FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6923, 205 aa 1>>>pF1KB6923 205 - 205 aa - 205 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6013+/-0.000435; mu= 11.6096+/- 0.027 mean_var=60.0288+/-11.410, 0's: 0 Z-trim(109.5): 44 B-trim: 0 in 0/50 Lambda= 0.165537 statistics sampled from 17719 (17733) to 17719 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.592), E-opt: 0.2 (0.208), width: 16 Scan time: 5.660 The best scores are: opt bits E(85289) NP_002349 (OMIM: 601467) mitotic spindle assembly ( 205) 1307 320.7 1e-87 XP_011538809 (OMIM: 604094) PREDICTED: mitotic spi ( 211) 178 51.1 1.6e-06 NP_006332 (OMIM: 604094) mitotic spindle assembly ( 211) 178 51.1 1.6e-06 NP_001120797 (OMIM: 604094) mitotic spindle assemb ( 211) 178 51.1 1.6e-06 >>NP_002349 (OMIM: 601467) mitotic spindle assembly chec (205 aa) initn: 1307 init1: 1307 opt: 1307 Z-score: 1695.7 bits: 320.7 E(85289): 1e-87 Smith-Waterman score: 1307; 100.0% identity (100.0% similar) in 205 aa overlap (1-205:1-205) 10 20 30 40 50 60 pF1KB6 MALQLSREQGITLRGSAEIVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLVTTDLE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MALQLSREQGITLRGSAEIVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLVTTDLE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LIKYLNNVVEQLKDWLYKCSVQKLVVVISNIESGEVLERWQFDIECDKTAKDDSAPREKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LIKYLNNVVEQLKDWLYKCSVQKLVVVISNIESGEVLERWQFDIECDKTAKDDSAPREKS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 QKAIQDEIRSVIRQITATVTFLPLLEVSCSFDLLIYTDKDLVVPEKWEESGPQFITNSEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 QKAIQDEIRSVIRQITATVTFLPLLEVSCSFDLLIYTDKDLVVPEKWEESGPQFITNSEE 130 140 150 160 170 180 190 200 pF1KB6 VRLRSFTTTIHKVNSMVAYKIPVND ::::::::::::::::::::::::: NP_002 VRLRSFTTTIHKVNSMVAYKIPVND 190 200 >>XP_011538809 (OMIM: 604094) PREDICTED: mitotic spindle (211 aa) initn: 161 init1: 136 opt: 178 Z-score: 238.3 bits: 51.1 E(85289): 1.6e-06 Smith-Waterman score: 178; 27.0% identity (60.3% similar) in 141 aa overlap (17-157:16-152) 10 20 30 40 50 60 pF1KB6 MALQLSREQGITLRGSAEIVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLVTTDLE :... ::. ... ::: : .:: : . .::.. . .. : XP_011 MTTLTRQDLNFGQVVADVLCEFLEVAVHLILYVREVYPVGIFQKRKKYNVPVQMSCHPE 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 LIKYLNNVVEQLKDWLYKCSVQKLVVVISNIESGEVLERWQFDIECDKTAKDDSAPREKS : .:...... .: : : .:.:.:::: . : : :.. :.: : .. XP_011 LNQYIQDTLHCVKPLLEKNDVEKVVVVILDKEHRPV-EKFVFEITQPPLL---SISSDSL 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 QKAIQDEIRSVIRQITATVTFLPLLEVSCSFDLLIYTDKDLVVPEKWEESGPQFITNSEE . ... .:. : .:.. . : .:.: .:..: XP_011 LSHVEQLLRAFILKISVCDAVLDHNPPGCTFTVLVHTREAATRNMEKIQVIKDFPWILAD 120 130 140 150 160 170 190 200 pF1KB6 VRLRSFTTTIHKVNSMVAYKIPVND XP_011 EQDVHMHDPRLIPLKTMTSDILKMQLYVEERAHKGS 180 190 200 210 >>NP_006332 (OMIM: 604094) mitotic spindle assembly chec (211 aa) initn: 161 init1: 136 opt: 178 Z-score: 238.3 bits: 51.1 E(85289): 1.6e-06 Smith-Waterman score: 178; 27.0% identity (60.3% similar) in 141 aa overlap (17-157:16-152) 10 20 30 40 50 60 pF1KB6 MALQLSREQGITLRGSAEIVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLVTTDLE :... ::. ... ::: : .:: : . .::.. . .. : NP_006 MTTLTRQDLNFGQVVADVLCEFLEVAVHLILYVREVYPVGIFQKRKKYNVPVQMSCHPE 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 LIKYLNNVVEQLKDWLYKCSVQKLVVVISNIESGEVLERWQFDIECDKTAKDDSAPREKS : .:...... .: : : .:.:.:::: . : : :.. :.: : .. NP_006 LNQYIQDTLHCVKPLLEKNDVEKVVVVILDKEHRPV-EKFVFEITQPPLL---SISSDSL 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 QKAIQDEIRSVIRQITATVTFLPLLEVSCSFDLLIYTDKDLVVPEKWEESGPQFITNSEE . ... .:. : .:.. . : .:.: .:..: NP_006 LSHVEQLLRAFILKISVCDAVLDHNPPGCTFTVLVHTREAATRNMEKIQVIKDFPWILAD 120 130 140 150 160 170 190 200 pF1KB6 VRLRSFTTTIHKVNSMVAYKIPVND NP_006 EQDVHMHDPRLIPLKTMTSDILKMQLYVEERAHKGS 180 190 200 210 >>NP_001120797 (OMIM: 604094) mitotic spindle assembly c (211 aa) initn: 161 init1: 136 opt: 178 Z-score: 238.3 bits: 51.1 E(85289): 1.6e-06 Smith-Waterman score: 178; 27.0% identity (60.3% similar) in 141 aa overlap (17-157:16-152) 10 20 30 40 50 60 pF1KB6 MALQLSREQGITLRGSAEIVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLVTTDLE :... ::. ... ::: : .:: : . .::.. . .. : NP_001 MTTLTRQDLNFGQVVADVLCEFLEVAVHLILYVREVYPVGIFQKRKKYNVPVQMSCHPE 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 LIKYLNNVVEQLKDWLYKCSVQKLVVVISNIESGEVLERWQFDIECDKTAKDDSAPREKS : .:...... .: : : .:.:.:::: . : : :.. :.: : .. NP_001 LNQYIQDTLHCVKPLLEKNDVEKVVVVILDKEHRPV-EKFVFEITQPPLL---SISSDSL 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 QKAIQDEIRSVIRQITATVTFLPLLEVSCSFDLLIYTDKDLVVPEKWEESGPQFITNSEE . ... .:. : .:.. . : .:.: .:..: NP_001 LSHVEQLLRAFILKISVCDAVLDHNPPGCTFTVLVHTREAATRNMEKIQVIKDFPWILAD 120 130 140 150 160 170 190 200 pF1KB6 VRLRSFTTTIHKVNSMVAYKIPVND NP_001 EQDVHMHDPRLIPLKTMTSDILKMQLYVEERAHKGS 180 190 200 210 205 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 12:34:37 2016 done: Fri Nov 4 12:34:38 2016 Total Scan time: 5.660 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]