554): 3.7e-13 Smith-Waterman score: 292; 44.1% identity (70.3% similar) in 111 aa overlap (116-224:8-108) 90 100 110 120 130 140 pF1KB6 KNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFPKKGD--VVHCWYTGTLQDGT .. :: .:::.:. ::: ::: :.:: CCDS13 MGVQVETISPGDGRTFPKRGQTCVVH--YTGMLEDGK 10 20 30 150 160 170 180 190 200 pF1KB6 VFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQ ::.. . .: ::..: .: .:::::.:.. :: :..:.: : :..::: :. CCDS13 KFDSS------RDRN-KPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDYAYGATGH 40 50 60 70 80 210 220 pF1KB6 PDAKIPPNAKLTFEVELVDID : :::.: :.:.:::. .. CCDS13 PGI-IPPHATLVFDVELLKLE 90 100 >>CCDS8512.1 FKBP4 gene_id:2288|Hs108|chr12 (459 aa) initn: 296 init1: 139 opt: 287 Z-score: 335.6 bits: 70.3 E(32554): 2.3e-12 Smith-Waterman score: 287; 45.8% identity (66.9% similar) in 118 aa overlap (109-222:27-136) 80 90 100 110 120 130 pF1KB6 SKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLK----KGDKTNFPKKGDVVHCW :: ..::: .: :..: :: : CCDS85 MTAEEMKATESGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVH 10 20 30 40 50 140 150 160 170 180 190 pF1KB6 YTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEP ::: : ::: ::.... .: : .:: .: :.::..:: :. ::. :: .. .: CCDS85 YTGWLLDGTKFDSSLD---RKDK----FSFDLGKGEVIKAWDIAIATMKVGEVCHITCKP 60 70 80 90 100 200 210 220 pF1KB6 EWAYGKKGQPDAKIPPNAKLTFEVELVDID :.:::. :.: :::::: :.::::: . CCDS85 EYAYGSAGSPP-KIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGA 110 120 130 140 150 160 >>CCDS1706.1 FKBP1B gene_id:2281|Hs108|chr2 (108 aa) initn: 297 init1: 139 opt: 277 Z-score: 333.6 bits: 67.9 E(32554): 2.9e-12 Smith-Waterman score: 278; 43.2% identity (69.4% similar) in 111 aa overlap (116-224:8-108) 90 100 110 120 130 140 pF1KB6 KNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFPKKGD--VVHCWYTGTLQDGT .. :: .:::::. ::: ::: ::.: CCDS17 MGVEIETISPGDGRTFPKKGQTCVVH--YTGMLQNGK 10 20 30 150 160 170 180 190 200 pF1KB6 VFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQ ::.. . .: ::..:..: .::.:..:. :: :..:.: :. ::: :. CCDS17 KFDSS------RDRN-KPFKFRIGKQEVIKGFEEGAAQMSLGQRAKLTCTPDVAYGATGH 40 50 60 70 80 210 220 pF1KB6 PDAKIPPNAKLTFEVELVDID : . ::::: : :.:::.... CCDS17 PGV-IPPNATLIFDVELLNLE 90 100 >>CCDS54996.1 FKBP5 gene_id:2289|Hs108|chr6 (268 aa) initn: 210 init1: 106 opt: 266 Z-score: 314.9 bits: 65.7 E(32554): 3.2e-11 Smith-Waterman score: 266; 38.3% identity (62.4% similar) in 141 aa overlap (86-222:5-136) 60 70 80 90 100 110 pF1KB6 KDHLVTAYNHLFETKRFKGTESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPK---YT ...: ::..: : .:. : : CCDS54 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVL 10 20 30 120 130 140 150 160 170 pF1KB6 KSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVI : : . :. . : :: :. : : :..: ::.. . .: .:. :..: :.:: CCDS54 KIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSS------HDRN-EPFVFSLGKGQVI 40 50 60 70 80 180 190 200 210 220 pF1KB6 RGWDEALLTMSKGEKARLEIEPEWAYGKKGQ-PDAKIPPNAKLTFEVELVDID ..:: .. ::.::: .: .::.:::. :. : ::: :: : ::.::.: CCDS54 KAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP--KIPSNATLFFEIELLDFKGEDLFED 90 100 110 120 130 140 CCDS54 GGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTVGEGEDHDIPIGIDKA 150 160 170 180 190 200 >>CCDS4808.1 FKBP5 gene_id:2289|Hs108|chr6 (457 aa) initn: 184 init1: 106 opt: 266 Z-score: 311.4 bits: 65.8 E(32554): 5e-11 Smith-Waterman score: 266; 38.3% identity (62.4% similar) in 141 aa overlap (86-222:5-136) 60 70 80 90 100 110 pF1KB6 KDHLVTAYNHLFETKRFKGTESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPK---YT ...: ::..: : .:. : : CCDS48 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVL 10 20 30 120 130 140 150 160 170 pF1KB6 KSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVI : : . :. . : :: :. : : :..: ::.. . .: .:. :..: :.:: CCDS48 KIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSS------HDRN-EPFVFSLGKGQVI 40 50 60 70 80 180 190 200 210 220 pF1KB6 RGWDEALLTMSKGEKARLEIEPEWAYGKKGQ-PDAKIPPNAKLTFEVELVDID ..:: .. ::.::: .: .::.:::. :. : ::: :: : ::.::.: CCDS48 KAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP--KIPSNATLFFEIELLDFKGEDLFED 90 100 110 120 130 140 CCDS48 GGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTVGEGEDHDIPIGIDKA 150 160 170 180 190 200 224 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 13:03:25 2016 done: Fri Nov 4 13:03:25 2016 Total Scan time: 1.880 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]