FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6953, 212 aa
1>>>pF1KB6953 212 - 212 aa - 212 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6141+/-0.000617; mu= 12.8088+/- 0.037
mean_var=75.4872+/-14.985, 0's: 0 Z-trim(112.4): 14 B-trim: 135 in 1/51
Lambda= 0.147617
statistics sampled from 13154 (13166) to 13154 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.776), E-opt: 0.2 (0.404), width: 16
Scan time: 1.640
The best scores are: opt bits E(32554)
CCDS4522.1 EDN1 gene_id:1906|Hs108|chr6 ( 212) 1497 327.3 4.4e-90
CCDS13479.1 EDN3 gene_id:1908|Hs108|chr20 ( 219) 314 75.3 3.2e-14
CCDS13477.1 EDN3 gene_id:1908|Hs108|chr20 ( 238) 314 75.4 3.4e-14
CCDS77597.1 EDN3 gene_id:1908|Hs108|chr20 ( 192) 309 74.2 5.9e-14
CCDS13478.1 EDN3 gene_id:1908|Hs108|chr20 ( 224) 309 74.3 6.7e-14
CCDS462.1 EDN2 gene_id:1907|Hs108|chr1 ( 178) 276 67.2 7.3e-12
>>CCDS4522.1 EDN1 gene_id:1906|Hs108|chr6 (212 aa)
initn: 1497 init1: 1497 opt: 1497 Z-score: 1730.7 bits: 327.3 E(32554): 4.4e-90
Smith-Waterman score: 1497; 100.0% identity (100.0% similar) in 212 aa overlap (1-212:1-212)
10 20 30 40 50 60
pF1KB6 MDYLLMIFSLLFVACQGAPETAVLGAELSAVGENGGEKPTPSPPWRLRRSKRCSCSSLMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MDYLLMIFSLLFVACQGAPETAVLGAELSAVGENGGEKPTPSPPWRLRRSKRCSCSSLMD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 KECVYFCHLDIIWVNTPEHVVPYGLGSPRSKRALENLLPTKATDRENRCQCASQKDKKCW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 KECVYFCHLDIIWVNTPEHVVPYGLGSPRSKRALENLLPTKATDRENRCQCASQKDKKCW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 NFCQAGKELRAEDIMEKDWNNHKKGKDCSKLGKKCIYQQLVRGRKIRRSSEEHLRQTRSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 NFCQAGKELRAEDIMEKDWNNHKKGKDCSKLGKKCIYQQLVRGRKIRRSSEEHLRQTRSE
130 140 150 160 170 180
190 200 210
pF1KB6 TMRNSVKSSFHDPKLKGKPSRERYVTHNRAHW
::::::::::::::::::::::::::::::::
CCDS45 TMRNSVKSSFHDPKLKGKPSRERYVTHNRAHW
190 200 210
>>CCDS13479.1 EDN3 gene_id:1908|Hs108|chr20 (219 aa)
initn: 320 init1: 231 opt: 314 Z-score: 368.9 bits: 75.3 E(32554): 3.2e-14
Smith-Waterman score: 314; 37.6% identity (63.8% similar) in 141 aa overlap (13-146:58-196)
10 20 30 40
pF1KB6 MDYLLMIFSLLFVACQGAPETAVLGAELSAVGENGGEKPTPS
:: : .: . . . : : :. . .
CCDS13 AGRRGVSQAPTAARSEGDCEETVAGPGEETVAGPGEGTVAPTALQGPSPGSPGQEQAAEG
30 40 50 60 70 80
50 60 70 80 90
pF1KB6 PPWRLRRSKRCSCSSLMDKECVYFCHLDIIWVNTPEHVVPYGL----GSPRSKRALENLL
: . .::.::.: . ::::::.:::::::.::::..::::: :: :.::. . :
CCDS13 AP-EHHRSRRCTCFTYKDKECVYYCHLDIIWINTPEQTVPYGLSNYRGSFRGKRS-AGPL
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB6 P--TKATDREN-RCQCASQKDKKCWNFCQAGKELRAEDIMEKDWNNHKKGKDCSKLGKKC
: . . : . :: :... :: : .:: .. ... . .....::
CCDS13 PGNLQLSHRPHLRCACVGRYDKACLHFCTQTLDVSSNSRTAEKTDKEEEGKVRGANRGLC
150 160 170 180 190 200
160 170 180 190 200 210
pF1KB6 IYQQLVRGRKIRRSSEEHLRQTRSETMRNSVKSSFHDPKLKGKPSRERYVTHNRAHW
CCDS13 QRRLKSRTNKASRL
210
>>CCDS13477.1 EDN3 gene_id:1908|Hs108|chr20 (238 aa)
initn: 320 init1: 231 opt: 314 Z-score: 368.4 bits: 75.4 E(32554): 3.4e-14
Smith-Waterman score: 314; 37.6% identity (63.8% similar) in 141 aa overlap (13-146:58-196)
10 20 30 40
pF1KB6 MDYLLMIFSLLFVACQGAPETAVLGAELSAVGENGGEKPTPS
:: : .: . . . : : :. . .
CCDS13 AGRRGVSQAPTAARSEGDCEETVAGPGEETVAGPGEGTVAPTALQGPSPGSPGQEQAAEG
30 40 50 60 70 80
50 60 70 80 90
pF1KB6 PPWRLRRSKRCSCSSLMDKECVYFCHLDIIWVNTPEHVVPYGL----GSPRSKRALENLL
: . .::.::.: . ::::::.:::::::.::::..::::: :: :.::. . :
CCDS13 AP-EHHRSRRCTCFTYKDKECVYYCHLDIIWINTPEQTVPYGLSNYRGSFRGKRS-AGPL
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB6 P--TKATDREN-RCQCASQKDKKCWNFCQAGKELRAEDIMEKDWNNHKKGKDCSKLGKKC
: . . : . :: :... :: : .:: .. ... . .....::
CCDS13 PGNLQLSHRPHLRCACVGRYDKACLHFCTQTLDVSSNSRTAEKTDKEEEGKVEVKDQQSK
150 160 170 180 190 200
160 170 180 190 200 210
pF1KB6 IYQQLVRGRKIRRSSEEHLRQTRSETMRNSVKSSFHDPKLKGKPSRERYVTHNRAHW
CCDS13 QALDLHHPKLMPGSGLALAPSTCPRCLFQEGAP
210 220 230
>>CCDS77597.1 EDN3 gene_id:1908|Hs108|chr20 (192 aa)
initn: 315 init1: 231 opt: 309 Z-score: 364.0 bits: 74.2 E(32554): 5.9e-14
Smith-Waterman score: 309; 43.2% identity (65.3% similar) in 118 aa overlap (13-123:58-173)
10 20 30 40
pF1KB6 MDYLLMIFSLLFVACQGAPETAVLGAELSAVGENGGEKPTPS
:: : .: . . . : : :. . .
CCDS77 AGRRGVSQAPTAARSEGDCEETVAGPGEETVAGPGEGTVAPTALQGPSPGSPGQEQAAEG
30 40 50 60 70 80
50 60 70 80 90
pF1KB6 PPWRLRRSKRCSCSSLMDKECVYFCHLDIIWVNTPEHVVPYGL----GSPRSKRALENLL
: . .::.::.: . ::::::.:::::::.::::..::::: :: :.::. . :
CCDS77 APEH-HRSRRCTCFTYKDKECVYYCHLDIIWINTPEQTVPYGLSNYRGSFRGKRS-AGPL
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB6 P--TKATDREN-RCQCASQKDKKCWNFCQAGKELRAEDIMEKDWNNHKKGKDCSKLGKKC
: . . : . :: :... :: : .::
CCDS77 PGNLQLSHRPHLRCACVGRYDKACLHFCTQTLDVSRLKSRTNKASRL
150 160 170 180 190
>>CCDS13478.1 EDN3 gene_id:1908|Hs108|chr20 (224 aa)
initn: 339 init1: 231 opt: 309 Z-score: 363.0 bits: 74.3 E(32554): 6.7e-14
Smith-Waterman score: 310; 35.5% identity (61.4% similar) in 166 aa overlap (13-159:58-221)
10 20 30 40
pF1KB6 MDYLLMIFSLLFVACQGAPETAVLGAELSAVGENGGEKPTPS
:: : .: . . . : : :. . .
CCDS13 AGRRGVSQAPTAARSEGDCEETVAGPGEETVAGPGEGTVAPTALQGPSPGSPGQEQAAEG
30 40 50 60 70 80
50 60 70 80 90
pF1KB6 PPWRLRRSKRCSCSSLMDKECVYFCHLDIIWVNTPEHVVPYGL----GSPRSKRALENLL
: . .::.::.: . ::::::.:::::::.::::..::::: :: :.::. . :
CCDS13 AP-EHHRSRRCTCFTYKDKECVYYCHLDIIWINTPEQTVPYGLSNYRGSFRGKRS-AGPL
90 100 110 120 130 140
100 110 120 130 140
pF1KB6 P--TKATDREN-RCQCASQKDKKCWNFC----QAGKELRAEDIMEKDWNN--HKKGKDCS
: . . : . :: :... :: : .:: .........: . :. . : : :
CCDS13 PGNLQLSHRPHLRCACVGRYDKACLHFCTQTLDVSRQVEVKDQQSKQALDLHHPKLMPGS
150 160 170 180 190 200
150 160 170 180 190 200
pF1KB6 KLG------KKCIYQQLVRGRKIRRSSEEHLRQTRSETMRNSVKSSFHDPKLKGKPSRER
:. .:..:.
CCDS13 GLALAPSTCPRCLFQEGAP
210 220
>>CCDS462.1 EDN2 gene_id:1907|Hs108|chr1 (178 aa)
initn: 341 init1: 254 opt: 276 Z-score: 326.5 bits: 67.2 E(32554): 7.3e-12
Smith-Waterman score: 323; 39.0% identity (57.3% similar) in 164 aa overlap (49-212:45-175)
20 30 40 50 60 70
pF1KB6 PETAVLGAELSAVGENGGEKPTPSPPWRLRRSKRCSCSSLMDKECVYFCHLDIIWVNTPE
: .:::::: .:::::::::::::::::::
CCDS46 LLVALHEGKGQAAATLEQPASSSHAQGTHLRLRRCSCSSWLDKECVYFCHLDIIWVNTPE
20 30 40 50 60 70
80 90 100 110 120 130
pF1KB6 HVVPYGLGSPRSKRALENLLPTKATDRENRCQCASQKDKKCWNFCQAGKELRAEDIMEKD
...:::::.: .: . :: ::::.: .: : .:: ...
CCDS46 QTAPYGLGNPPRRR--RRSLPR-------RCQCSSARDPACATFC-----------LRRP
80 90 100 110
140 150 160 170 180 190
pF1KB6 WNNHKKGKDCSKLGKKCIYQQLVRGRKIRRSSEEHLRQTRSETMRNSVKSSFHDPKLKGK
:. . : :. . ..: : : .. : :.. :. . .::: : : . .
CCDS46 WT--EAGAVPSRKSPADVFQ---TG-KTGATTGELLQRLRDIS---TVKSLF--AKRQQE
120 130 140 150 160
200 210
pF1KB6 PSRERYVTHNRAHW
:: ::.: :
CCDS46 AMREPRSTHSR--WRKR
170
212 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 11:23:34 2016 done: Fri Nov 4 11:23:35 2016
Total Scan time: 1.640 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]