FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6941, 209 aa 1>>>pF1KB6941 209 - 209 aa - 209 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.0378+/-0.000382; mu= 7.6099+/- 0.024 mean_var=158.4794+/-31.600, 0's: 0 Z-trim(118.4): 8 B-trim: 1011 in 1/54 Lambda= 0.101880 statistics sampled from 31312 (31320) to 31312 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.725), E-opt: 0.2 (0.367), width: 16 Scan time: 5.060 The best scores are: opt bits E(85289) NP_056979 (OMIM: 602842,616835) geminin [Homo sapi ( 209) 1328 206.2 3.1e-53 NP_001238918 (OMIM: 602842,616835) geminin [Homo s ( 209) 1328 206.2 3.1e-53 NP_001238919 (OMIM: 602842,616835) geminin [Homo s ( 209) 1328 206.2 3.1e-53 NP_001238920 (OMIM: 602842,616835) geminin [Homo s ( 209) 1328 206.2 3.1e-53 XP_005249216 (OMIM: 602842,616835) PREDICTED: gemi ( 209) 1328 206.2 3.1e-53 XP_011512953 (OMIM: 602842,616835) PREDICTED: gemi ( 203) 1221 190.5 1.6e-48 XP_016864928 (OMIM: 614086) PREDICTED: multicilin ( 254) 194 39.6 0.0053 NP_001177716 (OMIM: 614086) multicilin [Homo sapie ( 385) 194 39.8 0.0071 >>NP_056979 (OMIM: 602842,616835) geminin [Homo sapiens] (209 aa) initn: 1328 init1: 1328 opt: 1328 Z-score: 1076.8 bits: 206.2 E(85289): 3.1e-53 Smith-Waterman score: 1328; 100.0% identity (100.0% similar) in 209 aa overlap (1-209:1-209) 10 20 30 40 50 60 pF1KB6 MNPSMKQKQEEIKENIKNSSVPRRTLKMIQPSASGSLVGRENELSAGLSKRKHRNDHLTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 MNPSMKQKQEEIKENIKNSSVPRRTLKMIQPSASGSLVGRENELSAGLSKRKHRNDHLTS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 TTSSPGVIVPESSENKNLGGVTQESFDLMIKENPSSQYWKEVAEKRRKALYEALKENEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 TTSSPGVIVPESSENKNLGGVTQESFDLMIKENPSSQYWKEVAEKRRKALYEALKENEKL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 HKEIEQKDNEIARLKKENKELAEVAEHVQYMAELIERLNGEPLDNFESLDNQEFDSEEET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_056 HKEIEQKDNEIARLKKENKELAEVAEHVQYMAELIERLNGEPLDNFESLDNQEFDSEEET 130 140 150 160 170 180 190 200 pF1KB6 VEDSLVEDSEIGTCAEGTVSSSTDAKPCI ::::::::::::::::::::::::::::: NP_056 VEDSLVEDSEIGTCAEGTVSSSTDAKPCI 190 200 >>NP_001238918 (OMIM: 602842,616835) geminin [Homo sapie (209 aa) initn: 1328 init1: 1328 opt: 1328 Z-score: 1076.8 bits: 206.2 E(85289): 3.1e-53 Smith-Waterman score: 1328; 100.0% identity (100.0% similar) in 209 aa overlap (1-209:1-209) 10 20 30 40 50 60 pF1KB6 MNPSMKQKQEEIKENIKNSSVPRRTLKMIQPSASGSLVGRENELSAGLSKRKHRNDHLTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNPSMKQKQEEIKENIKNSSVPRRTLKMIQPSASGSLVGRENELSAGLSKRKHRNDHLTS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 TTSSPGVIVPESSENKNLGGVTQESFDLMIKENPSSQYWKEVAEKRRKALYEALKENEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TTSSPGVIVPESSENKNLGGVTQESFDLMIKENPSSQYWKEVAEKRRKALYEALKENEKL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 HKEIEQKDNEIARLKKENKELAEVAEHVQYMAELIERLNGEPLDNFESLDNQEFDSEEET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HKEIEQKDNEIARLKKENKELAEVAEHVQYMAELIERLNGEPLDNFESLDNQEFDSEEET 130 140 150 160 170 180 190 200 pF1KB6 VEDSLVEDSEIGTCAEGTVSSSTDAKPCI ::::::::::::::::::::::::::::: NP_001 VEDSLVEDSEIGTCAEGTVSSSTDAKPCI 190 200 >>NP_001238919 (OMIM: 602842,616835) geminin [Homo sapie (209 aa) initn: 1328 init1: 1328 opt: 1328 Z-score: 1076.8 bits: 206.2 E(85289): 3.1e-53 Smith-Waterman score: 1328; 100.0% identity (100.0% similar) in 209 aa overlap (1-209:1-209) 10 20 30 40 50 60 pF1KB6 MNPSMKQKQEEIKENIKNSSVPRRTLKMIQPSASGSLVGRENELSAGLSKRKHRNDHLTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNPSMKQKQEEIKENIKNSSVPRRTLKMIQPSASGSLVGRENELSAGLSKRKHRNDHLTS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 TTSSPGVIVPESSENKNLGGVTQESFDLMIKENPSSQYWKEVAEKRRKALYEALKENEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TTSSPGVIVPESSENKNLGGVTQESFDLMIKENPSSQYWKEVAEKRRKALYEALKENEKL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 HKEIEQKDNEIARLKKENKELAEVAEHVQYMAELIERLNGEPLDNFESLDNQEFDSEEET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HKEIEQKDNEIARLKKENKELAEVAEHVQYMAELIERLNGEPLDNFESLDNQEFDSEEET 130 140 150 160 170 180 190 200 pF1KB6 VEDSLVEDSEIGTCAEGTVSSSTDAKPCI ::::::::::::::::::::::::::::: NP_001 VEDSLVEDSEIGTCAEGTVSSSTDAKPCI 190 200 >>NP_001238920 (OMIM: 602842,616835) geminin [Homo sapie (209 aa) initn: 1328 init1: 1328 opt: 1328 Z-score: 1076.8 bits: 206.2 E(85289): 3.1e-53 Smith-Waterman score: 1328; 100.0% identity (100.0% similar) in 209 aa overlap (1-209:1-209) 10 20 30 40 50 60 pF1KB6 MNPSMKQKQEEIKENIKNSSVPRRTLKMIQPSASGSLVGRENELSAGLSKRKHRNDHLTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNPSMKQKQEEIKENIKNSSVPRRTLKMIQPSASGSLVGRENELSAGLSKRKHRNDHLTS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 TTSSPGVIVPESSENKNLGGVTQESFDLMIKENPSSQYWKEVAEKRRKALYEALKENEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TTSSPGVIVPESSENKNLGGVTQESFDLMIKENPSSQYWKEVAEKRRKALYEALKENEKL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 HKEIEQKDNEIARLKKENKELAEVAEHVQYMAELIERLNGEPLDNFESLDNQEFDSEEET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HKEIEQKDNEIARLKKENKELAEVAEHVQYMAELIERLNGEPLDNFESLDNQEFDSEEET 130 140 150 160 170 180 190 200 pF1KB6 VEDSLVEDSEIGTCAEGTVSSSTDAKPCI ::::::::::::::::::::::::::::: NP_001 VEDSLVEDSEIGTCAEGTVSSSTDAKPCI 190 200 >>XP_005249216 (OMIM: 602842,616835) PREDICTED: geminin (209 aa) initn: 1328 init1: 1328 opt: 1328 Z-score: 1076.8 bits: 206.2 E(85289): 3.1e-53 Smith-Waterman score: 1328; 100.0% identity (100.0% similar) in 209 aa overlap (1-209:1-209) 10 20 30 40 50 60 pF1KB6 MNPSMKQKQEEIKENIKNSSVPRRTLKMIQPSASGSLVGRENELSAGLSKRKHRNDHLTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MNPSMKQKQEEIKENIKNSSVPRRTLKMIQPSASGSLVGRENELSAGLSKRKHRNDHLTS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 TTSSPGVIVPESSENKNLGGVTQESFDLMIKENPSSQYWKEVAEKRRKALYEALKENEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TTSSPGVIVPESSENKNLGGVTQESFDLMIKENPSSQYWKEVAEKRRKALYEALKENEKL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 HKEIEQKDNEIARLKKENKELAEVAEHVQYMAELIERLNGEPLDNFESLDNQEFDSEEET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HKEIEQKDNEIARLKKENKELAEVAEHVQYMAELIERLNGEPLDNFESLDNQEFDSEEET 130 140 150 160 170 180 190 200 pF1KB6 VEDSLVEDSEIGTCAEGTVSSSTDAKPCI ::::::::::::::::::::::::::::: XP_005 VEDSLVEDSEIGTCAEGTVSSSTDAKPCI 190 200 >>XP_011512953 (OMIM: 602842,616835) PREDICTED: geminin (203 aa) initn: 1221 init1: 1221 opt: 1221 Z-score: 992.0 bits: 190.5 E(85289): 1.6e-48 Smith-Waterman score: 1221; 99.5% identity (100.0% similar) in 193 aa overlap (17-209:11-203) 10 20 30 40 50 60 pF1KB6 MNPSMKQKQEEIKENIKNSSVPRRTLKMIQPSASGSLVGRENELSAGLSKRKHRNDHLTS .::::::::::::::::::::::::::::::::::::::::::: XP_011 MGLKQNCFYYQNSSVPRRTLKMIQPSASGSLVGRENELSAGLSKRKHRNDHLTS 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 TTSSPGVIVPESSENKNLGGVTQESFDLMIKENPSSQYWKEVAEKRRKALYEALKENEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TTSSPGVIVPESSENKNLGGVTQESFDLMIKENPSSQYWKEVAEKRRKALYEALKENEKL 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 HKEIEQKDNEIARLKKENKELAEVAEHVQYMAELIERLNGEPLDNFESLDNQEFDSEEET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 HKEIEQKDNEIARLKKENKELAEVAEHVQYMAELIERLNGEPLDNFESLDNQEFDSEEET 120 130 140 150 160 170 190 200 pF1KB6 VEDSLVEDSEIGTCAEGTVSSSTDAKPCI ::::::::::::::::::::::::::::: XP_011 VEDSLVEDSEIGTCAEGTVSSSTDAKPCI 180 190 200 >>XP_016864928 (OMIM: 614086) PREDICTED: multicilin isof (254 aa) initn: 194 init1: 194 opt: 194 Z-score: 174.9 bits: 39.6 E(85289): 0.0053 Smith-Waterman score: 194; 44.6% identity (80.0% similar) in 65 aa overlap (94-158:46-110) 70 80 90 100 110 120 pF1KB6 SPGVIVPESSENKNLGGVTQESFDLMIKENPSSQYWKEVAEKRRKALYEALKENEKLHKE : :::::::.. ..:: .:: ::..:: XP_016 CDISPFGPCLSPPLDPRALQSPPLRPPDVPPPEQYWKEVADQNQRALGDALVENNQLHVT 20 30 40 50 60 70 130 140 150 160 170 180 pF1KB6 IEQKDNEIARLKKENKELAEVAEHVQYMAELIERLNGEPLDNFESLDNQEFDSEEETVED . ::..::: ::..: .: :.: .....: ....: XP_016 LTQKQEEIASLKERNVQLKELASRTRHLASVLDKLMITQSRDCGAAAEPFLLKAKAKRSL 80 90 100 110 120 130 190 200 pF1KB6 SLVEDSEIGTCAEGTVSSSTDAKPCI XP_016 EELVSAAGQDCAEVDAILREISERCDEALQSRDPKRPRLLPEPANTDTRPGNLHGAFRGL 140 150 160 170 180 190 >>NP_001177716 (OMIM: 614086) multicilin [Homo sapiens] (385 aa) initn: 222 init1: 194 opt: 194 Z-score: 172.6 bits: 39.8 E(85289): 0.0071 Smith-Waterman score: 194; 44.6% identity (80.0% similar) in 65 aa overlap (94-158:177-241) 70 80 90 100 110 120 pF1KB6 SPGVIVPESSENKNLGGVTQESFDLMIKENPSSQYWKEVAEKRRKALYEALKENEKLHKE : :::::::.. ..:: .:: ::..:: NP_001 CDISPFGPCLSPPLDPRALQSPPLRPPDVPPPEQYWKEVADQNQRALGDALVENNQLHVT 150 160 170 180 190 200 130 140 150 160 170 180 pF1KB6 IEQKDNEIARLKKENKELAEVAEHVQYMAELIERLNGEPLDNFESLDNQEFDSEEETVED . ::..::: ::..: .: :.: .....: ....: NP_001 LTQKQEEIASLKERNVQLKELASRTRHLASVLDKLMITQSRDCGAAAEPFLLKAKAKRSL 210 220 230 240 250 260 190 200 pF1KB6 SLVEDSEIGTCAEGTVSSSTDAKPCI NP_001 EELVSAAGQDCAEVDAILREISERCDEALQSRDPKRPRLLPEPANTDTRPGNLHGAFRGL 270 280 290 300 310 320 209 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 11:39:29 2016 done: Fri Nov 4 11:39:30 2016 Total Scan time: 5.060 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]