FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6929, 207 aa 1>>>pF1KB6929 207 - 207 aa - 207 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5549+/-0.000278; mu= 13.3026+/- 0.018 mean_var=75.8608+/-15.103, 0's: 0 Z-trim(120.2): 3 B-trim: 442 in 1/54 Lambda= 0.147253 statistics sampled from 35070 (35073) to 35070 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.776), E-opt: 0.2 (0.411), width: 16 Scan time: 5.270 The best scores are: opt bits E(85289) NP_001079 (OMIM: 600950,614163) serotonin N-acetyl ( 207) 1457 317.9 7.3e-87 XP_016879748 (OMIM: 600950,614163) PREDICTED: sero ( 245) 1457 318.0 8.4e-87 NP_001160051 (OMIM: 600950,614163) serotonin N-ace ( 252) 1457 318.0 8.6e-87 >>NP_001079 (OMIM: 600950,614163) serotonin N-acetyltran (207 aa) initn: 1457 init1: 1457 opt: 1457 Z-score: 1680.5 bits: 317.9 E(85289): 7.3e-87 Smith-Waterman score: 1457; 100.0% identity (100.0% similar) in 207 aa overlap (1-207:1-207) 10 20 30 40 50 60 pF1KB6 MSTQSTHPLKPEAPRLPPGIPESPSCQRRHTLPASEFRCLTPEDAVSAFEIEREAFISVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSTQSTHPLKPEAPRLPPGIPESPSCQRRHTLPASEFRCLTPEDAVSAFEIEREAFISVL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GVCPLYLDEIRHFLTLCPELSLGWFEEGCLVAFIIGSLWDKERLMQESLTLHRSGGHIAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GVCPLYLDEIRHFLTLCPELSLGWFEEGCLVAFIIGSLWDKERLMQESLTLHRSGGHIAH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LHVLAVHRAFRQQGRGPILLWRYLHHLGSQPAVRRAALMCEDALVPFYERFSFHAVGPCA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LHVLAVHRAFRQQGRGPILLWRYLHHLGSQPAVRRAALMCEDALVPFYERFSFHAVGPCA 130 140 150 160 170 180 190 200 pF1KB6 ITVGSLTFMELHCSLRGHPFLRRNSGC ::::::::::::::::::::::::::: NP_001 ITVGSLTFMELHCSLRGHPFLRRNSGC 190 200 >>XP_016879748 (OMIM: 600950,614163) PREDICTED: serotoni (245 aa) initn: 1457 init1: 1457 opt: 1457 Z-score: 1679.4 bits: 318.0 E(85289): 8.4e-87 Smith-Waterman score: 1457; 100.0% identity (100.0% similar) in 207 aa overlap (1-207:39-245) 10 20 30 pF1KB6 MSTQSTHPLKPEAPRLPPGIPESPSCQRRH :::::::::::::::::::::::::::::: XP_016 AVLQQVLGGPPWLRRTLPKLGRPKEAPVARMSTQSTHPLKPEAPRLPPGIPESPSCQRRH 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB6 TLPASEFRCLTPEDAVSAFEIEREAFISVLGVCPLYLDEIRHFLTLCPELSLGWFEEGCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLPASEFRCLTPEDAVSAFEIEREAFISVLGVCPLYLDEIRHFLTLCPELSLGWFEEGCL 70 80 90 100 110 120 100 110 120 130 140 150 pF1KB6 VAFIIGSLWDKERLMQESLTLHRSGGHIAHLHVLAVHRAFRQQGRGPILLWRYLHHLGSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VAFIIGSLWDKERLMQESLTLHRSGGHIAHLHVLAVHRAFRQQGRGPILLWRYLHHLGSQ 130 140 150 160 170 180 160 170 180 190 200 pF1KB6 PAVRRAALMCEDALVPFYERFSFHAVGPCAITVGSLTFMELHCSLRGHPFLRRNSGC ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PAVRRAALMCEDALVPFYERFSFHAVGPCAITVGSLTFMELHCSLRGHPFLRRNSGC 190 200 210 220 230 240 >>NP_001160051 (OMIM: 600950,614163) serotonin N-acetylt (252 aa) initn: 1457 init1: 1457 opt: 1457 Z-score: 1679.2 bits: 318.0 E(85289): 8.6e-87 Smith-Waterman score: 1457; 100.0% identity (100.0% similar) in 207 aa overlap (1-207:46-252) 10 20 30 pF1KB6 MSTQSTHPLKPEAPRLPPGIPESPSCQRRH :::::::::::::::::::::::::::::: NP_001 PWRLKVLGGPPWLRRTLPKLGRPKEAPVARMSTQSTHPLKPEAPRLPPGIPESPSCQRRH 20 30 40 50 60 70 40 50 60 70 80 90 pF1KB6 TLPASEFRCLTPEDAVSAFEIEREAFISVLGVCPLYLDEIRHFLTLCPELSLGWFEEGCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLPASEFRCLTPEDAVSAFEIEREAFISVLGVCPLYLDEIRHFLTLCPELSLGWFEEGCL 80 90 100 110 120 130 100 110 120 130 140 150 pF1KB6 VAFIIGSLWDKERLMQESLTLHRSGGHIAHLHVLAVHRAFRQQGRGPILLWRYLHHLGSQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VAFIIGSLWDKERLMQESLTLHRSGGHIAHLHVLAVHRAFRQQGRGPILLWRYLHHLGSQ 140 150 160 170 180 190 160 170 180 190 200 pF1KB6 PAVRRAALMCEDALVPFYERFSFHAVGPCAITVGSLTFMELHCSLRGHPFLRRNSGC ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PAVRRAALMCEDALVPFYERFSFHAVGPCAITVGSLTFMELHCSLRGHPFLRRNSGC 200 210 220 230 240 250 207 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 12:07:45 2016 done: Fri Nov 4 12:07:45 2016 Total Scan time: 5.270 Total Display time: -0.040 Function used was FASTA [36.3.4 Apr, 2011]