FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6925, 205 aa 1>>>pF1KB6925 205 - 205 aa - 205 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.2334+/-0.000339; mu= 5.3403+/- 0.021 mean_var=122.9338+/-24.207, 0's: 0 Z-trim(118.6): 5 B-trim: 16 in 2/51 Lambda= 0.115675 statistics sampled from 31811 (31816) to 31811 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.728), E-opt: 0.2 (0.373), width: 16 Scan time: 6.010 The best scores are: opt bits E(85289) NP_006232 (OMIM: 601792) protein phosphatase inhib ( 205) 1332 232.6 3.5e-61 NP_001278433 (OMIM: 601792) protein phosphatase in ( 206) 1315 229.8 2.5e-60 XP_006713745 (OMIM: 601792) PREDICTED: protein pho ( 142) 891 158.9 3.6e-39 NP_001303254 (OMIM: 601792) protein phosphatase in ( 185) 839 150.3 1.9e-36 NP_001278434 (OMIM: 601792) protein phosphatase in ( 179) 662 120.7 1.4e-27 >>NP_006232 (OMIM: 601792) protein phosphatase inhibitor (205 aa) initn: 1332 init1: 1332 opt: 1332 Z-score: 1219.5 bits: 232.6 E(85289): 3.5e-61 Smith-Waterman score: 1332; 100.0% identity (100.0% similar) in 205 aa overlap (1-205:1-205) 10 20 30 40 50 60 pF1KB6 MAASTASHRPIKGILKNKTSTTSSMVASAEQPRGNVDEELSKKSQKWDEMNILATYHPAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MAASTASHRPIKGILKNKTSTTSSMVASAEQPRGNVDEELSKKSQKWDEMNILATYHPAD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KDYGLMKIDEPSTPYHSMMGDDEDACSDTEATEAMAPDILARKLAAAEGLEPKYRIQEQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 KDYGLMKIDEPSTPYHSMMGDDEDACSDTEATEAMAPDILARKLAAAEGLEPKYRIQEQE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 SSGEEDSDLSPEEREKKRQFEMKRKLHYNEGLNIKLARQLISKDLHDDDEDEEMLETADG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 SSGEEDSDLSPEEREKKRQFEMKRKLHYNEGLNIKLARQLISKDLHDDDEDEEMLETADG 130 140 150 160 170 180 190 200 pF1KB6 ESMNTEESNQGSTPSDQQQNKLRSS ::::::::::::::::::::::::: NP_006 ESMNTEESNQGSTPSDQQQNKLRSS 190 200 >>NP_001278433 (OMIM: 601792) protein phosphatase inhibi (206 aa) initn: 886 init1: 886 opt: 1315 Z-score: 1204.1 bits: 229.8 E(85289): 2.5e-60 Smith-Waterman score: 1315; 99.0% identity (99.5% similar) in 206 aa overlap (1-205:1-206) 10 20 30 40 50 60 pF1KB6 MAASTASHRPIKGILKNKTSTTSSMVASAEQPRGNVDEELSKKSQKWDEMNILATYHPAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAASTASHRPIKGILKNKTSTTSSMVASAEQPRGNVDEELSKKSQKWDEMNILATYHPAD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KDYGLMKIDEPSTPYHSMMGDDEDACSDTEATEAMAPDILARKLAAAEGLEPKYRIQEQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KDYGLMKIDEPSTPYHSMMGDDEDACSDTEATEAMAPDILARKLAAAEGLEPKYRIQEQE 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 SSGEEDSDLSPEER-EKKRQFEMKRKLHYNEGLNIKLARQLISKDLHDDDEDEEMLETAD :::::::::::::: .:::::::::::::::::::::::::::::::::::::::::::: NP_001 SSGEEDSDLSPEERGKKKRQFEMKRKLHYNEGLNIKLARQLISKDLHDDDEDEEMLETAD 130 140 150 160 170 180 180 190 200 pF1KB6 GESMNTEESNQGSTPSDQQQNKLRSS :::::::::::::::::::::::::: NP_001 GESMNTEESNQGSTPSDQQQNKLRSS 190 200 >>XP_006713745 (OMIM: 601792) PREDICTED: protein phospha (142 aa) initn: 891 init1: 891 opt: 891 Z-score: 824.1 bits: 158.9 E(85289): 3.6e-39 Smith-Waterman score: 891; 100.0% identity (100.0% similar) in 137 aa overlap (1-137:1-137) 10 20 30 40 50 60 pF1KB6 MAASTASHRPIKGILKNKTSTTSSMVASAEQPRGNVDEELSKKSQKWDEMNILATYHPAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MAASTASHRPIKGILKNKTSTTSSMVASAEQPRGNVDEELSKKSQKWDEMNILATYHPAD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KDYGLMKIDEPSTPYHSMMGDDEDACSDTEATEAMAPDILARKLAAAEGLEPKYRIQEQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KDYGLMKIDEPSTPYHSMMGDDEDACSDTEATEAMAPDILARKLAAAEGLEPKYRIQEQE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 SSGEEDSDLSPEEREKKRQFEMKRKLHYNEGLNIKLARQLISKDLHDDDEDEEMLETADG ::::::::::::::::: XP_006 SSGEEDSDLSPEEREKKSDNLK 130 140 >>NP_001303254 (OMIM: 601792) protein phosphatase inhibi (185 aa) initn: 834 init1: 834 opt: 839 Z-score: 775.5 bits: 150.3 E(85289): 1.9e-36 Smith-Waterman score: 839; 98.5% identity (98.5% similar) in 132 aa overlap (74-205:54-185) 50 60 70 80 90 100 pF1KB6 SQKWDEMNILATYHPADKDYGLMKIDEPSTPYHSMMGDDEDACSDTEATEAMAPDILARK : ::::::::::::::::::::::::::: NP_001 WLCCPVQWLLTGTVIAHYSLELPTQVILPPPPPSMMGDDEDACSDTEATEAMAPDILARK 30 40 50 60 70 80 110 120 130 140 150 160 pF1KB6 LAAAEGLEPKYRIQEQESSGEEDSDLSPEEREKKRQFEMKRKLHYNEGLNIKLARQLISK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAAAEGLEPKYRIQEQESSGEEDSDLSPEEREKKRQFEMKRKLHYNEGLNIKLARQLISK 90 100 110 120 130 140 170 180 190 200 pF1KB6 DLHDDDEDEEMLETADGESMNTEESNQGSTPSDQQQNKLRSS :::::::::::::::::::::::::::::::::::::::::: NP_001 DLHDDDEDEEMLETADGESMNTEESNQGSTPSDQQQNKLRSS 150 160 170 180 >>NP_001278434 (OMIM: 601792) protein phosphatase inhibi (179 aa) initn: 659 init1: 659 opt: 662 Z-score: 616.1 bits: 120.7 E(85289): 1.4e-27 Smith-Waterman score: 1095; 86.8% identity (87.3% similar) in 205 aa overlap (1-205:1-179) 10 20 30 40 50 60 pF1KB6 MAASTASHRPIKGILKNKTSTTSSMVASAEQPRGNVDEELSKKSQKWDEMNILATYHPAD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAASTASHRPIKGILKNKTSTTSSMVASAEQPRGNVDEELSKKSQKWDEMNILATYHPAD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KDYGLMKIDEPSTPYHSMMGDDEDACSDTEATEAMAPDILARKLAAAEGLEPKYRIQEQE :::::::::::::::: .::::::::::::::::: NP_001 KDYGLMKIDEPSTPYH--------------------------RLAAAEGLEPKYRIQEQE 70 80 90 130 140 150 160 170 180 pF1KB6 SSGEEDSDLSPEEREKKRQFEMKRKLHYNEGLNIKLARQLISKDLHDDDEDEEMLETADG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSGEEDSDLSPEEREKKRQFEMKRKLHYNEGLNIKLARQLISKDLHDDDEDEEMLETADG 100 110 120 130 140 150 190 200 pF1KB6 ESMNTEESNQGSTPSDQQQNKLRSS ::::::::::::::::::::::::: NP_001 ESMNTEESNQGSTPSDQQQNKLRSS 160 170 205 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 12:17:55 2016 done: Fri Nov 4 12:17:56 2016 Total Scan time: 6.010 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]