FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6955, 212 aa 1>>>pF1KB6955 212 - 212 aa - 212 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9288+/-0.000346; mu= 16.1981+/- 0.021 mean_var=78.7886+/-15.864, 0's: 0 Z-trim(116.4): 112 B-trim: 739 in 2/52 Lambda= 0.144492 statistics sampled from 27389 (27540) to 27389 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.712), E-opt: 0.2 (0.323), width: 16 Scan time: 4.670 The best scores are: opt bits E(85289) NP_005183 (OMIM: 123832) cyclin-dependent kinase i ( 212) 1448 310.9 9.9e-85 NP_001317102 (OMIM: 123832) cyclin-dependent kinas ( 203) 1267 273.1 2.2e-73 NP_001124323 (OMIM: 123832) cyclin-dependent kinas ( 172) 1103 238.9 3.8e-63 >>NP_005183 (OMIM: 123832) cyclin-dependent kinase inhib (212 aa) initn: 1448 init1: 1448 opt: 1448 Z-score: 1642.1 bits: 310.9 E(85289): 9.9e-85 Smith-Waterman score: 1448; 100.0% identity (100.0% similar) in 212 aa overlap (1-212:1-212) 10 20 30 40 50 60 pF1KB6 MKPPSSIQTSEFDSSDEEPIEDEQTPIHISWLSLSRVNCSQFLGLCALPGCKFKDVRRNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MKPPSSIQTSEFDSSDEEPIEDEQTPIHISWLSLSRVNCSQFLGLCALPGCKFKDVRRNV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 QKDTEELKSCGIQDIFVFCTRGELSKYRVPNLLDLYQQCGIITHHHPIADGGTPDIASCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 QKDTEELKSCGIQDIFVFCTRGELSKYRVPNLLDLYQQCGIITHHHPIADGGTPDIASCC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 EIMEELTTCLKNYRKTLIHCYGGLGRSCLVAACLLLYLSDTISPEQAIDSLRDLRGSGAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 EIMEELTTCLKNYRKTLIHCYGGLGRSCLVAACLLLYLSDTISPEQAIDSLRDLRGSGAI 130 140 150 160 170 180 190 200 210 pF1KB6 QTIKQYNYLHEFRDKLAAHLSSRDSQSRSVSR :::::::::::::::::::::::::::::::: NP_005 QTIKQYNYLHEFRDKLAAHLSSRDSQSRSVSR 190 200 210 >>NP_001317102 (OMIM: 123832) cyclin-dependent kinase in (203 aa) initn: 1267 init1: 1267 opt: 1267 Z-score: 1438.5 bits: 273.1 E(85289): 2.2e-73 Smith-Waterman score: 1267; 100.0% identity (100.0% similar) in 184 aa overlap (1-184:1-184) 10 20 30 40 50 60 pF1KB6 MKPPSSIQTSEFDSSDEEPIEDEQTPIHISWLSLSRVNCSQFLGLCALPGCKFKDVRRNV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKPPSSIQTSEFDSSDEEPIEDEQTPIHISWLSLSRVNCSQFLGLCALPGCKFKDVRRNV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 QKDTEELKSCGIQDIFVFCTRGELSKYRVPNLLDLYQQCGIITHHHPIADGGTPDIASCC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QKDTEELKSCGIQDIFVFCTRGELSKYRVPNLLDLYQQCGIITHHHPIADGGTPDIASCC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 EIMEELTTCLKNYRKTLIHCYGGLGRSCLVAACLLLYLSDTISPEQAIDSLRDLRGSGAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EIMEELTTCLKNYRKTLIHCYGGLGRSCLVAACLLLYLSDTISPEQAIDSLRDLRGSGAI 130 140 150 160 170 180 190 200 210 pF1KB6 QTIKQYNYLHEFRDKLAAHLSSRDSQSRSVSR :::: NP_001 QTIKDLPTSQFLPQSVLGMDPLT 190 200 >>NP_001124323 (OMIM: 123832) cyclin-dependent kinase in (172 aa) initn: 1154 init1: 1103 opt: 1103 Z-score: 1254.6 bits: 238.9 E(85289): 3.8e-63 Smith-Waterman score: 1103; 100.0% identity (100.0% similar) in 162 aa overlap (51-212:11-172) 30 40 50 60 70 80 pF1KB6 EDEQTPIHISWLSLSRVNCSQFLGLCALPGCKFKDVRRNVQKDTEELKSCGIQDIFVFCT :::::::::::::::::::::::::::::: NP_001 MKPPSSIQTSCKFKDVRRNVQKDTEELKSCGIQDIFVFCT 10 20 30 40 90 100 110 120 130 140 pF1KB6 RGELSKYRVPNLLDLYQQCGIITHHHPIADGGTPDIASCCEIMEELTTCLKNYRKTLIHC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RGELSKYRVPNLLDLYQQCGIITHHHPIADGGTPDIASCCEIMEELTTCLKNYRKTLIHC 50 60 70 80 90 100 150 160 170 180 190 200 pF1KB6 YGGLGRSCLVAACLLLYLSDTISPEQAIDSLRDLRGSGAIQTIKQYNYLHEFRDKLAAHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YGGLGRSCLVAACLLLYLSDTISPEQAIDSLRDLRGSGAIQTIKQYNYLHEFRDKLAAHL 110 120 130 140 150 160 210 pF1KB6 SSRDSQSRSVSR :::::::::::: NP_001 SSRDSQSRSVSR 170 212 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 18:20:13 2016 done: Sat Nov 5 18:20:13 2016 Total Scan time: 4.670 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]