FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6939, 208 aa 1>>>pF1KB6939 208 - 208 aa - 208 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.4243+/-0.000301; mu= 11.1567+/- 0.019 mean_var=159.1408+/-33.306, 0's: 0 Z-trim(121.7): 235 B-trim: 0 in 0/58 Lambda= 0.101668 statistics sampled from 38295 (38580) to 38295 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.78), E-opt: 0.2 (0.452), width: 16 Scan time: 6.490 The best scores are: opt bits E(85289) NP_001303 (OMIM: 601183) cysteine-rich protein 2 i ( 208) 1528 234.8 7.5e-62 NP_001257766 (OMIM: 601183) cysteine-rich protein ( 282) 1423 219.6 4e-57 NP_001257770 (OMIM: 601183) cysteine-rich protein ( 87) 619 101.1 5.8e-22 NP_001302 (OMIM: 123875) cysteine-rich protein 1 [ ( 77) 427 72.8 1.6e-13 NP_004069 (OMIM: 123876) cysteine and glycine-rich ( 193) 293 53.7 2.4e-07 NP_001180501 (OMIM: 123876) cysteine and glycine-r ( 193) 293 53.7 2.4e-07 NP_001180500 (OMIM: 123876) cysteine and glycine-r ( 193) 293 53.7 2.4e-07 NP_003467 (OMIM: 600824,607482,612124) cysteine an ( 194) 282 52.0 7.4e-07 NP_001180499 (OMIM: 123876) cysteine and glycine-r ( 187) 268 50.0 3e-06 NP_001312 (OMIM: 601871) cysteine and glycine-rich ( 193) 262 49.1 5.7e-06 NP_001287894 (OMIM: 601871) cysteine and glycine-r ( 193) 262 49.1 5.7e-06 NP_004459 (OMIM: 602790) four and a half LIM domai ( 280) 230 44.6 0.00019 XP_016859581 (OMIM: 602567) PREDICTED: LIM and sen ( 317) 216 42.6 0.00084 XP_016859582 (OMIM: 602567) PREDICTED: LIM and sen ( 317) 216 42.6 0.00084 XP_016859583 (OMIM: 602567) PREDICTED: LIM and sen ( 317) 216 42.6 0.00084 XP_016859580 (OMIM: 602567) PREDICTED: LIM and sen ( 317) 216 42.6 0.00084 NP_001180417 (OMIM: 602567) LIM and senescent cell ( 325) 216 42.6 0.00085 NP_004978 (OMIM: 602567) LIM and senescent cell an ( 325) 216 42.6 0.00085 NP_001180411 (OMIM: 602567) LIM and senescent cell ( 329) 216 42.6 0.00086 XP_005264008 (OMIM: 602567) PREDICTED: LIM and sen ( 336) 216 42.6 0.00087 XP_005264007 (OMIM: 602567) PREDICTED: LIM and sen ( 336) 216 42.6 0.00087 NP_001180412 (OMIM: 602567) LIM and senescent cell ( 337) 216 42.6 0.00087 XP_005264006 (OMIM: 602567) PREDICTED: LIM and sen ( 348) 216 42.7 0.00089 NP_001180413 (OMIM: 602567) LIM and senescent cell ( 362) 216 42.7 0.00092 XP_005264005 (OMIM: 602567) PREDICTED: LIM and sen ( 373) 216 42.7 0.00093 NP_001180414 (OMIM: 602567) LIM and senescent cell ( 387) 216 42.7 0.00096 XP_005264003 (OMIM: 602567) PREDICTED: LIM and sen ( 398) 216 42.7 0.00098 XP_005263767 (OMIM: 607908,616827) PREDICTED: LIM ( 272) 212 41.9 0.0011 NP_001154876 (OMIM: 607908,616827) LIM and senesce ( 336) 212 42.0 0.0013 NP_001154875 (OMIM: 607908,616827) LIM and senesce ( 341) 212 42.1 0.0013 NP_001129509 (OMIM: 607908,616827) LIM and senesce ( 363) 212 42.1 0.0014 NP_060450 (OMIM: 607908,616827) LIM and senescent ( 365) 212 42.1 0.0014 NP_963849 (OMIM: 602633) four and a half LIM domai ( 279) 194 39.3 0.0072 NP_001305823 (OMIM: 602633) four and a half LIM do ( 279) 194 39.3 0.0072 NP_963851 (OMIM: 602633) four and a half LIM domai ( 279) 194 39.3 0.0072 NP_001034581 (OMIM: 602633) four and a half LIM do ( 279) 194 39.3 0.0072 NP_001441 (OMIM: 602633) four and a half LIM domai ( 279) 194 39.3 0.0072 XP_011509100 (OMIM: 602633) PREDICTED: four and a ( 279) 194 39.3 0.0072 NP_001305824 (OMIM: 602633) four and a half LIM do ( 279) 194 39.3 0.0072 NP_001305825 (OMIM: 602633) four and a half LIM do ( 279) 194 39.3 0.0072 >>NP_001303 (OMIM: 601183) cysteine-rich protein 2 isofo (208 aa) initn: 1528 init1: 1528 opt: 1528 Z-score: 1231.4 bits: 234.8 E(85289): 7.5e-62 Smith-Waterman score: 1528; 100.0% identity (100.0% similar) in 208 aa overlap (1-208:1-208) 10 20 30 40 50 60 pF1KB6 MASKCPKCDKTVYFAEKVSSLGKDWHKFCLKCERCSKTLTPGGHAEHDGKPFCHKPCYAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MASKCPKCDKTVYFAEKVSSLGKDWHKFCLKCERCSKTLTPGGHAEHDGKPFCHKPCYAT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LFGPKGVNIGGAGSYIYEKPLAEGPQVTGPIEVPAARAEERKASGPPKGPSRASSVTTFT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFGPKGVNIGGAGSYIYEKPLAEGPQVTGPIEVPAARAEERKASGPPKGPSRASSVTTFT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 GEPNTCPRCSKKVYFAEKVTSLGKDWHRPCLRCERCGKTLTPGGHAEHDGQPYCHKPCYG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GEPNTCPRCSKKVYFAEKVTSLGKDWHRPCLRCERCGKTLTPGGHAEHDGQPYCHKPCYG 130 140 150 160 170 180 190 200 pF1KB6 ILFGPKGVNTGAVGSYIYDRDPEGKVQP :::::::::::::::::::::::::::: NP_001 ILFGPKGVNTGAVGSYIYDRDPEGKVQP 190 200 >>NP_001257766 (OMIM: 601183) cysteine-rich protein 2 is (282 aa) initn: 1423 init1: 1423 opt: 1423 Z-score: 1146.6 bits: 219.6 E(85289): 4e-57 Smith-Waterman score: 1423; 100.0% identity (100.0% similar) in 194 aa overlap (15-208:89-282) 10 20 30 40 pF1KB6 MASKCPKCDKTVYFAEKVSSLGKDWHKFCLKCERCSKTLTPGGH :::::::::::::::::::::::::::::: NP_001 EPSQDHHESQEHRGPLVGSQTCLVHQAEGTAEKVSSLGKDWHKFCLKCERCSKTLTPGGH 60 70 80 90 100 110 50 60 70 80 90 100 pF1KB6 AEHDGKPFCHKPCYATLFGPKGVNIGGAGSYIYEKPLAEGPQVTGPIEVPAARAEERKAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AEHDGKPFCHKPCYATLFGPKGVNIGGAGSYIYEKPLAEGPQVTGPIEVPAARAEERKAS 120 130 140 150 160 170 110 120 130 140 150 160 pF1KB6 GPPKGPSRASSVTTFTGEPNTCPRCSKKVYFAEKVTSLGKDWHRPCLRCERCGKTLTPGG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GPPKGPSRASSVTTFTGEPNTCPRCSKKVYFAEKVTSLGKDWHRPCLRCERCGKTLTPGG 180 190 200 210 220 230 170 180 190 200 pF1KB6 HAEHDGQPYCHKPCYGILFGPKGVNTGAVGSYIYDRDPEGKVQP :::::::::::::::::::::::::::::::::::::::::::: NP_001 HAEHDGQPYCHKPCYGILFGPKGVNTGAVGSYIYDRDPEGKVQP 240 250 260 270 280 >>NP_001257770 (OMIM: 601183) cysteine-rich protein 2 is (87 aa) initn: 619 init1: 619 opt: 619 Z-score: 515.3 bits: 101.1 E(85289): 5.8e-22 Smith-Waterman score: 619; 96.4% identity (98.8% similar) in 83 aa overlap (126-208:5-87) 100 110 120 130 140 150 pF1KB6 ARAEERKASGPPKGPSRASSVTTFTGEPNTCPRCSKKVYFAEKVTSLGKDWHRPCLRCER ::.:.: ::::::::::::::::::::::: NP_001 MASKCPKCDKTVYFAEKVTSLGKDWHRPCLRCER 10 20 30 160 170 180 190 200 pF1KB6 CGKTLTPGGHAEHDGQPYCHKPCYGILFGPKGVNTGAVGSYIYDRDPEGKVQP ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CGKTLTPGGHAEHDGQPYCHKPCYGILFGPKGVNTGAVGSYIYDRDPEGKVQP 40 50 60 70 80 >>NP_001302 (OMIM: 123875) cysteine-rich protein 1 [Homo (77 aa) initn: 489 init1: 427 opt: 427 Z-score: 363.7 bits: 72.8 E(85289): 1.6e-13 Smith-Waterman score: 427; 68.5% identity (91.8% similar) in 73 aa overlap (126-198:4-76) 100 110 120 130 140 150 pF1KB6 ARAEERKASGPPKGPSRASSVTTFTGEPNTCPRCSKKVYFAEKVTSLGKDWHRPCLRCER ::.:.:.:::::.:::::::::::::.::. NP_001 MPKCPKCNKEVYFAERVTSLGKDWHRPCLKCEK 10 20 30 160 170 180 190 200 pF1KB6 CGKTLTPGGHAEHDGQPYCHKPCYGILFGPKGVNTGAVGSYIYDRDPEGKVQP :::::: ::::::.:.:::..:::. .::::: . :.. :. . NP_001 CGKTLTSGGHAEHEGKPYCNHPCYAAMFGPKGFGRGGAESHTFK 40 50 60 70 >>NP_004069 (OMIM: 123876) cysteine and glycine-rich pro (193 aa) initn: 451 init1: 225 opt: 293 Z-score: 252.8 bits: 53.7 E(85289): 2.4e-07 Smith-Waterman score: 474; 40.1% identity (60.4% similar) in 197 aa overlap (4-198:9-191) 10 20 30 40 50 pF1KB6 MASKCPKCDKTVYFAEKVSSLGKDWHKFCLKCERCSKTLTPGGHAEHDGKPFCHK :: :.:::::::.:. :...:: :. : :.:.: : : . .: : NP_004 MPNWGGGKKCGVCQKTVYFAEEVQCEGNSFHKSCFLCMVCKKNLDSTTVAVHGEEIYC-K 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 PCYATLFGPKGVNIG-GAGSYIYEKPLAEGPQVTGPIEVPAARAEERKASGPPKGPSRAS ::. .:::: . : :::. .: . : . :: . : .:. :: NP_004 SCYGKKYGPKGYGYGQGAGTLSTDKGESLG-----------IKHEEAPGHRPTTNPN-AS 60 70 80 90 100 120 130 140 150 160 170 pF1KB6 SVTTFTGEPNTCPRCSKKVYFAEKVTSLGKDWHRPCLRCERCGKTLTPGGHAEHDGQPYC . . : . :::::. :: :::: . ::.::. :.:: .::: : :..::. :: NP_004 KFAQKIGGSERCPRCSQAVYAAEKVIGAGKSWHKACFRCAKCGKGLESTTLADKDGEIYC 110 120 130 140 150 160 180 190 200 pF1KB6 HKPCYGILFGPKGVNTG-AVGSYIYDRDPEGKVQP : ::. ::::: . : ..:. .. NP_004 -KGCYAKNFGPKGFGFGQGAGALVHSE 170 180 190 >>NP_001180501 (OMIM: 123876) cysteine and glycine-rich (193 aa) initn: 451 init1: 225 opt: 293 Z-score: 252.8 bits: 53.7 E(85289): 2.4e-07 Smith-Waterman score: 474; 40.1% identity (60.4% similar) in 197 aa overlap (4-198:9-191) 10 20 30 40 50 pF1KB6 MASKCPKCDKTVYFAEKVSSLGKDWHKFCLKCERCSKTLTPGGHAEHDGKPFCHK :: :.:::::::.:. :...:: :. : :.:.: : : . .: : NP_001 MPNWGGGKKCGVCQKTVYFAEEVQCEGNSFHKSCFLCMVCKKNLDSTTVAVHGEEIYC-K 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 PCYATLFGPKGVNIG-GAGSYIYEKPLAEGPQVTGPIEVPAARAEERKASGPPKGPSRAS ::. .:::: . : :::. .: . : . :: . : .:. :: NP_001 SCYGKKYGPKGYGYGQGAGTLSTDKGESLG-----------IKHEEAPGHRPTTNPN-AS 60 70 80 90 100 120 130 140 150 160 170 pF1KB6 SVTTFTGEPNTCPRCSKKVYFAEKVTSLGKDWHRPCLRCERCGKTLTPGGHAEHDGQPYC . . : . :::::. :: :::: . ::.::. :.:: .::: : :..::. :: NP_001 KFAQKIGGSERCPRCSQAVYAAEKVIGAGKSWHKACFRCAKCGKGLESTTLADKDGEIYC 110 120 130 140 150 160 180 190 200 pF1KB6 HKPCYGILFGPKGVNTG-AVGSYIYDRDPEGKVQP : ::. ::::: . : ..:. .. NP_001 -KGCYAKNFGPKGFGFGQGAGALVHSE 170 180 190 >>NP_001180500 (OMIM: 123876) cysteine and glycine-rich (193 aa) initn: 451 init1: 225 opt: 293 Z-score: 252.8 bits: 53.7 E(85289): 2.4e-07 Smith-Waterman score: 474; 40.1% identity (60.4% similar) in 197 aa overlap (4-198:9-191) 10 20 30 40 50 pF1KB6 MASKCPKCDKTVYFAEKVSSLGKDWHKFCLKCERCSKTLTPGGHAEHDGKPFCHK :: :.:::::::.:. :...:: :. : :.:.: : : . .: : NP_001 MPNWGGGKKCGVCQKTVYFAEEVQCEGNSFHKSCFLCMVCKKNLDSTTVAVHGEEIYC-K 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 PCYATLFGPKGVNIG-GAGSYIYEKPLAEGPQVTGPIEVPAARAEERKASGPPKGPSRAS ::. .:::: . : :::. .: . : . :: . : .:. :: NP_001 SCYGKKYGPKGYGYGQGAGTLSTDKGESLG-----------IKHEEAPGHRPTTNPN-AS 60 70 80 90 100 120 130 140 150 160 170 pF1KB6 SVTTFTGEPNTCPRCSKKVYFAEKVTSLGKDWHRPCLRCERCGKTLTPGGHAEHDGQPYC . . : . :::::. :: :::: . ::.::. :.:: .::: : :..::. :: NP_001 KFAQKIGGSERCPRCSQAVYAAEKVIGAGKSWHKACFRCAKCGKGLESTTLADKDGEIYC 110 120 130 140 150 160 180 190 200 pF1KB6 HKPCYGILFGPKGVNTG-AVGSYIYDRDPEGKVQP : ::. ::::: . : ..:. .. NP_001 -KGCYAKNFGPKGFGFGQGAGALVHSE 170 180 190 >>NP_003467 (OMIM: 600824,607482,612124) cysteine and gl (194 aa) initn: 465 init1: 220 opt: 282 Z-score: 244.1 bits: 52.0 E(85289): 7.4e-07 Smith-Waterman score: 462; 37.5% identity (61.0% similar) in 200 aa overlap (3-201:8-194) 10 20 30 40 50 pF1KB6 MASKCPKCDKTVYFAEKVSSLGKDWHKFCLKCERCSKTLTPGGHAEHDGKPFCHK .:: :.:::: ::... :...:: :..: : :.: : :... .: : NP_003 MPNWGGGAKCGACEKTVYHAEEIQCNGRSFHKTCFHCMACRKALDSTTVAAHESEIYC-K 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 PCYATLFGPKGVNIG-GAGSYIYEKPLAEGPQVTGPIEVPAARAEERKASGPPKGPSRAS ::. .::::.. : ::: . : : . : :. .:.: : NP_003 VCYGRRYGPKGIGYGQGAGCLSTDTGEHLGLQFQ---QSPKP-ARSVTTSNP-------S 60 70 80 90 100 120 130 140 150 160 170 pF1KB6 SVTTFTGEPNTCPRCSKKVYFAEKVTSLGKDWHRPCLRCERCGKTLTPGGHAEHDGQPYC . :. :: . ::::.:.:: :::: . :: ::. :.:: :::.: . ...::. :: NP_003 KFTAKFGESEKCPRCGKSVYAAEKVMGGGKPWHKTCFRCAICGKSLESTNVTDKDGELYC 110 120 130 140 150 160 180 190 200 pF1KB6 HKPCYGILFGPKGVNTGAVGSYIYDRDPEGKVQP : ::. ::: :.. :.. . . .. NP_003 -KVCYAKNFGPTGIGFGGLTQQVEKKE 170 180 190 >>NP_001180499 (OMIM: 123876) cysteine and glycine-rich (187 aa) initn: 359 init1: 150 opt: 268 Z-score: 233.1 bits: 50.0 E(85289): 3e-06 Smith-Waterman score: 436; 38.6% identity (58.4% similar) in 197 aa overlap (4-198:9-185) 10 20 30 40 50 pF1KB6 MASKCPKCDKTVYFAEKVSSLGKDWHKFCLKCERCSKTLTPGGHAEHDGKPFCHK :: :.:::::::.:. :...:: :. : :.:.: : : . .: : NP_001 MPNWGGGKKCGVCQKTVYFAEEVQCEGNSFHKSCFLCMVCKKNLDSTTVAVHGEEIYC-K 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 PCYATLFGPKGVNIG-GAGSYIYEKPLAEGPQVTGPIEVPAARAEERKASGPPKGPSRAS ::. .:::: . : :::. .: . : . :: . : .:. :: NP_001 SCYGKKYGPKGYGYGQGAGTLSTDKGESLG-----------IKHEEAPGHRPTTNPN-AS 60 70 80 90 100 120 130 140 150 160 170 pF1KB6 SVTTFTGEPNTCPRCSKKVYFAEKVTSLGKDWHRPCLRCERCGKTLTPGGHAEHDGQPYC . . : . :::::. :: ::: .::. :.:: .::: : :..::. :: NP_001 KFAQKIGGSERCPRCSQAVYAAEK------SWHKACFRCAKCGKGLESTTLADKDGEIYC 110 120 130 140 150 160 180 190 200 pF1KB6 HKPCYGILFGPKGVNTG-AVGSYIYDRDPEGKVQP : ::. ::::: . : ..:. .. NP_001 -KGCYAKNFGPKGFGFGQGAGALVHSE 170 180 >>NP_001312 (OMIM: 601871) cysteine and glycine-rich pro (193 aa) initn: 418 init1: 195 opt: 262 Z-score: 228.2 bits: 49.1 E(85289): 5.7e-06 Smith-Waterman score: 437; 35.9% identity (59.1% similar) in 198 aa overlap (3-198:8-191) 10 20 30 40 50 pF1KB6 MASKCPKCDKTVYFAEKVSSLGKDWHKFCLKCERCSKTLTPGGHAEHDGKPFCHK .:: : .::: ::.:. :...:. :. : : :.: : :: . .: : NP_001 MPVWGGGNKCGACGRTVYHAEEVQCDGRSFHRCCFLCMVCRKNLDSTTVAIHDEEIYC-K 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 PCYATLFGPKGVNIG-GAGSYIYEKPLAEGPQVTGPIEVPAARAEERKASGPPKGPSRAS ::. .:::: . : :::. ... : . : : : : .:. .. NP_001 SCYGKKYGPKGYGYGQGAGTLNMDRGERLGIK---PESVQPHR--------PTTNPNTSK 60 70 80 90 100 120 130 140 150 160 170 pF1KB6 SVTTFTGEPNTCPRCSKKVYFAEKVTSLGKDWHRPCLRCERCGKTLTPGGHAEHDGQPYC . . : . : ::. .:: :::. . :: ::. :.:: .:::.: .:..:. :: NP_001 FAQKYGGA-EKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYC 110 120 130 140 150 160 180 190 200 pF1KB6 HKPCYGILFGPKGVNTG-AVGSYIYDRDPEGKVQP : ::. ::::: . : ..:. .. NP_001 -KGCYAKNFGPKGFGYGQGAGALVHAQ 170 180 190 208 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 14:30:14 2016 done: Sat Nov 5 14:30:15 2016 Total Scan time: 6.490 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]