FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6938, 229 aa 1>>>pF1KB6938 229 - 229 aa - 229 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1896+/-0.000899; mu= 15.1880+/- 0.054 mean_var=74.0425+/-14.632, 0's: 0 Z-trim(106.4): 94 B-trim: 0 in 0/50 Lambda= 0.149051 statistics sampled from 8893 (8990) to 8893 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.651), E-opt: 0.2 (0.276), width: 16 Scan time: 1.490 The best scores are: opt bits E(32554) CCDS41752.1 CLEC1B gene_id:51266|Hs108|chr12 ( 229) 1588 350.5 5.2e-97 CCDS41751.1 CLEC1B gene_id:51266|Hs108|chr12 ( 196) 1238 275.2 2.1e-74 CCDS73443.1 CLEC1A gene_id:51267|Hs108|chr12 ( 247) 387 92.3 3.1e-19 CCDS8612.1 CLEC1A gene_id:51267|Hs108|chr12 ( 280) 387 92.3 3.4e-19 CCDS44830.1 CLEC12B gene_id:387837|Hs108|chr12 ( 276) 369 88.4 4.9e-18 CCDS41753.1 CLEC7A gene_id:64581|Hs108|chr12 ( 247) 364 87.3 9.4e-18 CCDS76528.1 CLEC1A gene_id:51267|Hs108|chr12 ( 188) 348 83.8 8.3e-17 CCDS8613.1 CLEC7A gene_id:64581|Hs108|chr12 ( 201) 302 73.9 8.3e-14 CCDS8614.1 CLEC7A gene_id:64581|Hs108|chr12 ( 168) 301 73.7 8.4e-14 CCDS8609.1 CLEC12A gene_id:160364|Hs108|chr12 ( 232) 301 73.8 1.1e-13 CCDS8608.1 CLEC12A gene_id:160364|Hs108|chr12 ( 265) 301 73.8 1.2e-13 CCDS55803.1 CLEC12A gene_id:160364|Hs108|chr12 ( 275) 301 73.8 1.2e-13 CCDS8623.1 KLRK1 gene_id:22914|Hs108|chr12 ( 216) 285 70.3 1.1e-12 CCDS8618.1 OLR1 gene_id:4973|Hs108|chr12 ( 273) 283 70.0 1.8e-12 CCDS8610.1 CLEC12B gene_id:387837|Hs108|chr12 ( 232) 280 69.3 2.5e-12 CCDS8622.1 KLRD1 gene_id:3824|Hs108|chr12 ( 148) 265 65.9 1.6e-11 CCDS8621.1 KLRD1 gene_id:3824|Hs108|chr12 ( 179) 265 65.9 1.9e-11 CCDS8611.1 CLEC9A gene_id:283420|Hs108|chr12 ( 241) 265 66.0 2.4e-11 CCDS73442.1 CLEC12A gene_id:160364|Hs108|chr12 ( 213) 258 64.5 6.1e-11 >>CCDS41752.1 CLEC1B gene_id:51266|Hs108|chr12 (229 aa) initn: 1588 init1: 1588 opt: 1588 Z-score: 1855.1 bits: 350.5 E(32554): 5.2e-97 Smith-Waterman score: 1588; 98.7% identity (99.1% similar) in 229 aa overlap (1-229:1-229) 10 20 30 40 50 60 pF1KB6 MQDEDGYITLNIKTRKPALVSVGPASSSWWRVMALILLILCVGMVVGLVALGIWSVMQRN :::::::::::::::::::.::: :::::::::::::::::::::::::::::::::::: CCDS41 MQDEDGYITLNIKTRKPALISVGSASSSWWRVMALILLILCVGMVVGLVALGIWSVMQRN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 YLQDENENRTGTLQQLAKRFCQYVVKQSELKGTFKGHKCSPCDTNWRYYGDSCYGFFRHN ::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 YLQGENENRTGTLQQLAKRFCQYVVKQSELKGTFKGHKCSPCDTNWRYYGDSCYGFFRHN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LTWEESKQYCTDMNATLLKIDNRNIVEYIKARTHLIRWVGLSRQKSNEVWKWEDGSVISE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 LTWEESKQYCTDMNATLLKIDNRNIVEYIKARTHLIRWVGLSRQKSNEVWKWEDGSVISE 130 140 150 160 170 180 190 200 210 220 pF1KB6 NMFEFLEDGKGNMNCAYFHNGKMHPTFCENKHYLMCERKAGMTKVDQLP ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 NMFEFLEDGKGNMNCAYFHNGKMHPTFCENKHYLMCERKAGMTKVDQLP 190 200 210 220 >>CCDS41751.1 CLEC1B gene_id:51266|Hs108|chr12 (196 aa) initn: 1238 init1: 1238 opt: 1238 Z-score: 1449.3 bits: 275.2 E(32554): 2.1e-74 Smith-Waterman score: 1293; 84.3% identity (85.2% similar) in 229 aa overlap (1-229:1-196) 10 20 30 40 50 60 pF1KB6 MQDEDGYITLNIKTRKPALVSVGPASSSWWRVMALILLILCVGMVVGLVALGIWSVMQRN :::::::::::::::::::.: .::::: CCDS41 MQDEDGYITLNIKTRKPALIS---------------------------------AVMQRN 10 20 70 80 90 100 110 120 pF1KB6 YLQDENENRTGTLQQLAKRFCQYVVKQSELKGTFKGHKCSPCDTNWRYYGDSCYGFFRHN ::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 YLQGENENRTGTLQQLAKRFCQYVVKQSELKGTFKGHKCSPCDTNWRYYGDSCYGFFRHN 30 40 50 60 70 80 130 140 150 160 170 180 pF1KB6 LTWEESKQYCTDMNATLLKIDNRNIVEYIKARTHLIRWVGLSRQKSNEVWKWEDGSVISE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 LTWEESKQYCTDMNATLLKIDNRNIVEYIKARTHLIRWVGLSRQKSNEVWKWEDGSVISE 90 100 110 120 130 140 190 200 210 220 pF1KB6 NMFEFLEDGKGNMNCAYFHNGKMHPTFCENKHYLMCERKAGMTKVDQLP ::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 NMFEFLEDGKGNMNCAYFHNGKMHPTFCENKHYLMCERKAGMTKVDQLP 150 160 170 180 190 >>CCDS73443.1 CLEC1A gene_id:51267|Hs108|chr12 (247 aa) initn: 340 init1: 214 opt: 387 Z-score: 458.9 bits: 92.3 E(32554): 3.1e-19 Smith-Waterman score: 387; 31.2% identity (67.6% similar) in 173 aa overlap (62-228:70-236) 40 50 60 70 80 90 pF1KB6 VMALILLILCVGMVVGLVALGIWSVMQRNYLQDENENRTGTLQQLAKRFCQYVVKQSELK :: .: . .:.::..:...:. :: CCDS73 FQYYQLSNTGQDTISQMEERLGNTSQELQSLQVQNIKLAGSLQHVAEKLCR------ELY 40 50 60 70 80 90 100 110 120 130 140 150 pF1KB6 GTFKGHKCSPCDTNWRYYGDSCYGFFRHNLTWEESKQYCTDMNATLLKIDNRNIVEYIKA . .:.:::: .:...::.:: :.. . .::. : .: . :.:.:::.... .:. . CCDS73 NKAGAHRCSPCTEQWKWHGDNCYQFYKDSKSWEDCKYFCLSENSTMLKINKQEDLEFAAS 100 110 120 130 140 150 160 170 180 190 200 pF1KB6 RTH----LIRWVGLSRQKSNEVWKWEDGSVISENMFEFLED--GKGNMNCAYFHNGKMHP ... :.:: : :...: : ::. .. ..:... : . . .:. . :: . CCDS73 QSYSEFFYSYWTGLLRPDSGKAWLWMDGTPFTSELFHIIIDVTSPRSRDCVAILNGMIFS 160 170 180 190 200 210 210 220 pF1KB6 TFCENKHYLMCERKAGMTKVDQLP :.. . .:::.:::.: ..: CCDS73 KDCKELKRCVCERRAGMVKPESLHVPPETLGEGD 220 230 240 >>CCDS8612.1 CLEC1A gene_id:51267|Hs108|chr12 (280 aa) initn: 431 init1: 214 opt: 387 Z-score: 458.1 bits: 92.3 E(32554): 3.4e-19 Smith-Waterman score: 444; 30.2% identity (60.0% similar) in 265 aa overlap (1-228:11-269) 10 20 30 40 pF1KB6 MQDEDGYITLNIK------TRKPA-LVSVGPASSSWWRVMALILLILCVG : :.:: :.... ::.: . : :: :: .:: :: ::. CCDS86 MQAKYSSTRDMLDDDGDTTMSLHSQGSATTRHPEPRRTEHRAPSSTWRPVALTLLTLCLV 10 20 30 40 50 60 50 60 70 pF1KB6 MVVGLVALGIW---------------SVMQRNY---------LQDENENRTGTLQQLAKR ...::.:::. : :.. :: .: . .:.::..:.. CCDS86 LLIGLAALGLLFFQYYQLSNTGQDTISQMEERLGNTSQELQSLQVQNIKLAGSLQHVAEK 70 80 90 100 110 120 80 90 100 110 120 130 pF1KB6 FCQYVVKQSELKGTFKGHKCSPCDTNWRYYGDSCYGFFRHNLTWEESKQYCTDMNATLLK .:. :: . .:.:::: .:...::.:: :.. . .::. : .: . :.:.:: CCDS86 LCR------ELYNKAGAHRCSPCTEQWKWHGDNCYQFYKDSKSWEDCKYFCLSENSTMLK 130 140 150 160 170 140 150 160 170 180 190 pF1KB6 IDNRNIVEYIKARTH----LIRWVGLSRQKSNEVWKWEDGSVISENMFEFLED--GKGNM :.... .:. .... :.:: : :...: : ::. .. ..:... : . . CCDS86 INKQEDLEFAASQSYSEFFYSYWTGLLRPDSGKAWLWMDGTPFTSELFHIIIDVTSPRSR 180 190 200 210 220 230 200 210 220 pF1KB6 NCAYFHNGKMHPTFCENKHYLMCERKAGMTKVDQLP .:. . :: . :.. . .:::.:::.: ..: CCDS86 DCVAILNGMIFSKDCKELKRCVCERRAGMVKPESLHVPPETLGEGD 240 250 260 270 280 >>CCDS44830.1 CLEC12B gene_id:387837|Hs108|chr12 (276 aa) initn: 437 init1: 103 opt: 369 Z-score: 437.3 bits: 88.4 E(32554): 4.9e-18 Smith-Waterman score: 392; 30.9% identity (60.1% similar) in 243 aa overlap (24-228:33-275) 10 20 30 40 50 pF1KB6 MQDEDGYITLNIKTRKPALVSVGPASSSWWRVMALILLILCVGMVVGLVALGI :: : :: :: :. ::. ...:::.::. CCDS44 EEVTYATLTFQDSAGARNNRDGNNLRKRGHPAPSPIWRHAALGLVTLCLMLLIGLVTLGM 10 20 30 40 50 60 60 70 80 pF1KB6 WSVMQRNYLQDENENRTG---TLQQ----------------------------LAKRFCQ .. : .....:. . :.:: . :: : CCDS44 MFLQISNDINSDSEKLSQLQKTIQQQQDNLSQQLGNSNNLSMEEEFLKSQISSVLKRQEQ 70 80 90 100 110 120 90 100 110 120 130 140 pF1KB6 YVVKQ-SELKGTFKGHKCSPCDTNWRYYGDSCYGFFRHNL-TWEESKQYCTDMNATLLKI ...: .:: . :.:.:: :..: .::: : .. :: .:.. : : :.::.:: CCDS44 MAIKLCQELIIHTSDHRCNPCPKMWQWYQNSCYYFTTNEEKTWANSRKDCIDKNSTLVKI 130 140 150 160 170 180 150 160 170 180 190 pF1KB6 DNRNIVEYIKARTHLIR---WVGLSRQKSNEVWKWEDGSVISENMF--EFLEDGKGNMNC :. . ... .. :. :.::: ..:.. : :::::: : ..: . :.. .:. .: CCDS44 DSLEEKDFLMSQPLLMFSFFWLGLSWDSSGRSWFWEDGSVPSPSLFSTKELDQINGSKGC 190 200 210 220 230 240 200 210 220 pF1KB6 AYFHNGKMHPTFCENKHYLMCERKAGMTKVDQLP :::..:... . : . . .::. :. .:...: CCDS44 AYFQKGNIYISRCSAEIFWICEKTAAPVKTEDLD 250 260 270 >>CCDS41753.1 CLEC7A gene_id:64581|Hs108|chr12 (247 aa) initn: 416 init1: 140 opt: 364 Z-score: 432.2 bits: 87.3 E(32554): 9.4e-18 Smith-Waterman score: 390; 32.6% identity (59.4% similar) in 239 aa overlap (3-222:11-247) 10 20 30 40 pF1KB6 MQDEDGYITLNIKTRKPALVSV----GP-ASSSWWRVMALILLILCVGMVVG ::::: :.. ... . ..: : :.: ::..:.:: :::. ..: CCDS41 MEYHPDLENLDEDGYTQLHFDSQSNTRIAVVSEKGSCAASPPWRLIAVILGILCLVILVI 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB6 LVALG---IW-SVMQRNYLQDE---NENRTGTLQQLAKRFCQYVVKQSELKGTFKGHKCS :.:: :: : : :.. ..:. . : . . . :. . .: : : : CCDS41 AVVLGTMAIWRSNSGSNTLENGYFLSRNKENHSQPTQSSLEDSVTPTKAVKTT--GVLSS 70 80 90 100 110 110 120 130 140 150 pF1KB6 PCDTNWRYYGDSCYGFFRHNLTWEESKQYCTDMNATLLKIDNRN----IVEYIKARTHLI :: :: : ::: : .:. ::. : .....:::::. : ::. .... CCDS41 PCPPNWIIYEKSCYLFSMSLNSWDGSKRQCWQLGSNLLKIDSSNELGFIVKQVSSQPDNS 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB6 RWVGLSRQKSNEVWKWEDGSVISENMFEFLEDG---KGNMNCAYFHNGKMHPTFCENKHY :.:::: ... : :::::..: :.:.. . . . ::...: . .. .: : CCDS41 FWIGLSRPQTEVPWLWEDGSTFSSNLFQIRTTATQENPSPNCVWIHVSVIYDQLCSVPSY 180 190 200 210 220 230 220 pF1KB6 LMCERKAGMTKVDQLP .::.: .: CCDS41 SICEKKFSM 240 >>CCDS76528.1 CLEC1A gene_id:51267|Hs108|chr12 (188 aa) initn: 324 init1: 198 opt: 348 Z-score: 415.2 bits: 83.8 E(32554): 8.3e-17 Smith-Waterman score: 348; 31.9% identity (68.8% similar) in 138 aa overlap (97-228:40-177) 70 80 90 100 110 120 pF1KB6 ENRTGTLQQLAKRFCQYVVKQSELKGTFKGHKCSPCDTNWRYYGDSCYGFFRHNLTWEES :.:::: .:...::.:: :.. . .::. CCDS76 DMLDDDGDTTMSLHSQGSATTRHPEPRRTAHRCSPCTEQWKWHGDNCYQFYKDSKSWEDC 10 20 30 40 50 60 130 140 150 160 170 180 pF1KB6 KQYCTDMNATLLKIDNRNIVEYIKARTH----LIRWVGLSRQKSNEVWKWEDGSVISENM : .: . :.:.:::.... .:. .... :.:: : :...: : ::. .. .. CCDS76 KYFCLSENSTMLKINKQEDLEFAASQSYSEFFYSYWTGLLRPDSGKAWLWMDGTPFTSEL 70 80 90 100 110 120 190 200 210 220 pF1KB6 FEFLED--GKGNMNCAYFHNGKMHPTFCENKHYLMCERKAGMTKVDQLP :... : . . .:. . :: . :.. . .:::.:::.: ..: CCDS76 FHIIIDVTSPRSRDCVAILNGMIFSKDCKELKRCVCERRAGMVKPESLHVPPETLGEGD 130 140 150 160 170 180 >>CCDS8613.1 CLEC7A gene_id:64581|Hs108|chr12 (201 aa) initn: 409 init1: 140 opt: 302 Z-score: 361.4 bits: 73.9 E(32554): 8.3e-14 Smith-Waterman score: 318; 29.3% identity (53.0% similar) in 232 aa overlap (3-222:11-201) 10 20 30 40 pF1KB6 MQDEDGYITLNIKTRKPALVSV----GP-ASSSWWRVMALILLILCVGMVVG ::::: :.. ... . ..: : :.: ::..:.:: :::. ..: CCDS86 MEYHPDLENLDEDGYTQLHFDSQSNTRIAVVSEKGSCAASPPWRLIAVILGILCLVILVI 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB6 LVALGIWSVMQRNYLQDENENRTGTLQQLAKRFCQYVVKQSELKGTFKGHKCSPCDTNWR :.:: .:.. ::: :: CCDS86 AVVLGTMGVLS-----------------------------------------SPCPPNWI 70 110 120 130 140 150 160 pF1KB6 YYGDSCYGFFRHNLTWEESKQYCTDMNATLLKIDNRN----IVEYIKARTHLIRWVGLSR : ::: : .:. ::. : .....:::::. : ::. .... :.:::: CCDS86 IYEKSCYLFSMSLNSWDGSKRQCWQLGSNLLKIDSSNELGFIVKQVSSQPDNSFWIGLSR 80 90 100 110 120 130 170 180 190 200 210 220 pF1KB6 QKSNEVWKWEDGSVISENMFEFLEDG---KGNMNCAYFHNGKMHPTFCENKHYLMCERKA ... : :::::..: :.:.. . . . ::...: . .. .: : .::.: CCDS86 PQTEVPWLWEDGSTFSSNLFQIRTTATQENPSPNCVWIHVSVIYDQLCSVPSYSICEKKF 140 150 160 170 180 190 pF1KB6 GMTKVDQLP .: CCDS86 SM 200 >>CCDS8614.1 CLEC7A gene_id:64581|Hs108|chr12 (168 aa) initn: 346 init1: 146 opt: 301 Z-score: 361.3 bits: 73.7 E(32554): 8.4e-14 Smith-Waterman score: 301; 34.8% identity (61.5% similar) in 135 aa overlap (95-222:34-168) 70 80 90 100 110 120 pF1KB6 ENENRTGTLQQLAKRFCQYVVKQSELKGTFKGHKCSPCDTNWRYYGDSCYGFFRHNLTWE :: ::: :: : ::: : .:. CCDS86 HPDLENLDEDGYTQLHFDSQSNTRIAVVSEKGVLSSPCPPNWIIYEKSCYLFSMSLNSWD 10 20 30 40 50 60 130 140 150 160 170 180 pF1KB6 ESKQYCTDMNATLLKIDNRN----IVEYIKARTHLIRWVGLSRQKSNEVWKWEDGSVISE ::. : .....:::::. : ::. .... :.:::: ... : :::::..: CCDS86 GSKRQCWQLGSNLLKIDSSNELGFIVKQVSSQPDNSFWIGLSRPQTEVPWLWEDGSTFSS 70 80 90 100 110 120 190 200 210 220 pF1KB6 NMFEFLEDG---KGNMNCAYFHNGKMHPTFCENKHYLMCERKAGMTKVDQLP :.:.. . . . ::...: . .. .: : .::.: .: CCDS86 NLFQIRTTATQENPSPNCVWIHVSVIYDQLCSVPSYSICEKKFSM 130 140 150 160 >>CCDS8609.1 CLEC12A gene_id:160364|Hs108|chr12 (232 aa) initn: 267 init1: 213 opt: 301 Z-score: 359.3 bits: 73.8 E(32554): 1.1e-13 Smith-Waterman score: 301; 31.1% identity (61.1% similar) in 167 aa overlap (56-220:60-219) 30 40 50 60 70 80 pF1KB6 SSSWWRVMALILLILCVGMVVGLVALGIWSVMQRNYLQDENENRTGTLQQLAKRFCQYVV .:. .... .: . ::: .: ..:. CCDS86 KVHVTLKIEMKKMNKLQNISEELQRNISLQLMSNMNISNKIRNLSTTLQTIATKLCR--- 30 40 50 60 70 80 90 100 110 120 130 140 pF1KB6 KQSELKGTFKGHKCSPCDTNWRYYGDSCYGFFRHNL-TWEESKQYCTDMNATLLKIDNRN :: . . :::.:: : .. :::: :. .. ::.:::. :. .::.::::.:.: CCDS86 ---ELYSKEQEHKCKPCPRRWIWHKDSCY-FLSDDVQTWQESKMACAAQNASLLKINNKN 90 100 110 120 130 140 150 160 170 180 190 200 pF1KB6 IVEYIKARTHLI-RWVGLSRQKSNEVWKWEDGSVISENMFEFLEDGKGNMNCAYFHNGKM .:.::.... :.::: .... :. . : .:: :.:.. . CCDS86 ALEFIKSQSRSYDYWLGLSPEEDSTRGMRVDNIINSSAWVIRNAPDLNNMYCGYINRLYV 150 160 170 180 190 200 210 220 pF1KB6 HPTFCENKHYLMCERKAGMTKVDQLP . : :. ..::. : CCDS86 QYYHCTYKKRMICEKMANPVQLGSTYFREA 210 220 230 229 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 11:47:31 2016 done: Fri Nov 4 11:47:31 2016 Total Scan time: 1.490 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]