FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6930, 228 aa 1>>>pF1KB6930 228 - 228 aa - 228 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6178+/-0.000768; mu= 12.5887+/- 0.046 mean_var=66.0938+/-13.167, 0's: 0 Z-trim(108.4): 22 B-trim: 0 in 0/49 Lambda= 0.157759 statistics sampled from 10160 (10178) to 10160 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.7), E-opt: 0.2 (0.313), width: 16 Scan time: 1.760 The best scores are: opt bits E(32554) CCDS549.1 CMPK1 gene_id:51727|Hs108|chr1 ( 228) 1499 349.5 1e-96 CCDS44135.1 CMPK1 gene_id:51727|Hs108|chr1 ( 179) 814 193.6 7e-50 CCDS83419.1 AK1 gene_id:203|Hs108|chr9 ( 210) 522 127.2 8.2e-30 CCDS6881.1 AK1 gene_id:203|Hs108|chr9 ( 194) 521 126.9 8.9e-30 CCDS676.1 AK5 gene_id:26289|Hs108|chr1 ( 536) 441 108.9 6.7e-24 CCDS675.1 AK5 gene_id:26289|Hs108|chr1 ( 562) 441 108.9 6.9e-24 >>CCDS549.1 CMPK1 gene_id:51727|Hs108|chr1 (228 aa) initn: 1499 init1: 1499 opt: 1499 Z-score: 1849.9 bits: 349.5 E(32554): 1e-96 Smith-Waterman score: 1499; 99.6% identity (99.6% similar) in 228 aa overlap (1-228:1-228) 10 20 30 40 50 60 pF1KB6 MLSRCRSRLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVEKYG ::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 MLSRCRSGLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVEKYG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 YTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 YTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 FLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 FLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESL 130 140 150 160 170 180 190 200 210 220 pF1KB6 EKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG :::::::::::::::::::::::::::::::::::::::::::::::: CCDS54 EKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG 190 200 210 220 >>CCDS44135.1 CMPK1 gene_id:51727|Hs108|chr1 (179 aa) initn: 814 init1: 814 opt: 814 Z-score: 1009.0 bits: 193.6 E(32554): 7e-50 Smith-Waterman score: 1079; 78.1% identity (78.1% similar) in 228 aa overlap (1-228:1-179) 10 20 30 40 50 60 pF1KB6 MLSRCRSRLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVEKYG ::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 MLSRCRSGLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVE--- 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 YTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNK :::::::::::::: CCDS44 ----------------------------------------------EMDQTMAANAQKNK 60 70 130 140 150 160 170 180 pF1KB6 FLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 FLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESL 80 90 100 110 120 130 190 200 210 220 pF1KB6 EKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG :::::::::::::::::::::::::::::::::::::::::::::::: CCDS44 EKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG 140 150 160 170 >>CCDS83419.1 AK1 gene_id:203|Hs108|chr9 (210 aa) initn: 428 init1: 203 opt: 522 Z-score: 648.7 bits: 127.2 E(32554): 8.2e-30 Smith-Waterman score: 522; 40.7% identity (74.5% similar) in 204 aa overlap (22-225:11-207) 10 20 30 40 50 60 pF1KB6 MLSRCRSRLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVEKYG :. : .: : ..::.::::.:::::: .::.::: CCDS83 MGCCSSSDPRREDDLRAREKLKKTKIIFVVGGPGSGKGTQCEKIVQKYG 10 20 30 40 70 80 90 100 110 120 pF1KB6 YTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNK :::::.:.:::.: .. : :. . . ...:..::.: ....:. : . .:..:. CCDS83 YTHLSTGDLLRSEVSS-GSARGKKLSEIMEKGQLVPLETVLDMLRDAM--VAKVNTSKG- 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB6 FLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESL :::::.::. .. . ... . :. ...:. : . : .: :.::..::: :::.:.. CCDS83 FLIDGYPREVQQGEEFERRI-GQP--TLLLYVDAGPETMTQRLLKRGETSGRVDDNEETI 110 120 130 140 150 160 190 200 210 220 pF1KB6 EKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG .::..:: ..:.:.: .::. : :.:..: ::: ::..: .: CCDS83 KKRLETYYKATEPVIAFYEKRGIVRKVNAEGSVDSVFSQVCTHLDALK 170 180 190 200 210 >>CCDS6881.1 AK1 gene_id:203|Hs108|chr9 (194 aa) initn: 428 init1: 203 opt: 521 Z-score: 648.0 bits: 126.9 E(32554): 8.9e-30 Smith-Waterman score: 521; 41.5% identity (76.4% similar) in 195 aa overlap (31-225:4-191) 10 20 30 40 50 60 pF1KB6 MLSRCRSRLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVEKYG .: : ..::.::::.:::::: .::.::: CCDS68 MEEKLKKTKIIFVVGGPGSGKGTQCEKIVQKYG 10 20 30 70 80 90 100 110 120 pF1KB6 YTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNK :::::.:.:::.: .. : :. . . ...:..::.: ....:. : . .:..:. CCDS68 YTHLSTGDLLRSEVSS-GSARGKKLSEIMEKGQLVPLETVLDMLRDAM--VAKVNTSKG- 40 50 60 70 80 130 140 150 160 170 180 pF1KB6 FLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESL :::::.::. .. . ... . :. ...:. : . : .: :.::..::: :::.:.. CCDS68 FLIDGYPREVQQGEEFERRI-GQP--TLLLYVDAGPETMTQRLLKRGETSGRVDDNEETI 90 100 110 120 130 140 190 200 210 220 pF1KB6 EKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG .::..:: ..:.:.: .::. : :.:..: ::: ::..: .: CCDS68 KKRLETYYKATEPVIAFYEKRGIVRKVNAEGSVDSVFSQVCTHLDALK 150 160 170 180 190 >>CCDS676.1 AK5 gene_id:26289|Hs108|chr1 (536 aa) initn: 484 init1: 187 opt: 441 Z-score: 542.6 bits: 108.9 E(32554): 6.7e-24 Smith-Waterman score: 441; 36.6% identity (71.1% similar) in 194 aa overlap (32-225:347-533) 10 20 30 40 50 60 pF1KB6 LSRCRSRLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVEKYGY : : ..:..::::.:::::: ..:::::. CCDS67 IIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLRKCKIIFIIGGPGSGKGTQCEKLVEKYGF 320 330 340 350 360 370 70 80 90 100 110 120 pF1KB6 THLSAGELLRDERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNKF ::::.:::::.: . .:. ..::. ...: .:: :.. :::. : .:. .. : CCDS67 THLSTGELLREELAS-ESERSKLIRDIMERGDLVPSGIVLELLKEAM---VASLGDTRGF 380 390 400 410 420 430 130 140 150 160 170 180 pF1KB6 LIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESLE ::::.::. . . ... . .: ..:. .::. . .: :.:..:: ::. ... CCDS67 LIDGYPREVKQGEEFGRRI---GDPQLVICMDCSADTMTNRLLQRSRSSLPVDDTTKTIA 440 450 460 470 480 190 200 210 220 pF1KB6 KRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG ::...: ... :.: :: ...::.: . ..:: .. .: CCDS67 KRLEAYYRASIPVIAYYETKTQLHKINAEGTPEDVFLQLCTAIDSIF 490 500 510 520 530 >-- initn: 350 init1: 169 opt: 410 Z-score: 504.5 bits: 101.8 E(32554): 8.9e-22 Smith-Waterman score: 410; 34.2% identity (67.8% similar) in 199 aa overlap (30-227:101-292) 10 20 30 40 50 pF1KB6 MLSRCRSRLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVEKY : .: ...:.::::.::::: .:.:.: CCDS67 RLPPIHQFSIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERY 80 90 100 110 120 130 60 70 80 90 100 110 pF1KB6 GYTHLSAGELLRDERKNPDSQYG-ELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQK :. ..:.::::: . .. .:. :: : : :...: : ::. .:... : .. CCDS67 GFQYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQETTITEIKQKLMQI----PDE 140 150 160 170 180 120 130 140 150 160 170 pF1KB6 NKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRE . ..:::::: : :. . : ..:.:. : :. :: :.:....:: ::: . CCDS67 EGIVIDGFPR--DVAQALS-FEDQICTPDLVVFLACANQRLKERLLKRAEQQGRPDDNVK 190 200 210 220 230 240 180 190 200 210 220 pF1KB6 SLEKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG . ..:.... :.. :.. ..: : . .::... :::: .. . :.. CCDS67 ATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDNKLFPNKEAAAGS 250 260 270 280 290 300 CCDS67 SDLDPSMILDTGEIIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLRKCKIIFIIGGPGSGK 310 320 330 340 350 360 >>CCDS675.1 AK5 gene_id:26289|Hs108|chr1 (562 aa) initn: 484 init1: 187 opt: 441 Z-score: 542.3 bits: 108.9 E(32554): 6.9e-24 Smith-Waterman score: 441; 36.6% identity (71.1% similar) in 194 aa overlap (32-225:373-559) 10 20 30 40 50 60 pF1KB6 LSRCRSRLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVEKYGY : : ..:..::::.:::::: ..:::::. CCDS67 IIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLRKCKIIFIIGGPGSGKGTQCEKLVEKYGF 350 360 370 380 390 400 70 80 90 100 110 120 pF1KB6 THLSAGELLRDERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNKF ::::.:::::.: . .:. ..::. ...: .:: :.. :::. : .:. .. : CCDS67 THLSTGELLREELAS-ESERSKLIRDIMERGDLVPSGIVLELLKEAM---VASLGDTRGF 410 420 430 440 450 130 140 150 160 170 180 pF1KB6 LIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESLE ::::.::. . . ... . .: ..:. .::. . .: :.:..:: ::. ... CCDS67 LIDGYPREVKQGEEFGRRI---GDPQLVICMDCSADTMTNRLLQRSRSSLPVDDTTKTIA 460 470 480 490 500 510 190 200 210 220 pF1KB6 KRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG ::...: ... :.: :: ...::.: . ..:: .. .: CCDS67 KRLEAYYRASIPVIAYYETKTQLHKINAEGTPEDVFLQLCTAIDSIF 520 530 540 550 560 >-- initn: 350 init1: 169 opt: 410 Z-score: 504.1 bits: 101.8 E(32554): 9.2e-22 Smith-Waterman score: 410; 34.2% identity (67.8% similar) in 199 aa overlap (30-227:127-318) 10 20 30 40 50 pF1KB6 MLSRCRSRLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVEKY : .: ...:.::::.::::: .:.:.: CCDS67 RLPPIHQFSIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERY 100 110 120 130 140 150 60 70 80 90 100 110 pF1KB6 GYTHLSAGELLRDERKNPDSQYG-ELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQK :. ..:.::::: . .. .:. :: : : :...: : ::. .:... : .. CCDS67 GFQYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQETTITEIKQKLMQI----PDE 160 170 180 190 200 210 120 130 140 150 160 170 pF1KB6 NKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRE . ..:::::: : :. . : ..:.:. : :. :: :.:....:: ::: . CCDS67 EGIVIDGFPR--DVAQALS-FEDQICTPDLVVFLACANQRLKERLLKRAEQQGRPDDNVK 220 230 240 250 260 180 190 200 210 220 pF1KB6 SLEKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG . ..:.... :.. :.. ..: : . .::... :::: .. . :.. CCDS67 ATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDNKLFPNKEAAAGS 270 280 290 300 310 320 CCDS67 SDLDPSMILDTGEIIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLRKCKIIFIIGGPGSGK 330 340 350 360 370 380 228 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 12:05:03 2016 done: Fri Nov 4 12:05:03 2016 Total Scan time: 1.760 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]