Result of FASTA (omim) for
pF1KB6979
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6979, 218 aa
1>>>pF1KB6979 218 - 218 aa - 218 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.0414+/-0.00026; mu= 6.5532+/- 0.016
mean_var=101.0666+/-19.624, 0's: 0 Z-trim(122.6): 41 B-trim: 0 in 0/54
Lambda= 0.127576
statistics sampled from 40946 (40987) to 40946 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.811), E-opt: 0.2 (0.481), width: 16
Scan time: 7.230
The best scores are: opt bits E(85289)
NP_004315 (OMIM: 600040) apoptosis regulator BAX i ( 218) 1516 288.3 6.8e-78
NP_001278358 (OMIM: 600040) apoptosis regulator BA ( 181) 1267 242.4 3.6e-64
NP_001278357 (OMIM: 600040) apoptosis regulator BA ( 221) 1078 207.7 1.3e-53
NP_620116 (OMIM: 600040) apoptosis regulator BAX i ( 192) 1073 206.7 2.1e-53
NP_620119 (OMIM: 600040) apoptosis regulator BAX i ( 179) 1070 206.2 2.9e-53
NP_001278359 (OMIM: 600040) apoptosis regulator BA ( 140) 996 192.5 2.9e-49
XP_016882566 (OMIM: 600040) PREDICTED: apoptosis r ( 173) 940 182.2 4.5e-46
NP_620118 (OMIM: 600040) apoptosis regulator BAX i ( 143) 562 112.6 3.3e-25
NP_001278360 (OMIM: 600040) apoptosis regulator BA ( 114) 553 110.9 8.6e-25
NP_000624 (OMIM: 151430) apoptosis regulator Bcl-2 ( 239) 209 47.7 1.9e-05
NP_000648 (OMIM: 151430) apoptosis regulator Bcl-2 ( 205) 207 47.3 2.2e-05
XP_016881406 (OMIM: 151430) PREDICTED: apoptosis r ( 198) 205 47.0 2.7e-05
XP_011513081 (OMIM: 600516) PREDICTED: bcl-2 homol ( 211) 205 47.0 2.8e-05
NP_001179 (OMIM: 600516) bcl-2 homologous antagoni ( 211) 205 47.0 2.8e-05
NP_115904 (OMIM: 605404) bcl-2-related ovarian kil ( 212) 205 47.0 2.9e-05
XP_011509998 (OMIM: 605404) PREDICTED: bcl-2-relat ( 212) 205 47.0 2.9e-05
XP_011524437 (OMIM: 151430) PREDICTED: apoptosis r ( 224) 202 46.4 4.4e-05
NP_001309171 (OMIM: 600039) bcl-2-like protein 1 i ( 233) 201 46.2 5.2e-05
XP_016883482 (OMIM: 600039) PREDICTED: bcl-2-like ( 233) 201 46.2 5.2e-05
NP_001304849 (OMIM: 600039) bcl-2-like protein 1 i ( 233) 201 46.2 5.2e-05
NP_001304848 (OMIM: 600039) bcl-2-like protein 1 i ( 233) 201 46.2 5.2e-05
NP_001309169 (OMIM: 600039) bcl-2-like protein 1 i ( 233) 201 46.2 5.2e-05
XP_011527266 (OMIM: 600039) PREDICTED: bcl-2-like ( 233) 201 46.2 5.2e-05
NP_001309168 (OMIM: 600039) bcl-2-like protein 1 i ( 233) 201 46.2 5.2e-05
NP_001304850 (OMIM: 600039) bcl-2-like protein 1 i ( 233) 201 46.2 5.2e-05
NP_612815 (OMIM: 600039) bcl-2-like protein 1 isof ( 233) 201 46.2 5.2e-05
NP_001186768 (OMIM: 601931) bcl-2-like protein 2 [ ( 193) 193 44.7 0.00012
NP_004041 (OMIM: 601931) bcl-2-like protein 2 [Hom ( 193) 193 44.7 0.00012
XP_011513082 (OMIM: 600516) PREDICTED: bcl-2 homol ( 152) 182 42.7 0.0004
NP_001108207 (OMIM: 601056) bcl-2-related protein ( 163) 175 41.4 0.001
NP_004040 (OMIM: 601056) bcl-2-related protein A1 ( 175) 175 41.4 0.0011
NP_001184249 (OMIM: 159552) induced myeloid leukem ( 197) 174 41.3 0.0014
NP_068779 (OMIM: 159552) induced myeloid leukemia ( 350) 172 41.0 0.003
>>NP_004315 (OMIM: 600040) apoptosis regulator BAX isofo (218 aa)
initn: 1516 init1: 1516 opt: 1516 Z-score: 1519.5 bits: 288.3 E(85289): 6.8e-78
Smith-Waterman score: 1516; 100.0% identity (100.0% similar) in 218 aa overlap (1-218:1-218)
10 20 30 40 50 60
pF1KB6 MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 ECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 VLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWVRLLKPPHPHHRALTTAPAPPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWVRLLKPPHPHHRALTTAPAPPS
130 140 150 160 170 180
190 200 210
pF1KB6 LPPATPLGPWAFWSRSQWCPLPIFRSSDVVYNAFSLRV
::::::::::::::::::::::::::::::::::::::
NP_004 LPPATPLGPWAFWSRSQWCPLPIFRSSDVVYNAFSLRV
190 200 210
>>NP_001278358 (OMIM: 600040) apoptosis regulator BAX ga (181 aa)
initn: 1267 init1: 1267 opt: 1267 Z-score: 1273.1 bits: 242.4 E(85289): 3.6e-64
Smith-Waterman score: 1267; 100.0% identity (100.0% similar) in 181 aa overlap (38-218:1-181)
10 20 30 40 50 60
pF1KB6 PRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLSECLKRIG
::::::::::::::::::::::::::::::
NP_001 MGGEAPELALDPVPQDASTKKLSECLKRIG
10 20 30
70 80 90 100 110 120
pF1KB6 DELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKLVLKALCT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKLVLKALCT
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB6 KVPELIRTIMGWTLDFLRERLLGWIQDQGGWVRLLKPPHPHHRALTTAPAPPSLPPATPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KVPELIRTIMGWTLDFLRERLLGWIQDQGGWVRLLKPPHPHHRALTTAPAPPSLPPATPL
100 110 120 130 140 150
190 200 210
pF1KB6 GPWAFWSRSQWCPLPIFRSSDVVYNAFSLRV
:::::::::::::::::::::::::::::::
NP_001 GPWAFWSRSQWCPLPIFRSSDVVYNAFSLRV
160 170 180
>>NP_001278357 (OMIM: 600040) apoptosis regulator BAX is (221 aa)
initn: 1070 init1: 1070 opt: 1078 Z-score: 1083.7 bits: 207.7 E(85289): 1.3e-53
Smith-Waterman score: 1078; 90.1% identity (93.4% similar) in 181 aa overlap (1-181:1-179)
10 20 30 40 50 60
pF1KB6 MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 ECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 VLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWVRLLKPPHPHHRALTTAPAPPS
:::::::::::::::::::::::::::::::::::::: : . .: .. .:. :
NP_001 VLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGW--GLPLAESLKRLMSLSPGRPP
130 140 150 160 170
190 200 210
pF1KB6 LPPATPLGPWAFWSRSQWCPLPIFRSSDVVYNAFSLRV
:
NP_001 LLLWDAHVADRDHLCGGSAHRLTHHLEEDGLRPPAALDCVFPP
180 190 200 210 220
>>NP_620116 (OMIM: 600040) apoptosis regulator BAX isofo (192 aa)
initn: 1073 init1: 1073 opt: 1073 Z-score: 1079.7 bits: 206.7 E(85289): 2.1e-53
Smith-Waterman score: 1073; 98.8% identity (98.8% similar) in 162 aa overlap (1-162:1-162)
10 20 30 40 50 60
pF1KB6 MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 ECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 ECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 VLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWVRLLKPPHPHHRALTTAPAPPS
:::::::::::::::::::::::::::::::::::::: ::
NP_620 VLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTPTWQTVTIFVAGV
130 140 150 160 170 180
190 200 210
pF1KB6 LPPATPLGPWAFWSRSQWCPLPIFRSSDVVYNAFSLRV
NP_620 LTASLTIWKKMG
190
>>NP_620119 (OMIM: 600040) apoptosis regulator BAX isofo (179 aa)
initn: 1070 init1: 1070 opt: 1070 Z-score: 1077.2 bits: 206.2 E(85289): 2.9e-53
Smith-Waterman score: 1070; 100.0% identity (100.0% similar) in 158 aa overlap (1-158:1-158)
10 20 30 40 50 60
pF1KB6 MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 ECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 ECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 VLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWVRLLKPPHPHHRALTTAPAPPS
::::::::::::::::::::::::::::::::::::::
NP_620 VLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWTVTIFVAGVLTASLTIWKKMG
130 140 150 160 170
190 200 210
pF1KB6 LPPATPLGPWAFWSRSQWCPLPIFRSSDVVYNAFSLRV
>>NP_001278359 (OMIM: 600040) apoptosis regulator BAX is (140 aa)
initn: 996 init1: 996 opt: 996 Z-score: 1005.3 bits: 192.5 E(85289): 2.9e-49
Smith-Waterman score: 996; 100.0% identity (100.0% similar) in 140 aa overlap (79-218:1-140)
50 60 70 80 90 100
pF1KB6 PVPQDASTKKLSECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWG
::::::::::::::::::::::::::::::
NP_001 MIAAVDTDSPREVFFRVAADMFSDGNFNWG
10 20 30
110 120 130 140 150 160
pF1KB6 RVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWVRLLKPPHPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWVRLLKPPHPH
40 50 60 70 80 90
170 180 190 200 210
pF1KB6 HRALTTAPAPPSLPPATPLGPWAFWSRSQWCPLPIFRSSDVVYNAFSLRV
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRALTTAPAPPSLPPATPLGPWAFWSRSQWCPLPIFRSSDVVYNAFSLRV
100 110 120 130 140
>>XP_016882566 (OMIM: 600040) PREDICTED: apoptosis regul (173 aa)
initn: 940 init1: 940 opt: 940 Z-score: 948.1 bits: 182.2 E(85289): 4.5e-46
Smith-Waterman score: 940; 98.6% identity (98.6% similar) in 143 aa overlap (20-162:1-143)
10 20 30 40 50 60
pF1KB6 MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLS
:::::::::::::::::::::::::::::::::::::::::
XP_016 MKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLS
10 20 30 40
70 80 90 100 110 120
pF1KB6 ECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB6 VLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWVRLLKPPHPHHRALTTAPAPPS
:::::::::::::::::::::::::::::::::::::: ::
XP_016 VLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTPTWQTVTIFVAGV
110 120 130 140 150 160
190 200 210
pF1KB6 LPPATPLGPWAFWSRSQWCPLPIFRSSDVVYNAFSLRV
XP_016 LTASLTIWKKMG
170
>>NP_620118 (OMIM: 600040) apoptosis regulator BAX isofo (143 aa)
initn: 562 init1: 562 opt: 562 Z-score: 573.5 bits: 112.6 E(85289): 3.3e-25
Smith-Waterman score: 639; 68.5% identity (68.5% similar) in 162 aa overlap (1-162:1-113)
10 20 30 40 50 60
pF1KB6 MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLS
:::::::::::::::::::::::::::::
NP_620 MDGSGEQPRGGGPTSSEQIMKTGALLLQG-------------------------------
10 20
70 80 90 100 110 120
pF1KB6 ECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL
::::::::::::::::::::::::::::::::::::::::::
NP_620 ------------------MIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKL
30 40 50 60 70
130 140 150 160 170 180
pF1KB6 VLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWVRLLKPPHPHHRALTTAPAPPS
:::::::::::::::::::::::::::::::::::::: ::
NP_620 VLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTPTWQTVTIFVAGV
80 90 100 110 120 130
190 200 210
pF1KB6 LPPATPLGPWAFWSRSQWCPLPIFRSSDVVYNAFSLRV
NP_620 LTASLTIWKKMG
140
>>NP_001278360 (OMIM: 600040) apoptosis regulator BAX is (114 aa)
initn: 553 init1: 553 opt: 553 Z-score: 566.1 bits: 110.9 E(85289): 8.6e-25
Smith-Waterman score: 553; 97.6% identity (97.6% similar) in 84 aa overlap (79-162:1-84)
50 60 70 80 90 100
pF1KB6 PVPQDASTKKLSECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWG
::::::::::::::::::::::::::::::
NP_001 MIAAVDTDSPREVFFRVAADMFSDGNFNWG
10 20 30
110 120 130 140 150 160
pF1KB6 RVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWVRLLKPPHPH
:::::::::::::::::::::::::::::::::::::::::::::::::: ::
NP_001 RVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTP
40 50 60 70 80 90
170 180 190 200 210
pF1KB6 HRALTTAPAPPSLPPATPLGPWAFWSRSQWCPLPIFRSSDVVYNAFSLRV
NP_001 TWQTVTIFVAGVLTASLTIWKKMG
100 110
>>NP_000624 (OMIM: 151430) apoptosis regulator Bcl-2 alp (239 aa)
initn: 162 init1: 162 opt: 209 Z-score: 218.7 bits: 47.7 E(85289): 1.9e-05
Smith-Waterman score: 209; 31.7% identity (59.7% similar) in 139 aa overlap (40-172:79-209)
10 20 30 40 50 60
pF1KB6 GGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLSECLKRIGDE
: : ::.::: . .:. :.. ::
NP_000 FSSQPGHTPHPAASRDPVARTSPLQTPAAPGAAAGPALSPVPP---VVHLT--LRQAGD-
50 60 70 80 90 100
70 80 90 100 110 120
pF1KB6 LDSNMELQRMIAAVDTD---SP---REVFFRVAADMFSDGNFNWGRVVALFYFASKLVLK
: . . .: .: .... .: : : :. ..: :: ::::.::.: :.. . ..
NP_000 -DFSRRYRRDFAEMSSQLHLTPFTARGRFATVVEELFRDG-VNWGRIVAFFEFGGVMCVE
110 120 130 140 150 160
130 140 150 160 170 180
pF1KB6 ALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWVRLLKPPHPHHRALTTAPAPPSLPP
.. .. :. .: : ..: ..: ::::.::: ... : : :
NP_000 SVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTL
170 180 190 200 210 220
190 200 210
pF1KB6 ATPLGPWAFWSRSQWCPLPIFRSSDVVYNAFSLRV
NP_000 LSLALVGACITLGAYLGHK
230
218 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 10:49:33 2016 done: Fri Nov 4 10:49:34 2016
Total Scan time: 7.230 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]