FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6934, 219 aa 1>>>pF1KB6934 219 - 219 aa - 219 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.6235+/-0.00028; mu= 8.3273+/- 0.018 mean_var=101.4736+/-20.221, 0's: 0 Z-trim(122.3): 4 B-trim: 1416 in 1/52 Lambda= 0.127320 statistics sampled from 40190 (40194) to 40190 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.808), E-opt: 0.2 (0.471), width: 16 Scan time: 7.050 The best scores are: opt bits E(85289) NP_004322 (OMIM: 605368) BCL2/adenovirus E1B 19 kD ( 219) 1488 282.7 3.2e-76 NP_001317420 (OMIM: 605368) BCL2/adenovirus E1B 19 ( 179) 1194 228.7 4.9e-60 NP_004043 (OMIM: 603293) BCL2/adenovirus E1B 19 kD ( 259) 723 142.2 7.4e-34 >>NP_004322 (OMIM: 605368) BCL2/adenovirus E1B 19 kDa pr (219 aa) initn: 1488 init1: 1488 opt: 1488 Z-score: 1489.3 bits: 282.7 E(85289): 3.2e-76 Smith-Waterman score: 1488; 100.0% identity (100.0% similar) in 219 aa overlap (1-219:1-219) 10 20 30 40 50 60 pF1KB6 MSSHLVEPPPPLHNNNNNCEENEQSLPPPAGLNSSWVELPMNSSNGNDNGNGKNGGLEHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MSSHLVEPPPPLHNNNNNCEENEQSLPPPAGLNSSWVELPMNSSNGNDNGNGKNGGLEHV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 PSSSSIHNGDMEKILLDAQHESGQSSSRGSSHCDSPSPQEDGQIMFDVEMHTSRDHSSQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 PSSSSIHNGDMEKILLDAQHESGQSSSRGSSHCDSPSPQEDGQIMFDVEMHTSRDHSSQS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 EEEVVEGEKEVEALKKSADWVSDWSSRPENIPPKEFHFRHPKRSVSLSMRKSGAMKKGGI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EEEVVEGEKEVEALKKSADWVSDWSSRPENIPPKEFHFRHPKRSVSLSMRKSGAMKKGGI 130 140 150 160 170 180 190 200 210 pF1KB6 FSAEFLKVFIPSLFLSHVLALGLGIYIGKRLSTPSASTY ::::::::::::::::::::::::::::::::::::::: NP_004 FSAEFLKVFIPSLFLSHVLALGLGIYIGKRLSTPSASTY 190 200 210 >>NP_001317420 (OMIM: 605368) BCL2/adenovirus E1B 19 kDa (179 aa) initn: 1194 init1: 1194 opt: 1194 Z-score: 1198.8 bits: 228.7 E(85289): 4.9e-60 Smith-Waterman score: 1194; 100.0% identity (100.0% similar) in 179 aa overlap (41-219:1-179) 20 30 40 50 60 70 pF1KB6 PLHNNNNNCEENEQSLPPPAGLNSSWVELPMNSSNGNDNGNGKNGGLEHVPSSSSIHNGD :::::::::::::::::::::::::::::: NP_001 MNSSNGNDNGNGKNGGLEHVPSSSSIHNGD 10 20 30 80 90 100 110 120 130 pF1KB6 MEKILLDAQHESGQSSSRGSSHCDSPSPQEDGQIMFDVEMHTSRDHSSQSEEEVVEGEKE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEKILLDAQHESGQSSSRGSSHCDSPSPQEDGQIMFDVEMHTSRDHSSQSEEEVVEGEKE 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB6 VEALKKSADWVSDWSSRPENIPPKEFHFRHPKRSVSLSMRKSGAMKKGGIFSAEFLKVFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VEALKKSADWVSDWSSRPENIPPKEFHFRHPKRSVSLSMRKSGAMKKGGIFSAEFLKVFI 100 110 120 130 140 150 200 210 pF1KB6 PSLFLSHVLALGLGIYIGKRLSTPSASTY ::::::::::::::::::::::::::::: NP_001 PSLFLSHVLALGLGIYIGKRLSTPSASTY 160 170 >>NP_004043 (OMIM: 603293) BCL2/adenovirus E1B 19 kDa pr (259 aa) initn: 606 init1: 446 opt: 723 Z-score: 728.8 bits: 142.2 E(85289): 7.4e-34 Smith-Waterman score: 723; 62.4% identity (84.0% similar) in 194 aa overlap (32-219:79-259) 10 20 30 40 50 60 pF1KB6 SSHLVEPPPPLHNNNNNCEENEQSLPPPAGLNSSWVELPMNSSNGNDNGNGKNGGLEHVP :..::::: . :.::: :: :: NP_004 HPAARRGLRSPQLPSGAMSQNGAPGMQEESLQGSWVELHF-SNNGN-------GG--SVP 50 60 70 80 90 70 80 90 100 110 pF1KB6 SSSSIHNGDMEKILLDAQHESGQSSSRGSSHCDSP----SPQEDGQIMFDVEMHT-SRDH .: ::.::::::::::::::::.:::. ::::::: .::. .. ... :. .. . NP_004 ASVSIYNGDMEKILLDAQHESGRSSSK-SSHCDSPPRSQTPQDTNRAS-ETDTHSIGEKN 100 110 120 130 140 150 120 130 140 150 160 170 pF1KB6 SSQSEEEVVEGEKEVEA-LKKSADWVSDWSSRPENIPPKEFHFRHPKRSVSLSMRKSGAM ::::::. .: .::::. :::..::. :::::::::::::: :.::::...::::....: NP_004 SSQSEEDDIERRKEVESILKKNSDWIWDWSSRPENIPPKEFLFKHPKRTATLSMRNTSVM 160 170 180 190 200 210 180 190 200 210 pF1KB6 KKGGIFSAEFLKVFIPSLFLSHVLALGLGIYIGKRLSTPSASTY ::::::::::::::.:::.:::.::.:::::::.::.: :.::. NP_004 KKGGIFSAEFLKVFLPSLLLSHLLAIGLGIYIGRRLTT-STSTF 220 230 240 250 219 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 11:57:10 2016 done: Sat Nov 5 11:57:11 2016 Total Scan time: 7.050 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]