Result of FASTA (omim) for
pF1KB6965
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6965, 173 aa
1>>>pF1KB6965 173 - 173 aa - 173 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.4555+/-0.000432; mu= 17.1857+/- 0.026
mean_var=68.5914+/-14.540, 0's: 0 Z-trim(110.3): 48 B-trim: 0 in 0/53
Lambda= 0.154860
statistics sampled from 18559 (18599) to 18559 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.563), E-opt: 0.2 (0.218), width: 16
Scan time: 3.990
The best scores are: opt bits E(85289)
NP_001155220 (OMIM: 154045,615277) lens fiber memb ( 173) 1205 278.1 4.8e-75
NP_085915 (OMIM: 154045,615277) lens fiber membran ( 215) 782 183.7 1.6e-46
NP_001414 (OMIM: 602333) epithelial membrane prote ( 157) 199 53.3 2e-07
NP_005592 (OMIM: 606008) protein NKG7 [Homo sapien ( 165) 168 46.4 2.5e-05
XP_006720927 (OMIM: 602334,615861) PREDICTED: epit ( 167) 156 43.8 0.00016
NP_001415 (OMIM: 602334,615861) epithelial membran ( 167) 156 43.8 0.00016
NP_001268384 (OMIM: 118220,118300,139393,145900,16 ( 160) 146 41.5 0.00075
NP_696996 (OMIM: 118220,118300,139393,145900,16250 ( 160) 146 41.5 0.00075
NP_001268385 (OMIM: 118220,118300,139393,145900,16 ( 160) 146 41.5 0.00075
NP_000295 (OMIM: 118220,118300,139393,145900,16250 ( 160) 146 41.5 0.00075
NP_696997 (OMIM: 118220,118300,139393,145900,16250 ( 160) 146 41.5 0.00075
NP_001002026 (OMIM: 609210) claudin-18 isoform 2 [ ( 261) 136 39.5 0.005
>>NP_001155220 (OMIM: 154045,615277) lens fiber membrane (173 aa)
initn: 1205 init1: 1205 opt: 1205 Z-score: 1468.4 bits: 278.1 E(85289): 4.8e-75
Smith-Waterman score: 1205; 100.0% identity (100.0% similar) in 173 aa overlap (1-173:1-173)
10 20 30 40 50 60
pF1KB6 MYSFMGGGLFCAWVGTILLVVAMATDHWMQYRLSGSFAHQGLWRYCLGNKCYLQTDSIAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MYSFMGGGLFCAWVGTILLVVAMATDHWMQYRLSGSFAHQGLWRYCLGNKCYLQTDSIAY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 WNATRAFMILSALCAISGIIMGIMAFAHQPTFSRISRPFSAGIMFFSSTLFVVLALAIYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WNATRAFMILSALCAISGIIMGIMAFAHQPTFSRISRPFSAGIMFFSSTLFVVLALAIYT
70 80 90 100 110 120
130 140 150 160 170
pF1KB6 GVTVSFLGRRFGDWRFSWSYILGWVAVLMTFFAGIFYMCAYRVHECRRLSTPR
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVTVSFLGRRFGDWRFSWSYILGWVAVLMTFFAGIFYMCAYRVHECRRLSTPR
130 140 150 160 170
>>NP_085915 (OMIM: 154045,615277) lens fiber membrane in (215 aa)
initn: 1191 init1: 782 opt: 782 Z-score: 956.4 bits: 183.7 E(85289): 1.6e-46
Smith-Waterman score: 1039; 79.5% identity (79.5% similar) in 205 aa overlap (11-173:11-215)
10 20 30 40 50
pF1KB6 MYSFMGGGLFCAWVGTILLVVAMATDHWMQYRLSGSFAHQGLWRYCLGNKCYLQTDSI--
::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 MYSFMGGGLFCAWVGTILLVVAMATDHWMQYRLSGSFAHQGLWRYCLGNKCYLQTDSIGE
10 20 30 40 50 60
60 70
pF1KB6 ----------------------------------------AYWNATRAFMILSALCAISG
::::::::::::::::::::
NP_085 PPGQGPGRAWGKSRADLGAQGHLYSRWRTLRLKEGKGATQAYWNATRAFMILSALCAISG
70 80 90 100 110 120
80 90 100 110 120 130
pF1KB6 IIMGIMAFAHQPTFSRISRPFSAGIMFFSSTLFVVLALAIYTGVTVSFLGRRFGDWRFSW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 IIMGIMAFAHQPTFSRISRPFSAGIMFFSSTLFVVLALAIYTGVTVSFLGRRFGDWRFSW
130 140 150 160 170 180
140 150 160 170
pF1KB6 SYILGWVAVLMTFFAGIFYMCAYRVHECRRLSTPR
:::::::::::::::::::::::::::::::::::
NP_085 SYILGWVAVLMTFFAGIFYMCAYRVHECRRLSTPR
190 200 210
>>NP_001414 (OMIM: 602333) epithelial membrane protein 1 (157 aa)
initn: 141 init1: 79 opt: 199 Z-score: 254.2 bits: 53.3 E(85289): 2e-07
Smith-Waterman score: 199; 27.7% identity (62.9% similar) in 159 aa overlap (8-158:7-152)
10 20 30 40 50
pF1KB6 MYSFMGGGLFCAWVGT-ILLVVAMATDHWMQYRLSGSF-AHQGLWRYCLGNKCYLQTDSI
:.: . ..: :.: :. .. :. .:.. : :::. : . .: .::.
NP_001 MLVLLAGIFVVHIATVIMLFVSTIANVWL---VSNTVDASVGLWKNCTNISC---SDSL
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 AYWN-----ATRAFMILSAL-CAISGIIMGIMAFAHQPTFSRISRPFSAGIMFFSSTLFV
.: . ...:::::: . :.:. ... .. : :. . .: : .: . : .
NP_001 SYASEDALKTVQAFMILSIIFCVIALLVFVFQLF----TMEKGNRFFLSGATTLVCWLCI
60 70 80 90 100
120 130 140 150 160 170
pF1KB6 VLALAIYTGVTVSFLGRRFGDWRFSWSYILGWVAVLMTFFAGIFYMCAYRVHECRRLSTP
.....:::. . .: ... ..::::::. ..:. :..:.
NP_001 LVGVSIYTS---HYANRDGTQYHHGYSYILGWICFCFSFIIGVLYLVLRKK
110 120 130 140 150
pF1KB6 R
>>NP_005592 (OMIM: 606008) protein NKG7 [Homo sapiens] (165 aa)
initn: 188 init1: 86 opt: 168 Z-score: 216.5 bits: 46.4 E(85289): 2.5e-05
Smith-Waterman score: 173; 25.5% identity (59.6% similar) in 161 aa overlap (3-161:8-154)
10 20 30 40 50
pF1KB6 MYSFMGGGLFCAWVGTILLVVAMATDHWMQYRLSGSFAHQGLWRYCLGNKCYLQT
...::.: : .. ..:..:: :.. ::.::: :
NP_005 MELCRSLALLGGSL-----GLMFCLIALSTDFWFEAVGPTHSAHSGLWPTGHG-------
10 20 30 40
60 70 80 90 100 110
pF1KB6 DSIA-YWNATRAFMILSALCAISGIIMGIMAFAHQPT-FSRISRPFSAGIMFFSSTLFVV
: :. : ..:..: :...: :. . ....... :. : :. . :.... .:
NP_005 DIISGYIHVTQTFSIMAVLWAL--VSVSFLVLSCFPSLFPPGHGPLVSTTAAFAAAISMV
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB6 LALAIYTGVTVSFLGRRFGDWRFSWSYILGWVAVLMTFFAGIFYMCAYRVHECRRLSTPR
.:.:.::. . . . ::::. ::::.... . .: . . :.
NP_005 VAMAVYTSERWDQPPHPQIQTFFSWSFYLGWVSAILLLCTGALSLGAHCGGPRPGYETL
110 120 130 140 150 160
>>XP_006720927 (OMIM: 602334,615861) PREDICTED: epitheli (167 aa)
initn: 118 init1: 78 opt: 156 Z-score: 202.0 bits: 43.8 E(85289): 0.00016
Smith-Waterman score: 156; 28.9% identity (57.9% similar) in 152 aa overlap (18-158:18-161)
10 20 30 40 50
pF1KB6 MYSFMGGGLFCAWVGTILLVVAMATDHWMQYRLSGSFAHQGLWRYCLGN-KCYLQTDSIA
:: .: . . : :. .:: : .: .: . .::.
XP_006 MLVLLAFIIAFHITSAALLFIATVDNAWW----VGDEFFADVWRICTNNTNCTVINDSFQ
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 YWN---ATRAFMILSA-LCAISGIIMGIMAFAHQPTFSRISRPFSAGIMFFSSTLFVVLA
.. :..: ::::. :: :. .:. .. : ... : ..:. . : : :..:
XP_006 EYSTLQAVQATMILSTILCCIAFFIFVLQLF----RLKQGERFVLTSIIQLMSCLCVMIA
60 70 80 90 100 110
120 130 140 150 160
pF1KB6 LAIYTGVTVSFLGR--RFG----DWRFSWSYILGWVAVLMTFFAGIFYMCAYRVHECRRL
.::: .. . .: . ...::::.::: ::..:..:.
XP_006 ASIYTDRREDIHDKNAKFYPVTREGSYGYSYILAWVAFACTFISGMMYLILRKRK
120 130 140 150 160
170
pF1KB6 STPR
>>NP_001415 (OMIM: 602334,615861) epithelial membrane pr (167 aa)
initn: 118 init1: 78 opt: 156 Z-score: 202.0 bits: 43.8 E(85289): 0.00016
Smith-Waterman score: 156; 28.9% identity (57.9% similar) in 152 aa overlap (18-158:18-161)
10 20 30 40 50
pF1KB6 MYSFMGGGLFCAWVGTILLVVAMATDHWMQYRLSGSFAHQGLWRYCLGN-KCYLQTDSIA
:: .: . . : :. .:: : .: .: . .::.
NP_001 MLVLLAFIIAFHITSAALLFIATVDNAWW----VGDEFFADVWRICTNNTNCTVINDSFQ
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 YWN---ATRAFMILSA-LCAISGIIMGIMAFAHQPTFSRISRPFSAGIMFFSSTLFVVLA
.. :..: ::::. :: :. .:. .. : ... : ..:. . : : :..:
NP_001 EYSTLQAVQATMILSTILCCIAFFIFVLQLF----RLKQGERFVLTSIIQLMSCLCVMIA
60 70 80 90 100 110
120 130 140 150 160
pF1KB6 LAIYTGVTVSFLGR--RFG----DWRFSWSYILGWVAVLMTFFAGIFYMCAYRVHECRRL
.::: .. . .: . ...::::.::: ::..:..:.
NP_001 ASIYTDRREDIHDKNAKFYPVTREGSYGYSYILAWVAFACTFISGMMYLILRKRK
120 130 140 150 160
170
pF1KB6 STPR
>>NP_001268384 (OMIM: 118220,118300,139393,145900,162500 (160 aa)
initn: 107 init1: 58 opt: 146 Z-score: 190.1 bits: 41.5 E(85289): 0.00075
Smith-Waterman score: 146; 26.5% identity (59.9% similar) in 147 aa overlap (17-158:17-154)
10 20 30 40 50
pF1KB6 MYSFMGGGLFCAWVGTILLVVAMATDHWMQYRLSGSFAHQGLWRYCL----GNKCYLQTD
.:: :. ...:. :. ::. : :: . ..
NP_001 MLLLLLSIIVLHVAVLVLLFVSTIVSQWI----VGNGHATDLWQNCSTSSSGNVHHCFSS
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 SIAYW-NATRAFMILSALCAISGIIMGIMAFAHQPTFSRISRPFSAGIMFFSSTLFVVLA
: : ....: :::: . .: .. .. : . :... .: . .::. . . : :. :
NP_001 SPNEWLQSVQATMILSIIFSILSL---FLFFCQLFTLTKGGRFYITGIFQILAGLCVMSA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 LAIYTGVTVSFLGRRFGDWRFSWSYILGWVAVLMTFFAGIFYMCAYRVHECRRLSTPR
:::: . . .:. ....:::.::: .....:..:.
NP_001 AAIYTVRHPEW--HLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE
120 130 140 150 160
>>NP_696996 (OMIM: 118220,118300,139393,145900,162500,18 (160 aa)
initn: 107 init1: 58 opt: 146 Z-score: 190.1 bits: 41.5 E(85289): 0.00075
Smith-Waterman score: 146; 26.5% identity (59.9% similar) in 147 aa overlap (17-158:17-154)
10 20 30 40 50
pF1KB6 MYSFMGGGLFCAWVGTILLVVAMATDHWMQYRLSGSFAHQGLWRYCL----GNKCYLQTD
.:: :. ...:. :. ::. : :: . ..
NP_696 MLLLLLSIIVLHVAVLVLLFVSTIVSQWI----VGNGHATDLWQNCSTSSSGNVHHCFSS
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 SIAYW-NATRAFMILSALCAISGIIMGIMAFAHQPTFSRISRPFSAGIMFFSSTLFVVLA
: : ....: :::: . .: .. .. : . :... .: . .::. . . : :. :
NP_696 SPNEWLQSVQATMILSIIFSILSL---FLFFCQLFTLTKGGRFYITGIFQILAGLCVMSA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 LAIYTGVTVSFLGRRFGDWRFSWSYILGWVAVLMTFFAGIFYMCAYRVHECRRLSTPR
:::: . . .:. ....:::.::: .....:..:.
NP_696 AAIYTVRHPEW--HLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE
120 130 140 150 160
>>NP_001268385 (OMIM: 118220,118300,139393,145900,162500 (160 aa)
initn: 107 init1: 58 opt: 146 Z-score: 190.1 bits: 41.5 E(85289): 0.00075
Smith-Waterman score: 146; 26.5% identity (59.9% similar) in 147 aa overlap (17-158:17-154)
10 20 30 40 50
pF1KB6 MYSFMGGGLFCAWVGTILLVVAMATDHWMQYRLSGSFAHQGLWRYCL----GNKCYLQTD
.:: :. ...:. :. ::. : :: . ..
NP_001 MLLLLLSIIVLHVAVLVLLFVSTIVSQWI----VGNGHATDLWQNCSTSSSGNVHHCFSS
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 SIAYW-NATRAFMILSALCAISGIIMGIMAFAHQPTFSRISRPFSAGIMFFSSTLFVVLA
: : ....: :::: . .: .. .. : . :... .: . .::. . . : :. :
NP_001 SPNEWLQSVQATMILSIIFSILSL---FLFFCQLFTLTKGGRFYITGIFQILAGLCVMSA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 LAIYTGVTVSFLGRRFGDWRFSWSYILGWVAVLMTFFAGIFYMCAYRVHECRRLSTPR
:::: . . .:. ....:::.::: .....:..:.
NP_001 AAIYTVRHPEW--HLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE
120 130 140 150 160
>>NP_000295 (OMIM: 118220,118300,139393,145900,162500,18 (160 aa)
initn: 107 init1: 58 opt: 146 Z-score: 190.1 bits: 41.5 E(85289): 0.00075
Smith-Waterman score: 146; 26.5% identity (59.9% similar) in 147 aa overlap (17-158:17-154)
10 20 30 40 50
pF1KB6 MYSFMGGGLFCAWVGTILLVVAMATDHWMQYRLSGSFAHQGLWRYCL----GNKCYLQTD
.:: :. ...:. :. ::. : :: . ..
NP_000 MLLLLLSIIVLHVAVLVLLFVSTIVSQWI----VGNGHATDLWQNCSTSSSGNVHHCFSS
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 SIAYW-NATRAFMILSALCAISGIIMGIMAFAHQPTFSRISRPFSAGIMFFSSTLFVVLA
: : ....: :::: . .: .. .. : . :... .: . .::. . . : :. :
NP_000 SPNEWLQSVQATMILSIIFSILSL---FLFFCQLFTLTKGGRFYITGIFQILAGLCVMSA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 LAIYTGVTVSFLGRRFGDWRFSWSYILGWVAVLMTFFAGIFYMCAYRVHECRRLSTPR
:::: . . .:. ....:::.::: .....:..:.
NP_000 AAIYTVRHPEW--HLNSDYSYGFAYILAWVAFPLALLSGVIYVILRKRE
120 130 140 150 160
173 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 11:12:45 2016 done: Fri Nov 4 11:12:45 2016
Total Scan time: 3.990 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]