FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6913, 205 aa 1>>>pF1KB6913 205 - 205 aa - 205 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5052+/-0.000797; mu= 12.6329+/- 0.048 mean_var=71.1446+/-14.089, 0's: 0 Z-trim(107.5): 48 B-trim: 0 in 0/51 Lambda= 0.152056 statistics sampled from 9568 (9616) to 9568 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.68), E-opt: 0.2 (0.295), width: 16 Scan time: 1.470 The best scores are: opt bits E(32554) CCDS1243.1 RGS4 gene_id:5999|Hs108|chr1 ( 205) 1371 309.5 9.2e-85 CCDS44270.1 RGS4 gene_id:5999|Hs108|chr1 ( 302) 1371 309.6 1.3e-84 CCDS44272.1 RGS4 gene_id:5999|Hs108|chr1 ( 187) 1245 281.8 1.8e-76 CCDS1244.1 RGS5 gene_id:8490|Hs108|chr1 ( 181) 637 148.5 2.5e-36 CCDS58041.1 RGS5 gene_id:8490|Hs108|chr1 ( 185) 619 144.5 3.9e-35 CCDS1349.1 RGS8 gene_id:85397|Hs108|chr1 ( 198) 603 141.0 4.7e-34 CCDS41443.1 RGS8 gene_id:85397|Hs108|chr1 ( 180) 602 140.8 5e-34 CCDS35114.1 RGS3 gene_id:5998|Hs108|chr9 ( 311) 595 139.4 2.3e-33 CCDS6798.1 RGS3 gene_id:5998|Hs108|chr9 ( 519) 590 138.4 7.5e-33 CCDS65111.1 RGS3 gene_id:5998|Hs108|chr9 ( 591) 590 138.4 8.4e-33 CCDS6797.1 RGS3 gene_id:5998|Hs108|chr9 ( 917) 590 138.5 1.2e-32 CCDS43869.1 RGS3 gene_id:5998|Hs108|chr9 (1198) 590 138.6 1.5e-32 CCDS1348.1 RGS16 gene_id:6004|Hs108|chr1 ( 202) 551 129.6 1.3e-30 CCDS1374.1 RGS18 gene_id:64407|Hs108|chr1 ( 235) 517 122.2 2.6e-28 CCDS1377.1 RGS2 gene_id:5997|Hs108|chr1 ( 211) 511 120.9 5.9e-28 CCDS44271.1 RGS4 gene_id:5999|Hs108|chr1 ( 93) 488 115.6 9.7e-27 CCDS41448.1 RGS21 gene_id:431704|Hs108|chr1 ( 152) 477 113.3 7.8e-26 CCDS1375.2 RGS1 gene_id:5996|Hs108|chr1 ( 209) 454 108.3 3.4e-24 CCDS1376.1 RGS13 gene_id:6003|Hs108|chr1 ( 159) 426 102.1 1.9e-22 CCDS13555.1 RGS19 gene_id:10287|Hs108|chr20 ( 217) 404 97.4 7e-21 CCDS6156.1 RGS20 gene_id:8601|Hs108|chr8 ( 241) 399 96.3 1.6e-20 CCDS69482.1 RGS20 gene_id:8601|Hs108|chr8 ( 273) 399 96.3 1.8e-20 CCDS6155.1 RGS20 gene_id:8601|Hs108|chr8 ( 388) 399 96.4 2.4e-20 CCDS5244.1 RGS17 gene_id:26575|Hs108|chr6 ( 210) 383 92.8 1.7e-19 CCDS41572.1 RGS10 gene_id:6001|Hs108|chr10 ( 167) 362 88.1 3.3e-18 CCDS31294.1 RGS10 gene_id:6001|Hs108|chr10 ( 181) 362 88.1 3.6e-18 CCDS3368.1 RGS12 gene_id:6002|Hs108|chr4 ( 799) 326 80.6 2.9e-15 CCDS3367.1 RGS12 gene_id:6002|Hs108|chr4 (1376) 326 80.7 4.6e-15 CCDS3366.1 RGS12 gene_id:6002|Hs108|chr4 (1447) 326 80.7 4.8e-15 CCDS60457.1 RGS7 gene_id:6000|Hs108|chr1 ( 424) 312 77.4 1.5e-14 CCDS60458.1 RGS7 gene_id:6000|Hs108|chr1 ( 469) 312 77.4 1.6e-14 CCDS60459.1 RGS7 gene_id:6000|Hs108|chr1 ( 477) 312 77.4 1.6e-14 CCDS31071.1 RGS7 gene_id:6000|Hs108|chr1 ( 487) 310 77.0 2.2e-14 CCDS55924.1 RGS6 gene_id:9628|Hs108|chr14 ( 490) 308 76.5 3e-14 CCDS73655.1 RGS6 gene_id:9628|Hs108|chr14 ( 437) 302 75.2 6.8e-14 CCDS43405.1 RGS14 gene_id:10636|Hs108|chr5 ( 566) 303 75.5 7.3e-14 CCDS9808.1 RGS6 gene_id:9628|Hs108|chr14 ( 472) 302 75.2 7.3e-14 CCDS45764.1 RGS9 gene_id:8787|Hs108|chr17 ( 671) 301 75.1 1.1e-13 CCDS42373.1 RGS9 gene_id:8787|Hs108|chr17 ( 674) 301 75.1 1.1e-13 CCDS10403.1 RGS11 gene_id:8786|Hs108|chr16 ( 446) 275 69.3 4.2e-12 CCDS66884.1 RGS11 gene_id:8786|Hs108|chr16 ( 456) 275 69.3 4.3e-12 CCDS42088.1 RGS11 gene_id:8786|Hs108|chr16 ( 467) 275 69.3 4.4e-12 CCDS55652.1 RGS5 gene_id:8490|Hs108|chr1 ( 73) 255 64.4 1.9e-11 >>CCDS1243.1 RGS4 gene_id:5999|Hs108|chr1 (205 aa) initn: 1371 init1: 1371 opt: 1371 Z-score: 1635.2 bits: 309.5 E(32554): 9.2e-85 Smith-Waterman score: 1371; 100.0% identity (100.0% similar) in 205 aa overlap (1-205:1-205) 10 20 30 40 50 60 pF1KB6 MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHNSSHNKKDKVVICQRVSQEEVKKWA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHNSSHNKKDKVVICQRVSQEEVKKWA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 ESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFIS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 VQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLVNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 VQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLVNP 130 140 150 160 170 180 190 200 pF1KB6 SSCGAEKQKGAKSSADCASLVPQCA ::::::::::::::::::::::::: CCDS12 SSCGAEKQKGAKSSADCASLVPQCA 190 200 >>CCDS44270.1 RGS4 gene_id:5999|Hs108|chr1 (302 aa) initn: 1371 init1: 1371 opt: 1371 Z-score: 1632.7 bits: 309.6 E(32554): 1.3e-84 Smith-Waterman score: 1371; 100.0% identity (100.0% similar) in 205 aa overlap (1-205:98-302) 10 20 30 pF1KB6 MCKGLAGLPASCLRSAKDMKHRLGFLLQKS :::::::::::::::::::::::::::::: CCDS44 GEEAKYAQSRSHSSSCRISFLLANSKLLNKMCKGLAGLPASCLRSAKDMKHRLGFLLQKS 70 80 90 100 110 120 40 50 60 70 80 90 pF1KB6 DSCEHNSSHNKKDKVVICQRVSQEEVKKWAESLENLISHECGLAAFKAFLKSEYSEENID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 DSCEHNSSHNKKDKVVICQRVSQEEVKKWAESLENLISHECGLAAFKAFLKSEYSEENID 130 140 150 160 170 180 100 110 120 130 140 150 pF1KB6 FWISCEEYKKIKSPSKLSPKAKKIYNEFISVQATKEVNLDSCTREETSRNMLEPTITCFD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 FWISCEEYKKIKSPSKLSPKAKKIYNEFISVQATKEVNLDSCTREETSRNMLEPTITCFD 190 200 210 220 230 240 160 170 180 190 200 pF1KB6 EAQKKIFNLMEKDSYRRFLKSRFYLDLVNPSSCGAEKQKGAKSSADCASLVPQCA ::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 EAQKKIFNLMEKDSYRRFLKSRFYLDLVNPSSCGAEKQKGAKSSADCASLVPQCA 250 260 270 280 290 300 >>CCDS44272.1 RGS4 gene_id:5999|Hs108|chr1 (187 aa) initn: 1245 init1: 1245 opt: 1245 Z-score: 1486.4 bits: 281.8 E(32554): 1.8e-76 Smith-Waterman score: 1245; 100.0% identity (100.0% similar) in 187 aa overlap (19-205:1-187) 10 20 30 40 50 60 pF1KB6 MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHNSSHNKKDKVVICQRVSQEEVKKWA :::::::::::::::::::::::::::::::::::::::::: CCDS44 MKHRLGFLLQKSDSCEHNSSHNKKDKVVICQRVSQEEVKKWA 10 20 30 40 70 80 90 100 110 120 pF1KB6 ESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 ESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFIS 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB6 VQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLVNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 VQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLVNP 110 120 130 140 150 160 190 200 pF1KB6 SSCGAEKQKGAKSSADCASLVPQCA ::::::::::::::::::::::::: CCDS44 SSCGAEKQKGAKSSADCASLVPQCA 170 180 >>CCDS1244.1 RGS5 gene_id:8490|Hs108|chr1 (181 aa) initn: 622 init1: 471 opt: 637 Z-score: 765.8 bits: 148.5 E(32554): 2.5e-36 Smith-Waterman score: 637; 53.3% identity (82.8% similar) in 180 aa overlap (1-178:1-180) 10 20 30 40 50 pF1KB6 MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSC-EHNSSHNKK-DKVVICQRVSQEEVKK ::::::.:: :::. ::..: .::.:::: :: . .:.: .: . :..: .:. . CCDS12 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQ 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 WAESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEF : .::..:.... :::.::.:::::.::::..:::.::.:::::::.:.. :::.::.:: CCDS12 WRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 ISVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLV :...: ::::.: :.. : .:..::... :: :::.: :::::: ::..:.:: .:. CCDS12 IQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELI 130 140 150 160 170 180 180 190 200 pF1KB6 NPSSCGAEKQKGAKSSADCASLVPQCA CCDS12 K >>CCDS58041.1 RGS5 gene_id:8490|Hs108|chr1 (185 aa) initn: 600 init1: 298 opt: 619 Z-score: 744.3 bits: 144.5 E(32554): 3.9e-35 Smith-Waterman score: 619; 52.2% identity (81.0% similar) in 184 aa overlap (1-178:1-184) 10 20 30 40 50 pF1KB6 MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSC-EHNSSHNKK-DKVVICQRVSQEEVKK ::::::.:: :::. ::..: .::.:::: :: . .:.: .: . :..: .:. . CCDS58 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQ 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 WAESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEF : .::..:.... :::.::.:::::.::::..:::.::.:::::::.:.. :::.::.:: CCDS58 WRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEF 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 ISVQATKEV----NLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFY :...: ::: :.: :.. : .:..::... :: :::.: :::::: ::..:.:: CCDS58 IQTEAPKEVGLWVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFY 130 140 150 160 170 180 180 190 200 pF1KB6 LDLVNPSSCGAEKQKGAKSSADCASLVPQCA .:. CCDS58 QELIK >>CCDS1349.1 RGS8 gene_id:85397|Hs108|chr1 (198 aa) initn: 612 init1: 580 opt: 603 Z-score: 724.9 bits: 141.0 E(32554): 4.7e-34 Smith-Waterman score: 603; 51.8% identity (81.2% similar) in 170 aa overlap (14-181:26-193) 10 20 30 40 pF1KB6 MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHNSS--HNKKDKVV :. : :. ::: : .::::: .. .: .... CCDS13 MWNTLTRSLSDHPVGKDPQAMRTGQRQNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRAL 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB6 ICQRVSQEEVKKWAESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSK .:.: ::. .::.:.. :.::. :.:::.::::.:.::::..::..:::.:: .: .: CCDS13 --KRLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAK 70 80 90 100 110 110 120 130 140 150 160 pF1KB6 LSPKAKKIYNEFISVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYR : ::..:..::..::: .:::.: ::: : .:. ::..::::.:: :. .::::::: CCDS13 LVSKAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYP 120 130 140 150 160 170 170 180 190 200 pF1KB6 RFLKSRFYLDLVNPSSCGAEKQKGAKSSADCASLVPQCA :::.:..::::.. : CCDS13 RFLRSKMYLDLLSQSQRRLS 180 190 >>CCDS41443.1 RGS8 gene_id:85397|Hs108|chr1 (180 aa) initn: 612 init1: 580 opt: 602 Z-score: 724.4 bits: 140.8 E(32554): 5e-34 Smith-Waterman score: 602; 51.8% identity (80.6% similar) in 170 aa overlap (14-181:8-175) 10 20 30 40 50 pF1KB6 MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHNSS--HNKKDKVVICQRVSQEEVKK : : :. ::: : .::::: .. .: .... .:.: ::. . CCDS41 MAALLMPRRNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRAL--KRLSTEEATR 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 WAESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEF ::.:.. :.::. :.:::.::::.:.::::..::..:::.:: .: .:: ::..:..:: CCDS41 WADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEF 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 ISVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLV ..::: .:::.: ::: : .:. ::..::::.:: :. .::::::: :::.:..::::. CCDS41 VDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLL 120 130 140 150 160 170 180 190 200 pF1KB6 NPSSCGAEKQKGAKSSADCASLVPQCA . : CCDS41 SQSQRRLS 180 >>CCDS35114.1 RGS3 gene_id:5998|Hs108|chr9 (311 aa) initn: 591 init1: 546 opt: 595 Z-score: 712.5 bits: 139.4 E(32554): 2.3e-33 Smith-Waterman score: 595; 53.3% identity (81.4% similar) in 167 aa overlap (13-179:138-303) 10 20 30 40 pF1KB6 MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHNSSHNKK .. :::::..::.. ....: .: CCDS35 PICGPKVGGPTEMLRGMYLTRNGNLQRRHTMKEAKDMKNKLGIFRRRNES-PGAPPAGKA 110 120 130 140 150 160 50 60 70 80 90 100 pF1KB6 DKVVICQRVSQEEVKKWAESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIK ::.. . ..::. ::.::::.:. :. :::.:.:::..:.::::..::..::..::.: CCDS35 DKMMKSFKPTSEEALKWGESLEKLLVHKYGLAVFQAFLRTEFSEENLEFWLACEDFKKVK 170 180 190 200 210 220 110 120 130 140 150 160 pF1KB6 SPSKLSPKAKKIYNEFISVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEK : ::.. :::::. :.:..:: ::::::: :::.:. :. : ::: :::.::.:::: CCDS35 SQSKMASKAKKIFAEYIAIQACKEVNLDSYTREHTKDNLQSVTRGCFDLAQKRIFGLMEK 230 240 250 260 270 280 170 180 190 200 pF1KB6 DSYRRFLKSRFYLDLVNPSSCGAEKQKGAKSSADCASLVPQCA ::: :::.: .::::.: CCDS35 DSYPRFLRSDLYLDLINQKKMSPPL 290 300 310 >>CCDS6798.1 RGS3 gene_id:5998|Hs108|chr9 (519 aa) initn: 591 init1: 546 opt: 590 Z-score: 703.2 bits: 138.4 E(32554): 7.5e-33 Smith-Waterman score: 590; 54.3% identity (81.7% similar) in 164 aa overlap (16-179:349-511) 10 20 30 40 pF1KB6 MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHNSSHNKKDKV :::::..::.. ....: .: ::. CCDS67 LFFTGHRKMSGADTVGDDDEASRKRKSKNLAKDMKNKLGIFRRRNES-PGAPPAGKADKM 320 330 340 350 360 370 50 60 70 80 90 100 pF1KB6 VICQRVSQEEVKKWAESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPS . . ..::. ::.::::.:. :. :::.:.:::..:.::::..::..::..::.:: : CCDS67 MKSFKPTSEEALKWGESLEKLLVHKYGLAVFQAFLRTEFSEENLEFWLACEDFKKVKSQS 380 390 400 410 420 430 110 120 130 140 150 160 pF1KB6 KLSPKAKKIYNEFISVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSY :.. :::::. :.:..:: ::::::: :::.:. :. : ::: :::.::.::::::: CCDS67 KMASKAKKIFAEYIAIQACKEVNLDSYTREHTKDNLQSVTRGCFDLAQKRIFGLMEKDSY 440 450 460 470 480 490 170 180 190 200 pF1KB6 RRFLKSRFYLDLVNPSSCGAEKQKGAKSSADCASLVPQCA :::.: .::::.: CCDS67 PRFLRSDLYLDLINQKKMSPPL 500 510 >>CCDS65111.1 RGS3 gene_id:5998|Hs108|chr9 (591 aa) initn: 591 init1: 546 opt: 590 Z-score: 702.4 bits: 138.4 E(32554): 8.4e-33 Smith-Waterman score: 590; 54.3% identity (81.7% similar) in 164 aa overlap (16-179:421-583) 10 20 30 40 pF1KB6 MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHNSSHNKKDKV :::::..::.. ....: .: ::. CCDS65 AASPPDSKMSGADTVGDDDEASRKRKSKNLAKDMKNKLGIFRRRNES-PGAPPAGKADKM 400 410 420 430 440 50 60 70 80 90 100 pF1KB6 VICQRVSQEEVKKWAESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPS . . ..::. ::.::::.:. :. :::.:.:::..:.::::..::..::..::.:: : CCDS65 MKSFKPTSEEALKWGESLEKLLVHKYGLAVFQAFLRTEFSEENLEFWLACEDFKKVKSQS 450 460 470 480 490 500 110 120 130 140 150 160 pF1KB6 KLSPKAKKIYNEFISVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSY :.. :::::. :.:..:: ::::::: :::.:. :. : ::: :::.::.::::::: CCDS65 KMASKAKKIFAEYIAIQACKEVNLDSYTREHTKDNLQSVTRGCFDLAQKRIFGLMEKDSY 510 520 530 540 550 560 170 180 190 200 pF1KB6 RRFLKSRFYLDLVNPSSCGAEKQKGAKSSADCASLVPQCA :::.: .::::.: CCDS65 PRFLRSDLYLDLINQKKMSPPL 570 580 590 205 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 12:59:22 2016 done: Fri Nov 4 12:59:22 2016 Total Scan time: 1.470 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]