FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6930, 228 aa 1>>>pF1KB6930 228 - 228 aa - 228 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1823+/-0.000344; mu= 15.2260+/- 0.021 mean_var=65.7883+/-13.258, 0's: 0 Z-trim(115.2): 61 B-trim: 220 in 1/49 Lambda= 0.158125 statistics sampled from 25363 (25424) to 25363 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.681), E-opt: 0.2 (0.298), width: 16 Scan time: 4.920 The best scores are: opt bits E(85289) NP_057392 (OMIM: 191710) UMP-CMP kinase isoform a ( 228) 1499 350.3 1.6e-96 NP_001129612 (OMIM: 191710) UMP-CMP kinase isoform ( 179) 814 194.0 1.4e-49 NP_001305051 (OMIM: 103000,612631) adenylate kinas ( 210) 522 127.4 1.8e-29 NP_001305050 (OMIM: 103000,612631) adenylate kinas ( 194) 521 127.2 2e-29 XP_016869916 (OMIM: 103000,612631) PREDICTED: aden ( 194) 521 127.2 2e-29 NP_000467 (OMIM: 103000,612631) adenylate kinase i ( 194) 521 127.2 2e-29 XP_016869917 (OMIM: 103000,612631) PREDICTED: aden ( 194) 521 127.2 2e-29 XP_016856500 (OMIM: 608009) PREDICTED: adenylate k ( 512) 441 109.2 1.4e-23 XP_016856499 (OMIM: 608009) PREDICTED: adenylate k ( 512) 441 109.2 1.4e-23 XP_016856498 (OMIM: 608009) PREDICTED: adenylate k ( 536) 441 109.2 1.4e-23 NP_036225 (OMIM: 608009) adenylate kinase isoenzym ( 536) 441 109.2 1.4e-23 XP_016856497 (OMIM: 608009) PREDICTED: adenylate k ( 536) 441 109.2 1.4e-23 XP_006710635 (OMIM: 608009) PREDICTED: adenylate k ( 536) 441 109.2 1.4e-23 XP_005270796 (OMIM: 608009) PREDICTED: adenylate k ( 538) 441 109.2 1.4e-23 NP_777283 (OMIM: 608009) adenylate kinase isoenzym ( 562) 441 109.2 1.5e-23 XP_016856501 (OMIM: 608009) PREDICTED: adenylate k ( 389) 410 102.0 1.5e-21 NP_037542 (OMIM: 103030) adenylate kinase 4, mitoc ( 223) 233 61.5 1.3e-09 NP_001005353 (OMIM: 103030) adenylate kinase 4, mi ( 223) 233 61.5 1.3e-09 NP_982289 (OMIM: 103030) adenylate kinase 4, mitoc ( 223) 233 61.5 1.3e-09 NP_001306072 (OMIM: 103020,267500) adenylate kinas ( 133) 215 57.3 1.5e-08 NP_057366 (OMIM: 609290) GTP:AMP phosphotransferas ( 227) 211 56.5 4.4e-08 NP_001304887 (OMIM: 615365) adenylate kinase 8 iso ( 275) 157 44.2 0.00026 NP_001304888 (OMIM: 615365) adenylate kinase 8 iso ( 307) 157 44.2 0.00029 XP_016869797 (OMIM: 615365) PREDICTED: adenylate k ( 307) 157 44.2 0.00029 XP_011516580 (OMIM: 615365) PREDICTED: adenylate k ( 405) 157 44.3 0.00036 XP_006717028 (OMIM: 615365) PREDICTED: adenylate k ( 407) 157 44.3 0.00036 NP_001138600 (OMIM: 615358) adenylate kinase 9 iso (1911) 165 46.5 0.00036 XP_006715439 (OMIM: 615358) PREDICTED: adenylate k (1983) 165 46.6 0.00037 NP_689785 (OMIM: 615365) adenylate kinase 8 isofor ( 479) 157 44.4 0.00041 XP_005272226 (OMIM: 615365) PREDICTED: adenylate k ( 491) 157 44.4 0.00042 NP_001306068 (OMIM: 103020,267500) adenylate kinas ( 184) 145 41.4 0.0013 NP_001306071 (OMIM: 103020,267500) adenylate kinas ( 190) 145 41.4 0.0013 NP_001306069 (OMIM: 103020,267500) adenylate kinas ( 191) 145 41.4 0.0013 NP_001186128 (OMIM: 103020,267500) adenylate kinas ( 224) 145 41.4 0.0015 NP_001306070 (OMIM: 103020,267500) adenylate kinas ( 232) 145 41.4 0.0015 NP_037543 (OMIM: 103020,267500) adenylate kinase 2 ( 232) 145 41.4 0.0015 NP_001616 (OMIM: 103020,267500) adenylate kinase 2 ( 239) 145 41.4 0.0016 >>NP_057392 (OMIM: 191710) UMP-CMP kinase isoform a [Hom (228 aa) initn: 1499 init1: 1499 opt: 1499 Z-score: 1854.1 bits: 350.3 E(85289): 1.6e-96 Smith-Waterman score: 1499; 99.6% identity (99.6% similar) in 228 aa overlap (1-228:1-228) 10 20 30 40 50 60 pF1KB6 MLSRCRSRLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVEKYG ::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MLSRCRSGLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVEKYG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 YTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 YTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 FLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 FLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESL 130 140 150 160 170 180 190 200 210 220 pF1KB6 EKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG :::::::::::::::::::::::::::::::::::::::::::::::: NP_057 EKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG 190 200 210 220 >>NP_001129612 (OMIM: 191710) UMP-CMP kinase isoform b [ (179 aa) initn: 814 init1: 814 opt: 814 Z-score: 1011.1 bits: 194.0 E(85289): 1.4e-49 Smith-Waterman score: 1079; 78.1% identity (78.1% similar) in 228 aa overlap (1-228:1-179) 10 20 30 40 50 60 pF1KB6 MLSRCRSRLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVEKYG ::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MLSRCRSGLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVE--- 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 YTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNK :::::::::::::: NP_001 ----------------------------------------------EMDQTMAANAQKNK 60 70 130 140 150 160 170 180 pF1KB6 FLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESL 80 90 100 110 120 130 190 200 210 220 pF1KB6 EKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG 140 150 160 170 >>NP_001305051 (OMIM: 103000,612631) adenylate kinase is (210 aa) initn: 428 init1: 203 opt: 522 Z-score: 650.1 bits: 127.4 E(85289): 1.8e-29 Smith-Waterman score: 522; 40.7% identity (74.5% similar) in 204 aa overlap (22-225:11-207) 10 20 30 40 50 60 pF1KB6 MLSRCRSRLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVEKYG :. : .: : ..::.::::.:::::: .::.::: NP_001 MGCCSSSDPRREDDLRAREKLKKTKIIFVVGGPGSGKGTQCEKIVQKYG 10 20 30 40 70 80 90 100 110 120 pF1KB6 YTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNK :::::.:.:::.: .. : :. . . ...:..::.: ....:. : . .:..:. NP_001 YTHLSTGDLLRSEVSS-GSARGKKLSEIMEKGQLVPLETVLDMLRDAM--VAKVNTSKG- 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB6 FLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESL :::::.::. .. . ... . :. ...:. : . : .: :.::..::: :::.:.. NP_001 FLIDGYPREVQQGEEFERRI-GQP--TLLLYVDAGPETMTQRLLKRGETSGRVDDNEETI 110 120 130 140 150 160 190 200 210 220 pF1KB6 EKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG .::..:: ..:.:.: .::. : :.:..: ::: ::..: .: NP_001 KKRLETYYKATEPVIAFYEKRGIVRKVNAEGSVDSVFSQVCTHLDALK 170 180 190 200 210 >>NP_001305050 (OMIM: 103000,612631) adenylate kinase is (194 aa) initn: 428 init1: 203 opt: 521 Z-score: 649.3 bits: 127.2 E(85289): 2e-29 Smith-Waterman score: 521; 41.5% identity (76.4% similar) in 195 aa overlap (31-225:4-191) 10 20 30 40 50 60 pF1KB6 MLSRCRSRLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVEKYG .: : ..::.::::.:::::: .::.::: NP_001 MEEKLKKTKIIFVVGGPGSGKGTQCEKIVQKYG 10 20 30 70 80 90 100 110 120 pF1KB6 YTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNK :::::.:.:::.: .. : :. . . ...:..::.: ....:. : . .:..:. NP_001 YTHLSTGDLLRSEVSS-GSARGKKLSEIMEKGQLVPLETVLDMLRDAM--VAKVNTSKG- 40 50 60 70 80 130 140 150 160 170 180 pF1KB6 FLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESL :::::.::. .. . ... . :. ...:. : . : .: :.::..::: :::.:.. NP_001 FLIDGYPREVQQGEEFERRI-GQP--TLLLYVDAGPETMTQRLLKRGETSGRVDDNEETI 90 100 110 120 130 140 190 200 210 220 pF1KB6 EKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG .::..:: ..:.:.: .::. : :.:..: ::: ::..: .: NP_001 KKRLETYYKATEPVIAFYEKRGIVRKVNAEGSVDSVFSQVCTHLDALK 150 160 170 180 190 >>XP_016869916 (OMIM: 103000,612631) PREDICTED: adenylat (194 aa) initn: 428 init1: 203 opt: 521 Z-score: 649.3 bits: 127.2 E(85289): 2e-29 Smith-Waterman score: 521; 41.5% identity (76.4% similar) in 195 aa overlap (31-225:4-191) 10 20 30 40 50 60 pF1KB6 MLSRCRSRLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVEKYG .: : ..::.::::.:::::: .::.::: XP_016 MEEKLKKTKIIFVVGGPGSGKGTQCEKIVQKYG 10 20 30 70 80 90 100 110 120 pF1KB6 YTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNK :::::.:.:::.: .. : :. . . ...:..::.: ....:. : . .:..:. XP_016 YTHLSTGDLLRSEVSS-GSARGKKLSEIMEKGQLVPLETVLDMLRDAM--VAKVNTSKG- 40 50 60 70 80 130 140 150 160 170 180 pF1KB6 FLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESL :::::.::. .. . ... . :. ...:. : . : .: :.::..::: :::.:.. XP_016 FLIDGYPREVQQGEEFERRI-GQP--TLLLYVDAGPETMTQRLLKRGETSGRVDDNEETI 90 100 110 120 130 140 190 200 210 220 pF1KB6 EKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG .::..:: ..:.:.: .::. : :.:..: ::: ::..: .: XP_016 KKRLETYYKATEPVIAFYEKRGIVRKVNAEGSVDSVFSQVCTHLDALK 150 160 170 180 190 >>NP_000467 (OMIM: 103000,612631) adenylate kinase isoen (194 aa) initn: 428 init1: 203 opt: 521 Z-score: 649.3 bits: 127.2 E(85289): 2e-29 Smith-Waterman score: 521; 41.5% identity (76.4% similar) in 195 aa overlap (31-225:4-191) 10 20 30 40 50 60 pF1KB6 MLSRCRSRLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVEKYG .: : ..::.::::.:::::: .::.::: NP_000 MEEKLKKTKIIFVVGGPGSGKGTQCEKIVQKYG 10 20 30 70 80 90 100 110 120 pF1KB6 YTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNK :::::.:.:::.: .. : :. . . ...:..::.: ....:. : . .:..:. NP_000 YTHLSTGDLLRSEVSS-GSARGKKLSEIMEKGQLVPLETVLDMLRDAM--VAKVNTSKG- 40 50 60 70 80 130 140 150 160 170 180 pF1KB6 FLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESL :::::.::. .. . ... . :. ...:. : . : .: :.::..::: :::.:.. NP_000 FLIDGYPREVQQGEEFERRI-GQP--TLLLYVDAGPETMTQRLLKRGETSGRVDDNEETI 90 100 110 120 130 140 190 200 210 220 pF1KB6 EKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG .::..:: ..:.:.: .::. : :.:..: ::: ::..: .: NP_000 KKRLETYYKATEPVIAFYEKRGIVRKVNAEGSVDSVFSQVCTHLDALK 150 160 170 180 190 >>XP_016869917 (OMIM: 103000,612631) PREDICTED: adenylat (194 aa) initn: 428 init1: 203 opt: 521 Z-score: 649.3 bits: 127.2 E(85289): 2e-29 Smith-Waterman score: 521; 41.5% identity (76.4% similar) in 195 aa overlap (31-225:4-191) 10 20 30 40 50 60 pF1KB6 MLSRCRSRLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVEKYG .: : ..::.::::.:::::: .::.::: XP_016 MEEKLKKTKIIFVVGGPGSGKGTQCEKIVQKYG 10 20 30 70 80 90 100 110 120 pF1KB6 YTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNK :::::.:.:::.: .. : :. . . ...:..::.: ....:. : . .:..:. XP_016 YTHLSTGDLLRSEVSS-GSARGKKLSEIMEKGQLVPLETVLDMLRDAM--VAKVNTSKG- 40 50 60 70 80 130 140 150 160 170 180 pF1KB6 FLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESL :::::.::. .. . ... . :. ...:. : . : .: :.::..::: :::.:.. XP_016 FLIDGYPREVQQGEEFERRI-GQP--TLLLYVDAGPETMTQRLLKRGETSGRVDDNEETI 90 100 110 120 130 140 190 200 210 220 pF1KB6 EKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG .::..:: ..:.:.: .::. : :.:..: ::: ::..: .: XP_016 KKRLETYYKATEPVIAFYEKRGIVRKVNAEGSVDSVFSQVCTHLDALK 150 160 170 180 190 >>XP_016856500 (OMIM: 608009) PREDICTED: adenylate kinas (512 aa) initn: 484 init1: 187 opt: 441 Z-score: 544.5 bits: 109.2 E(85289): 1.4e-23 Smith-Waterman score: 441; 36.6% identity (71.1% similar) in 194 aa overlap (32-225:323-509) 10 20 30 40 50 60 pF1KB6 LSRCRSRLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVEKYGY : : ..:..::::.:::::: ..:::::. XP_016 IIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLRKCKIIFIIGGPGSGKGTQCEKLVEKYGF 300 310 320 330 340 350 70 80 90 100 110 120 pF1KB6 THLSAGELLRDERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNKF ::::.:::::.: . .:. ..::. ...: .:: :.. :::. : .:. .. : XP_016 THLSTGELLREELAS-ESERSKLIRDIMERGDLVPSGIVLELLKEAM---VASLGDTRGF 360 370 380 390 400 130 140 150 160 170 180 pF1KB6 LIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESLE ::::.::. . . ... . .: ..:. .::. . .: :.:..:: ::. ... XP_016 LIDGYPREVKQGEEFGRRI---GDPQLVICMDCSADTMTNRLLQRSRSSLPVDDTTKTIA 410 420 430 440 450 460 190 200 210 220 pF1KB6 KRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG ::...: ... :.: :: ...::.: . ..:: .. .: XP_016 KRLEAYYRASIPVIAYYETKTQLHKINAEGTPEDVFLQLCTAIDSIF 470 480 490 500 510 >-- initn: 350 init1: 169 opt: 410 Z-score: 506.3 bits: 102.1 E(85289): 1.8e-21 Smith-Waterman score: 410; 34.2% identity (67.8% similar) in 199 aa overlap (30-227:77-268) 10 20 30 40 50 pF1KB6 MLSRCRSRLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVEKY : .: ...:.::::.::::: .:.:.: XP_016 GQSRRSFLRNESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERY 50 60 70 80 90 100 60 70 80 90 100 110 pF1KB6 GYTHLSAGELLRDERKNPDSQYG-ELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQK :. ..:.::::: . .. .:. :: : : :...: : ::. .:... : .. XP_016 GFQYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQETTITEIKQKLMQI----PDE 110 120 130 140 150 160 120 130 140 150 160 170 pF1KB6 NKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRE . ..:::::: : :. . : ..:.:. : :. :: :.:....:: ::: . XP_016 EGIVIDGFPR--DVAQALS-FEDQICTPDLVVFLACANQRLKERLLKRAEQQGRPDDNVK 170 180 190 200 210 180 190 200 210 220 pF1KB6 SLEKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG . ..:.... :.. :.. ..: : . .::... :::: .. . :.. XP_016 ATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDNKLFPNKEAAAGS 220 230 240 250 260 270 XP_016 SDLDPSMILDTGEIIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLRKCKIIFIIGGPGSGK 280 290 300 310 320 330 >>XP_016856499 (OMIM: 608009) PREDICTED: adenylate kinas (512 aa) initn: 484 init1: 187 opt: 441 Z-score: 544.5 bits: 109.2 E(85289): 1.4e-23 Smith-Waterman score: 441; 36.6% identity (71.1% similar) in 194 aa overlap (32-225:323-509) 10 20 30 40 50 60 pF1KB6 LSRCRSRLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVEKYGY : : ..:..::::.:::::: ..:::::. XP_016 IIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLRKCKIIFIIGGPGSGKGTQCEKLVEKYGF 300 310 320 330 340 350 70 80 90 100 110 120 pF1KB6 THLSAGELLRDERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNKF ::::.:::::.: . .:. ..::. ...: .:: :.. :::. : .:. .. : XP_016 THLSTGELLREELAS-ESERSKLIRDIMERGDLVPSGIVLELLKEAM---VASLGDTRGF 360 370 380 390 400 130 140 150 160 170 180 pF1KB6 LIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESLE ::::.::. . . ... . .: ..:. .::. . .: :.:..:: ::. ... XP_016 LIDGYPREVKQGEEFGRRI---GDPQLVICMDCSADTMTNRLLQRSRSSLPVDDTTKTIA 410 420 430 440 450 460 190 200 210 220 pF1KB6 KRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG ::...: ... :.: :: ...::.: . ..:: .. .: XP_016 KRLEAYYRASIPVIAYYETKTQLHKINAEGTPEDVFLQLCTAIDSIF 470 480 490 500 510 >-- initn: 350 init1: 169 opt: 410 Z-score: 506.3 bits: 102.1 E(85289): 1.8e-21 Smith-Waterman score: 410; 34.2% identity (67.8% similar) in 199 aa overlap (30-227:77-268) 10 20 30 40 50 pF1KB6 MLSRCRSRLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVEKY : .: ...:.::::.::::: .:.:.: XP_016 GQSRRSFLRNESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERY 50 60 70 80 90 100 60 70 80 90 100 110 pF1KB6 GYTHLSAGELLRDERKNPDSQYG-ELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQK :. ..:.::::: . .. .:. :: : : :...: : ::. .:... : .. XP_016 GFQYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQETTITEIKQKLMQI----PDE 110 120 130 140 150 160 120 130 140 150 160 170 pF1KB6 NKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRE . ..:::::: : :. . : ..:.:. : :. :: :.:....:: ::: . XP_016 EGIVIDGFPR--DVAQALS-FEDQICTPDLVVFLACANQRLKERLLKRAEQQGRPDDNVK 170 180 190 200 210 180 190 200 210 220 pF1KB6 SLEKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG . ..:.... :.. :.. ..: : . .::... :::: .. . :.. XP_016 ATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDNKLFPNKEAAAGS 220 230 240 250 260 270 XP_016 SDLDPSMILDTGEIIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLRKCKIIFIIGGPGSGK 280 290 300 310 320 330 >>XP_016856498 (OMIM: 608009) PREDICTED: adenylate kinas (536 aa) initn: 484 init1: 187 opt: 441 Z-score: 544.2 bits: 109.2 E(85289): 1.4e-23 Smith-Waterman score: 441; 36.6% identity (71.1% similar) in 194 aa overlap (32-225:347-533) 10 20 30 40 50 60 pF1KB6 LSRCRSRLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVEKYGY : : ..:..::::.:::::: ..:::::. XP_016 IIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLRKCKIIFIIGGPGSGKGTQCEKLVEKYGF 320 330 340 350 360 370 70 80 90 100 110 120 pF1KB6 THLSAGELLRDERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNKF ::::.:::::.: . .:. ..::. ...: .:: :.. :::. : .:. .. : XP_016 THLSTGELLREELAS-ESERSKLIRDIMERGDLVPSGIVLELLKEAM---VASLGDTRGF 380 390 400 410 420 430 130 140 150 160 170 180 pF1KB6 LIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESLE ::::.::. . . ... . .: ..:. .::. . .: :.:..:: ::. ... XP_016 LIDGYPREVKQGEEFGRRI---GDPQLVICMDCSADTMTNRLLQRSRSSLPVDDTTKTIA 440 450 460 470 480 190 200 210 220 pF1KB6 KRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG ::...: ... :.: :: ...::.: . ..:: .. .: XP_016 KRLEAYYRASIPVIAYYETKTQLHKINAEGTPEDVFLQLCTAIDSIF 490 500 510 520 530 >-- initn: 350 init1: 169 opt: 410 Z-score: 506.0 bits: 102.1 E(85289): 1.9e-21 Smith-Waterman score: 410; 34.2% identity (67.8% similar) in 199 aa overlap (30-227:101-292) 10 20 30 40 50 pF1KB6 MLSRCRSRLLHVLGLSFLLQTRRPILLCSPRLMKPLVVFVLGGPGAGKGTQCARIVEKY : .: ...:.::::.::::: .:.:.: XP_016 RLPPIHQFSIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERY 80 90 100 110 120 130 60 70 80 90 100 110 pF1KB6 GYTHLSAGELLRDERKNPDSQYG-ELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQK :. ..:.::::: . .. .:. :: : : :...: : ::. .:... : .. XP_016 GFQYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQETTITEIKQKLMQI----PDE 140 150 160 170 180 120 130 140 150 160 170 pF1KB6 NKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRE . ..:::::: : :. . : ..:.:. : :. :: :.:....:: ::: . XP_016 EGIVIDGFPR--DVAQALS-FEDQICTPDLVVFLACANQRLKERLLKRAEQQGRPDDNVK 190 200 210 220 230 240 180 190 200 210 220 pF1KB6 SLEKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG . ..:.... :.. :.. ..: : . .::... :::: .. . :.. XP_016 ATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDNKLFPNKEAAAGS 250 260 270 280 290 300 XP_016 SDLDPSMILDTGEIIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLRKCKIIFIIGGPGSGK 310 320 330 340 350 360 228 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 12:05:03 2016 done: Fri Nov 4 12:05:04 2016 Total Scan time: 4.920 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]