Result of FASTA (omim) for
pF1KB6942
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6942, 229 aa
1>>>pF1KB6942 229 - 229 aa - 229 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.9689+/-0.00032; mu= 9.1039+/- 0.020
mean_var=148.7959+/-29.657, 0's: 0 Z-trim(121.5): 16 B-trim: 811 in 1/53
Lambda= 0.105143
statistics sampled from 38272 (38288) to 38272 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.776), E-opt: 0.2 (0.449), width: 16
Scan time: 6.500
The best scores are: opt bits E(85289)
NP_009028 (OMIM: 118970) clathrin light chain B is ( 229) 1515 240.4 2e-63
NP_001825 (OMIM: 118970) clathrin light chain B is ( 211) 1050 169.8 3.2e-42
NP_001070145 (OMIM: 118960) clathrin light chain A ( 236) 927 151.2 1.4e-36
NP_001171689 (OMIM: 118960) clathrin light chain A ( 230) 790 130.4 2.5e-30
NP_009027 (OMIM: 118960) clathrin light chain A is ( 248) 648 108.9 8.2e-24
XP_016869747 (OMIM: 118960) PREDICTED: clathrin li ( 152) 618 104.1 1.3e-22
XP_016864515 (OMIM: 118970) PREDICTED: clathrin li ( 144) 604 102.0 5.6e-22
NP_001824 (OMIM: 118960) clathrin light chain A is ( 218) 576 97.9 1.4e-20
NP_001171690 (OMIM: 118960) clathrin light chain A ( 168) 544 92.9 3.5e-19
XP_016864516 (OMIM: 118970) PREDICTED: clathrin li ( 134) 519 89.1 4.1e-18
XP_016869746 (OMIM: 118960) PREDICTED: clathrin li ( 170) 476 82.6 4.4e-16
NP_001298132 (OMIM: 118960) clathrin light chain A ( 140) 404 71.6 7.5e-13
NP_001298134 (OMIM: 118960) clathrin light chain A ( 178) 397 70.7 1.9e-12
NP_001298133 (OMIM: 118960) clathrin light chain A ( 196) 355 64.3 1.6e-10
NP_001298135 (OMIM: 118960) clathrin light chain A ( 101) 285 53.5 1.6e-07
NP_001171691 (OMIM: 118960) clathrin light chain A ( 166) 285 53.6 2.3e-07
>>NP_009028 (OMIM: 118970) clathrin light chain B isofor (229 aa)
initn: 1515 init1: 1515 opt: 1515 Z-score: 1259.7 bits: 240.4 E(85289): 2e-63
Smith-Waterman score: 1515; 100.0% identity (100.0% similar) in 229 aa overlap (1-229:1-229)
10 20 30 40 50 60
pF1KB6 MADDFGFFSSSESGAPEAAEEDPAAAFLAQQESEIAGIENDEGFGAPAGSHAAPAQPGPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MADDFGFFSSSESGAPEAAEEDPAAAFLAQQESEIAGIENDEGFGAPAGSHAAPAQPGPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 SGAGSEDMGTTVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRKRLQELDAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SGAGSEDMGTTVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRKRLQELDAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 SKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNRIADKAFYQQPDADIIGYVASEEAFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNRIADKAFYQQPDADIIGYVASEEAFV
130 140 150 160 170 180
190 200 210 220
pF1KB6 KESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLRSVLMSLKQTPLSR
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 KESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLRSVLMSLKQTPLSR
190 200 210 220
>>NP_001825 (OMIM: 118970) clathrin light chain B isofor (211 aa)
initn: 1151 init1: 1047 opt: 1050 Z-score: 879.0 bits: 169.8 E(85289): 3.2e-42
Smith-Waterman score: 1348; 92.1% identity (92.1% similar) in 229 aa overlap (1-229:1-211)
10 20 30 40 50 60
pF1KB6 MADDFGFFSSSESGAPEAAEEDPAAAFLAQQESEIAGIENDEGFGAPAGSHAAPAQPGPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MADDFGFFSSSESGAPEAAEEDPAAAFLAQQESEIAGIENDEGFGAPAGSHAAPAQPGPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 SGAGSEDMGTTVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRKRLQELDAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGAGSEDMGTTVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRKRLQELDAA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 SKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNRIADKAFYQQPDADIIGYVASEEAFV
::::::::::::::::::::::::::::::::::: :::::::
NP_001 SKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNR------------------ASEEAFV
130 140 150 160
190 200 210 220
pF1KB6 KESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLRSVLMSLKQTPLSR
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLRSVLMSLKQTPLSR
170 180 190 200 210
>>NP_001070145 (OMIM: 118960) clathrin light chain A iso (236 aa)
initn: 908 init1: 770 opt: 927 Z-score: 777.5 bits: 151.2 E(85289): 1.4e-36
Smith-Waterman score: 927; 64.7% identity (84.2% similar) in 215 aa overlap (13-227:21-234)
10 20 30 40 50
pF1KB6 MADDFGFFSSSESGAPEAAEEDPAAAFLAQQESEIAGIENDEGFGAPAGSHA
.:. :.:::::::::::::::::::::::.:. :.
NP_001 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 APAQPGPTSGAGSEDMGTTVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRK
.: :: .: . . ..::. .::.:::.:.::::.:.::: .:::::::::::: .
NP_001 GP-QPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQME
70 80 90 100 110
120 130 140 150 160 170
pF1KB6 RLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNRIADKAFYQQPDADIIGY
::. ::: :. : ::.::: :.:::: ::.::..:.: :::.::.:::.:: ::.:::
NP_001 RLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGY
120 130 140 150 160 170
180 190 200 210 220
pF1KB6 VASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLRSVLMSLKQTPLSR
::.:::::.. : .::::::.::.::::::::::: :::::.::::.::::.::
NP_001 VAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLISLKQAPLVH
180 190 200 210 220 230
>>NP_001171689 (OMIM: 118960) clathrin light chain A iso (230 aa)
initn: 791 init1: 387 opt: 790 Z-score: 665.4 bits: 130.4 E(85289): 2.5e-30
Smith-Waterman score: 790; 58.6% identity (78.1% similar) in 215 aa overlap (13-227:21-228)
10 20 30 40 50
pF1KB6 MADDFGFFSSSESGAPEAAEEDPAAAFLAQQESEIAGIENDEGFGAPAGSHA
.:. :.:::::::::::::::::::::::.:. :.
NP_001 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 APAQPGPTSGAGSEDMGTTVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRK
.: :: .: . . ..::. .::.:::.:.::::.:.::: .:::::::::::: .
NP_001 GP-QPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQME
70 80 90 100 110
120 130 140 150 160 170
pF1KB6 RLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNRIADKAFYQQPDADIIGY
::. ::: :. : ::.::: :.:::: ::.::..:.: :: ..: ..
NP_001 RLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNSTN----INHPCYSL--E
120 130 140 150 160 170
180 190 200 210 220
pF1KB6 VASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLRSVLMSLKQTPLSR
:.:::::.. : .::::::.::.::::::::::: :::::.::::.::::.::
NP_001 QAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLISLKQAPLVH
180 190 200 210 220 230
>>NP_009027 (OMIM: 118960) clathrin light chain A isofor (248 aa)
initn: 920 init1: 490 opt: 648 Z-score: 548.5 bits: 108.9 E(85289): 8.2e-24
Smith-Waterman score: 893; 61.2% identity (79.7% similar) in 227 aa overlap (13-227:21-246)
10 20 30 40 50
pF1KB6 MADDFGFFSSSESGAPEAAEEDPAAAFLAQQESEIAGIENDEGFGAPAGSHA
.:. :.:::::::::::::::::::::::.:. :.
NP_009 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 APAQPGPTSGAGSEDMGTTVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRK
.: :: .: . . ..::. .::.:::.:.::::.:.::: .:::::::::::: .
NP_009 GP-QPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQME
70 80 90 100 110
120 130 140 150 160 170
pF1KB6 RLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNRIADKAFYQQPDADIIGY
::. ::: :. : ::.::: :.:::: ::.::..:.: :::.::.:::.:: ::.:::
NP_009 RLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNRVADEAFYKQPFADVIGY
120 130 140 150 160 170
180 190 200 210 220
pF1KB6 V------------ASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLRSVLM
: :.:::::.. : .::::::.::.::::::::::: :::::.::::.
NP_009 VTNINHPCYSLEQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLI
180 190 200 210 220 230
pF1KB6 SLKQTPLSR
::::.::
NP_009 SLKQAPLVH
240
>>XP_016869747 (OMIM: 118960) PREDICTED: clathrin light (152 aa)
initn: 638 init1: 372 opt: 618 Z-score: 526.7 bits: 104.1 E(85289): 1.3e-22
Smith-Waterman score: 618; 60.9% identity (80.8% similar) in 156 aa overlap (72-227:1-150)
50 60 70 80 90 100
pF1KB6 EGFGAPAGSHAAPAQPGPTSGAGSEDMGTTVNGDVFQEANGPADGYAAIAQADRLTQEPE
.::. .::.:::.:.::::.:.::: .:::
XP_016 MNGEYYQESNGPTDSYAAISQVDRLQSEPE
10 20 30
110 120 130 140 150 160
pF1KB6 SIRKWREEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNRIADKAF
::::::::: .::. ::: :. : ::.::: :.:::: ::.::..:.: ::
XP_016 SIRKWREEQMERLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNSTN----
40 50 60 70 80
170 180 190 200 210 220
pF1KB6 YQQPDADIIGYVASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLRSVLMS
..: .. :.:::::.. : .::::::.::.::::::::::: :::::.::::.:
XP_016 INHPCYSL--EQAAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLIS
90 100 110 120 130 140
pF1KB6 LKQTPLSR
:::.::
XP_016 LKQAPLVH
150
>>XP_016864515 (OMIM: 118970) PREDICTED: clathrin light (144 aa)
initn: 684 init1: 601 opt: 604 Z-score: 515.5 bits: 102.0 E(85289): 5.6e-22
Smith-Waterman score: 902; 88.9% identity (88.9% similar) in 162 aa overlap (68-229:1-144)
40 50 60 70 80 90
pF1KB6 IENDEGFGAPAGSHAAPAQPGPTSGAGSEDMGTTVNGDVFQEANGPADGYAAIAQADRLT
::::::::::::::::::::::::::::::
XP_016 MGTTVNGDVFQEANGPADGYAAIAQADRLT
10 20 30
100 110 120 130 140 150
pF1KB6 QEPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNRIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNR--
40 50 60 70 80
160 170 180 190 200 210
pF1KB6 DKAFYQQPDADIIGYVASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLRS
::::::::::::::::::::::::::::::::::::::::::::
XP_016 ----------------ASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLRS
90 100 110 120 130
220
pF1KB6 VLMSLKQTPLSR
::::::::::::
XP_016 VLMSLKQTPLSR
140
>>NP_001824 (OMIM: 118960) clathrin light chain A isofor (218 aa)
initn: 597 init1: 417 opt: 576 Z-score: 490.2 bits: 97.9 E(85289): 1.4e-20
Smith-Waterman score: 785; 58.6% identity (76.3% similar) in 215 aa overlap (13-227:21-216)
10 20 30 40 50
pF1KB6 MADDFGFFSSSESGAPEAAEEDPAAAFLAQQESEIAGIENDEGFGAPAGSHA
.:. :.:::::::::::::::::::::::.:. :.
NP_001 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 APAQPGPTSGAGSEDMGTTVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRK
.: :: .: . . ..::. .::.:::.:.::::.:.::: .:::::::::::: .
NP_001 GP-QPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQME
70 80 90 100 110
120 130 140 150 160 170
pF1KB6 RLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNRIADKAFYQQPDADIIGY
::. ::: :. : ::.::: :.:::: ::.::..:.: :::
NP_001 RLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNR-----------------
120 130 140 150 160
180 190 200 210 220
pF1KB6 VASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLRSVLMSLKQTPLSR
:.:::::.. : .::::::.::.::::::::::: :::::.::::.::::.::
NP_001 -AAEEAFVNDIDESSPGTEWERVARLCDFNPKSSKQAKDVSRMRSVLISLKQAPLVH
170 180 190 200 210
>>NP_001171690 (OMIM: 118960) clathrin light chain A iso (168 aa)
initn: 525 init1: 387 opt: 544 Z-score: 465.5 bits: 92.9 E(85289): 3.5e-19
Smith-Waterman score: 544; 59.2% identity (79.6% similar) in 142 aa overlap (13-154:21-161)
10 20 30 40 50
pF1KB6 MADDFGFFSSSESGAPEAAEEDPAAAFLAQQESEIAGIENDEGFGAPAGSHA
.:. :.:::::::::::::::::::::::.:. :.
NP_001 MAELDPFGAPAGAPGGPALGNGVAGAGEEDPAAAFLAQQESEIAGIENDEAFAILDGGAP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 APAQPGPTSGAGSEDMGTTVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRK
.: :: .: . . ..::. .::.:::.:.::::.:.::: .:::::::::::: .
NP_001 GP-QPHGEPPGGPDAVDGVMNGEYYQESNGPTDSYAAISQVDRLQSEPESIRKWREEQME
70 80 90 100 110
120 130 140 150 160 170
pF1KB6 RLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNRIADKAFYQQPDADIIGY
::. ::: :. : ::.::: :.:::: ::.::..:.: ::
NP_001 RLEALDANSRKQEAEWKEKAIKELEEWYARQDEQLQKTKANNSRRSLCK
120 130 140 150 160
180 190 200 210 220
pF1KB6 VASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLRSVLMSLKQTPLSR
>>XP_016864516 (OMIM: 118970) PREDICTED: clathrin light (134 aa)
initn: 519 init1: 519 opt: 519 Z-score: 446.3 bits: 89.1 E(85289): 4.1e-18
Smith-Waterman score: 519; 100.0% identity (100.0% similar) in 78 aa overlap (1-78:1-78)
10 20 30 40 50 60
pF1KB6 MADDFGFFSSSESGAPEAAEEDPAAAFLAQQESEIAGIENDEGFGAPAGSHAAPAQPGPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MADDFGFFSSSESGAPEAAEEDPAAAFLAQQESEIAGIENDEGFGAPAGSHAAPAQPGPT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 SGAGSEDMGTTVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRKRLQELDAA
::::::::::::::::::
XP_016 SGAGSEDMGTTVNGDVFQPVHHQRVQLQTQLPIQPKDEPAHNYSSSIWHSQGQGQKGPAG
70 80 90 100 110 120
229 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 11:38:11 2016 done: Fri Nov 4 11:38:12 2016
Total Scan time: 6.500 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]