Result of FASTA (omim) for
pF1KB6927
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6927, 207 aa
1>>>pF1KB6927 207 - 207 aa - 207 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5068+/-0.000398; mu= 7.6379+/- 0.024
mean_var=171.7491+/-37.308, 0's: 0 Z-trim(116.8): 469 B-trim: 1026 in 2/52
Lambda= 0.097865
statistics sampled from 27476 (28237) to 27476 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.712), E-opt: 0.2 (0.331), width: 16
Scan time: 4.170
The best scores are: opt bits E(85289)
NP_071448 (OMIM: 612331) protein lin-7 homolog B i ( 207) 1319 198.1 8.7e-51
NP_060832 (OMIM: 612332) protein lin-7 homolog C [ ( 197) 1109 168.4 7.1e-42
NP_004655 (OMIM: 603380) protein lin-7 homolog A i ( 233) 1038 158.5 8.2e-39
XP_006723386 (OMIM: 612331) PREDICTED: protein lin ( 183) 847 131.4 9.2e-31
NP_001311352 (OMIM: 603380) protein lin-7 homolog ( 162) 795 124.0 1.4e-28
XP_011537230 (OMIM: 603380) PREDICTED: protein lin ( 186) 768 120.2 2.1e-27
NP_001295348 (OMIM: 612331) protein lin-7 homolog ( 137) 503 82.6 3.2e-16
XP_016882620 (OMIM: 612331) PREDICTED: protein lin ( 105) 335 58.8 3.7e-09
XP_016872775 (OMIM: 603583) PREDICTED: disks large ( 757) 293 53.9 8e-07
XP_016872773 (OMIM: 603583) PREDICTED: disks large ( 801) 293 53.9 8.3e-07
XP_016872772 (OMIM: 603583) PREDICTED: disks large ( 810) 293 53.9 8.4e-07
XP_016872771 (OMIM: 603583) PREDICTED: disks large ( 811) 293 53.9 8.4e-07
XP_005273868 (OMIM: 603583) PREDICTED: disks large ( 819) 293 53.9 8.4e-07
XP_005273867 (OMIM: 603583) PREDICTED: disks large ( 837) 293 53.9 8.6e-07
XP_016872766 (OMIM: 603583) PREDICTED: disks large ( 842) 293 53.9 8.6e-07
XP_016872765 (OMIM: 603583) PREDICTED: disks large ( 848) 293 53.9 8.6e-07
NP_001287912 (OMIM: 603583) disks large homolog 2 ( 852) 293 53.9 8.7e-07
XP_016872763 (OMIM: 603583) PREDICTED: disks large ( 866) 293 54.0 8.8e-07
NP_001355 (OMIM: 603583) disks large homolog 2 iso ( 870) 293 54.0 8.8e-07
XP_016872761 (OMIM: 603583) PREDICTED: disks large ( 871) 293 54.0 8.8e-07
XP_016872760 (OMIM: 603583) PREDICTED: disks large ( 872) 293 54.0 8.8e-07
XP_016872759 (OMIM: 603583) PREDICTED: disks large ( 873) 293 54.0 8.8e-07
NP_001136172 (OMIM: 603583) disks large homolog 2 ( 749) 292 53.7 8.8e-07
XP_016872758 (OMIM: 603583) PREDICTED: disks large ( 880) 293 54.0 8.8e-07
XP_016872757 (OMIM: 603583) PREDICTED: disks large ( 883) 293 54.0 8.9e-07
XP_016872756 (OMIM: 603583) PREDICTED: disks large ( 884) 293 54.0 8.9e-07
XP_016872755 (OMIM: 603583) PREDICTED: disks large ( 891) 293 54.0 8.9e-07
XP_011543084 (OMIM: 603583) PREDICTED: disks large ( 891) 293 54.0 8.9e-07
XP_011543090 (OMIM: 603583) PREDICTED: disks large ( 767) 292 53.8 8.9e-07
XP_016872754 (OMIM: 603583) PREDICTED: disks large ( 903) 293 54.0 9e-07
XP_016872753 (OMIM: 603583) PREDICTED: disks large ( 904) 293 54.0 9e-07
XP_016872752 (OMIM: 603583) PREDICTED: disks large ( 905) 293 54.0 9e-07
NP_001193698 (OMIM: 603583) disks large homolog 2 ( 909) 293 54.0 9e-07
XP_016872751 (OMIM: 603583) PREDICTED: disks large ( 923) 293 54.0 9.1e-07
XP_016872774 (OMIM: 603583) PREDICTED: disks large ( 796) 292 53.8 9.1e-07
XP_016872769 (OMIM: 603583) PREDICTED: disks large ( 820) 292 53.8 9.3e-07
XP_016872770 (OMIM: 603583) PREDICTED: disks large ( 820) 292 53.8 9.3e-07
XP_016872768 (OMIM: 603583) PREDICTED: disks large ( 821) 292 53.8 9.3e-07
XP_016872749 (OMIM: 603583) PREDICTED: disks large ( 968) 293 54.0 9.4e-07
XP_016872748 (OMIM: 603583) PREDICTED: disks large ( 969) 293 54.0 9.4e-07
NP_001136171 (OMIM: 603583) disks large homolog 2 ( 975) 293 54.0 9.4e-07
XP_016872767 (OMIM: 603583) PREDICTED: disks large ( 839) 292 53.8 9.5e-07
XP_016872747 (OMIM: 603583) PREDICTED: disks large ( 985) 293 54.0 9.5e-07
XP_016872764 (OMIM: 603583) PREDICTED: disks large ( 857) 292 53.8 9.6e-07
XP_011543082 (OMIM: 603583) PREDICTED: disks large (1007) 293 54.0 9.6e-07
XP_016872762 (OMIM: 603583) PREDICTED: disks large ( 871) 292 53.8 9.7e-07
XP_016872746 (OMIM: 603583) PREDICTED: disks large (1025) 293 54.0 9.7e-07
XP_011543080 (OMIM: 603583) PREDICTED: disks large (1025) 293 54.0 9.7e-07
XP_016872744 (OMIM: 603583) PREDICTED: disks large (1026) 293 54.0 9.8e-07
XP_016872745 (OMIM: 603583) PREDICTED: disks large (1026) 293 54.0 9.8e-07
>>NP_071448 (OMIM: 612331) protein lin-7 homolog B isofo (207 aa)
initn: 1319 init1: 1319 opt: 1319 Z-score: 1032.8 bits: 198.1 E(85289): 8.7e-51
Smith-Waterman score: 1319; 100.0% identity (100.0% similar) in 207 aa overlap (1-207:1-207)
10 20 30 40 50 60
pF1KB6 MAALVEPLGLERDVSRAVELLERLQRSGELPPQKLQALQRVLQSRFCSAIREVYEQLYDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MAALVEPLGLERDVSRAVELLERLQRSGELPPQKLQALQRVLQSRFCSAIREVYEQLYDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 LDITGSAEIRAHATAKATVAAFTASEGHAHPRVVELPKTDEGLGFNIMGGKEQNSPIYIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 LDITGSAEIRAHATAKATVAAFTASEGHAHPRVVELPKTDEGLGFNIMGGKEQNSPIYIS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 RVIPGGVADRHGGLKRGDQLLSVNGVSVEGEQHEKAVELLKAAQGSVKLVVRYTPRVLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 RVIPGGVADRHGGLKRGDQLLSVNGVSVEGEQHEKAVELLKAAQGSVKLVVRYTPRVLEE
130 140 150 160 170 180
190 200
pF1KB6 MEARFEKMRSARRRQQHQSYSSLESRG
:::::::::::::::::::::::::::
NP_071 MEARFEKMRSARRRQQHQSYSSLESRG
190 200
>>NP_060832 (OMIM: 612332) protein lin-7 homolog C [Homo (197 aa)
initn: 1109 init1: 1109 opt: 1109 Z-score: 872.8 bits: 168.4 E(85289): 7.1e-42
Smith-Waterman score: 1109; 84.7% identity (98.0% similar) in 196 aa overlap (1-196:1-196)
10 20 30 40 50 60
pF1KB6 MAALVEPLGLERDVSRAVELLERLQRSGELPPQKLQALQRVLQSRFCSAIREVYEQLYDT
:::: ::. ::::. ::.::::.::::::.::::::::::::::.::.:.:::::..:.:
NP_060 MAALGEPVRLERDICRAIELLEKLQRSGEVPPQKLQALQRVLQSEFCNAVREVYEHVYET
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 LDITGSAEIRAHATAKATVAAFTASEGHAHPRVVELPKTDEGLGFNIMGGKEQNSPIYIS
.::..: :.::.::::::::::.:::::.::::::::::.::::::::::::::::::::
NP_060 VDISSSPEVRANATAKATVAAFAASEGHSHPRVVELPKTEEGLGFNIMGGKEQNSPIYIS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 RVIPGGVADRHGGLKRGDQLLSVNGVSVEGEQHEKAVELLKAAQGSVKLVVRYTPRVLEE
:.::::.::::::::::::::::::::::::.:::::::::::::.:::::::::.::::
NP_060 RIIPGGIADRHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAQGKVKLVVRYTPKVLEE
130 140 150 160 170 180
190 200
pF1KB6 MEARFEKMRSARRRQQHQSYSSLESRG
::.::::::::.::::
NP_060 MESRFEKMRSAKRRQQT
190
>>NP_004655 (OMIM: 603380) protein lin-7 homolog A isofo (233 aa)
initn: 1082 init1: 1028 opt: 1038 Z-score: 817.8 bits: 158.5 E(85289): 8.2e-39
Smith-Waterman score: 1038; 78.5% identity (95.5% similar) in 200 aa overlap (1-198:14-213)
10 20 30 40
pF1KB6 MAAL--VEPLGLERDVSRAVELLERLQRSGELPPQKLQALQRVLQSR
::.: :.:: :.:::.::.::::.::.:::.: .:::.:..::::.
NP_004 MLKPSVTSAPTADMATLTVVQPLTLDRDVARAIELLEKLQESGEVPVHKLQSLKKVLQSE
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB6 FCSAIREVYEQLYDTLDITGSAEIRAHATAKATVAAFTASEGHAHPRVVELPKTDEGLGF
::.::::::. ...:. ..: :.::.::::::::::.:::::.::::::::::::::::
NP_004 FCTAIREVYQYMHETITVNGCPEFRARATAKATVAAFAASEGHSHPRVVELPKTDEGLGF
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB6 NIMGGKEQNSPIYISRVIPGGVADRHGGLKRGDQLLSVNGVSVEGEQHEKAVELLKAAQG
:.::::::::::::::.::::::.::::::::::::::::::::::.:::::::::::.
NP_004 NVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVSVEGEHHEKAVELLKAAKD
130 140 150 160 170 180
170 180 190 200
pF1KB6 SVKLVVRYTPRVLEEMEARFEKMRSARRRQQHQSYSSLESRG
::::::::::.:::::::::::.:.::::::.:
NP_004 SVKLVVRYTPKVLEEMEARFEKLRTARRRQQQQLLIQQQQQQQQQQTQQNHMS
190 200 210 220 230
>>XP_006723386 (OMIM: 612331) PREDICTED: protein lin-7 h (183 aa)
initn: 847 init1: 847 opt: 847 Z-score: 673.2 bits: 131.4 E(85289): 9.2e-31
Smith-Waterman score: 1114; 88.4% identity (88.4% similar) in 207 aa overlap (1-207:1-183)
10 20 30 40 50 60
pF1KB6 MAALVEPLGLERDVSRAVELLERLQRSGELPPQKLQALQRVLQSRFCSAIREVYEQLYDT
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAALVEPLGLERDVSRAVELLERLQRSGELPPQKLQALQRVLQSRFCSAIRE--------
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 LDITGSAEIRAHATAKATVAAFTASEGHAHPRVVELPKTDEGLGFNIMGGKEQNSPIYIS
::::::::::::::::::::::::::::::::::::::::::::
XP_006 ----------------ATVAAFTASEGHAHPRVVELPKTDEGLGFNIMGGKEQNSPIYIS
60 70 80 90
130 140 150 160 170 180
pF1KB6 RVIPGGVADRHGGLKRGDQLLSVNGVSVEGEQHEKAVELLKAAQGSVKLVVRYTPRVLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RVIPGGVADRHGGLKRGDQLLSVNGVSVEGEQHEKAVELLKAAQGSVKLVVRYTPRVLEE
100 110 120 130 140 150
190 200
pF1KB6 MEARFEKMRSARRRQQHQSYSSLESRG
:::::::::::::::::::::::::::
XP_006 MEARFEKMRSARRRQQHQSYSSLESRG
160 170 180
>>NP_001311352 (OMIM: 603380) protein lin-7 homolog A is (162 aa)
initn: 820 init1: 766 opt: 795 Z-score: 634.2 bits: 124.0 E(85289): 1.4e-28
Smith-Waterman score: 795; 83.8% identity (97.2% similar) in 142 aa overlap (57-198:1-142)
30 40 50 60 70 80
pF1KB6 SGELPPQKLQALQRVLQSRFCSAIREVYEQLYDTLDITGSAEIRAHATAKATVAAFTASE
...:. ..: :.::.::::::::::.:::
NP_001 MHETITVNGCPEFRARATAKATVAAFAASE
10 20 30
90 100 110 120 130 140
pF1KB6 GHAHPRVVELPKTDEGLGFNIMGGKEQNSPIYISRVIPGGVADRHGGLKRGDQLLSVNGV
::.:::::::::::::::::.::::::::::::::.::::::.:::::::::::::::::
NP_001 GHSHPRVVELPKTDEGLGFNVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGV
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB6 SVEGEQHEKAVELLKAAQGSVKLVVRYTPRVLEEMEARFEKMRSARRRQQHQSYSSLESR
:::::.:::::::::::. ::::::::::.:::::::::::.:.::::::.:
NP_001 SVEGEHHEKAVELLKAAKDSVKLVVRYTPKVLEEMEARFEKLRTARRRQQQQLLIQQQQQ
100 110 120 130 140 150
pF1KB6 G
NP_001 QQQQQTQQNHMS
160
>>XP_011537230 (OMIM: 603380) PREDICTED: protein lin-7 h (186 aa)
initn: 758 init1: 758 opt: 768 Z-score: 612.9 bits: 120.2 E(85289): 2.1e-27
Smith-Waterman score: 768; 74.5% identity (94.8% similar) in 153 aa overlap (1-151:14-166)
10 20 30 40
pF1KB6 MAAL--VEPLGLERDVSRAVELLERLQRSGELPPQKLQALQRVLQSR
::.: :.:: :.:::.::.::::.::.:::.: .:::.:..::::.
XP_011 MLKPSVTSAPTADMATLTVVQPLTLDRDVARAIELLEKLQESGEVPVHKLQSLKKVLQSE
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB6 FCSAIREVYEQLYDTLDITGSAEIRAHATAKATVAAFTASEGHAHPRVVELPKTDEGLGF
::.::::::. ...:. ..: :.::.::::::::::.:::::.::::::::::::::::
XP_011 FCTAIREVYQYMHETITVNGCPEFRARATAKATVAAFAASEGHSHPRVVELPKTDEGLGF
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB6 NIMGGKEQNSPIYISRVIPGGVADRHGGLKRGDQLLSVNGVSVEGEQHEKAVELLKAAQG
:.::::::::::::::.::::::.:::::::::::::::::..::.
XP_011 NVMGGKEQNSPIYISRIIPGGVAERHGGLKRGDQLLSVNGVALEGKLLDQTSDSHKFETV
130 140 150 160 170 180
170 180 190 200
pF1KB6 SVKLVVRYTPRVLEEMEARFEKMRSARRRQQHQSYSSLESRG
XP_011 LQNPST
>>NP_001295348 (OMIM: 612331) protein lin-7 homolog B is (137 aa)
initn: 513 init1: 476 opt: 503 Z-score: 412.2 bits: 82.6 E(85289): 3.2e-16
Smith-Waterman score: 706; 66.2% identity (66.2% similar) in 207 aa overlap (1-207:1-137)
10 20 30 40 50 60
pF1KB6 MAALVEPLGLERDVSRAVELLERLQRSGELPPQKLQALQRVLQSRFCSAIREVYEQLYDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAALVEPLGLERDVSRAVELLERLQRSGELPPQKLQALQRVLQSRFCSAIREVYEQLYDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 LDITGSAEIRAHATAKATVAAFTASEGHAHPRVVELPKTDEGLGFNIMGGKEQNSPIYIS
::::::::::::::::
NP_001 LDITGSAEIRAHATAK--------------------------------------------
70
130 140 150 160 170 180
pF1KB6 RVIPGGVADRHGGLKRGDQLLSVNGVSVEGEQHEKAVELLKAAQGSVKLVVRYTPRVLEE
::::::::::::::::::::::::::::::::::
NP_001 --------------------------SVEGEQHEKAVELLKAAQGSVKLVVRYTPRVLEE
80 90 100 110
190 200
pF1KB6 MEARFEKMRSARRRQQHQSYSSLESRG
:::::::::::::::::::::::::::
NP_001 MEARFEKMRSARRRQQHQSYSSLESRG
120 130
>>XP_016882620 (OMIM: 612331) PREDICTED: protein lin-7 h (105 aa)
initn: 335 init1: 335 opt: 335 Z-score: 285.3 bits: 58.8 E(85289): 3.7e-09
Smith-Waterman score: 335; 61.5% identity (76.0% similar) in 96 aa overlap (1-96:1-96)
10 20 30 40 50 60
pF1KB6 MAALVEPLGLERDVSRAVELLERLQRSGELPPQKLQALQRVLQSRFCSAIREVYEQLYDT
:::::::::::::::::::::::::::::::::::::::::::::::::::: ...
XP_016 MAALVEPLGLERDVSRAVELLERLQRSGELPPQKLQALQRVLQSRFCSAIREGWRSWRLP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 LDITGSAEIRAHATAKATVAAFTASEGHAHPRVVELPKTDEGLGFNIMGGKEQNSPIYIS
..: . . .. : : :: .::....
XP_016 DAAASSPRCMSSFMTRWTSPAAPRSEPMPQPRALRVSSMRRRWSC
70 80 90 100
130 140 150 160 170 180
pF1KB6 RVIPGGVADRHGGLKRGDQLLSVNGVSVEGEQHEKAVELLKAAQGSVKLVVRYTPRVLEE
>>XP_016872775 (OMIM: 603583) PREDICTED: disks large hom (757 aa)
initn: 317 init1: 187 opt: 293 Z-score: 243.4 bits: 53.9 E(85289): 8e-07
Smith-Waterman score: 293; 38.5% identity (68.9% similar) in 148 aa overlap (61-202:257-399)
40 50 60 70 80
pF1KB6 PPQKLQALQRVLQSRFCSAIREVYEQLYDTLDITGSAEIRAH-----ATAKATVAAFTAS
: . ..:. .: :: . ... :
XP_016 LCDKPASPRHYSPVECDKSFLLSAPYSHYHLGLLPDSEMTSHSQHSTATRQPSMTLQRAV
230 240 250 260 270 280
90 100 110 120 130 140
pF1KB6 EGHAHPRVVELPKTDEGLGFNIMGGKEQNSPIYISRVIPGGVADRHGGLKRGDQLLSVNG
...:: : : : . ::::::.:: :.. :..: .. :: :: : :.::::.:::::
XP_016 SLEGEPRKVVLHKGSTGLGFNIVGG-EDGEGIFVSFILAGGPADLSGELQRGDQILSVNG
290 300 310 320 330 340
150 160 170 180 190 200
pF1KB6 VSVEGEQHEKAVELLKAAQGSVKLVVRYTPRVLEEMEARFE-KMRSARRRQQHQSYSSLE
....: .::.:. ::.: .: ....: : : :::: :... :......:.::
XP_016 IDLRGASHEQAAAALKGAGQTVTIIAQYQP----EDYARFEAKIHDLREQMMNHSMSSGS
350 360 370 380 390 400
pF1KB6 SRG
XP_016 GSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEWWQARRVMLEG
410 420 430 440 450 460
>>XP_016872773 (OMIM: 603583) PREDICTED: disks large hom (801 aa)
initn: 369 init1: 187 opt: 293 Z-score: 243.2 bits: 53.9 E(85289): 8.3e-07
Smith-Waterman score: 293; 38.5% identity (68.9% similar) in 148 aa overlap (61-202:301-443)
40 50 60 70 80
pF1KB6 PPQKLQALQRVLQSRFCSAIREVYEQLYDTLDITGSAEIRAH-----ATAKATVAAFTAS
: . ..:. .: :: . ... :
XP_016 LCDKPASPRHYSPVECDKSFLLSAPYSHYHLGLLPDSEMTSHSQHSTATRQPSMTLQRAV
280 290 300 310 320 330
90 100 110 120 130 140
pF1KB6 EGHAHPRVVELPKTDEGLGFNIMGGKEQNSPIYISRVIPGGVADRHGGLKRGDQLLSVNG
...:: : : : . ::::::.:: :.. :..: .. :: :: : :.::::.:::::
XP_016 SLEGEPRKVVLHKGSTGLGFNIVGG-EDGEGIFVSFILAGGPADLSGELQRGDQILSVNG
340 350 360 370 380
150 160 170 180 190 200
pF1KB6 VSVEGEQHEKAVELLKAAQGSVKLVVRYTPRVLEEMEARFE-KMRSARRRQQHQSYSSLE
....: .::.:. ::.: .: ....: : : :::: :... :......:.::
XP_016 IDLRGASHEQAAAALKGAGQTVTIIAQYQP----EDYARFEAKIHDLREQMMNHSMSSGS
390 400 410 420 430 440
pF1KB6 SRG
XP_016 GSLRTNQKRSLYVRAMFDYDKSKDSGLPSQGLSFKYGDILHVINASDDEWWQARRVMLEG
450 460 470 480 490 500
207 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 12:07:18 2016 done: Fri Nov 4 12:07:18 2016
Total Scan time: 4.170 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]