FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6919, 217 aa 1>>>pF1KB6919 217 - 217 aa - 217 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.2351+/-0.000388; mu= 5.7659+/- 0.024 mean_var=137.9905+/-27.983, 0's: 0 Z-trim(116.5): 13 B-trim: 309 in 1/53 Lambda= 0.109182 statistics sampled from 27683 (27695) to 27683 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.696), E-opt: 0.2 (0.325), width: 16 Scan time: 6.250 The best scores are: opt bits E(85289) NP_057640 (OMIM: 608665,614324) homologous-pairing ( 217) 1405 232.2 4.9e-61 NP_001242943 (OMIM: 608665,614324) homologous-pair ( 154) 1008 169.6 2.5e-42 NP_001242945 (OMIM: 608665,614324) homologous-pair ( 138) 894 151.6 5.8e-37 NP_001242944 (OMIM: 608665,614324) homologous-pair ( 138) 894 151.6 5.8e-37 NP_037422 (OMIM: 608665,614324) homologous-pairing ( 205) 737 127.0 2.2e-29 >>NP_057640 (OMIM: 608665,614324) homologous-pairing pro (217 aa) initn: 1405 init1: 1405 opt: 1405 Z-score: 1216.8 bits: 232.2 E(85289): 4.9e-61 Smith-Waterman score: 1405; 100.0% identity (100.0% similar) in 217 aa overlap (1-217:1-217) 10 20 30 40 50 60 pF1KB6 MSKGRAEAAAGAAGILLRYLQEQNRPYSSQDVFGNLQREHGLGKAVVVKTLEQLAQQGKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MSKGRAEAAAGAAGILLRYLQEQNRPYSSQDVFGNLQREHGLGKAVVVKTLEQLAQQGKI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KEKMYGKQKIYFADQDQFDMVSDADLQVLDGKIVALTAKVQSLQQSCRYMEAELKELSSA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 KEKMYGKQKIYFADQDQFDMVSDADLQVLDGKIVALTAKVQSLQQSCRYMEAELKELSSA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LTTPEMQKEIQELKKECAGYRERLKNIKAATNHVTPEEKEQVYRERQKYCKEWRKRKRMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 LTTPEMQKEIQELKKECAGYRERLKNIKAATNHVTPEEKEQVYRERQKYCKEWRKRKRMA 130 140 150 160 170 180 190 200 210 pF1KB6 TELSDAILEGYPKSKKQFFEEVGIETDEDYNVTLPDP ::::::::::::::::::::::::::::::::::::: NP_057 TELSDAILEGYPKSKKQFFEEVGIETDEDYNVTLPDP 190 200 210 >>NP_001242943 (OMIM: 608665,614324) homologous-pairing (154 aa) initn: 1008 init1: 1008 opt: 1008 Z-score: 880.9 bits: 169.6 E(85289): 2.5e-42 Smith-Waterman score: 1008; 100.0% identity (100.0% similar) in 154 aa overlap (64-217:1-154) 40 50 60 70 80 90 pF1KB6 GNLQREHGLGKAVVVKTLEQLAQQGKIKEKMYGKQKIYFADQDQFDMVSDADLQVLDGKI :::::::::::::::::::::::::::::: NP_001 MYGKQKIYFADQDQFDMVSDADLQVLDGKI 10 20 30 100 110 120 130 140 150 pF1KB6 VALTAKVQSLQQSCRYMEAELKELSSALTTPEMQKEIQELKKECAGYRERLKNIKAATNH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VALTAKVQSLQQSCRYMEAELKELSSALTTPEMQKEIQELKKECAGYRERLKNIKAATNH 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB6 VTPEEKEQVYRERQKYCKEWRKRKRMATELSDAILEGYPKSKKQFFEEVGIETDEDYNVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTPEEKEQVYRERQKYCKEWRKRKRMATELSDAILEGYPKSKKQFFEEVGIETDEDYNVT 100 110 120 130 140 150 pF1KB6 LPDP :::: NP_001 LPDP >>NP_001242945 (OMIM: 608665,614324) homologous-pairing (138 aa) initn: 894 init1: 894 opt: 894 Z-score: 784.6 bits: 151.6 E(85289): 5.8e-37 Smith-Waterman score: 894; 100.0% identity (100.0% similar) in 138 aa overlap (80-217:1-138) 50 60 70 80 90 100 pF1KB6 TLEQLAQQGKIKEKMYGKQKIYFADQDQFDMVSDADLQVLDGKIVALTAKVQSLQQSCRY :::::::::::::::::::::::::::::: NP_001 MVSDADLQVLDGKIVALTAKVQSLQQSCRY 10 20 30 110 120 130 140 150 160 pF1KB6 MEAELKELSSALTTPEMQKEIQELKKECAGYRERLKNIKAATNHVTPEEKEQVYRERQKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEAELKELSSALTTPEMQKEIQELKKECAGYRERLKNIKAATNHVTPEEKEQVYRERQKY 40 50 60 70 80 90 170 180 190 200 210 pF1KB6 CKEWRKRKRMATELSDAILEGYPKSKKQFFEEVGIETDEDYNVTLPDP :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CKEWRKRKRMATELSDAILEGYPKSKKQFFEEVGIETDEDYNVTLPDP 100 110 120 130 >>NP_001242944 (OMIM: 608665,614324) homologous-pairing (138 aa) initn: 894 init1: 894 opt: 894 Z-score: 784.6 bits: 151.6 E(85289): 5.8e-37 Smith-Waterman score: 894; 100.0% identity (100.0% similar) in 138 aa overlap (80-217:1-138) 50 60 70 80 90 100 pF1KB6 TLEQLAQQGKIKEKMYGKQKIYFADQDQFDMVSDADLQVLDGKIVALTAKVQSLQQSCRY :::::::::::::::::::::::::::::: NP_001 MVSDADLQVLDGKIVALTAKVQSLQQSCRY 10 20 30 110 120 130 140 150 160 pF1KB6 MEAELKELSSALTTPEMQKEIQELKKECAGYRERLKNIKAATNHVTPEEKEQVYRERQKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEAELKELSSALTTPEMQKEIQELKKECAGYRERLKNIKAATNHVTPEEKEQVYRERQKY 40 50 60 70 80 90 170 180 190 200 210 pF1KB6 CKEWRKRKRMATELSDAILEGYPKSKKQFFEEVGIETDEDYNVTLPDP :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CKEWRKRKRMATELSDAILEGYPKSKKQFFEEVGIETDEDYNVTLPDP 100 110 120 130 >>NP_037422 (OMIM: 608665,614324) homologous-pairing pro (205 aa) initn: 764 init1: 728 opt: 737 Z-score: 648.5 bits: 127.0 E(85289): 2.2e-29 Smith-Waterman score: 1303; 94.5% identity (94.5% similar) in 217 aa overlap (1-217:1-205) 10 20 30 40 50 60 pF1KB6 MSKGRAEAAAGAAGILLRYLQEQNRPYSSQDVFGNLQREHGLGKAVVVKTLEQLAQQGKI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 MSKGRAEAAAGAAGILLRYLQEQNRPYSSQDVFGNLQREHGLGKAVVVKTLEQLAQQGKI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KEKMYGKQKIYFADQDQFDMVSDADLQVLDGKIVALTAKVQSLQQSCRYMEAELKELSSA ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 KEKMYGKQKIYFADQDQFDMVSDADLQVLDGKIVALTAKVQSLQQSCRYMEAE------- 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 LTTPEMQKEIQELKKECAGYRERLKNIKAATNHVTPEEKEQVYRERQKYCKEWRKRKRMA ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 -----MQKEIQELKKECAGYRERLKNIKAATNHVTPEEKEQVYRERQKYCKEWRKRKRMA 120 130 140 150 160 190 200 210 pF1KB6 TELSDAILEGYPKSKKQFFEEVGIETDEDYNVTLPDP ::::::::::::::::::::::::::::::::::::: NP_037 TELSDAILEGYPKSKKQFFEEVGIETDEDYNVTLPDP 170 180 190 200 217 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 12:50:53 2016 done: Fri Nov 4 12:50:54 2016 Total Scan time: 6.250 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]