Result of FASTA (omim) for
pF1KB6970
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6970, 241 aa
1>>>pF1KB6970 241 - 241 aa - 241 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2803+/-0.00041; mu= 14.2970+/- 0.026
mean_var=59.3623+/-12.087, 0's: 0 Z-trim(110.4): 37 B-trim: 1035 in 1/48
Lambda= 0.166463
statistics sampled from 18736 (18771) to 18736 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.608), E-opt: 0.2 (0.22), width: 16
Scan time: 4.780
The best scores are: opt bits E(85289)
NP_002781 (OMIM: 176844) proteasome subunit alpha ( 241) 1538 377.8 9.2e-105
NP_001186702 (OMIM: 176844) proteasome subunit alp ( 183) 1173 290.1 1.8e-78
NP_001186703 (OMIM: 176844) proteasome subunit alp ( 183) 1173 290.1 1.8e-78
NP_001186701 (OMIM: 176844) proteasome subunit alp ( 183) 1173 290.1 1.8e-78
NP_002783 (OMIM: 606607) proteasome subunit alpha ( 248) 497 127.8 1.7e-29
NP_002778 (OMIM: 176842) proteasome subunit alpha ( 234) 450 116.5 4e-26
NP_002780 (OMIM: 176846) proteasome subunit alpha ( 261) 437 113.4 3.9e-25
NP_001096137 (OMIM: 176846) proteasome subunit alp ( 261) 437 113.4 3.9e-25
NP_001317605 (OMIM: 176846) proteasome subunit alp ( 261) 437 113.4 3.9e-25
NP_002779 (OMIM: 176843) proteasome subunit alpha ( 255) 426 110.8 2.4e-24
NP_002777 (OMIM: 602854) proteasome subunit alpha ( 263) 411 107.2 3e-23
NP_683877 (OMIM: 602854) proteasome subunit alpha ( 269) 410 106.9 3.6e-23
NP_002782 (OMIM: 602855,608446) proteasome subunit ( 246) 403 105.2 1.1e-22
NP_001317602 (OMIM: 176846) proteasome subunit alp ( 174) 345 91.3 1.2e-18
NP_001269163 (OMIM: 602855,608446) proteasome subu ( 227) 318 84.8 1.4e-16
NP_687033 (OMIM: 176843) proteasome subunit alpha ( 248) 309 82.7 6.6e-16
NP_001317604 (OMIM: 176846) proteasome subunit alp ( 230) 288 77.6 2e-14
NP_001096138 (OMIM: 176846) proteasome subunit alp ( 190) 267 72.5 5.7e-13
NP_001137409 (OMIM: 602854) proteasome subunit alp ( 130) 255 69.6 3e-12
NP_001269162 (OMIM: 602855,608446) proteasome subu ( 167) 217 60.5 2.1e-09
XP_016876957 (OMIM: 602855,608446) PREDICTED: prot ( 167) 217 60.5 2.1e-09
NP_001269161 (OMIM: 602855,608446) proteasome subu ( 167) 217 60.5 2.1e-09
NP_002792 (OMIM: 176847) proteasome subunit beta t ( 273) 145 43.3 0.00052
NP_002791 (OMIM: 177045) proteasome subunit beta t ( 219) 134 40.6 0.0027
NP_002790 (OMIM: 604030) proteasome subunit beta t ( 277) 128 39.2 0.0089
>>NP_002781 (OMIM: 176844) proteasome subunit alpha type (241 aa)
initn: 1538 init1: 1538 opt: 1538 Z-score: 2001.8 bits: 377.8 E(85289): 9.2e-105
Smith-Waterman score: 1538; 100.0% identity (100.0% similar) in 241 aa overlap (1-241:1-241)
10 20 30 40 50 60
pF1KB6 MFLTRSEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MFLTRSEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLME
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 PSSIEKIVEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PSSIEKIVEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 LQFGEEDADPGAMSRPFGVALLFGGVDEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LQFGEEDADPGAMSRPFGVALLFGGVDEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 LQEVYHKSMTLKEAIKSSLIILKQVMEEKLNATNIELATVQPGQNFHMFTKEELEEVIKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LQEVYHKSMTLKEAIKSSLIILKQVMEEKLNATNIELATVQPGQNFHMFTKEELEEVIKD
190 200 210 220 230 240
pF1KB6 I
:
NP_002 I
>>NP_001186702 (OMIM: 176844) proteasome subunit alpha t (183 aa)
initn: 1173 init1: 1173 opt: 1173 Z-score: 1530.0 bits: 290.1 E(85289): 1.8e-78
Smith-Waterman score: 1173; 100.0% identity (100.0% similar) in 183 aa overlap (59-241:1-183)
30 40 50 60 70 80
pF1KB6 EAIKLGSTAIGIQTSEGVCLAVEKRITSPLMEPSSIEKIVEIDAHIGCAMSGLIADAKTL
::::::::::::::::::::::::::::::
NP_001 MEPSSIEKIVEIDAHIGCAMSGLIADAKTL
10 20 30
90 100 110 120 130 140
pF1KB6 IDKARVETQNHWFTYNETMTVESVTQAVSNLALQFGEEDADPGAMSRPFGVALLFGGVDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDKARVETQNHWFTYNETMTVESVTQAVSNLALQFGEEDADPGAMSRPFGVALLFGGVDE
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB6 KGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHKSMTLKEAIKSSLIILKQVMEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHKSMTLKEAIKSSLIILKQVMEE
100 110 120 130 140 150
210 220 230 240
pF1KB6 KLNATNIELATVQPGQNFHMFTKEELEEVIKDI
:::::::::::::::::::::::::::::::::
NP_001 KLNATNIELATVQPGQNFHMFTKEELEEVIKDI
160 170 180
>>NP_001186703 (OMIM: 176844) proteasome subunit alpha t (183 aa)
initn: 1173 init1: 1173 opt: 1173 Z-score: 1530.0 bits: 290.1 E(85289): 1.8e-78
Smith-Waterman score: 1173; 100.0% identity (100.0% similar) in 183 aa overlap (59-241:1-183)
30 40 50 60 70 80
pF1KB6 EAIKLGSTAIGIQTSEGVCLAVEKRITSPLMEPSSIEKIVEIDAHIGCAMSGLIADAKTL
::::::::::::::::::::::::::::::
NP_001 MEPSSIEKIVEIDAHIGCAMSGLIADAKTL
10 20 30
90 100 110 120 130 140
pF1KB6 IDKARVETQNHWFTYNETMTVESVTQAVSNLALQFGEEDADPGAMSRPFGVALLFGGVDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDKARVETQNHWFTYNETMTVESVTQAVSNLALQFGEEDADPGAMSRPFGVALLFGGVDE
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB6 KGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHKSMTLKEAIKSSLIILKQVMEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHKSMTLKEAIKSSLIILKQVMEE
100 110 120 130 140 150
210 220 230 240
pF1KB6 KLNATNIELATVQPGQNFHMFTKEELEEVIKDI
:::::::::::::::::::::::::::::::::
NP_001 KLNATNIELATVQPGQNFHMFTKEELEEVIKDI
160 170 180
>>NP_001186701 (OMIM: 176844) proteasome subunit alpha t (183 aa)
initn: 1173 init1: 1173 opt: 1173 Z-score: 1530.0 bits: 290.1 E(85289): 1.8e-78
Smith-Waterman score: 1173; 100.0% identity (100.0% similar) in 183 aa overlap (59-241:1-183)
30 40 50 60 70 80
pF1KB6 EAIKLGSTAIGIQTSEGVCLAVEKRITSPLMEPSSIEKIVEIDAHIGCAMSGLIADAKTL
::::::::::::::::::::::::::::::
NP_001 MEPSSIEKIVEIDAHIGCAMSGLIADAKTL
10 20 30
90 100 110 120 130 140
pF1KB6 IDKARVETQNHWFTYNETMTVESVTQAVSNLALQFGEEDADPGAMSRPFGVALLFGGVDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDKARVETQNHWFTYNETMTVESVTQAVSNLALQFGEEDADPGAMSRPFGVALLFGGVDE
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB6 KGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHKSMTLKEAIKSSLIILKQVMEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHKSMTLKEAIKSSLIILKQVMEE
100 110 120 130 140 150
210 220 230 240
pF1KB6 KLNATNIELATVQPGQNFHMFTKEELEEVIKDI
:::::::::::::::::::::::::::::::::
NP_001 KLNATNIELATVQPGQNFHMFTKEELEEVIKDI
160 170 180
>>NP_002783 (OMIM: 606607) proteasome subunit alpha type (248 aa)
initn: 505 init1: 337 opt: 497 Z-score: 650.5 bits: 127.8 E(85289): 1.7e-29
Smith-Waterman score: 506; 37.9% identity (71.7% similar) in 240 aa overlap (8-241:3-232)
10 20 30 40 50 60
pF1KB6 MFLTRSEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLME
:::....:::.:.::::::: ::.: ::::.:.. . : :.:::. .. :..
NP_002 MSYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQD
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 PSSIEKIVEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLA
...:: .: .. :..:: :::. .:..:::: :.: .: .. .::: .:. ...:
NP_002 ERTVRKICALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLK
60 70 80 90 100 110
130 140 150 160 170
pF1KB6 LQFGEEDADPGAMSRPFGVALLFGGVDEKG-PQLFHMDPSGTFVQCDARAIGSASEGAQS
.. . .. ::::.. :. : : : :.:.. :::::. : ::: .::.:
NP_002 QRYTQSNG-----RRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIG---RGAKS
120 130 140 150 160
180 190 200 210 220 230
pF1KB6 SLQEVYHKSMTLKEAIKSSLIILKQVMEEKLNAT-----NIELATVQPGQNFHMFTKEEL
..: .:..: :::... . .: :.. :... :::::... :...... ::.
NP_002 -VREFLEKNYT-DEAIETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQSLKILNPEEI
170 180 190 200 210 220
240
pF1KB6 EEVIKDI
:. . .:
NP_002 EKYVAEIEKEKEENEKKKQKKAS
230 240
>>NP_002778 (OMIM: 176842) proteasome subunit alpha type (234 aa)
initn: 413 init1: 234 opt: 450 Z-score: 589.9 bits: 116.5 E(85289): 4e-26
Smith-Waterman score: 450; 32.5% identity (70.9% similar) in 234 aa overlap (8-241:6-233)
10 20 30 40 50 60
pF1KB6 MFLTRSEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLME
:. ...:::: :.: :.:::. :. :. ..::....:: ::.::. : :..
NP_002 MAERGYSFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYD
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 PSSIEKIVEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLA
:..:. : ::: ..::. : ..:. .:: .:.....:.: . . ...: :...
NP_002 ERSVHKVEPITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVM
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 LQFGEEDADPGAMSRPFGVALLFGGVDEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSS
.: .. :.. :::::.::. : .: : ::. ::::.. : :.:. ....
NP_002 ----QEYTQSGGV-RPFGVSLLICGWNEGRPYLFQSDPSGAYFAWKATAMGKNYVNGKTF
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB6 LQEVYHKSMTLKEAIKSSLIILKQVMEEKLNATNIELATVQPGQNFHMFTKEELEEVIKD
:.. :.... :..::..... ::. .: ... :::.. . . .:. .: :... .
NP_002 LEKRYNEDLELEDAIHTAILTLKESFEGQMTEDNIEVGICNEA-GFRRLTPTEVKDYLAA
180 190 200 210 220 230
pF1KB6 I
:
NP_002 IA
>>NP_002780 (OMIM: 176846) proteasome subunit alpha type (261 aa)
initn: 308 init1: 165 opt: 437 Z-score: 572.3 bits: 113.4 E(85289): 3.9e-25
Smith-Waterman score: 437; 36.0% identity (69.8% similar) in 242 aa overlap (8-239:5-238)
10 20 30 40 50 60
pF1KB6 MFLTRSEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLME
:: .. :::::::.:::::.::: ..: .:: ...:: ::.:.: :..
NP_002 MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLD
10 20 30 40 50
70 80 90 100 110
pF1KB6 PSSI-EKIVEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNL
. ::: ... ..:...:. .::..: .. :. .: . . :.: . :... :. ..
NP_002 EVFFSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 A---LQFGEEDADPGAMSRPFGVALLFGGVDEK-GPQLFHMDPSGTFVQCDARAIGSASE
::: : .:::::.::. : :.. : ::.. ::::.. : ::. :
NP_002 KQAYTQFG------G--KRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSA
120 130 140 150 160
180 190 200 210 220 230
pF1KB6 GAQSSLQEVYHKS-MTLKEAIKSSLIILKQVME-EKLNATNIELATV--QPGQN-FHMFT
.: : :.. :... :::: :. .. .:...:. ::.: ..:.::. . :.. ....
NP_002 AAVSMLKQDYKEGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLK
170 180 190 200 210 220
240
pF1KB6 KEELEEVIKDI
..:.:..::
NP_002 QKEVEQLIKKHEEEEAKAEREKKEKEQKEKDK
230 240 250 260
>>NP_001096137 (OMIM: 176846) proteasome subunit alpha t (261 aa)
initn: 308 init1: 165 opt: 437 Z-score: 572.3 bits: 113.4 E(85289): 3.9e-25
Smith-Waterman score: 437; 36.0% identity (69.8% similar) in 242 aa overlap (8-239:5-238)
10 20 30 40 50 60
pF1KB6 MFLTRSEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLME
:: .. :::::::.:::::.::: ..: .:: ...:: ::.:.: :..
NP_001 MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLD
10 20 30 40 50
70 80 90 100 110
pF1KB6 PSSI-EKIVEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNL
. ::: ... ..:...:. .::..: .. :. .: . . :.: . :... :. ..
NP_001 EVFFSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 A---LQFGEEDADPGAMSRPFGVALLFGGVDEK-GPQLFHMDPSGTFVQCDARAIGSASE
::: : .:::::.::. : :.. : ::.. ::::.. : ::. :
NP_001 KQAYTQFG------G--KRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSA
120 130 140 150 160
180 190 200 210 220 230
pF1KB6 GAQSSLQEVYHKS-MTLKEAIKSSLIILKQVME-EKLNATNIELATV--QPGQN-FHMFT
.: : :.. :... :::: :. .. .:...:. ::.: ..:.::. . :.. ....
NP_001 AAVSMLKQDYKEGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLK
170 180 190 200 210 220
240
pF1KB6 KEELEEVIKDI
..:.:..::
NP_001 QKEVEQLIKKHEEEEAKAEREKKEKEQKEKDK
230 240 250 260
>>NP_001317605 (OMIM: 176846) proteasome subunit alpha t (261 aa)
initn: 308 init1: 165 opt: 437 Z-score: 572.3 bits: 113.4 E(85289): 3.9e-25
Smith-Waterman score: 437; 36.0% identity (69.8% similar) in 242 aa overlap (8-239:5-238)
10 20 30 40 50 60
pF1KB6 MFLTRSEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLME
:: .. :::::::.:::::.::: ..: .:: ...:: ::.:.: :..
NP_001 MSRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLD
10 20 30 40 50
70 80 90 100 110
pF1KB6 PSSI-EKIVEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNL
. ::: ... ..:...:. .::..: .. :. .: . . :.: . :... :. ..
NP_001 EVFFSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 A---LQFGEEDADPGAMSRPFGVALLFGGVDEK-GPQLFHMDPSGTFVQCDARAIGSASE
::: : .:::::.::. : :.. : ::.. ::::.. : ::. :
NP_001 KQAYTQFG------G--KRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSA
120 130 140 150 160
180 190 200 210 220 230
pF1KB6 GAQSSLQEVYHKS-MTLKEAIKSSLIILKQVME-EKLNATNIELATV--QPGQN-FHMFT
.: : :.. :... :::: :. .. .:...:. ::.: ..:.::. . :.. ....
NP_001 AAVSMLKQDYKEGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLK
170 180 190 200 210 220
240
pF1KB6 KEELEEVIKDI
..:.:..::
NP_001 QKEVEQLIKKHEEEEAKAEREKKEKEQKEKDK
230 240 250 260
>>NP_002779 (OMIM: 176843) proteasome subunit alpha type (255 aa)
initn: 415 init1: 302 opt: 426 Z-score: 558.2 bits: 110.8 E(85289): 2.4e-24
Smith-Waterman score: 426; 34.1% identity (68.5% similar) in 232 aa overlap (8-236:8-234)
10 20 30 40 50 60
pF1KB6 MFLTRSEYDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLME
:: ...::::.::.::::::..:.. .::::::. ..:: ..::: . : :.:
NP_002 MSSIGTGYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 PSSIEKIVEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLA
.: ... ..: :.: :..::.:::..: : :: :..: ... .. .. ... :. .
NP_002 EGSNKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYV
70 80 90 100 110 120
130 140 150 160 170
pF1KB6 LQFGEEDADPGAMSRPFGVALLFGGVD-EKGPQLFHMDPSGTFVQCDARAIGSASEGAQS
. .: :::: ....:. . . : ::. .::::. . :::.: ..:..
NP_002 HAYTLYSA-----VRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKT
130 140 150 160 170
180 190 200 210 220 230
pF1KB6 SLQEVYHKSMTLKEAIKSSLIILKQVMEE-KLNATNIELATVQPGQN-FHMFTKEELEEV
.... : :: .. .: :. : .: : .: ..::. : : : .. ....:
NP_002 EIEKLQMKEMTCRDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREE
180 190 200 210 220 230
240
pF1KB6 IKDI
NP_002 AEKYAKESLKEEDESDDDNM
240 250
241 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 11:04:51 2016 done: Fri Nov 4 11:04:52 2016
Total Scan time: 4.780 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]