FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6922, 227 aa 1>>>pF1KB6922 227 - 227 aa - 227 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1675+/-0.000682; mu= 15.4316+/- 0.041 mean_var=69.7049+/-13.378, 0's: 0 Z-trim(110.6): 16 B-trim: 0 in 0/52 Lambda= 0.153618 statistics sampled from 11680 (11695) to 11680 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.729), E-opt: 0.2 (0.359), width: 16 Scan time: 2.230 The best scores are: opt bits E(32554) CCDS12249.1 TMED1 gene_id:11018|Hs108|chr19 ( 227) 1483 337.0 6e-93 CCDS743.1 TMED5 gene_id:50999|Hs108|chr1 ( 229) 814 188.7 2.6e-48 CCDS53342.1 TMED5 gene_id:50999|Hs108|chr1 ( 193) 552 130.6 6.8e-31 CCDS54888.1 TICAM2 gene_id:100302736|Hs108|chr5 ( 188) 256 65.0 3.7e-11 CCDS4120.1 TMED7 gene_id:51014|Hs108|chr5 ( 224) 256 65.1 4.3e-11 CCDS54887.1 TICAM2 gene_id:100302736|Hs108|chr5 ( 404) 256 65.2 6.9e-11 >>CCDS12249.1 TMED1 gene_id:11018|Hs108|chr19 (227 aa) initn: 1483 init1: 1483 opt: 1483 Z-score: 1782.2 bits: 337.0 E(32554): 6e-93 Smith-Waterman score: 1483; 100.0% identity (100.0% similar) in 227 aa overlap (1-227:1-227) 10 20 30 40 50 60 pF1KB6 MMAAGAALALALWLLMPPVEVGGAGPPPIQDGEFTFLLPAGRKQCFYQSAPANASLETEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MMAAGAALALALWLLMPPVEVGGAGPPPIQDGEFTFLLPAGRKQCFYQSAPANASLETEY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 QVIGGAGLDVDFTLESPQGVLLVSESRKADGVHTVEPTEAGDYKLCFDNSFSTISEKLVF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 QVIGGAGLDVDFTLESPQGVLLVSESRKADGVHTVEPTEAGDYKLCFDNSFSTISEKLVF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 FELIFDSLQDDEEVEGWAEAVEPEEMLDVKMEDIKESIETMRTRLERSIQMLTLLRAFEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 FELIFDSLQDDEEVEGWAEAVEPEEMLDVKMEDIKESIETMRTRLERSIQMLTLLRAFEA 130 140 150 160 170 180 190 200 210 220 pF1KB6 RDRNLQEGNLERVNFWSAVNVAVLLLVAVLQVCTLKRFFQDKRPVPT ::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 RDRNLQEGNLERVNFWSAVNVAVLLLVAVLQVCTLKRFFQDKRPVPT 190 200 210 220 >>CCDS743.1 TMED5 gene_id:50999|Hs108|chr1 (229 aa) initn: 629 init1: 629 opt: 814 Z-score: 980.8 bits: 188.7 E(32554): 2.6e-48 Smith-Waterman score: 814; 58.1% identity (82.9% similar) in 210 aa overlap (16-223:17-225) 10 20 30 40 50 pF1KB6 MMAAGAALALALWLLMPPVEV-GGAGPPPIQDGEFTFLLPAGRKQCFYQSAPANASLET .::: . :.:: : :..::: ::::.:.:::: : .:::: CCDS74 MGDKIWLPFPVLLLAALPPVLLPGAAGFTPSLDSDFTFTLPAGQKECFYQPMPLKASLEI 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 EYQVIGGAGLDVDFTLESPQGVLLVSESRKADGVHTVEPTEAGDYKLCFDNSFSTISEKL ::::. :::::.:: : ::.: :: :.::.::::::: ::.::: .::::.:::::::. CCDS74 EYQVLDGAGLDIDFHLASPEGKTLVFEQRKSDGVHTVE-TEVGDYMFCFDNTFSTISEKV 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 VFFELIFDSLQDD-EEVEGWAEAVEPEEMLDVKMEDIKESIETMRTRLERSIQMLTLLRA .:::::.:.. .. .: : : . . ..::.:.::: :::.....:: .: .. ::::: CCDS74 IFFELILDNMGEQAQEQEDWKKYITGTDILDMKLEDILESINSIKSRLSKSGHIQTLLRA 120 130 140 150 160 170 180 190 200 210 220 pF1KB6 FEARDRNLQEGNLERVNFWSAVNVAVLLLVAVLQVCTLKRFFQDKRPVPT :::::::.::.:..:::::: ::..:...:...:: :: .:.::: CCDS74 FEARDRNIQESNFDRVNFWSMVNLVVMVVVSAIQVYMLKSLFEDKRKSRT 180 190 200 210 220 >>CCDS53342.1 TMED5 gene_id:50999|Hs108|chr1 (193 aa) initn: 560 init1: 359 opt: 552 Z-score: 668.1 bits: 130.6 E(32554): 6.8e-31 Smith-Waterman score: 552; 57.9% identity (79.3% similar) in 145 aa overlap (16-158:17-160) 10 20 30 40 50 pF1KB6 MMAAGAALALALWLLMPPVEV-GGAGPPPIQDGEFTFLLPAGRKQCFYQSAPANASLET .::: . :.:: : :..::: ::::.:.:::: : .:::: CCDS53 MGDKIWLPFPVLLLAALPPVLLPGAAGFTPSLDSDFTFTLPAGQKECFYQPMPLKASLEI 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 EYQVIGGAGLDVDFTLESPQGVLLVSESRKADGVHTVEPTEAGDYKLCFDNSFSTISEKL ::::. :::::.:: : ::.: :: :.::.::::::: ::.::: .::::.:::::::. CCDS53 EYQVLDGAGLDIDFHLASPEGKTLVFEQRKSDGVHTVE-TEVGDYMFCFDNTFSTISEKV 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 VFFELIFDSLQDD-EEVEGWAEAVEPEEMLDVKMEDIKESIETMRTRLERSIQMLTLLRA .:::::.:.. .. .: : : . . ..::.:.::: . : CCDS53 IFFELILDNMGEQAQEQEDWKKYITGTDILDMKLEDILDPIIKIASDVQIRLHLGIHQQH 120 130 140 150 160 170 180 190 200 210 220 pF1KB6 FEARDRNLQEGNLERVNFWSAVNVAVLLLVAVLQVCTLKRFFQDKRPVPT CCDS53 QVQTKQKWAHTNSA 180 190 >>CCDS54888.1 TICAM2 gene_id:100302736|Hs108|chr5 (188 aa) initn: 260 init1: 240 opt: 256 Z-score: 313.7 bits: 65.0 E(32554): 3.7e-11 Smith-Waterman score: 268; 33.7% identity (55.6% similar) in 187 aa overlap (10-195:22-188) 10 20 30 40 pF1KB6 MMAAGAALALALWLLMP-PVEVGGAGPPPIQDGEFTFLLPAGRKQCFY ::: ::.: : :::. :.:: :: . ::::: CCDS54 MPRPGSAQRWAAVAGRWGCRLLALLLLVPGP---GGAS-------EITFELPDNAKQCFY 10 20 30 40 50 50 60 70 80 90 100 pF1KB6 QSAPANASLETEYQVIGGAGLDVDFTLESPQGVLLVSESRKADGVHTVEPTEAGDYKLCF .. ... :.::: :. ::: ::.:.: .: .: .: : .. : ::.:: CCDS54 EDIAQGTKCTLEFQVITGGHYDVDCRLEDPDGKVLYKEMKKQYDSFTFTASKNGTYKFCF 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB6 DNSFSTISEKLVFFELIFDSLQDDEEVEGWAEAVEPEEMLDVKMEDIKESIETMRTRLER .: :::...: :.: : .: : . : : . ... . ... :. CCDS54 SNEFSTFTHKTVYF---------DFQV-GEDPPLFPSENRVSALTQMESACVSIHEALKS 120 130 140 150 160 170 180 190 200 210 220 pF1KB6 SIQMLTLLRAFEARDRNLQEGNLERVNFWSAVNVAVLLLVAVLQVCTLKRFFQDKRPVPT :.. : .: ::. :. : :: . CCDS54 VIDYQTHFRLREAQGRSRAEDLNTRVAY 170 180 >>CCDS4120.1 TMED7 gene_id:51014|Hs108|chr5 (224 aa) initn: 372 init1: 246 opt: 256 Z-score: 312.6 bits: 65.1 E(32554): 4.3e-11 Smith-Waterman score: 362; 35.6% identity (58.4% similar) in 219 aa overlap (10-227:22-220) 10 20 30 40 pF1KB6 MMAAGAALALALWLLMP-PVEVGGAGPPPIQDGEFTFLLPAGRKQCFY ::: ::.: : :::. :.:: :: . ::::: CCDS41 MPRPGSAQRWAAVAGRWGCRLLALLLLVPGP---GGAS-------EITFELPDNAKQCFY 10 20 30 40 50 50 60 70 80 90 100 pF1KB6 QSAPANASLETEYQVIGGAGLDVDFTLESPQGVLLVSESRKADGVHTVEPTEAGDYKLCF .. ... :.::: :. ::: ::.:.: .: .: .: : .. : ::.:: CCDS41 EDIAQGTKCTLEFQVITGGHYDVDCRLEDPDGKVLYKEMKKQYDSFTFTASKNGTYKFCF 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB6 DNSFSTISEKLVFFELIFDSLQDDEEVEGWAEAVEPEEMLDVKMEDIKESIETMRTRLER .: :::...: :.: : .: : . : : . ... . ... :. CCDS41 SNEFSTFTHKTVYF---------DFQV-GEDPPLFPSENRVSALTQMESACVSIHEALKS 120 130 140 150 160 170 180 190 200 210 220 pF1KB6 SIQMLTLLRAFEARDRNLQEGNLERVNFWSAVNVAVLLLVAVLQVCTLKRFFQDKRPVPT :.. : .: ::. :. : :: .::. .. .::.:.. :: :: ::.::: . : CCDS41 VIDYQTHFRLREAQGRSRAEDLNTRVAYWSVGEALILLVVSIGQVFLLKSFFSDKRTTTT 170 180 190 200 210 220 CCDS41 RVGS >>CCDS54887.1 TICAM2 gene_id:100302736|Hs108|chr5 (404 aa) initn: 288 init1: 240 opt: 256 Z-score: 309.0 bits: 65.2 E(32554): 6.9e-11 Smith-Waterman score: 291; 33.5% identity (56.7% similar) in 194 aa overlap (10-202:22-195) 10 20 30 40 pF1KB6 MMAAGAALALALWLLMP-PVEVGGAGPPPIQDGEFTFLLPAGRKQCFY ::: ::.: : :::. :.:: :: . ::::: CCDS54 MPRPGSAQRWAAVAGRWGCRLLALLLLVPGP---GGAS-------EITFELPDNAKQCFY 10 20 30 40 50 50 60 70 80 90 100 pF1KB6 QSAPANASLETEYQVIGGAGLDVDFTLESPQGVLLVSESRKADGVHTVEPTEAGDYKLCF .. ... :.::: :. ::: ::.:.: .: .: .: : .. : ::.:: CCDS54 EDIAQGTKCTLEFQVITGGHYDVDCRLEDPDGKVLYKEMKKQYDSFTFTASKNGTYKFCF 60 70 80 90 100 110 110 120 130 140 150 160 pF1KB6 DNSFSTISEKLVFFELIFDSLQDDEEVEGWAEAVEPEEMLDVKMEDIKESIETMRTRLER .: :::...: :.: : .: : . : : . ... . ... :. CCDS54 SNEFSTFTHKTVYF---------DFQV-GEDPPLFPSENRVSALTQMESACVSIHEALKS 120 130 140 150 160 170 180 190 200 210 220 pF1KB6 SIQMLTLLRAFEARDRNLQEGNLERVNFWSAVNVAVLLLVAVLQVCTLKRFFQDKRPVPT :.. : .: ::. :. : :: .: .:... CCDS54 VIDYQTHFRLREAQGRSRAEDLNTRVAYWHSVDTSPGYHESDSKKSEDLSLCNVAEHSNT 170 180 190 200 210 220 CCDS54 TEGPTGKQEGAQSVEEMFEEEAEEEVFLKFVILHAEDDTDEALRVQNLLQDDFGIKPGII 230 240 250 260 270 280 227 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 14:24:00 2016 done: Sat Nov 5 14:24:00 2016 Total Scan time: 2.230 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]