FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6967, 215 aa 1>>>pF1KB6967 215 - 215 aa - 215 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.6745+/-0.000265; mu= 9.0610+/- 0.017 mean_var=122.0315+/-25.095, 0's: 0 Z-trim(122.2): 14 B-trim: 389 in 1/53 Lambda= 0.116102 statistics sampled from 39884 (39919) to 39884 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.803), E-opt: 0.2 (0.468), width: 16 Scan time: 6.180 The best scores are: opt bits E(85289) NP_653260 (OMIM: 608365) T-complex protein 10A hom ( 215) 1451 252.9 2.8e-67 XP_016866719 (OMIM: 187020) PREDICTED: T-complex p ( 211) 916 163.3 2.6e-40 XP_016866718 (OMIM: 187020) PREDICTED: T-complex p ( 269) 916 163.4 3.2e-40 XP_016866717 (OMIM: 187020) PREDICTED: T-complex p ( 285) 916 163.4 3.3e-40 NP_004601 (OMIM: 187020) T-complex protein 10A hom ( 326) 916 163.5 3.7e-40 XP_011534387 (OMIM: 187020) PREDICTED: T-complex p ( 329) 916 163.5 3.7e-40 XP_011534386 (OMIM: 187020) PREDICTED: T-complex p ( 329) 916 163.5 3.7e-40 XP_016866720 (OMIM: 187020) PREDICTED: T-complex p ( 390) 916 163.5 4.3e-40 XP_011534390 (OMIM: 187020) PREDICTED: T-complex p ( 278) 665 121.4 1.5e-27 XP_011534384 (OMIM: 187020) PREDICTED: T-complex p ( 335) 471 88.9 1e-17 XP_011534392 (OMIM: 187020) PREDICTED: T-complex p ( 257) 462 87.3 2.4e-17 NP_060921 (OMIM: 608393,609279,613676) centromere (1338) 202 44.3 0.0011 >>NP_653260 (OMIM: 608365) T-complex protein 10A homolog (215 aa) initn: 1451 init1: 1451 opt: 1451 Z-score: 1328.8 bits: 252.9 E(85289): 2.8e-67 Smith-Waterman score: 1451; 100.0% identity (100.0% similar) in 215 aa overlap (1-215:1-215) 10 20 30 40 50 60 pF1KB6 MLAGQLEARDPKEGTHPEDPCPGAGAVMEKTAVAAEVLTEDCNTGEMPPLQQQIIRLHQE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 MLAGQLEARDPKEGTHPEDPCPGAGAVMEKTAVAAEVLTEDCNTGEMPPLQQQIIRLHQE 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LGRQKSLWADVHGKLRSHIDALREQNMELREKLRALQLQRWKARKKSAASPHAGQESHTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 LGRQKSLWADVHGKLRSHIDALREQNMELREKLRALQLQRWKARKKSAASPHAGQESHTL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ALEPAFGKISPLSADEETIPKYAGHKNQSATLLGQRSSSNNSAPPKPMSLKIERISSWKT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_653 ALEPAFGKISPLSADEETIPKYAGHKNQSATLLGQRSSSNNSAPPKPMSLKIERISSWKT 130 140 150 160 170 180 190 200 210 pF1KB6 PPQENRDKNLSRRRQDRRATPTGRPTPCAERRGGV ::::::::::::::::::::::::::::::::::: NP_653 PPQENRDKNLSRRRQDRRATPTGRPTPCAERRGGV 190 200 210 >>XP_016866719 (OMIM: 187020) PREDICTED: T-complex prote (211 aa) initn: 916 init1: 916 opt: 916 Z-score: 844.6 bits: 163.3 E(85289): 2.6e-40 Smith-Waterman score: 916; 75.8% identity (87.1% similar) in 186 aa overlap (28-213:1-186) 10 20 30 40 50 60 pF1KB6 MLAGQLEARDPKEGTHPEDPCPGAGAVMEKTAVAAEVLTEDCNTGEMPPLQQQIIRLHQE :::: .:::: :: :.:::: ::::: :::: XP_016 MEKTPAAAEVPREDSNAGEMPSLQQQITSLHQE 10 20 30 70 80 90 100 110 120 pF1KB6 LGRQKSLWADVHGKLRSHIDALREQNMELREKLRALQLQRWKARKKSAASPHAGQESHTL ::::.:::::.: ::.::.::::.:: ::::.::.:: :.:.: :: :::::::.::::: XP_016 LGRQQSLWADIHRKLQSHMDALRKQNRELREELRGLQRQQWEAGKKPAASPHAGRESHTL 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB6 ALEPAFGKISPLSADEETIPKYAGHKNQSATLLGQRSSSNNSAPPKPMSLKIERISSWKT :::::::::: :::::.: :::::.:.::::::::: :::. ::::::::: :::.: :: XP_016 ALEPAFGKISHLSADEDTTPKYAGRKSQSATLLGQRWSSNHLAPPKPMSLKTERINSGKT 100 110 120 130 140 150 190 200 210 pF1KB6 PPQENRDKNLSRRRQDRRATPTGRPTPCAERRGGV ::::.:.:. ::::: .::::::: ::::: XP_016 PPQEDREKSPPGRRQDRSPAPTGRPTPGAERRGVSEDGKVTSETWVTLHWQHGKFRFR 160 170 180 190 200 210 >>XP_016866718 (OMIM: 187020) PREDICTED: T-complex prote (269 aa) initn: 916 init1: 916 opt: 916 Z-score: 843.1 bits: 163.4 E(85289): 3.2e-40 Smith-Waterman score: 916; 75.8% identity (87.1% similar) in 186 aa overlap (28-213:1-186) 10 20 30 40 50 60 pF1KB6 MLAGQLEARDPKEGTHPEDPCPGAGAVMEKTAVAAEVLTEDCNTGEMPPLQQQIIRLHQE :::: .:::: :: :.:::: ::::: :::: XP_016 MEKTPAAAEVPREDSNAGEMPSLQQQITSLHQE 10 20 30 70 80 90 100 110 120 pF1KB6 LGRQKSLWADVHGKLRSHIDALREQNMELREKLRALQLQRWKARKKSAASPHAGQESHTL ::::.:::::.: ::.::.::::.:: ::::.::.:: :.:.: :: :::::::.::::: XP_016 LGRQQSLWADIHRKLQSHMDALRKQNRELREELRGLQRQQWEAGKKPAASPHAGRESHTL 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB6 ALEPAFGKISPLSADEETIPKYAGHKNQSATLLGQRSSSNNSAPPKPMSLKIERISSWKT :::::::::: :::::.: :::::.:.::::::::: :::. ::::::::: :::.: :: XP_016 ALEPAFGKISHLSADEDTTPKYAGRKSQSATLLGQRWSSNHLAPPKPMSLKTERINSGKT 100 110 120 130 140 150 190 200 210 pF1KB6 PPQENRDKNLSRRRQDRRATPTGRPTPCAERRGGV ::::.:.:. ::::: .::::::: ::::: XP_016 PPQEDREKSPPGRRQDRSPAPTGRPTPGAERRGVSEDGKIMHPSSRSPQNSGGRKSPVQA 160 170 180 190 200 210 XP_016 SQATTLQEQTAAARGAGEQDRSSSVLGSSEGGFLSRVQADEFASSAPDSAERQAGP 220 230 240 250 260 >>XP_016866717 (OMIM: 187020) PREDICTED: T-complex prote (285 aa) initn: 916 init1: 916 opt: 916 Z-score: 842.8 bits: 163.4 E(85289): 3.3e-40 Smith-Waterman score: 916; 75.8% identity (87.1% similar) in 186 aa overlap (28-213:1-186) 10 20 30 40 50 60 pF1KB6 MLAGQLEARDPKEGTHPEDPCPGAGAVMEKTAVAAEVLTEDCNTGEMPPLQQQIIRLHQE :::: .:::: :: :.:::: ::::: :::: XP_016 MEKTPAAAEVPREDSNAGEMPSLQQQITSLHQE 10 20 30 70 80 90 100 110 120 pF1KB6 LGRQKSLWADVHGKLRSHIDALREQNMELREKLRALQLQRWKARKKSAASPHAGQESHTL ::::.:::::.: ::.::.::::.:: ::::.::.:: :.:.: :: :::::::.::::: XP_016 LGRQQSLWADIHRKLQSHMDALRKQNRELREELRGLQRQQWEAGKKPAASPHAGRESHTL 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB6 ALEPAFGKISPLSADEETIPKYAGHKNQSATLLGQRSSSNNSAPPKPMSLKIERISSWKT :::::::::: :::::.: :::::.:.::::::::: :::. ::::::::: :::.: :: XP_016 ALEPAFGKISHLSADEDTTPKYAGRKSQSATLLGQRWSSNHLAPPKPMSLKTERINSGKT 100 110 120 130 140 150 190 200 210 pF1KB6 PPQENRDKNLSRRRQDRRATPTGRPTPCAERRGGV ::::.:.:. ::::: .::::::: ::::: XP_016 PPQEDREKSPPGRRQDRSPAPTGRPTPGAERRGVSEDGKIMHPSSRSPQNSGGRKSPVQA 160 170 180 190 200 210 XP_016 SQATTLQEQTAAARGAGEQDRSSSVLGSSEGGFLSRVQADEFASSAPDSAERQFSVDINR 220 230 240 250 260 270 >>NP_004601 (OMIM: 187020) T-complex protein 10A homolog (326 aa) initn: 916 init1: 916 opt: 916 Z-score: 842.0 bits: 163.5 E(85289): 3.7e-40 Smith-Waterman score: 916; 75.8% identity (87.1% similar) in 186 aa overlap (28-213:1-186) 10 20 30 40 50 60 pF1KB6 MLAGQLEARDPKEGTHPEDPCPGAGAVMEKTAVAAEVLTEDCNTGEMPPLQQQIIRLHQE :::: .:::: :: :.:::: ::::: :::: NP_004 MEKTPAAAEVPREDSNAGEMPSLQQQITSLHQE 10 20 30 70 80 90 100 110 120 pF1KB6 LGRQKSLWADVHGKLRSHIDALREQNMELREKLRALQLQRWKARKKSAASPHAGQESHTL ::::.:::::.: ::.::.::::.:: ::::.::.:: :.:.: :: :::::::.::::: NP_004 LGRQQSLWADIHRKLQSHMDALRKQNRELREELRGLQRQQWEAGKKPAASPHAGRESHTL 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB6 ALEPAFGKISPLSADEETIPKYAGHKNQSATLLGQRSSSNNSAPPKPMSLKIERISSWKT :::::::::: :::::.: :::::.:.::::::::: :::. ::::::::: :::.: :: NP_004 ALEPAFGKISHLSADEDTTPKYAGRKSQSATLLGQRWSSNHLAPPKPMSLKTERINSGKT 100 110 120 130 140 150 190 200 210 pF1KB6 PPQENRDKNLSRRRQDRRATPTGRPTPCAERRGGV ::::.:.:. ::::: .::::::: ::::: NP_004 PPQEDREKSPPGRRQDRSPAPTGRPTPGAERRGVSEDGKIMHPSSRSPQNSGGRKSPVQA 160 170 180 190 200 210 NP_004 SQATTLQEQTAAARGADRSSSVLGSSEGGFLSRVQADEFASSAPDSAERQNLPVNPPSSL 220 230 240 250 260 270 >>XP_011534387 (OMIM: 187020) PREDICTED: T-complex prote (329 aa) initn: 916 init1: 916 opt: 916 Z-score: 841.9 bits: 163.5 E(85289): 3.7e-40 Smith-Waterman score: 916; 75.8% identity (87.1% similar) in 186 aa overlap (28-213:1-186) 10 20 30 40 50 60 pF1KB6 MLAGQLEARDPKEGTHPEDPCPGAGAVMEKTAVAAEVLTEDCNTGEMPPLQQQIIRLHQE :::: .:::: :: :.:::: ::::: :::: XP_011 MEKTPAAAEVPREDSNAGEMPSLQQQITSLHQE 10 20 30 70 80 90 100 110 120 pF1KB6 LGRQKSLWADVHGKLRSHIDALREQNMELREKLRALQLQRWKARKKSAASPHAGQESHTL ::::.:::::.: ::.::.::::.:: ::::.::.:: :.:.: :: :::::::.::::: XP_011 LGRQQSLWADIHRKLQSHMDALRKQNRELREELRGLQRQQWEAGKKPAASPHAGRESHTL 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB6 ALEPAFGKISPLSADEETIPKYAGHKNQSATLLGQRSSSNNSAPPKPMSLKIERISSWKT :::::::::: :::::.: :::::.:.::::::::: :::. ::::::::: :::.: :: XP_011 ALEPAFGKISHLSADEDTTPKYAGRKSQSATLLGQRWSSNHLAPPKPMSLKTERINSGKT 100 110 120 130 140 150 190 200 210 pF1KB6 PPQENRDKNLSRRRQDRRATPTGRPTPCAERRGGV ::::.:.:. ::::: .::::::: ::::: XP_011 PPQEDREKSPPGRRQDRSPAPTGRPTPGAERRGVSEDGKIMHPSSRSPQNSGGRKSPVQA 160 170 180 190 200 210 XP_011 SQATTLQEQTAAARGAGEQDRSSSVLGSSEGGFLSRVQADEFASSAPDSAERQNLPVNPP 220 230 240 250 260 270 >>XP_011534386 (OMIM: 187020) PREDICTED: T-complex prote (329 aa) initn: 916 init1: 916 opt: 916 Z-score: 841.9 bits: 163.5 E(85289): 3.7e-40 Smith-Waterman score: 916; 75.8% identity (87.1% similar) in 186 aa overlap (28-213:1-186) 10 20 30 40 50 60 pF1KB6 MLAGQLEARDPKEGTHPEDPCPGAGAVMEKTAVAAEVLTEDCNTGEMPPLQQQIIRLHQE :::: .:::: :: :.:::: ::::: :::: XP_011 MEKTPAAAEVPREDSNAGEMPSLQQQITSLHQE 10 20 30 70 80 90 100 110 120 pF1KB6 LGRQKSLWADVHGKLRSHIDALREQNMELREKLRALQLQRWKARKKSAASPHAGQESHTL ::::.:::::.: ::.::.::::.:: ::::.::.:: :.:.: :: :::::::.::::: XP_011 LGRQQSLWADIHRKLQSHMDALRKQNRELREELRGLQRQQWEAGKKPAASPHAGRESHTL 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB6 ALEPAFGKISPLSADEETIPKYAGHKNQSATLLGQRSSSNNSAPPKPMSLKIERISSWKT :::::::::: :::::.: :::::.:.::::::::: :::. ::::::::: :::.: :: XP_011 ALEPAFGKISHLSADEDTTPKYAGRKSQSATLLGQRWSSNHLAPPKPMSLKTERINSGKT 100 110 120 130 140 150 190 200 210 pF1KB6 PPQENRDKNLSRRRQDRRATPTGRPTPCAERRGGV ::::.:.:. ::::: .::::::: ::::: XP_011 PPQEDREKSPPGRRQDRSPAPTGRPTPGAERRGVSEDGKIMHPSSRSPQNSGGRKSPVQA 160 170 180 190 200 210 XP_011 SQATTLQEQTAAARGAGEQDRSSSVLGSSEGGFLSRVQADEFASSAPDSAERQNLPVNPP 220 230 240 250 260 270 >>XP_016866720 (OMIM: 187020) PREDICTED: T-complex prote (390 aa) initn: 916 init1: 916 opt: 916 Z-score: 840.9 bits: 163.5 E(85289): 4.3e-40 Smith-Waterman score: 916; 75.8% identity (87.1% similar) in 186 aa overlap (28-213:1-186) 10 20 30 40 50 60 pF1KB6 MLAGQLEARDPKEGTHPEDPCPGAGAVMEKTAVAAEVLTEDCNTGEMPPLQQQIIRLHQE :::: .:::: :: :.:::: ::::: :::: XP_016 MEKTPAAAEVPREDSNAGEMPSLQQQITSLHQE 10 20 30 70 80 90 100 110 120 pF1KB6 LGRQKSLWADVHGKLRSHIDALREQNMELREKLRALQLQRWKARKKSAASPHAGQESHTL ::::.:::::.: ::.::.::::.:: ::::.::.:: :.:.: :: :::::::.::::: XP_016 LGRQQSLWADIHRKLQSHMDALRKQNRELREELRGLQRQQWEAGKKPAASPHAGRESHTL 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB6 ALEPAFGKISPLSADEETIPKYAGHKNQSATLLGQRSSSNNSAPPKPMSLKIERISSWKT :::::::::: :::::.: :::::.:.::::::::: :::. ::::::::: :::.: :: XP_016 ALEPAFGKISHLSADEDTTPKYAGRKSQSATLLGQRWSSNHLAPPKPMSLKTERINSGKT 100 110 120 130 140 150 190 200 210 pF1KB6 PPQENRDKNLSRRRQDRRATPTGRPTPCAERRGGV ::::.:.:. ::::: .::::::: ::::: XP_016 PPQEDREKSPPGRRQDRSPAPTGRPTPGAERRGVSEDGKIMHPSSRSPQNSGGRKSPVQA 160 170 180 190 200 210 XP_016 SQATTLQEQTAAARGADRSSSVLGSSEGGFLSRVQADEFASSAPDSAERQVEKFYPNGSK 220 230 240 250 260 270 >>XP_011534390 (OMIM: 187020) PREDICTED: T-complex prote (278 aa) initn: 665 init1: 665 opt: 665 Z-score: 615.7 bits: 121.4 E(85289): 1.5e-27 Smith-Waterman score: 665; 76.3% identity (88.1% similar) in 135 aa overlap (79-213:1-135) 50 60 70 80 90 100 pF1KB6 PLQQQIIRLHQELGRQKSLWADVHGKLRSHIDALREQNMELREKLRALQLQRWKARKKSA .::::.:: ::::.::.:: :.:.: :: : XP_011 MDALRKQNRELREELRGLQRQQWEAGKKPA 10 20 30 110 120 130 140 150 160 pF1KB6 ASPHAGQESHTLALEPAFGKISPLSADEETIPKYAGHKNQSATLLGQRSSSNNSAPPKPM ::::::.::::::::::::::: :::::.: :::::.:.::::::::: :::. :::::: XP_011 ASPHAGRESHTLALEPAFGKISHLSADEDTTPKYAGRKSQSATLLGQRWSSNHLAPPKPM 40 50 60 70 80 90 170 180 190 200 210 pF1KB6 SLKIERISSWKTPPQENRDKNLSRRRQDRRATPTGRPTPCAERRGGV ::: :::.: ::::::.:.:. ::::: .::::::: ::::: XP_011 SLKTERINSGKTPPQEDREKSPPGRRQDRSPAPTGRPTPGAERRGVSEDGKIMHPSSRSP 100 110 120 130 140 150 XP_011 QNSGGRKSPVQASQATTLQEQTAAARGAGEQDRSSSVLGSSEGGFLSRVQADEFASSAPD 160 170 180 190 200 210 >>XP_011534384 (OMIM: 187020) PREDICTED: T-complex prote (335 aa) initn: 467 init1: 467 opt: 471 Z-score: 439.0 bits: 88.9 E(85289): 1e-17 Smith-Waterman score: 471; 73.1% identity (84.6% similar) in 104 aa overlap (113-213:89-192) 90 100 110 120 130 pF1KB6 REQNMELREKLRALQLQRWKARKKSAASPHAGQES---HTLALEPAFGKISPLSADEETI ::.:. . ::::::::::: :::::.: XP_011 PLGGAGKKKLSQGCEDRGPLPTSTETVPIPAGKEQPGIRLLALEPAFGKISHLSADEDTT 60 70 80 90 100 110 140 150 160 170 180 190 pF1KB6 PKYAGHKNQSATLLGQRSSSNNSAPPKPMSLKIERISSWKTPPQENRDKNLSRRRQDRRA :::::.:.::::::::: :::. ::::::::: :::.: ::::::.:.:. ::::: XP_011 PKYAGRKSQSATLLGQRWSSNHLAPPKPMSLKTERINSGKTPPQEDREKSPPGRRQDRSP 120 130 140 150 160 170 200 210 pF1KB6 TPTGRPTPCAERRGGV .::::::: ::::: XP_011 APTGRPTPGAERRGVSEDGKIMHPSSRSPQNSGGRKSPVQASQATTLQEQTAAARGAGEQ 180 190 200 210 220 230 215 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 11:10:04 2016 done: Fri Nov 4 11:10:05 2016 Total Scan time: 6.180 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]