Result of FASTA (omim) for
pF1KB6953
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6953, 212 aa
1>>>pF1KB6953 212 - 212 aa - 212 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6319+/-0.000292; mu= 12.6077+/- 0.018
mean_var=77.5835+/-15.988, 0's: 0 Z-trim(119.4): 26 B-trim: 1708 in 2/50
Lambda= 0.145609
statistics sampled from 33371 (33408) to 33371 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.763), E-opt: 0.2 (0.392), width: 16
Scan time: 5.660
The best scores are: opt bits E(85289)
NP_001946 (OMIM: 131240,612798,615706) endothelin- ( 212) 1497 323.1 2.1e-88
XP_016865820 (OMIM: 131240,612798,615706) PREDICTE ( 212) 1497 323.1 2.1e-88
XP_011512632 (OMIM: 131240,612798,615706) PREDICTE ( 212) 1497 323.1 2.1e-88
XP_011512633 (OMIM: 131240,612798,615706) PREDICTE ( 212) 1497 323.1 2.1e-88
NP_001161791 (OMIM: 131240,612798,615706) endothel ( 211) 1480 319.6 2.4e-87
XP_011512634 (OMIM: 131240,612798,615706) PREDICTE ( 211) 1480 319.6 2.4e-87
XP_005260369 (OMIM: 131242,209880,613265,613712) P ( 251) 317 75.3 9.8e-14
NP_001289384 (OMIM: 131242,209880,613265,613712) e ( 198) 314 74.6 1.3e-13
XP_006723797 (OMIM: 131242,209880,613265,613712) P ( 208) 314 74.6 1.3e-13
NP_996915 (OMIM: 131242,209880,613265,613712) endo ( 219) 314 74.6 1.4e-13
NP_996917 (OMIM: 131242,209880,613265,613712) endo ( 238) 314 74.6 1.5e-13
NP_001289385 (OMIM: 131242,209880,613265,613712) e ( 192) 309 73.5 2.5e-13
XP_005260370 (OMIM: 131242,209880,613265,613712) P ( 212) 309 73.6 2.7e-13
NP_996916 (OMIM: 131242,209880,613265,613712) endo ( 224) 309 73.6 2.9e-13
XP_011526957 (OMIM: 131242,209880,613265,613712) P ( 244) 309 73.6 3.1e-13
NP_001289198 (OMIM: 131241) endothelin-2 isoform 2 ( 145) 276 66.5 2.5e-11
NP_001947 (OMIM: 131241) endothelin-2 isoform 1 pr ( 178) 276 66.6 2.9e-11
XP_016856001 (OMIM: 131241) PREDICTED: endothelin- ( 132) 211 52.9 2.9e-07
>>NP_001946 (OMIM: 131240,612798,615706) endothelin-1 is (212 aa)
initn: 1497 init1: 1497 opt: 1497 Z-score: 1708.3 bits: 323.1 E(85289): 2.1e-88
Smith-Waterman score: 1497; 100.0% identity (100.0% similar) in 212 aa overlap (1-212:1-212)
10 20 30 40 50 60
pF1KB6 MDYLLMIFSLLFVACQGAPETAVLGAELSAVGENGGEKPTPSPPWRLRRSKRCSCSSLMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDYLLMIFSLLFVACQGAPETAVLGAELSAVGENGGEKPTPSPPWRLRRSKRCSCSSLMD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 KECVYFCHLDIIWVNTPEHVVPYGLGSPRSKRALENLLPTKATDRENRCQCASQKDKKCW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KECVYFCHLDIIWVNTPEHVVPYGLGSPRSKRALENLLPTKATDRENRCQCASQKDKKCW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 NFCQAGKELRAEDIMEKDWNNHKKGKDCSKLGKKCIYQQLVRGRKIRRSSEEHLRQTRSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFCQAGKELRAEDIMEKDWNNHKKGKDCSKLGKKCIYQQLVRGRKIRRSSEEHLRQTRSE
130 140 150 160 170 180
190 200 210
pF1KB6 TMRNSVKSSFHDPKLKGKPSRERYVTHNRAHW
::::::::::::::::::::::::::::::::
NP_001 TMRNSVKSSFHDPKLKGKPSRERYVTHNRAHW
190 200 210
>>XP_016865820 (OMIM: 131240,612798,615706) PREDICTED: e (212 aa)
initn: 1497 init1: 1497 opt: 1497 Z-score: 1708.3 bits: 323.1 E(85289): 2.1e-88
Smith-Waterman score: 1497; 100.0% identity (100.0% similar) in 212 aa overlap (1-212:1-212)
10 20 30 40 50 60
pF1KB6 MDYLLMIFSLLFVACQGAPETAVLGAELSAVGENGGEKPTPSPPWRLRRSKRCSCSSLMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDYLLMIFSLLFVACQGAPETAVLGAELSAVGENGGEKPTPSPPWRLRRSKRCSCSSLMD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 KECVYFCHLDIIWVNTPEHVVPYGLGSPRSKRALENLLPTKATDRENRCQCASQKDKKCW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KECVYFCHLDIIWVNTPEHVVPYGLGSPRSKRALENLLPTKATDRENRCQCASQKDKKCW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 NFCQAGKELRAEDIMEKDWNNHKKGKDCSKLGKKCIYQQLVRGRKIRRSSEEHLRQTRSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFCQAGKELRAEDIMEKDWNNHKKGKDCSKLGKKCIYQQLVRGRKIRRSSEEHLRQTRSE
130 140 150 160 170 180
190 200 210
pF1KB6 TMRNSVKSSFHDPKLKGKPSRERYVTHNRAHW
::::::::::::::::::::::::::::::::
XP_016 TMRNSVKSSFHDPKLKGKPSRERYVTHNRAHW
190 200 210
>>XP_011512632 (OMIM: 131240,612798,615706) PREDICTED: e (212 aa)
initn: 1497 init1: 1497 opt: 1497 Z-score: 1708.3 bits: 323.1 E(85289): 2.1e-88
Smith-Waterman score: 1497; 100.0% identity (100.0% similar) in 212 aa overlap (1-212:1-212)
10 20 30 40 50 60
pF1KB6 MDYLLMIFSLLFVACQGAPETAVLGAELSAVGENGGEKPTPSPPWRLRRSKRCSCSSLMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDYLLMIFSLLFVACQGAPETAVLGAELSAVGENGGEKPTPSPPWRLRRSKRCSCSSLMD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 KECVYFCHLDIIWVNTPEHVVPYGLGSPRSKRALENLLPTKATDRENRCQCASQKDKKCW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KECVYFCHLDIIWVNTPEHVVPYGLGSPRSKRALENLLPTKATDRENRCQCASQKDKKCW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 NFCQAGKELRAEDIMEKDWNNHKKGKDCSKLGKKCIYQQLVRGRKIRRSSEEHLRQTRSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NFCQAGKELRAEDIMEKDWNNHKKGKDCSKLGKKCIYQQLVRGRKIRRSSEEHLRQTRSE
130 140 150 160 170 180
190 200 210
pF1KB6 TMRNSVKSSFHDPKLKGKPSRERYVTHNRAHW
::::::::::::::::::::::::::::::::
XP_011 TMRNSVKSSFHDPKLKGKPSRERYVTHNRAHW
190 200 210
>>XP_011512633 (OMIM: 131240,612798,615706) PREDICTED: e (212 aa)
initn: 1497 init1: 1497 opt: 1497 Z-score: 1708.3 bits: 323.1 E(85289): 2.1e-88
Smith-Waterman score: 1497; 100.0% identity (100.0% similar) in 212 aa overlap (1-212:1-212)
10 20 30 40 50 60
pF1KB6 MDYLLMIFSLLFVACQGAPETAVLGAELSAVGENGGEKPTPSPPWRLRRSKRCSCSSLMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDYLLMIFSLLFVACQGAPETAVLGAELSAVGENGGEKPTPSPPWRLRRSKRCSCSSLMD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 KECVYFCHLDIIWVNTPEHVVPYGLGSPRSKRALENLLPTKATDRENRCQCASQKDKKCW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KECVYFCHLDIIWVNTPEHVVPYGLGSPRSKRALENLLPTKATDRENRCQCASQKDKKCW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 NFCQAGKELRAEDIMEKDWNNHKKGKDCSKLGKKCIYQQLVRGRKIRRSSEEHLRQTRSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NFCQAGKELRAEDIMEKDWNNHKKGKDCSKLGKKCIYQQLVRGRKIRRSSEEHLRQTRSE
130 140 150 160 170 180
190 200 210
pF1KB6 TMRNSVKSSFHDPKLKGKPSRERYVTHNRAHW
::::::::::::::::::::::::::::::::
XP_011 TMRNSVKSSFHDPKLKGKPSRERYVTHNRAHW
190 200 210
>>NP_001161791 (OMIM: 131240,612798,615706) endothelin-1 (211 aa)
initn: 1352 init1: 1352 opt: 1480 Z-score: 1689.0 bits: 319.6 E(85289): 2.4e-87
Smith-Waterman score: 1480; 99.5% identity (99.5% similar) in 212 aa overlap (1-212:1-211)
10 20 30 40 50 60
pF1KB6 MDYLLMIFSLLFVACQGAPETAVLGAELSAVGENGGEKPTPSPPWRLRRSKRCSCSSLMD
::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::
NP_001 MDYLLMIFSLLFVACQGAPET-VLGAELSAVGENGGEKPTPSPPWRLRRSKRCSCSSLMD
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 KECVYFCHLDIIWVNTPEHVVPYGLGSPRSKRALENLLPTKATDRENRCQCASQKDKKCW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KECVYFCHLDIIWVNTPEHVVPYGLGSPRSKRALENLLPTKATDRENRCQCASQKDKKCW
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 NFCQAGKELRAEDIMEKDWNNHKKGKDCSKLGKKCIYQQLVRGRKIRRSSEEHLRQTRSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NFCQAGKELRAEDIMEKDWNNHKKGKDCSKLGKKCIYQQLVRGRKIRRSSEEHLRQTRSE
120 130 140 150 160 170
190 200 210
pF1KB6 TMRNSVKSSFHDPKLKGKPSRERYVTHNRAHW
::::::::::::::::::::::::::::::::
NP_001 TMRNSVKSSFHDPKLKGKPSRERYVTHNRAHW
180 190 200 210
>>XP_011512634 (OMIM: 131240,612798,615706) PREDICTED: e (211 aa)
initn: 1352 init1: 1352 opt: 1480 Z-score: 1689.0 bits: 319.6 E(85289): 2.4e-87
Smith-Waterman score: 1480; 99.5% identity (99.5% similar) in 212 aa overlap (1-212:1-211)
10 20 30 40 50 60
pF1KB6 MDYLLMIFSLLFVACQGAPETAVLGAELSAVGENGGEKPTPSPPWRLRRSKRCSCSSLMD
::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::
XP_011 MDYLLMIFSLLFVACQGAPET-VLGAELSAVGENGGEKPTPSPPWRLRRSKRCSCSSLMD
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 KECVYFCHLDIIWVNTPEHVVPYGLGSPRSKRALENLLPTKATDRENRCQCASQKDKKCW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KECVYFCHLDIIWVNTPEHVVPYGLGSPRSKRALENLLPTKATDRENRCQCASQKDKKCW
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 NFCQAGKELRAEDIMEKDWNNHKKGKDCSKLGKKCIYQQLVRGRKIRRSSEEHLRQTRSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NFCQAGKELRAEDIMEKDWNNHKKGKDCSKLGKKCIYQQLVRGRKIRRSSEEHLRQTRSE
120 130 140 150 160 170
190 200 210
pF1KB6 TMRNSVKSSFHDPKLKGKPSRERYVTHNRAHW
::::::::::::::::::::::::::::::::
XP_011 TMRNSVKSSFHDPKLKGKPSRERYVTHNRAHW
180 190 200 210
>>XP_005260369 (OMIM: 131242,209880,613265,613712) PREDI (251 aa)
initn: 344 init1: 231 opt: 317 Z-score: 367.6 bits: 75.3 E(85289): 9.8e-14
Smith-Waterman score: 317; 33.7% identity (61.5% similar) in 169 aa overlap (13-173:58-224)
10 20 30 40
pF1KB6 MDYLLMIFSLLFVACQGAPETAVLGAELSAVGENGGEKPTPS
:: : .: . . . : : :. . .
XP_005 AGRRGVSQAPTAARSEGDCEETVAGPGEETVAGPGEGTVAPTALQGPSPGSPGQEQAAEG
30 40 50 60 70 80
50 60 70 80 90
pF1KB6 PPWRLRRSKRCSCSSLMDKECVYFCHLDIIWVNTPEHVVPYGL----GSPRSKRALENLL
: . .::.::.: . ::::::.:::::::.::::..::::: :: :.::. . :
XP_005 AP-EHHRSRRCTCFTYKDKECVYYCHLDIIWINTPEQTVPYGLSNYRGSFRGKRS-AGPL
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB6 P--TKATDREN-RCQCASQKDKKCWNFCQAGKELRAEDIMEKDWNNHKKGKDCSKLGKKC
: . . : . :: :... :: : .:: .. ... . .....:: . :
XP_005 PGNLQLSHRPHLRCACVGRYDKACLHFCTQTLDVSSNSRTAEKTDKEEEGKVRGANRGLC
150 160 170 180 190 200
160 170 180 190 200 210
pF1KB6 IYQQL-VRGRKIRRSSEEHLRQTRSETMRNSVKSSFHDPKLKGKPSRERYVTHNRAHW
.:. :. .. ... . :
XP_005 QRRQVEVKDQQSKQALDLHHPKLMPGSGLALAPSTCPRCLFQEGAP
210 220 230 240 250
>>NP_001289384 (OMIM: 131242,209880,613265,613712) endot (198 aa)
initn: 320 init1: 231 opt: 314 Z-score: 365.7 bits: 74.6 E(85289): 1.3e-13
Smith-Waterman score: 314; 37.6% identity (63.8% similar) in 141 aa overlap (13-146:58-196)
10 20 30 40
pF1KB6 MDYLLMIFSLLFVACQGAPETAVLGAELSAVGENGGEKPTPS
:: : .: . . . : : :. . .
NP_001 AGRRGVSQAPTAARSEGDCEETVAGPGEETVAGPGEGTVAPTALQGPSPGSPGQEQAAEG
30 40 50 60 70 80
50 60 70 80 90
pF1KB6 PPWRLRRSKRCSCSSLMDKECVYFCHLDIIWVNTPEHVVPYGL----GSPRSKRALENLL
: . .::.::.: . ::::::.:::::::.::::..::::: :: :.::. . :
NP_001 AP-EHHRSRRCTCFTYKDKECVYYCHLDIIWINTPEQTVPYGLSNYRGSFRGKRS-AGPL
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB6 P--TKATDREN-RCQCASQKDKKCWNFCQAGKELRAEDIMEKDWNNHKKGKDCSKLGKKC
: . . : . :: :... :: : .:: .. ... . .....::
NP_001 PGNLQLSHRPHLRCACVGRYDKACLHFCTQTLDVSSNSRTAEKTDKEEEGKTG
150 160 170 180 190
160 170 180 190 200 210
pF1KB6 IYQQLVRGRKIRRSSEEHLRQTRSETMRNSVKSSFHDPKLKGKPSRERYVTHNRAHW
>>XP_006723797 (OMIM: 131242,209880,613265,613712) PREDI (208 aa)
initn: 320 init1: 231 opt: 314 Z-score: 365.4 bits: 74.6 E(85289): 1.3e-13
Smith-Waterman score: 314; 37.6% identity (63.8% similar) in 141 aa overlap (13-146:58-196)
10 20 30 40
pF1KB6 MDYLLMIFSLLFVACQGAPETAVLGAELSAVGENGGEKPTPS
:: : .: . . . : : :. . .
XP_006 AGRRGVSQAPTAARSEGDCEETVAGPGEETVAGPGEGTVAPTALQGPSPGSPGQEQAAEG
30 40 50 60 70 80
50 60 70 80 90
pF1KB6 PPWRLRRSKRCSCSSLMDKECVYFCHLDIIWVNTPEHVVPYGL----GSPRSKRALENLL
: . .::.::.: . ::::::.:::::::.::::..::::: :: :.::. . :
XP_006 AP-EHHRSRRCTCFTYKDKECVYYCHLDIIWINTPEQTVPYGLSNYRGSFRGKRS-AGPL
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB6 P--TKATDREN-RCQCASQKDKKCWNFCQAGKELRAEDIMEKDWNNHKKGKDCSKLGKKC
: . . : . :: :... :: : .:: .. ... . .....::
XP_006 PGNLQLSHRPHLRCACVGRYDKACLHFCTQTLDVSSNSRTAEKTDKEEEGKVRGANRGLC
150 160 170 180 190 200
160 170 180 190 200 210
pF1KB6 IYQQLVRGRKIRRSSEEHLRQTRSETMRNSVKSSFHDPKLKGKPSRERYVTHNRAHW
XP_006 QRR
>>NP_996915 (OMIM: 131242,209880,613265,613712) endothel (219 aa)
initn: 320 init1: 231 opt: 314 Z-score: 365.0 bits: 74.6 E(85289): 1.4e-13
Smith-Waterman score: 314; 37.6% identity (63.8% similar) in 141 aa overlap (13-146:58-196)
10 20 30 40
pF1KB6 MDYLLMIFSLLFVACQGAPETAVLGAELSAVGENGGEKPTPS
:: : .: . . . : : :. . .
NP_996 AGRRGVSQAPTAARSEGDCEETVAGPGEETVAGPGEGTVAPTALQGPSPGSPGQEQAAEG
30 40 50 60 70 80
50 60 70 80 90
pF1KB6 PPWRLRRSKRCSCSSLMDKECVYFCHLDIIWVNTPEHVVPYGL----GSPRSKRALENLL
: . .::.::.: . ::::::.:::::::.::::..::::: :: :.::. . :
NP_996 AP-EHHRSRRCTCFTYKDKECVYYCHLDIIWINTPEQTVPYGLSNYRGSFRGKRS-AGPL
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB6 P--TKATDREN-RCQCASQKDKKCWNFCQAGKELRAEDIMEKDWNNHKKGKDCSKLGKKC
: . . : . :: :... :: : .:: .. ... . .....::
NP_996 PGNLQLSHRPHLRCACVGRYDKACLHFCTQTLDVSSNSRTAEKTDKEEEGKVRGANRGLC
150 160 170 180 190 200
160 170 180 190 200 210
pF1KB6 IYQQLVRGRKIRRSSEEHLRQTRSETMRNSVKSSFHDPKLKGKPSRERYVTHNRAHW
NP_996 QRRLKSRTNKASRL
210
212 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 11:23:35 2016 done: Fri Nov 4 11:23:36 2016
Total Scan time: 5.660 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]