FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6932, 228 aa 1>>>pF1KB6932 228 - 228 aa - 228 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6028+/-0.000788; mu= 11.7757+/- 0.047 mean_var=60.3722+/-12.091, 0's: 0 Z-trim(106.7): 20 B-trim: 41 in 1/53 Lambda= 0.165065 statistics sampled from 9105 (9113) to 9105 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.679), E-opt: 0.2 (0.28), width: 16 Scan time: 1.410 The best scores are: opt bits E(32554) CCDS2388.1 RPE gene_id:6120|Hs108|chr2 ( 228) 1553 378.1 2.5e-105 CCDS65929.1 RPEL1 gene_id:729020|Hs108|chr10 ( 228) 1488 362.6 1.2e-100 CCDS82567.1 RPE gene_id:6120|Hs108|chr2 ( 225) 1310 320.2 6.6e-88 CCDS82568.1 RPE gene_id:6120|Hs108|chr2 ( 191) 1303 318.6 1.8e-87 CCDS63107.1 RPE gene_id:6120|Hs108|chr2 ( 199) 1092 268.3 2.5e-72 CCDS63108.1 RPE gene_id:6120|Hs108|chr2 ( 160) 1081 265.7 1.3e-71 CCDS42810.1 RPE gene_id:6120|Hs108|chr2 ( 178) 773 192.3 1.7e-49 >>CCDS2388.1 RPE gene_id:6120|Hs108|chr2 (228 aa) initn: 1553 init1: 1553 opt: 1553 Z-score: 2004.3 bits: 378.1 E(32554): 2.5e-105 Smith-Waterman score: 1553; 100.0% identity (100.0% similar) in 228 aa overlap (1-228:1-228) 10 20 30 40 50 60 pF1KB6 MASGCKIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 MASGCKIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LGQDPFFDMHMMVSKPEQWVKPMAVAGANQYTFHLEATENPGALIKDIRENGMKVGLAIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 LGQDPFFDMHMMVSKPEQWVKPMAVAGANQYTFHLEATENPGALIKDIRENGMKVGLAIK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 PGTSVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKVHWLRTQFPSLDIEVDGGVGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 PGTSVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKVHWLRTQFPSLDIEVDGGVGP 130 140 150 160 170 180 190 200 210 220 pF1KB6 DTVHKCAEAGANMIVSGSAIMRSEDPRSVINLLRNVCSEAAQKRSLDR :::::::::::::::::::::::::::::::::::::::::::::::: CCDS23 DTVHKCAEAGANMIVSGSAIMRSEDPRSVINLLRNVCSEAAQKRSLDR 190 200 210 220 >>CCDS65929.1 RPEL1 gene_id:729020|Hs108|chr10 (228 aa) initn: 1488 init1: 1488 opt: 1488 Z-score: 1920.7 bits: 362.6 E(32554): 1.2e-100 Smith-Waterman score: 1488; 96.1% identity (97.8% similar) in 228 aa overlap (1-228:1-228) 10 20 30 40 50 60 pF1KB6 MASGCKIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQ :::::::::::::::::::::.::.::::::::::::::::::::::::::::::::::: CCDS65 MASGCKIGPSILNSDLANLGAKCLQMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LGQDPFFDMHMMVSKPEQWVKPMAVAGANQYTFHLEATENPGALIKDIRENGMKVGLAIK :::::::::::::::::::::::::: :::::::::::::::.::::::::::::::::: CCDS65 LGQDPFFDMHMMVSKPEQWVKPMAVAEANQYTFHLEATENPGTLIKDIRENGMKVGLAIK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 PGTSVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKVHWLRTQFPSLDIEVDGGVGP :::::::::::::::::::::::::::: :::::::::::::::::::::::: ::::: CCDS65 PGTSVEYLAPWANQIDMALVMTVEPGFGEQKFMEDMMPKVHWLRTQFPSLDIEGDGGVGS 130 140 150 160 170 180 190 200 210 220 pF1KB6 DTVHKCAEAGANMIVSGSAIMRSEDPRSVINLLRNVCSEAAQKRSLDR ::::::::::::: :::::::::::::::::::::.:::::::::::: CCDS65 DTVHKCAEAGANMTVSGSAIMRSEDPRSVINLLRNICSEAAQKRSLDR 190 200 210 220 >>CCDS82567.1 RPE gene_id:6120|Hs108|chr2 (225 aa) initn: 1332 init1: 1310 opt: 1310 Z-score: 1691.7 bits: 320.2 E(32554): 6.6e-88 Smith-Waterman score: 1310; 99.5% identity (99.5% similar) in 190 aa overlap (1-190:1-190) 10 20 30 40 50 60 pF1KB6 MASGCKIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 MASGCKIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LGQDPFFDMHMMVSKPEQWVKPMAVAGANQYTFHLEATENPGALIKDIRENGMKVGLAIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 LGQDPFFDMHMMVSKPEQWVKPMAVAGANQYTFHLEATENPGALIKDIRENGMKVGLAIK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 PGTSVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKVHWLRTQFPSLDIEVDGGVGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 PGTSVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKVHWLRTQFPSLDIEVDGGVGP 130 140 150 160 170 180 190 200 210 220 pF1KB6 DTVHKCAEAGANMIVSGSAIMRSEDPRSVINLLRNVCSEAAQKRSLDR :::::::: : CCDS82 DTVHKCAEIGVQWRDLCSLQSLPAGFKRFSCLSLLSSWDYRQELT 190 200 210 220 >>CCDS82568.1 RPE gene_id:6120|Hs108|chr2 (191 aa) initn: 1303 init1: 1303 opt: 1303 Z-score: 1683.9 bits: 318.6 E(32554): 1.8e-87 Smith-Waterman score: 1303; 100.0% identity (100.0% similar) in 188 aa overlap (1-188:1-188) 10 20 30 40 50 60 pF1KB6 MASGCKIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 MASGCKIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LGQDPFFDMHMMVSKPEQWVKPMAVAGANQYTFHLEATENPGALIKDIRENGMKVGLAIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 LGQDPFFDMHMMVSKPEQWVKPMAVAGANQYTFHLEATENPGALIKDIRENGMKVGLAIK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 PGTSVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKVHWLRTQFPSLDIEVDGGVGP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS82 PGTSVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKVHWLRTQFPSLDIEVDGGVGP 130 140 150 160 170 180 190 200 210 220 pF1KB6 DTVHKCAEAGANMIVSGSAIMRSEDPRSVINLLRNVCSEAAQKRSLDR :::::::: CCDS82 DTVHKCAEELT 190 >>CCDS63107.1 RPE gene_id:6120|Hs108|chr2 (199 aa) initn: 1092 init1: 1092 opt: 1092 Z-score: 1412.0 bits: 268.3 E(32554): 2.5e-72 Smith-Waterman score: 1274; 87.3% identity (87.3% similar) in 228 aa overlap (1-228:1-199) 10 20 30 40 50 60 pF1KB6 MASGCKIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 MASGCKIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LGQDPFFDMHMMVSKPEQWVKPMAVAGANQYTFHLEATENPGALIKDIRENGMKVGLAIK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 LGQDPFFDMHMMVSKPEQWVKPMAVAGANQYTFHLEATENPGALIKDIRENGMKVGLAIK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 PGTSVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKVHWLRTQFPSLDIEVDGGVGP ::::::::::::::::::::::::::::::::::::::: CCDS63 PGTSVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPK--------------------- 130 140 150 190 200 210 220 pF1KB6 DTVHKCAEAGANMIVSGSAIMRSEDPRSVINLLRNVCSEAAQKRSLDR :::::::::::::::::::::::::::::::::::::::: CCDS63 --------AGANMIVSGSAIMRSEDPRSVINLLRNVCSEAAQKRSLDR 160 170 180 190 >>CCDS63108.1 RPE gene_id:6120|Hs108|chr2 (160 aa) initn: 1081 init1: 1081 opt: 1081 Z-score: 1399.4 bits: 265.7 E(32554): 1.3e-71 Smith-Waterman score: 1081; 100.0% identity (100.0% similar) in 160 aa overlap (69-228:1-160) 40 50 60 70 80 90 pF1KB6 MDGHFVPNITFGHPVVESLRKQLGQDPFFDMHMMVSKPEQWVKPMAVAGANQYTFHLEAT :::::::::::::::::::::::::::::: CCDS63 MHMMVSKPEQWVKPMAVAGANQYTFHLEAT 10 20 30 100 110 120 130 140 150 pF1KB6 ENPGALIKDIRENGMKVGLAIKPGTSVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 ENPGALIKDIRENGMKVGLAIKPGTSVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMP 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB6 KVHWLRTQFPSLDIEVDGGVGPDTVHKCAEAGANMIVSGSAIMRSEDPRSVINLLRNVCS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 KVHWLRTQFPSLDIEVDGGVGPDTVHKCAEAGANMIVSGSAIMRSEDPRSVINLLRNVCS 100 110 120 130 140 150 220 pF1KB6 EAAQKRSLDR :::::::::: CCDS63 EAAQKRSLDR 160 >>CCDS42810.1 RPE gene_id:6120|Hs108|chr2 (178 aa) initn: 773 init1: 773 opt: 773 Z-score: 1002.3 bits: 192.3 E(32554): 1.7e-49 Smith-Waterman score: 1035; 89.9% identity (89.9% similar) in 178 aa overlap (69-228:1-178) 40 50 60 70 80 90 pF1KB6 MDGHFVPNITFGHPVVESLRKQLGQDPFFDMHMMVSKPEQWVKPMAVAGANQYTFHLEAT :::::::::::::::::::::::::::::: CCDS42 MHMMVSKPEQWVKPMAVAGANQYTFHLEAT 10 20 30 100 110 120 130 140 pF1KB6 ENPGALIKDIRENGMK------------------VGLAIKPGTSVEYLAPWANQIDMALV :::::::::::::::: :::::::::::::::::::::::::: CCDS42 ENPGALIKDIRENGMKSCSVTQAEVQWHSQGPLQVGLAIKPGTSVEYLAPWANQIDMALV 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB6 MTVEPGFGGQKFMEDMMPKVHWLRTQFPSLDIEVDGGVGPDTVHKCAEAGANMIVSGSAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS42 MTVEPGFGGQKFMEDMMPKVHWLRTQFPSLDIEVDGGVGPDTVHKCAEAGANMIVSGSAI 100 110 120 130 140 150 210 220 pF1KB6 MRSEDPRSVINLLRNVCSEAAQKRSLDR :::::::::::::::::::::::::::: CCDS42 MRSEDPRSVINLLRNVCSEAAQKRSLDR 160 170 228 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 12:02:02 2016 done: Fri Nov 4 12:02:03 2016 Total Scan time: 1.410 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]