FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6951, 212 aa 1>>>pF1KB6951 212 - 212 aa - 212 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.0574+/-0.000358; mu= 14.8440+/- 0.022 mean_var=59.7030+/-11.518, 0's: 0 Z-trim(114.1): 20 B-trim: 36 in 1/54 Lambda= 0.165988 statistics sampled from 23806 (23826) to 23806 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.684), E-opt: 0.2 (0.279), width: 16 Scan time: 4.150 The best scores are: opt bits E(85289) NP_060048 (OMIM: 611757) ropporin-1A isoform a [Ho ( 212) 1400 343.3 1.7e-94 XP_011511235 (OMIM: 611757) PREDICTED: ropporin-1A ( 212) 1400 343.3 1.7e-94 XP_011511236 (OMIM: 611757) PREDICTED: ropporin-1A ( 212) 1400 343.3 1.7e-94 NP_001304703 (OMIM: 611757) ropporin-1A isoform a ( 212) 1400 343.3 1.7e-94 NP_001304704 (OMIM: 611757) ropporin-1A isoform b ( 120) 796 198.6 3.6e-51 NP_001188395 (OMIM: 611756) ropporin-1-like protei ( 230) 540 137.4 1.8e-32 NP_114122 (OMIM: 611756) ropporin-1-like protein [ ( 230) 540 137.4 1.8e-32 XP_016865436 (OMIM: 611756) PREDICTED: ropporin-1- ( 220) 522 133.1 3.4e-31 XP_006714566 (OMIM: 611756) PREDICTED: ropporin-1- ( 257) 522 133.1 3.9e-31 XP_006714567 (OMIM: 611756) PREDICTED: ropporin-1- ( 257) 522 133.1 3.9e-31 XP_016865435 (OMIM: 611756) PREDICTED: ropporin-1- ( 232) 521 132.9 4.2e-31 >>NP_060048 (OMIM: 611757) ropporin-1A isoform a [Homo s (212 aa) initn: 1400 init1: 1400 opt: 1400 Z-score: 1817.6 bits: 343.3 E(85289): 1.7e-94 Smith-Waterman score: 1400; 100.0% identity (100.0% similar) in 212 aa overlap (1-212:1-212) 10 20 30 40 50 60 pF1KB6 MAQTDKPTCIPPELPKMLKEFAKAAIRVQPQDLIQWAADYFEALSRGETPPVRERSERVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MAQTDKPTCIPPELPKMLKEFAKAAIRVQPQDLIQWAADYFEALSRGETPPVRERSERVA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LCNRAELTPELLKILHSQVAGRLIIRAEELAQMWKVVNLPTDLFNSVMNVGRFTEEIEWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 LCNRAELTPELLKILHSQVAGRLIIRAEELAQMWKVVNLPTDLFNSVMNVGRFTEEIEWL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 KFLALACSALGVTITKTLKIVCEVLSCDHNGGSPRIPFSTFQFLYTYIAKVDGEISASHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 KFLALACSALGVTITKTLKIVCEVLSCDHNGGSPRIPFSTFQFLYTYIAKVDGEISASHV 130 140 150 160 170 180 190 200 210 pF1KB6 SRMLNYMEQEVIGPDGIITVNDFTQNPRVQLE :::::::::::::::::::::::::::::::: NP_060 SRMLNYMEQEVIGPDGIITVNDFTQNPRVQLE 190 200 210 >>XP_011511235 (OMIM: 611757) PREDICTED: ropporin-1A iso (212 aa) initn: 1400 init1: 1400 opt: 1400 Z-score: 1817.6 bits: 343.3 E(85289): 1.7e-94 Smith-Waterman score: 1400; 100.0% identity (100.0% similar) in 212 aa overlap (1-212:1-212) 10 20 30 40 50 60 pF1KB6 MAQTDKPTCIPPELPKMLKEFAKAAIRVQPQDLIQWAADYFEALSRGETPPVRERSERVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAQTDKPTCIPPELPKMLKEFAKAAIRVQPQDLIQWAADYFEALSRGETPPVRERSERVA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LCNRAELTPELLKILHSQVAGRLIIRAEELAQMWKVVNLPTDLFNSVMNVGRFTEEIEWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LCNRAELTPELLKILHSQVAGRLIIRAEELAQMWKVVNLPTDLFNSVMNVGRFTEEIEWL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 KFLALACSALGVTITKTLKIVCEVLSCDHNGGSPRIPFSTFQFLYTYIAKVDGEISASHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KFLALACSALGVTITKTLKIVCEVLSCDHNGGSPRIPFSTFQFLYTYIAKVDGEISASHV 130 140 150 160 170 180 190 200 210 pF1KB6 SRMLNYMEQEVIGPDGIITVNDFTQNPRVQLE :::::::::::::::::::::::::::::::: XP_011 SRMLNYMEQEVIGPDGIITVNDFTQNPRVQLE 190 200 210 >>XP_011511236 (OMIM: 611757) PREDICTED: ropporin-1A iso (212 aa) initn: 1400 init1: 1400 opt: 1400 Z-score: 1817.6 bits: 343.3 E(85289): 1.7e-94 Smith-Waterman score: 1400; 100.0% identity (100.0% similar) in 212 aa overlap (1-212:1-212) 10 20 30 40 50 60 pF1KB6 MAQTDKPTCIPPELPKMLKEFAKAAIRVQPQDLIQWAADYFEALSRGETPPVRERSERVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MAQTDKPTCIPPELPKMLKEFAKAAIRVQPQDLIQWAADYFEALSRGETPPVRERSERVA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LCNRAELTPELLKILHSQVAGRLIIRAEELAQMWKVVNLPTDLFNSVMNVGRFTEEIEWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LCNRAELTPELLKILHSQVAGRLIIRAEELAQMWKVVNLPTDLFNSVMNVGRFTEEIEWL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 KFLALACSALGVTITKTLKIVCEVLSCDHNGGSPRIPFSTFQFLYTYIAKVDGEISASHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KFLALACSALGVTITKTLKIVCEVLSCDHNGGSPRIPFSTFQFLYTYIAKVDGEISASHV 130 140 150 160 170 180 190 200 210 pF1KB6 SRMLNYMEQEVIGPDGIITVNDFTQNPRVQLE :::::::::::::::::::::::::::::::: XP_011 SRMLNYMEQEVIGPDGIITVNDFTQNPRVQLE 190 200 210 >>NP_001304703 (OMIM: 611757) ropporin-1A isoform a [Hom (212 aa) initn: 1400 init1: 1400 opt: 1400 Z-score: 1817.6 bits: 343.3 E(85289): 1.7e-94 Smith-Waterman score: 1400; 100.0% identity (100.0% similar) in 212 aa overlap (1-212:1-212) 10 20 30 40 50 60 pF1KB6 MAQTDKPTCIPPELPKMLKEFAKAAIRVQPQDLIQWAADYFEALSRGETPPVRERSERVA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MAQTDKPTCIPPELPKMLKEFAKAAIRVQPQDLIQWAADYFEALSRGETPPVRERSERVA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LCNRAELTPELLKILHSQVAGRLIIRAEELAQMWKVVNLPTDLFNSVMNVGRFTEEIEWL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LCNRAELTPELLKILHSQVAGRLIIRAEELAQMWKVVNLPTDLFNSVMNVGRFTEEIEWL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 KFLALACSALGVTITKTLKIVCEVLSCDHNGGSPRIPFSTFQFLYTYIAKVDGEISASHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KFLALACSALGVTITKTLKIVCEVLSCDHNGGSPRIPFSTFQFLYTYIAKVDGEISASHV 130 140 150 160 170 180 190 200 210 pF1KB6 SRMLNYMEQEVIGPDGIITVNDFTQNPRVQLE :::::::::::::::::::::::::::::::: NP_001 SRMLNYMEQEVIGPDGIITVNDFTQNPRVQLE 190 200 210 >>NP_001304704 (OMIM: 611757) ropporin-1A isoform b [Hom (120 aa) initn: 796 init1: 796 opt: 796 Z-score: 1039.6 bits: 198.6 E(85289): 3.6e-51 Smith-Waterman score: 796; 100.0% identity (100.0% similar) in 120 aa overlap (93-212:1-120) 70 80 90 100 110 120 pF1KB6 NRAELTPELLKILHSQVAGRLIIRAEELAQMWKVVNLPTDLFNSVMNVGRFTEEIEWLKF :::::::::::::::::::::::::::::: NP_001 MWKVVNLPTDLFNSVMNVGRFTEEIEWLKF 10 20 30 130 140 150 160 170 180 pF1KB6 LALACSALGVTITKTLKIVCEVLSCDHNGGSPRIPFSTFQFLYTYIAKVDGEISASHVSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LALACSALGVTITKTLKIVCEVLSCDHNGGSPRIPFSTFQFLYTYIAKVDGEISASHVSR 40 50 60 70 80 90 190 200 210 pF1KB6 MLNYMEQEVIGPDGIITVNDFTQNPRVQLE :::::::::::::::::::::::::::::: NP_001 MLNYMEQEVIGPDGIITVNDFTQNPRVQLE 100 110 120 >>NP_001188395 (OMIM: 611756) ropporin-1-like protein [H (230 aa) initn: 540 init1: 314 opt: 540 Z-score: 704.0 bits: 137.4 E(85289): 1.8e-32 Smith-Waterman score: 540; 39.8% identity (72.3% similar) in 206 aa overlap (10-212:15-220) 10 20 30 40 50 pF1KB6 MAQTDKPTCIPPELPKMLKEFAKAAIRVQPQDLIQWAADYFEALSRGETPPVRER :::::: .::.:.:::::.:: :...:.: :: :::::. ::..: NP_001 MPLPDTMFCAQQIHIPPELPDILKQFTKAAIRTQPADVLRWSAGYFSALSRGDPLPVKDR 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 SERVALCNRAE--LTPELLKILHSQVAGRLIIRAEELAQMWKVVNLPTDLFNSVMNVGRF : . .... :: :::.::.: . .. .: : :: . :: . :...... NP_001 MEMPTATQKTDTGLTQGLLKVLHKQCHHKRYVELTDLEQKWKNLCLPKEKFKALLQLDPC 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 TEEIEWLKFLALACSALGVTITKTLKIVCEVLSCDHNGGSPRIPFSTFQFLYTYIAKVDG ..:.:..::::.:: :: ... .:: .::.:. : .:: ::::.::...: :.:..:. NP_001 ENKIKWINFLALGCSMLGGSLNTALKHLCEILTDDPEGGPARIPFKTFSYVYRYLARLDS 130 140 150 160 170 180 180 190 200 210 pF1KB6 EISASHVSRMLNYMEQEVIG-PDGIITVNDFTQNPRVQLE ..: .. .: ..... . .:.: ..:: : :: NP_001 DVSPLETESYLASLKENIDARKNGMIGLSDFFFPKRKLLESIENSEDVGH 190 200 210 220 230 >>NP_114122 (OMIM: 611756) ropporin-1-like protein [Homo (230 aa) initn: 540 init1: 314 opt: 540 Z-score: 704.0 bits: 137.4 E(85289): 1.8e-32 Smith-Waterman score: 540; 39.8% identity (72.3% similar) in 206 aa overlap (10-212:15-220) 10 20 30 40 50 pF1KB6 MAQTDKPTCIPPELPKMLKEFAKAAIRVQPQDLIQWAADYFEALSRGETPPVRER :::::: .::.:.:::::.:: :...:.: :: :::::. ::..: NP_114 MPLPDTMFCAQQIHIPPELPDILKQFTKAAIRTQPADVLRWSAGYFSALSRGDPLPVKDR 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 SERVALCNRAE--LTPELLKILHSQVAGRLIIRAEELAQMWKVVNLPTDLFNSVMNVGRF : . .... :: :::.::.: . .. .: : :: . :: . :...... NP_114 MEMPTATQKTDTGLTQGLLKVLHKQCHHKRYVELTDLEQKWKNLCLPKEKFKALLQLDPC 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 TEEIEWLKFLALACSALGVTITKTLKIVCEVLSCDHNGGSPRIPFSTFQFLYTYIAKVDG ..:.:..::::.:: :: ... .:: .::.:. : .:: ::::.::...: :.:..:. NP_114 ENKIKWINFLALGCSMLGGSLNTALKHLCEILTDDPEGGPARIPFKTFSYVYRYLARLDS 130 140 150 160 170 180 180 190 200 210 pF1KB6 EISASHVSRMLNYMEQEVIG-PDGIITVNDFTQNPRVQLE ..: .. .: ..... . .:.: ..:: : :: NP_114 DVSPLETESYLASLKENIDARKNGMIGLSDFFFPKRKLLESIENSEDVGH 190 200 210 220 230 >>XP_016865436 (OMIM: 611756) PREDICTED: ropporin-1-like (220 aa) initn: 517 init1: 314 opt: 522 Z-score: 681.0 bits: 133.1 E(85289): 3.4e-31 Smith-Waterman score: 522; 41.1% identity (74.6% similar) in 185 aa overlap (10-192:15-199) 10 20 30 40 50 pF1KB6 MAQTDKPTCIPPELPKMLKEFAKAAIRVQPQDLIQWAADYFEALSRGETPPVRER :::::: .::.:.:::::.:: :...:.: :: :::::. ::..: XP_016 MPLPDTMFCAQQIHIPPELPDILKQFTKAAIRTQPADVLRWSAGYFSALSRGDPLPVKDR 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 SERVALCNRAE--LTPELLKILHSQVAGRLIIRAEELAQMWKVVNLPTDLFNSVMNVGRF : . .... :: :::.::.: . .. .: : :: . :: . :...... XP_016 MEMPTATQKTDTGLTQGLLKVLHKQCHHKRYVELTDLEQKWKNLCLPKEKFKALLQLDPC 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 TEEIEWLKFLALACSALGVTITKTLKIVCEVLSCDHNGGSPRIPFSTFQFLYTYIAKVDG ..:.:..::::.:: :: ... .:: .::.:. : .:: ::::.::...: :.:..:. XP_016 ENKIKWINFLALGCSMLGGSLNTALKHLCEILTDDPEGGPARIPFKTFSYVYRYLARLDS 130 140 150 160 170 180 180 190 200 210 pF1KB6 EISASHVSRMLNYMEQEVIGPDGIITVNDFTQNPRVQLE ..: .. .: .....: XP_016 DVSPLETESYLASLKENMIRMGAQAWLRHPTSLVAISEES 190 200 210 220 >>XP_006714566 (OMIM: 611756) PREDICTED: ropporin-1-like (257 aa) initn: 517 init1: 314 opt: 522 Z-score: 680.0 bits: 133.1 E(85289): 3.9e-31 Smith-Waterman score: 522; 41.1% identity (74.6% similar) in 185 aa overlap (10-192:15-199) 10 20 30 40 50 pF1KB6 MAQTDKPTCIPPELPKMLKEFAKAAIRVQPQDLIQWAADYFEALSRGETPPVRER :::::: .::.:.:::::.:: :...:.: :: :::::. ::..: XP_006 MPLPDTMFCAQQIHIPPELPDILKQFTKAAIRTQPADVLRWSAGYFSALSRGDPLPVKDR 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 SERVALCNRAE--LTPELLKILHSQVAGRLIIRAEELAQMWKVVNLPTDLFNSVMNVGRF : . .... :: :::.::.: . .. .: : :: . :: . :...... XP_006 MEMPTATQKTDTGLTQGLLKVLHKQCHHKRYVELTDLEQKWKNLCLPKEKFKALLQLDPC 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 TEEIEWLKFLALACSALGVTITKTLKIVCEVLSCDHNGGSPRIPFSTFQFLYTYIAKVDG ..:.:..::::.:: :: ... .:: .::.:. : .:: ::::.::...: :.:..:. XP_006 ENKIKWINFLALGCSMLGGSLNTALKHLCEILTDDPEGGPARIPFKTFSYVYRYLARLDS 130 140 150 160 170 180 180 190 200 210 pF1KB6 EISASHVSRMLNYMEQEVIGPDGIITVNDFTQNPRVQLE ..: .. .: .....: XP_006 DVSPLETESYLASLKENMIRMGAQAWLRHPTSLGRHHLFASPRLFAASEKTIWNKRRVRP 190 200 210 220 230 240 >>XP_006714567 (OMIM: 611756) PREDICTED: ropporin-1-like (257 aa) initn: 517 init1: 314 opt: 522 Z-score: 680.0 bits: 133.1 E(85289): 3.9e-31 Smith-Waterman score: 522; 41.1% identity (74.6% similar) in 185 aa overlap (10-192:15-199) 10 20 30 40 50 pF1KB6 MAQTDKPTCIPPELPKMLKEFAKAAIRVQPQDLIQWAADYFEALSRGETPPVRER :::::: .::.:.:::::.:: :...:.: :: :::::. ::..: XP_006 MPLPDTMFCAQQIHIPPELPDILKQFTKAAIRTQPADVLRWSAGYFSALSRGDPLPVKDR 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 SERVALCNRAE--LTPELLKILHSQVAGRLIIRAEELAQMWKVVNLPTDLFNSVMNVGRF : . .... :: :::.::.: . .. .: : :: . :: . :...... XP_006 MEMPTATQKTDTGLTQGLLKVLHKQCHHKRYVELTDLEQKWKNLCLPKEKFKALLQLDPC 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 TEEIEWLKFLALACSALGVTITKTLKIVCEVLSCDHNGGSPRIPFSTFQFLYTYIAKVDG ..:.:..::::.:: :: ... .:: .::.:. : .:: ::::.::...: :.:..:. XP_006 ENKIKWINFLALGCSMLGGSLNTALKHLCEILTDDPEGGPARIPFKTFSYVYRYLARLDS 130 140 150 160 170 180 180 190 200 210 pF1KB6 EISASHVSRMLNYMEQEVIGPDGIITVNDFTQNPRVQLE ..: .. .: .....: XP_006 DVSPLETESYLASLKENMIRMGAQAWLRHPTSLGRHHLFASPRLFAASEKTIWNKRRVRP 190 200 210 220 230 240 212 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 11:25:52 2016 done: Fri Nov 4 11:25:53 2016 Total Scan time: 4.150 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]